Mesenchymal stromal cell apoptosis is required for their therapeutic function
Pang, Swee Heng Milon, D'Rozario, Joshua, Mendonca, Senora, Bhuvan, Tejasvini, Payne, Natalie L, Zheng, Di, Hisana, Assifa, Wallis, Georgia, Barugahare, Adele, Powell, David, Rautela, Jai, Huntington, Nicholas D, Dewson, Grant, Huang, David C S, Gray, Daniel H D, Heng, Tracy S P
Published in Nature communications (11.11.2021)
Published in Nature communications (11.11.2021)
Get full text
Journal Article
p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa
Valente, Liz J., Gray, Daniel H.D., Michalak, Ewa M., Pinon-Hofbauer, Josefina, Egle, Alex, Scott, Clare L., Janic, Ana, Strasser, Andreas
Published in Cell reports (Cambridge) (30.05.2013)
Published in Cell reports (Cambridge) (30.05.2013)
Get full text
Journal Article
Sexually Dimorphic Neurons in the Ventromedial Hypothalamus Govern Mating in Both Sexes and Aggression in Males
Yang, Cindy F., Chiang, Michael C., Gray, Daniel C., Prabhakaran, Mahalakshmi, Alvarado, Maricruz, Juntti, Scott A., Unger, Elizabeth K., Wells, James A., Shah, Nirao M.
Published in Cell (09.05.2013)
Published in Cell (09.05.2013)
Get full text
Journal Article
Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia
Blombery, Piers, Anderson, Mary Ann, Gong, Jia-Nan, Thijssen, Rachel, Birkinshaw, Richard W, Thompson, Ella R, Teh, Charis E, Nguyen, Tamia, Xu, Zhen, Flensburg, Christoffer, Lew, Thomas E, Majewski, Ian J, Gray, Daniel H D, Westerman, David A, Tam, Constantine S, Seymour, John F, Czabotar, Peter E, Huang, David C S, Roberts, Andrew W
Published in Cancer discovery (01.03.2019)
Published in Cancer discovery (01.03.2019)
Get full text
Journal Article
Combined immune checkpoint blockade as a therapeutic strategy for BRCA1 -mutated breast cancer
Nolan, Emma, Savas, Peter, Policheni, Antonia N, Darcy, Phillip K, Vaillant, François, Mintoff, Christopher P, Dushyanthen, Sathana, Mansour, Mariam, Pang, Jia-Min B, Fox, Stephen B, Perou, Charles M, Visvader, Jane E, Gray, Daniel H D, Loi, Sherene, Lindeman, Geoffrey J
Published in Science translational medicine (07.06.2017)
Published in Science translational medicine (07.06.2017)
Get more information
Journal Article
Cell death and thymic tolerance
Daley, Stephen R., Teh, Charis, Hu, Daniel Y., Strasser, Andreas, Gray, Daniel H.D.
Published in Immunological reviews (01.05.2017)
Published in Immunological reviews (01.05.2017)
Get full text
Journal Article
Multilineage Potential and Self-Renewal Define an Epithelial Progenitor Cell Population in the Adult Thymus
Wong, Kahlia, Lister, Natalie L., Barsanti, Marco, Lim, Joanna M.C., Hammett, Maree V., Khong, Danika M., Siatskas, Christopher, Gray, Daniel H.D., Boyd, Richard L., Chidgey, Ann P.
Published in Cell reports (Cambridge) (21.08.2014)
Published in Cell reports (Cambridge) (21.08.2014)
Get full text
Journal Article
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation
Vince, James E., De Nardo, Dominic, Gao, Wenqing, Vince, Angelina J., Hall, Cathrine, McArthur, Kate, Simpson, Daniel, Vijayaraj, Swarna, Lindqvist, Lisa M., Bouillet, Philippe, Rizzacasa, Mark A., Man, Si Ming, Silke, John, Masters, Seth L., Lessene, Guillaume, Huang, David C.S., Gray, Daniel H.D., Kile, Benjamin T., Shao, Feng, Lawlor, Kate E.
Published in Cell reports (Cambridge) (27.11.2018)
Published in Cell reports (Cambridge) (27.11.2018)
Get full text
Journal Article
VDAC2 enables BAX to mediate apoptosis and limit tumor development
Chin, Hui San, Li, Mark X, Tan, Iris K L, Ninnis, Robert L, Reljic, Boris, Scicluna, Kristen, Dagley, Laura F, Sandow, Jarrod J, Kelly, Gemma L, Samson, Andre L, Chappaz, Stephane, Khaw, Seong L, Chang, Catherine, Morokoff, Andrew, Brinkmann, Kerstin, Webb, Andrew, Hockings, Colin, Hall, Cathrine M, Kueh, Andrew J, Ryan, Michael T, Kluck, Ruth M, Bouillet, Philippe, Herold, Marco J, Gray, Daniel H D, Huang, David C S, van Delft, Mark F, Dewson, Grant
Published in Nature communications (26.11.2018)
Published in Nature communications (26.11.2018)
Get full text
Journal Article
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
Jacquelot, Nicolas, Seillet, Cyril, Wang, Minyu, Pizzolla, Angela, Liao, Yang, Hediyeh-Zadeh, Soroor, Grisaru-Tal, Sharon, Louis, Cynthia, Huang, Qiutong, Schreuder, Jaring, Souza-Fonseca-Guimaraes, Fernando, de Graaf, Carolyn A, Thia, Kevin, Macdonald, Sean, Camilleri, Mary, Luong, Kylie, Zhang, Shengbo, Chopin, Michael, Molden-Hauer, Tristan, Nutt, Stephen L, Umansky, Viktor, Ciric, Bogoljub, Groom, Joanna R, Foster, Paul S, Hansbro, Philip M, McKenzie, Andrew N J, Gray, Daniel H D, Behren, Andreas, Cebon, Jonathan, Vivier, Eric, Wicks, Ian P, Trapani, Joseph A, Munitz, Ariel, Davis, Melissa J, Shi, Wei, Neeson, Paul J, Belz, Gabrielle T
Published in Nature immunology (01.07.2021)
Published in Nature immunology (01.07.2021)
Get full text
Journal Article
Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma
Agarwal, Rishu, Chan, Yih-Chih, Tam, Constantine S, Hunter, Tane, Vassiliadis, Dane, Teh, Charis E, Thijssen, Rachel, Yeh, Paul, Wong, Stephen Q, Ftouni, Sarah, Lam, Enid Y N, Anderson, Mary Ann, Pott, Christiane, Gilan, Omer, Bell, Charles C, Knezevic, Kathy, Blombery, Piers, Rayeroux, Kathleen, Zordan, Adrian, Li, Jason, Huang, David C S, Wall, Meaghan, Seymour, John F, Gray, Daniel H D, Roberts, Andrew W, Dawson, Mark A, Dawson, Sarah-Jane
Published in Nature medicine (01.01.2019)
Published in Nature medicine (01.01.2019)
Get full text
Journal Article
Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy
Thijssen, Rachel, Tian, Luyi, Anderson, Mary Ann, Flensburg, Christoffer, Jarratt, Andrew, Garnham, Alexandra L., Jabbari, Jafar S., Peng, Hongke, Lew, Thomas E., Teh, Charis E., Gouil, Quentin, Georgiou, Angela, Tan, Tania, Djajawi, Tirta M., Tam, Constantine S., Seymour, John F., Blombery, Piers, Gray, Daniel H.D., Majewski, Ian J., Ritchie, Matthew E., Roberts, Andrew W., Huang, David C.S.
Published in Blood (17.11.2022)
Published in Blood (17.11.2022)
Get full text
Journal Article
The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens
Gray, Daniel H.D., Kupresanin, Fiona, Berzins, Stuart P., Herold, Marco J., O'Reilly, Lorraine A., Bouillet, Philippe, Strasser, Andreas
Published in Immunity (Cambridge, Mass.) (21.09.2012)
Published in Immunity (Cambridge, Mass.) (21.09.2012)
Get full text
Journal Article
Survival of very preterm infants admitted to neonatal care in England 2008–2014: time trends and regional variation
Santhakumaran, Shalini, Statnikov, Yevgeniy, Gray, Daniel, Battersby, Cheryl, Ashby, Deborah, Modi, Neena
Published in Archives of disease in childhood. Fetal and neonatal edition (01.05.2018)
Published in Archives of disease in childhood. Fetal and neonatal edition (01.05.2018)
Get full text
Journal Article
Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells
Teh, Charis E, Gong, Jia-Nan, Segal, David, Tan, Tania, Vandenberg, Cassandra J, Fedele, Pasquale L, Low, Michael S Y, Grigoriadis, George, Harrison, Simon J, Strasser, Andreas, Roberts, Andrew W, Huang, David C S, Nolan, Garry P, Gray, Daniel H D, Ko, Melissa E
Published in Cell death and differentiation (01.07.2020)
Published in Cell death and differentiation (01.07.2020)
Get full text
Journal Article
Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers
Joyce, Rachel, Pascual, Rosa, Heitink, Luuk, Capaldo, Bianca D, Vaillant, François, Christie, Michael, Tsai, Minhsuang, Surgenor, Elliot, Anttila, Casey J A, Rajasekhar, Pradeep, Jackling, Felicity C, Trussart, Marie, Milevskiy, Michael J G, Song, Xiaoyu, Li, Mengbo, Teh, Charis E, Gray, Daniel H D, Smyth, Gordon K, Chen, Yunshun, Lindeman, Geoffrey J, Visvader, Jane E
Published in Nature cell biology (01.01.2024)
Published in Nature cell biology (01.01.2024)
Get full text
Journal Article
Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor-Positive Breast Cancer
Whittle, James R, Vaillant, François, Surgenor, Elliot, Policheni, Antonia N, Giner, Göknur, Capaldo, Bianca D, Chen, Huei-Rong, Liu, He K, Dekkers, Johanna F, Sachs, Norman, Clevers, Hans, Fellowes, Andrew, Green, Thomas, Xu, Huiling, Fox, Stephen B, Herold, Marco J, Smyth, Gordon K, Gray, Daniel H D, Visvader, Jane E, Lindeman, Geoffrey J
Published in Clinical cancer research (01.08.2020)
Published in Clinical cancer research (01.08.2020)
Get full text
Journal Article