Highly Potent, Anthracycline-based Antibody-Drug Conjugates Generated by Enzymatic, Site-specific Conjugation
Stefan, Nikolas, Gébleux, Rémy, Waldmeier, Lorenz, Hell, Tamara, Escher, Marie, Wolter, Fabian I, Grawunder, Ulf, Beerli, Roger R
Published in Molecular cancer therapeutics (01.05.2017)
Published in Molecular cancer therapeutics (01.05.2017)
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A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer
D'Amico, Lucia, Menzel, Ulrike, Prummer, Michael, Müller, Philipp, Buchi, Mélanie, Kashyap, Abhishek, Haessler, Ulrike, Yermanos, Alexander, Gébleux, Rémy, Briendl, Manfred, Hell, Tamara, Wolter, Fabian I, Beerli, Roger R, Truxova, Iva, Radek, Špíšek, Vlajnic, Tatjana, Grawunder, Ulf, Reddy, Sai, Zippelius, Alfred
Published in Journal for immunotherapy of cancer (21.01.2019)
Published in Journal for immunotherapy of cancer (21.01.2019)
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Novel Antibody Drug Conjugates Targeting Tumor-Associated Receptor Tyrosine Kinase ROR2 by Functional Screening of Fully Human Antibody Libraries Using Transpo-mAb Display on Progenitor B Cells
Hellmann, Ina, Waldmeier, Lorenz, Bannwarth-Escher, Marie-Christine, Maslova, Kseniya, Wolter, Fabian I, Grawunder, Ulf, Beerli, Roger R
Published in Frontiers in immunology (02.11.2018)
Published in Frontiers in immunology (02.11.2018)
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Generation of an artificial human B cell line test system using Transpo-mAbTM technology to evaluate the therapeutic efficacy of novel antigen-specific fusion proteins
Klose, Diana, Woitok, Mira, Niesen, Judith, Beerli, Roger R, Grawunder, Ulf, Fischer, Rainer, Barth, Stefan, Fendel, Rolf, Nachreiner, Thomas
Published in PloS one (01.07.2017)
Published in PloS one (01.07.2017)
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Retrocyte Display® technology: Generation and screening of a high diversity cellular antibody library
Breous-Nystrom, Ekaterina, Schultze, Kornelia, Meier, Marco, Flueck, Lukas, Holzer, Christina, Boll, Melanie, Seibert, Volker, Schuster, Andrea, Blanusa, Milan, Schaefer, Verena, Grawunder, Ulf, Martin-Parras, Luis, van Dijk, Marc A.
Published in Methods (San Diego, Calif.) (01.01.2014)
Published in Methods (San Diego, Calif.) (01.01.2014)
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The nonhomologous DNA end joining pathway is important for chromosome stability in primary fibroblasts
Karanjawala, Zarir E., Grawunder, Ulf, Hsieh, Chih-Lin, Lieber, Michael R.
Published in Current biology (16.12.1999)
Published in Current biology (16.12.1999)
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Abstract LB-197: NBE-002, an anthracycline-based immune-stimulatory antibody drug conjugate (iADC) targeting ROR1 for the treatment of triple-negative breast cancer
Beerli, Roger R., Waldmeier, Lorenz, Gébleux, Rémy, Pretto, Francesca, Grawunder, Ulf
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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NBE-002: A novel anthracycline-based antibody-drug conjugate (ADC) targeting ROR1 for the treatment of advanced solid tumors—A phase 1/2 clinical trial
Tolcher, Anthony W., Meric-Bernstam, Funda, McKean, Meredith, Beerli, Roger R, Waldmeier, Lorenz, Gebleux, Rémy, Hellmann, Ina, Chrom, Pawel, Grawunder, Ulf
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Mining Naïve Rabbit Antibody Repertoires by Phage Display for Monoclonal Antibodies of Therapeutic Utility
Peng, Haiyong, Nerreter, Thomas, Chang, Jing, Qi, Junpeng, Li, Xiuling, Karunadharma, Pabalu, Martinez, Gustavo J., Fallahi, Mohammad, Soden, Jo, Freeth, Jim, Beerli, Roger R., Grawunder, Ulf, Hudecek, Michael, Rader, Christoph
Published in Journal of molecular biology (15.09.2017)
Published in Journal of molecular biology (15.09.2017)
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Abstract 1541: Evaluation of ROR1 targeted antibody drug conjugate in ROR1 positive leukemia
Hu, Eileen, Do, Priscilla, Mani, Rajeswaran, Frissora, Frank, Pearson, Rebecca, Lozanski, Gerard, Peng, Haiyong, Waldmeier, Lorenz, Beerli, Roger, Rader, Christoph, Grawunder, Ulf, Byrd, John, Muthusamy, Natarajan
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Characterization of the housekeeping sortase from the human pathogen Propionibacterium acnes : first investigation of a class F sortase
Di Girolamo, Salvatore, Puorger, Chasper, Castiglione, Mara, Vogel, Maren, Gébleux, Rémy, Briendl, Manfred, Hell, Tamara, Beerli, Roger R, Grawunder, Ulf, Lipps, Georg
Published in Biochemical journal (28.02.2019)
Published in Biochemical journal (28.02.2019)
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