Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia
Willems, Lise, Jacque, Nathalie, Jacquel, Arnaud, Neveux, Nathalie, Trovati Maciel, Thiago, Lambert, Mireille, Schmitt, Alain, Poulain, Laury, Green, Alexa S., Uzunov, Madalina, Kosmider, Olivier, Radford-Weiss, Isabelle, Moura, Ivan Cruz, Auberger, Patrick, Ifrah, Norbert, Bardet, Valérie, Chapuis, Nicolas, Lacombe, Catherine, Mayeux, Patrick, Tamburini, Jérôme, Bouscary, Didier
Published in Blood (14.11.2013)
Published in Blood (14.11.2013)
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Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia
Sujobert, Pierre, Poulain, Laury, Paubelle, Etienne, Zylbersztejn, Florence, Grenier, Adrien, Lambert, Mireille, Townsend, Elizabeth C., Brusq, Jean-Marie, Nicodeme, Edwige, Decrooqc, Justine, Nepstad, Ina, Green, Alexa S., Mondesir, Johanna, Hospital, Marie-Anne, Jacque, Nathalie, Christodoulou, Alexandra, Desouza, Tiffany A., Hermine, Olivier, Foretz, Marc, Viollet, Benoit, Lacombe, Catherine, Mayeux, Patrick, Weinstock, David M., Moura, Ivan C., Bouscary, Didier, Tamburini, Jerome
Published in Cell reports (Cambridge) (09.06.2015)
Published in Cell reports (Cambridge) (09.06.2015)
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Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia
Tamburini, Jerome, Green, Alexa S., Bardet, Valerie, Chapuis, Nicolas, Park, Sophie, Willems, Lise, Uzunov, Madalina, Ifrah, Norbert, Dreyfus, François, Lacombe, Catherine, Mayeux, Patrick, Bouscary, Didier
Published in Blood (20.08.2009)
Published in Blood (20.08.2009)
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Dual Inhibition of PI3K and mTORC1/2 Signaling by NVP-BEZ235 as a New Therapeutic Strategy for Acute Myeloid Leukemia
CHAPUIS, Nicolas, TAMBURINI, Jerome, MAIRA, Sauveur-Michel, IFRAH, Norbert, DREYFUS, François, HERAULT, Olivier, LACOMBE, Catherine, MAYEUX, Patrick, BOUSCARY, Didier, GREEN, Alexa S, VIGNON, Christine, BARDET, Valerie, NEYRET, Aymeric, PANNETIER, Melanie, WILLEMS, Lise, PARK, Sophie, MACONE, Alexandre
Published in Clinical cancer research (15.11.2010)
Published in Clinical cancer research (15.11.2010)
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Autocrine IGF-1/IGF-1R signaling is responsible for constitutive PI3K/Akt activation in acute myeloid leukemia: therapeutic value of neutralizing anti-IGF-1R antibody
CHAPUIS, Nicolas, TAMBURINI, Jérôme, MAYEUX, Patrick, LACOMBE, Catherine, BOUSCARY, Didier, CORNILLET-LEFEBVRE, Pascale, GILLOT, Lucile, BARDET, Valérie, WILLEMS, Lise, PARK, Sophie, GREEN, Alexa S, IFRAH, Norbert, DREYFUS, François
Published in Haematologica (Roma) (01.03.2010)
Published in Haematologica (Roma) (01.03.2010)
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The FLT3 and Pim kinases inhibitor SGI-1776 preferentially target FLT3-ITD AML cells
Hospital, Marie-Anne, Green, Alexa S., Lacombe, Catherine, Mayeux, Patrick, Bouscary, Didier, Tamburini, Jerome
Published in Blood (16.02.2012)
Published in Blood (16.02.2012)
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High levels of CD34+CD38low/−CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucémies Aiguës et Maladies du Sang (GOELAMS) study
VERGEZ, François, GREEN, Alexa S, DREYFUS, François, MANENTI, Stephane, DEMUR, Cecile, DELABESSE, Eric, LACOMBE, Catherine, MAYEUX, Patrick, BOUSCARY, Didier, RECHER, Christian, BARDET, Valerie, TAMBURINI, Jerome, SARRY, Jean-Emmanuel, GAILLARD, Baptiste, CORNILLET-LEFEBVRE, Pascale, PANNETIER, Melanie, NEYRET, Aymeric, CHAPUIS, Nicolas, IFRAH, Norbert
Published in Haematologica (Roma) (01.12.2011)
Published in Haematologica (Roma) (01.12.2011)
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IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia
Chapuis, Nicolas, Park, Sophie, Leotoing, Laurent, Tamburini, Jerome, Verdier, Frederique, Bardet, Valerie, Green, Alexa S., Willems, Lise, Agou, Fabrice, Ifrah, Norbert, Dreyfus, François, Bismuth, Georges, Baud, Veronique, Lacombe, Catherine, Mayeux, Patrick, Bouscary, Didier
Published in Blood (18.11.2010)
Published in Blood (18.11.2010)
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Phenotypic landscape of granulocytes and monocytes by multiparametric flow cytometry: A prospective study of a 1‐tube panel strategy for diagnosis and prognosis of patients with MDS
Barreau, Sylvain, Green, Alexa S., Dussiau, Charles, Alary, Anne‐Sophie, Raimbault, Anna, Mathis, Stephanie, Willems, Lise, Bouscary, Didier, Kosmider, Olivier, Bardet, Valerie, Fontenay, Michaela, Chapuis, Nicolas
Published in Cytometry. Part B, Clinical cytometry (01.05.2020)
Published in Cytometry. Part B, Clinical cytometry (01.05.2020)
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FLT3 inhibitors: clinical potential in acute myeloid leukemia
Hospital, Marie-Anne, Green, Alexa S, Maciel, Thiago T, Moura, Ivan C, Leung, Anskar Y, Bouscary, Didier, Tamburini, Jerome
Published in OncoTargets and therapy (01.01.2017)
Published in OncoTargets and therapy (01.01.2017)
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Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia
Green, Alexa S, Maciel, Thiago T, Hospital, Marie-Anne, Yin, Chae, Mazed, Fetta, Townsend, Elizabeth C, Pilorge, Sylvain, Lambert, Mireille, Paubelle, Etienne, Jacquel, Arnaud, Zylbersztejn, Florence, Decroocq, Justine, Poulain, Laury, Sujobert, Pierre, Jacque, Nathalie, Adam, Kevin, So, Jason C C, Kosmider, Olivier, Auberger, Patrick, Hermine, Olivier, Weinstock, David M, Lacombe, Catherine, Mayeux, Patrick, Vanasse, Gary J, Leung, Anskar Y, Moura, Ivan C, Bouscary, Didier, Tamburini, Jerome
Published in Science advances (01.09.2015)
Published in Science advances (01.09.2015)
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The eukaryotic Initiating Factor 4E protein is overexpressed, but its level has no prognostic impact in acute myeloid leukaemia
Green, Alexa S., Grabar, Sophie, Tulliez, Micheline, Park, Sophie, Al-Nawakil, Chadi, Chapuis, Nicolas, Jacque, Nathalie, Willems, Lise, Azar, Nabih, Ifrah, Norbert, Dreyfus, François, Lacombe, Catherine, Mayeux, Patrick, Bouscary, Didier, Tamburini, Jerome
Published in British journal of haematology (01.02.2012)
Published in British journal of haematology (01.02.2012)
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Journal Article
Co-activation of AMPK and mTORC1 Induce Cytotoxicity in Acute Myeloid Leukemia
Sujobert, Pierre, Poulain, Laury, Paubelle, Etienne, Zylbersztejn, Florence, Grenier, Adrien, Lambert, Mireille, Townsend, Elizabeth C, Brusq, Jean-Marie, Nicodeme, Edwige, Decrooqc, Justine, Nepstad, Ina, Green, Alexa S, Mondesir, Johanna, Hospital, Marie-Anne, Jacque, Nathalie, Christodoulou, Alexandra, Desouza, Tiffany A, Hermine, Olivier, Foretz, Marc, Viollet, Benoit, Lacombe, Catherine, Mayeux, Patrick, Weinstock, David m., Moura, Ivan C, Bouscary, Didier, Tamburini, Jerome
Published in Cell reports (Cambridge) (20.05.2015)
Published in Cell reports (Cambridge) (20.05.2015)
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The LKB 1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation
GREEN, Alexa S, CHAPUIS, Nicolas, VIOLLET, Benoit, IFRAH, Norbert, DREYFUS, François, HERMINE, Olivier, CRUZ MOURA, Ivan, LACOMBE, Catherine, MAYEUX, Patrick, BOUSCARY, Didier, TAMBURINI, Jerome, TROVATI MACIEL, Thiago, WILLEMS, Lise, LAMBERT, Mireille, ARNOULT, Christophe, BOYER, Olivier, BARDET, Valerie, PARK, Sophie, FORETZ, Marc
Published in Blood (2010)
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Published in Blood (2010)
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