Intramolecular Base-Free Catalytic Wittig Reaction: Synthesis of Benzoxepinones
Grandane, Aiga, Longwitz, Lars, Roolf, Catrin, Spannenberg, Anke, Murua Escobar, Hugo, Junghanss, Christian, Suna, Edgars, Werner, Thomas
Published in Journal of organic chemistry (01.02.2019)
Published in Journal of organic chemistry (01.02.2019)
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Journal Article
Facile synthesis of coumarin bioisosteres—1,2-benzoxathiine 2,2-dioxides
Grandane, Aiga, Belyakov, Sergey, Trapencieris, Peteris, Zalubovskis, Raivis
Published in Tetrahedron (08.07.2012)
Published in Tetrahedron (08.07.2012)
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Journal Article
Long-Chain Acylcarnitines Decrease the Phosphorylation of the Insulin Receptor at Tyr1151 Through a PTP1B-Dependent Mechanism
Vilks, Karlis, Videja, Melita, Makrecka-Kuka, Marina, Katkevics, Martins, Sevostjanovs, Eduards, Grandane, Aiga, Dambrova, Maija, Liepinsh, Edgars
Published in International journal of molecular sciences (16.06.2021)
Published in International journal of molecular sciences (16.06.2021)
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Journal Article
Heart-Type Fatty Acid Binding Protein Binds Long-Chain Acylcarnitines and Protects against Lipotoxicity
Zelencova-Gopejenko, Diana, Videja, Melita, Grandane, Aiga, Pudnika-Okinčica, Linda, Sipola, Anda, Vilks, Karlis, Dambrova, Maija, Jaudzems, Kristaps, Liepinsh, Edgars
Published in International journal of molecular sciences (01.03.2023)
Published in International journal of molecular sciences (01.03.2023)
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Journal Article
Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII
Grandāne, Aiga, Nocentini, Alessio, Domračeva, Ilona, Žalubovskis, Raivis, Supuran, Claudiu T.
Published in European journal of medicinal chemistry (15.08.2020)
Published in European journal of medicinal chemistry (15.08.2020)
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Journal Article
Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase
Krasavin, Mikhail, Žalubovskis, Raivis, Grandāne, Aiga, Domračeva, Ilona, Zhmurov, Petr, Supuran, Claudiu T.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Journal Article
Base-Free Catalytic Wittig-/Cross-Coupling Reaction Sequence as Short Synthetic Strategy for the Preparation of Highly Functionalized Arylbenzoxepinones
Pudnika, Linda, Domraceva, Ilona, Werner, Thomas, Zalubovskis, Raivis, Grandane, Aiga
Published in Synthesis (Stuttgart) (01.10.2021)
Published in Synthesis (Stuttgart) (01.10.2021)
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Journal Article
Sulfocounnarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases
Tars, Kaspars, Vullo, Daniela, Kazaks, Andris, Leitans, Janis, Lends, Alons, Grandane, Aiga, Zalubovskis, Raivis, Scozzafava, Andrea, Supuran, Claudiu T.
Published in Journal of medicinal chemistry (10.01.2013)
Published in Journal of medicinal chemistry (10.01.2013)
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Journal Article
Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases
Tars, Kaspars, Vullo, Daniela, Kazaks, Andris, Leitans, Janis, Lends, Alons, Grandane, Aiga, Zalubovskis, Raivis, Scozzafava, Andrea, Supuran, Claudiu T
Published in Journal of medicinal chemistry (10.01.2013)
Published in Journal of medicinal chemistry (10.01.2013)
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Journal Article
6‑Substituted Sulfocoumarins Are Selective Carbonic Anhdydrase IX and XII Inhibitors with Significant Cytotoxicity against Colorectal Cancer Cells
Grandane, Aiga, Tanc, Muhammet, Di Cesare Mannelli, Lorenzo, Carta, Fabrizio, Ghelardini, Carla, Žalubovskis, Raivis, Supuran, Claudiu T
Published in Journal of medicinal chemistry (14.05.2015)
Published in Journal of medicinal chemistry (14.05.2015)
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Journal Article
Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII
Grandane, Aiga, Tanc, Muhammet, Zalubovskis, Raivis, Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry (01.03.2014)
Published in Bioorganic & medicinal chemistry (01.03.2014)
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Journal Article
Binding versus Enzymatic Processing of ε‑Trimethyllysine Dioxygenase Substrate Analogues
Zelencova-Gopejenko, Diana, Grandane, Aiga, Loza, Einars, Lola, Daina, Sipola, Anda, Liepinsh, Edgars, Arsenyan, Pavel, Jaudzems, Kristaps
Published in ACS medicinal chemistry letters (10.11.2022)
Published in ACS medicinal chemistry letters (10.11.2022)
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Journal Article
Facile synthesis of coumarin bioisosteresa1,2-benzoxathiine 2,2-dioxides
Grandane, Aiga, Belyakov, Sergey, Trapencieris, Peteris, Zalubovskis, Raivis
Published in Tetrahedron (08.07.2012)
Published in Tetrahedron (08.07.2012)
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Journal Article
METHOD FOR PREPARING CEDRENE DIOL
WEBER, Arne, WERNER, Thomas, STEFANOW, Vivian, GRANDANE, Aiga, LENZ, Oliver
Year of Publication 04.07.2024
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Year of Publication 04.07.2024
Patent
METHOD FOR PREPARING CEDRENE DIOL
WEBER, Arne, WERNER, Thomas, STEFANOW, Vivian, GRANDANE, Aiga, LENZ, Oliver
Year of Publication 28.02.2024
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Year of Publication 28.02.2024
Patent
DEVELOPMENT OF TRIMETHYLLYSINE HYDROXYLASE (TMLH) INHIBITORS
ARSENJANS, Pavels, DAMBROVA, Maija, ZELENCOVA-GOPEJENKO, Diana, GRANDANE, Aiga, GRINBERGA, Solveiga, LIEPINS, Edgars
Year of Publication 29.08.2024
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Year of Publication 29.08.2024
Patent