Evolutionary conservation of long non-coding RNAs; sequence, structure, function
Johnsson, Per, Lipovich, Leonard, Grandér, Dan, Morris, Kevin V.
Published in Biochimica et biophysica acta (01.03.2014)
Published in Biochimica et biophysica acta (01.03.2014)
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Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies
Herold, Nikolas, Rudd, Sean G, Ljungblad, Linda, Sanjiv, Kumar, Myrberg, Ida Hed, Paulin, Cynthia B J, Heshmati, Yaser, Hagenkort, Anna, Kutzner, Juliane, Page, Brent D G, Calderón-Montaño, José M, Loseva, Olga, Jemth, Ann-Sofie, Bulli, Lorenzo, Axelsson, Hanna, Tesi, Bianca, Valerie, Nicholas C K, Höglund, Andreas, Bladh, Julia, Wiita, Elisée, Sundin, Mikael, Uhlin, Michael, Rassidakis, Georgios, Heyman, Mats, Tamm, Katja Pokrovskaja, Warpman-Berglund, Ulrika, Walfridsson, Julian, Lehmann, Sören, Grandér, Dan, Lundbäck, Thomas, Kogner, Per, Henter, Jan-Inge, Helleday, Thomas, Schaller, Torsten
Published in Nature medicine (01.02.2017)
Published in Nature medicine (01.02.2017)
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The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for notch signaling
MALYUKOVA, Alena, DOHDA, Takeaki, VON DER LEHR, Natalie, AKHONDI, Shahab, CORCORAN, Martin, HEYMAN, Mats, SPRUCK, Charles, GRANDER, Dan, LENDAHL, Urban, SANGFELT, Olle
Published in Cancer research (Chicago, Ill.) (15.06.2007)
Published in Cancer research (Chicago, Ill.) (15.06.2007)
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Journal Article
PTENP1-AS contributes to BRAF inhibitor resistance and is associated with adverse clinical outcome in stage III melanoma
Vidarsdottir, Linda, Azimi, Alireza, Das, Ishani, Sigvaldadottir, Ingibjorg, Suryo Rahmanto, Aldwin, Petri, Andreas, Kauppinen, Sakari, Ingvar, Christian, Jönsson, Göran, Olsson, Håkan, Frostvik Stolt, Marianne, Tuominen, Rainer, Sangfelt, Olle, Pokrovskaja Tamm, Katja, Hansson, Johan, Grandér, Dan, Egyházi Brage, Suzanne, Johnsson, Per
Published in Scientific reports (26.05.2021)
Published in Scientific reports (26.05.2021)
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ClusterSignificance: a bioconductor package facilitating statistical analysis of class cluster separations in dimensionality reduced data
Serviss, Jason T, Gådin, Jesper R, Eriksson, Per, Folkersen, Lasse, Grandér, Dan
Published in Bioinformatics (Oxford, England) (01.10.2017)
Published in Bioinformatics (Oxford, England) (01.10.2017)
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Journal Article
FBXW7/hCDC4 is a general tumor suppressor in human cancer
AKHOONDI, Shahab, DAHUI SUN, MUELLER-HOLZNER, Elisabeth, CORCORAN, Martin, DAGNELL, Markus, SEPIDEH ZABIHI NEJAD, BABAK NOORI NAYER, MOHAMMAD REZA ZALI, HANSSON, Johan, EGYHAZI, Susanne, PETERSSON, Fredrik, SANGFELT, Per, VON DER LEHR, Natalie, NORDGREN, Hans, GRANDER, Dan, REED, Steven I, WIDSCHWENDTER, Martin, SANGFELT, Olle, SPRUCK, Charles, APOSTOLIDOU, Sophia, KLOTZ, Kathleen, MALJUKOVA, Alena, CEPEDA, Diana, FIEGL, Heidi, DOFOU, Dimitra, MARTH, Christian
Published in Cancer research (Chicago, Ill.) (01.10.2007)
Published in Cancer research (Chicago, Ill.) (01.10.2007)
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Journal Article
The Mutational Landscape in Pediatric Acute Lymphoblastic Leukemia Deciphered by Whole Genome Sequencing
Lindqvist, Carl Mårten, Nordlund, Jessica, Ekman, Diana, Johansson, Anna, Moghadam, Behrooz Torabi, Raine, Amanda, Övernäs, Elin, Dahlberg, Johan, Wahlberg, Per, Henriksson, Niklas, Abrahamsson, Jonas, Frost, Britt-Marie, Grandér, Dan, Heyman, Mats, Larsson, Rolf, Palle, Josefine, Söderhäll, Stefan, Forestier, Erik, Lönnerholm, Gudmar, Syvänen, Ann-Christine, Berglund, Eva C.
Published in Human mutation (01.01.2015)
Published in Human mutation (01.01.2015)
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Journal Article
Pseudogenes: a novel source of trans-acting antisense RNAs
Johnsson, Per, Morris, Kevin V, Grandér, Dan
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2014)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2014)
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Journal Article
RNAi prodrugs targeting Plk1 induce specific gene silencing in primary cells from pediatric T-acute lymphoblastic leukemia patients
Kolosenko, Iryna, Edsbäcker, Elin, Björklund, Ann-Charlotte, Hamil, Alexander S., Goroshchuk, Oksana, Grandér, Dan, Dowdy, Steven F., Palm-Apergi, Caroline
Published in Journal of controlled release (10.09.2017)
Published in Journal of controlled release (10.09.2017)
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Journal Article
A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells
Johnsson, Per, Ackley, Amanda, Vidarsdottir, Linda, Lui, Weng-Onn, Corcoran, Martin, Grandér, Dan, Morris, Kevin V
Published in Nature structural & molecular biology (01.04.2013)
Published in Nature structural & molecular biology (01.04.2013)
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Journal Article
Deep targeted sequencing in pediatric acute lymphoblastic leukemia unveils distinct mutational patterns between genetic subtypes and novel relapse-associated genes
Lindqvist, C Mårten, Lundmark, Anders, Nordlund, Jessica, Freyhult, Eva, Ekman, Diana, Carlsson Almlöf, Jonas, Raine, Amanda, Övernäs, Elin, Abrahamsson, Jonas, Frost, Britt-Marie, Grandér, Dan, Heyman, Mats, Palle, Josefine, Forestier, Erik, Lönnerholm, Gudmar, Berglund, Eva C, Syvänen, Ann-Christine
Published in Oncotarget (2016)
Published in Oncotarget (2016)
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MicroRNA-9 regulates the expression of peroxisome proliferator-activated receptor δ in human monocytes during the inflammatory response
THULIN, PETRA, WEI, TIANLING, WERNGREN, OLIVERA, CHEUNG, LOUISA, FISHER, RACHEL M, GRANDÉR, DAN, CORCORAN, MARTIN, EHRENBORG, EWA
Published in International journal of molecular medicine (01.05.2013)
Published in International journal of molecular medicine (01.05.2013)
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Journal Article
Autophagy as the main means of cytotoxicity by glucocorticoids in hematological malignancies
Grandér, Dan, Kharaziha, Pedram, Laane, Edward, Pokrovskaja, Katja, Panaretakis, Theoharis
Published in Autophagy (16.11.2009)
Published in Autophagy (16.11.2009)
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Journal Article
Identification of novel small molecules that inhibit STAT3-dependent transcription and function
Kolosenko, Iryna, Yu, Yasmin, Busker, Sander, Dyczynski, Matheus, Liu, Jianping, Haraldsson, Martin, Palm Apergi, Caroline, Helleday, Thomas, Tamm, Katja Pokrovskaja, Page, Brent D G, Grander, Dan
Published in PloS one (21.06.2017)
Published in PloS one (21.06.2017)
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Inactivation of FBXW7/hCDC4-β expression by promoter hypermethylation is associated with favorable prognosis in primary breast cancer
Akhoondi, Shahab, Lindström, Linda, Widschwendter, Martin, Corcoran, Martin, Bergh, Jonas, Spruck, Charles, Grandér, Dan, Sangfelt, Olle
Published in Breast cancer research : BCR (01.01.2010)
Published in Breast cancer research : BCR (01.01.2010)
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Journal Article
Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway
Arabi, Azadeh, Ullah, Karim, Branca, Rui M.M., Johansson, Johan, Bandarra, Daniel, Haneklaus, Moritz, Fu, Jing, Ariës, Ingrid, Nilsson, Peter, Den Boer, Monique L., Pokrovskaja, Katja, Grandér, Dan, Xiao, Gutian, Rocha, Sonia, Lehtiö, Janne, Sangfelt, Olle
Published in Nature communications (2012)
Published in Nature communications (2012)
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Journal Article
Notch signaling induces SKP2 expression and promotes reduction of p27Kip1 in T-cell acute lymphoblastic leukemia cell lines
Dohda, Takeaki, Maljukova, Aljona, Liu, Lining, Heyman, Mats, Grandér, Dan, Brodin, David, Sangfelt, Olle, Lendahl, Urban
Published in Experimental cell research (15.08.2007)
Published in Experimental cell research (15.08.2007)
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Mechanisms of interferon-alpha induced apoptosis in malignant cells
THYRELL, Lena, ERICKSON, Sven, ZHIVOTOVSKY, Boris, POKROVSKAJA, Katja, SANGFELT, Olle, CASTRO, Juan, EINHORN, Stefan, GRANDER, Dan
Published in Oncogene (14.02.2002)
Published in Oncogene (14.02.2002)
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