The discovery of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors
Graham, Thomas H., Shen, Hong C., Liu, Wensheng, Xiong, Yusheng, Verras, Andreas, Bleasby, Kelly, Bhatt, Urmi R., Chabin, Renee M., Chen, Dunlu, Chen, Qing, Garcia-Calvo, Margarita, Geissler, Wayne M., He, Huaibing, Lassman, Michael E., Shen, Zhu, Tong, Xinchun, Tung, Elaine C., Xie, Dan, Xu, Suoyu, Colletti, Steven L., Tata, James R., Hale, Jeffrey J., Pinto, Shirly, Shen, Dong-Ming
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
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DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates
McLaren, David G., Han, Seongah, Murphy, Beth Ann, Wilsie, Larissa, Stout, Steven J., Zhou, Haihong, Roddy, Thomas P., Gorski, Judith N., Metzger, Daniel E., Shin, Myung K., Reilly, Dermot F., Zhou, Heather H., Tadin-Strapps, Marija, Bartz, Steven R., Cumiskey, Anne-Marie, Graham, Thomas H., Shen, Dong-Ming, Akinsanya, Karen O., Previs, Stephen F., Imbriglio, Jason E., Pinto, Shirly
Published in Cell metabolism (05.06.2018)
Published in Cell metabolism (05.06.2018)
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Spectrin Tetramer Formation Is Not Required for Viable Development in Drosophila
Khanna, Mansi R., Mattie, Floyd J., Browder, Kristen C., Radyk, Megan D., Crilly, Stephanie E., Bakerink, Katelyn J., Harper, Sandra L., Speicher, David W., Thomas, Graham H.
Published in The Journal of biological chemistry (09.01.2015)
Published in The Journal of biological chemistry (09.01.2015)
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Pyrazoles as non-classical bioisosteres in prolylcarboxypeptidase (PrCP) inhibitors
Graham, Thomas H., Shu, Min, Verras, Andreas, Chen, Qing, Garcia-Calvo, Margarita, Li, Xiaohua, Lisnock, JeanMarie, Tong, Xinchun, Tung, Elaine C., Wiltsie, Judyann, Hale, Jeffrey J., Pinto, Shirly, Shen, Dong-Ming
Published in Bioorganic & medicinal chemistry letters (01.04.2014)
Published in Bioorganic & medicinal chemistry letters (01.04.2014)
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Discovery and optimization of orally active cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors
Debenham, John S., Graham, Thomas H., Verras, Andreas, Zhang, Yong, Clements, Matthew J., Kuethe, Jeffrey T., Madsen-Duggan, Christina, Liu, Wensheng, Bhatt, Urmi R., Chen, Dunlu, Chen, Qing, Garcia-Calvo, Margarita, Geissler, Wayne M., He, Huaibing, Li, Xiaohua, Lisnock, JeanMarie, Shen, Zhu, Tong, Xinchun, Tung, Elaine C., Wiltsie, Judyann, Xu, Suoyu, Hale, Jeffrey J., Pinto, Shirly, Shen, Dong-Ming
Published in Bioorganic & medicinal chemistry letters (01.12.2013)
Published in Bioorganic & medicinal chemistry letters (01.12.2013)
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A new class of prolylcarboxypeptidase inhibitors, Part 2: The aminocyclopentanes
Graham, Thomas H., Liu, Wensheng, Verras, Andreas, Reibarkh, Mikhail, Bleasby, Kelly, Bhatt, Urmi R., Chen, Qing, Garcia-Calvo, Margarita, Geissler, Wayne M., Gorski, Judith N., He, Huaibing, Lassman, Michael E., Lisnock, JeanMarie, Li, Xiaohua, Shen, Zhu, Tong, Xinchun, Tung, Elaine C., Wiltsie, Judyann, Xie, Dan, Xu, Suoyu, Xiao, Jianying, Hale, Jeffrey J., Pinto, Shirly, Shen, Dong-Ming
Published in Bioorganic & medicinal chemistry letters (15.04.2012)
Published in Bioorganic & medicinal chemistry letters (15.04.2012)
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Identifying a resistance determinant for the antimitotic natural products disorazole C1 and A1
Lazo, John S, Reese, Celeste E, Vogt, Andreas, Vollmer, Laura L, Kitchens, Carolyn A, Günther, Eckhard, Graham, Thomas H, Hopkins, Chad D, Wipf, Peter
Published in The Journal of pharmacology and experimental therapeutics (01.03.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2010)
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