Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in Synucleinopathies
Mazzulli, Joseph R., Xu, You-Hai, Sun, Ying, Knight, Adam L., McLean, Pamela J., Caldwell, Guy A., Sidransky, Ellen, Grabowski, Gregory A., Krainc, Dimitri
Published in Cell (08.07.2011)
Published in Cell (08.07.2011)
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Taliglucerase alfa: An enzyme replacement therapy using plant cell expression technology
Grabowski, Gregory A., Golembo, Myriam, Shaaltiel, Yoseph
Published in Molecular genetics and metabolism (01.05.2014)
Published in Molecular genetics and metabolism (01.05.2014)
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An unexpected player in Gaucher disease: The multiple roles of complement in disease development
Pandey, Manoj K., Grabowski, Gregory A., Köhl, Jörg
Published in Seminars in immunology (01.06.2018)
Published in Seminars in immunology (01.06.2018)
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Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease
Pandey, Manoj K, Burrow, Thomas A, Rani, Reena, Martin, Lisa J, Witte, David, Setchell, Kenneth D, Mckay, Mary A, Magnusen, Albert F, Zhang, Wujuan, Liou, Benjamin, Köhl, Jörg, Grabowski, Gregory A
Published in Nature (London) (02.03.2017)
Published in Nature (London) (02.03.2017)
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Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK
Liu, Xiaona, Chhipa, Rishi Raj, Pooya, Shabnam, Wortman, Matthew, Yachyshin, Sara, Chow, Lionel M. L., Kumar, Ashish, Zhou, Xuan, Sun, Ying, Quinn, Brian, McPherson, Christopher, Warnick, Ronald E., Kendler, Ady, Giri, Shailendra, Poels, Jeroen, Norga, Koenraad, Viollet, Benoit, Grabowski, Gregory A., Dasgupta, Biplab
Published in Proceedings of the National Academy of Sciences - PNAS (28.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (28.01.2014)
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Multi-system disorders of glycosphingolipid and ganglioside metabolism
Xu, You-Hai, Barnes, Sonya, Sun, Ying, Grabowski, Gregory A.
Published in Journal of lipid research (01.07.2010)
Published in Journal of lipid research (01.07.2010)
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An in vivo model of human small intestine using pluripotent stem cells
Watson, Carey L, Mahe, Maxime M, Múnera, Jorge, Howell, Jonathan C, Sundaram, Nambirajan, Poling, Holly M, Schweitzer, Jamie I, Vallance, Jefferson E, Mayhew, Christopher N, Sun, Ying, Grabowski, Gregory, Finkbeiner, Stacy R, Spence, Jason R, Shroyer, Noah F, Wells, James M, Helmrath, Michael A
Published in Nature medicine (01.11.2014)
Published in Nature medicine (01.11.2014)
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Properties of neurons derived from induced pluripotent stem cells of Gaucher disease type 2 patient fibroblasts: potential role in neuropathology
Sun, Ying, Florer, Jane, Mayhew, Christopher N, Jia, Zhanfeng, Zhao, Zhiying, Xu, Kui, Ran, Huimin, Liou, Benjamin, Zhang, Wujuan, Setchell, Kenneth D R, Gu, Jianguo, Grabowski, Gregory A
Published in PloS one (30.03.2015)
Published in PloS one (30.03.2015)
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CNS-accessible Inhibitor of Glucosylceramide Synthase for Substrate Reduction Therapy of Neuronopathic Gaucher Disease
Marshall, John, Sun, Ying, Bangari, Dinesh S, Budman, Eva, Park, Hyejung, Nietupski, Jennifer B, Allaire, Amy, Cromwell, Mary A, Wang, Bing, Grabowski, Gregory A, Leonard, John P, Cheng, Seng H
Published in Molecular therapy (01.06.2016)
Published in Molecular therapy (01.06.2016)
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CNS expression of glucocerebrosidase corrects α-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy
Sardi, S. Pablo, Clarke, Jennifer, Kinnecom, Cathrine, Tamsett, Thomas J., Li, Lingyun, Stanek, Lisa M., Passini, Marco A., Grabowski, Gregory A., Schlossmacher, Michael G., Sidman, Richard L., Cheng, Seng H., Shihabuddin, Lamya S.
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (19.07.2011)
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Intrinsic link between PGRN and Gba1 D409V mutation dosage in potentiating Gaucher disease
Lin, Yi, Zhao, Xiangli, Liou, Benjamin, Fannin, Venette, Zhang, Wujuan, Setchell, Kenneth D R, Wang, Xiaohong, Pan, Dao, Grabowski, Gregory A, Liu, Chuan-ju, Sun, Ying
Published in Human molecular genetics (05.08.2024)
Published in Human molecular genetics (05.08.2024)
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