Non-Peptide GPIIb/IIIa Inhibitors. 20. Centrally Constrained Thienothiophene α-Sulfonamides Are Potent, Long Acting in Vivo Inhibitors of Platelet Aggregation
Egbertson, Melissa S, Cook, Jacquelynn J, Bednar, Bohumil, Prugh, John D, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Hartman, George D, Homnick, Carl F, Holahan, Marie A, Libby, Laura A, Lynch, Joseph J, Lynch, Robert J, Sitko, Gary R, Stranieri, Maria T, Vassallo, Laura M
Published in Journal of medicinal chemistry (01.07.1999)
Published in Journal of medicinal chemistry (01.07.1999)
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Effects of inhibition of alpha-CGRP receptors on cardiac and peripheral vascular dynamics in conscious dogs with chronic heart failure
Shen, You-Tang, Mallee, John J, Handt, Laurence K, Gilberto, David B, Lynch, Jr, Joseph J, Hargreaves, Richard J, Koblan, Kenneth S, Gould, Robert J, Kane, Stefanie A
Published in Journal of cardiovascular pharmacology (01.11.2003)
Published in Journal of cardiovascular pharmacology (01.11.2003)
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Identification of Low Molecular Weight GP IIb/IIIa Antagonists That Bind Preferentially to Activated Platelets
Bednar, R A, Gaul, S L, Hamill, T G, Egbertson, M S, Shafer, J A, Hartman, G D, Gould, R J, Bednar, B
Published in The Journal of pharmacology and experimental therapeutics (01.06.1998)
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Published in The Journal of pharmacology and experimental therapeutics (01.06.1998)
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Guidelines for Modeling and Reporting Health Effects of Climate Change Mitigation Actions
Hess, Jeremy J, Ranadive, Nikhil, Boyer, Chris, Aleksandrowicz, Lukasz, Anenberg, Susan C, Aunan, Kristin, Belesova, Kristine, Bell, Michelle L, Bickersteth, Sam, Bowen, Kathryn, Burden, Marci, Campbell-Lendrum, Diarmid, Carlton, Elizabeth, Cissé, Guéladio, Cohen, Francois, Dai, Hancheng, Dangour, Alan David, Dasgupta, Purnamita, Frumkin, Howard, Gong, Peng, Gould, Robert J, Haines, Andy, Hales, Simon, Hamilton, Ian, Hasegawa, Tomoko, Hashizume, Masahiro, Honda, Yasushi, Horton, Daniel E, Karambelas, Alexandra, Kim, Ho, Kim, Satbyul Estella, Kinney, Patrick L, Kone, Inza, Knowlton, Kim, Lelieveld, Jos, Limaye, Vijay S, Liu, Qiyong, Madaniyazi, Lina, Martinez, Micaela Elvira, Mauzerall, Denise L, Milner, James, Neville, Tara, Nieuwenhuijsen, Mark, Pachauri, Shonali, Perera, Frederica, Pineo, Helen, Remais, Justin V, Saari, Rebecca K, Sampedro, Jon, Scheelbeek, Pauline, Schwartz, Joel, Shindell, Drew, Shyamsundar, Priya, Taylor, Timothy J, Tonne, Cathryn, Van Vuuren, Detlef, Wang, Can, Watts, Nicholas, West, J Jason, Wilkinson, Paul, Wood, Stephen A, Woodcock, James, Woodward, Alistair, Xie, Yang, Zhang, Ying, Ebi, Kristie L
Published in Environmental health perspectives (01.11.2020)
Published in Environmental health perspectives (01.11.2020)
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Platelet Glycoprotein IIb/IIIa Receptor Inhibitor Preserves Coronary Flow Reserve During Progressive Coronary Arteriostenosis in Swine
Shen, You-Tang, Wiedmann, Richard T, Lynch, Joseph J, Gould, Robert J
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2000)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2000)
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Tirofiban provides “platelet anesthesia” during cardiopulmonary bypass in baboons
Hiramatsu, Yuji, Gikakis, Nicolas, Anderson, Harry L., Gorman, Joseph H., Marcinkiewicz, Cezary, Gould, Robert J., Niewiarowski, Stefan, Edmunds, L.Henry
Published in The Journal of thoracic and cardiovascular surgery (1997)
Published in The Journal of thoracic and cardiovascular surgery (1997)
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EXP3174, the AII antagonist human metabolite of losartan, but not losartan nor the angiotensin-converting enzyme inhibitor captopril, prevents the development of lethal ischemic ventricular arrhythmias in a canine model of recent myocardial infarction
Lynch, Joseph J., Stump, Gary L., Wallace, Audrey A., Painter, Carla A., Thomas, Justina M., Kusma, Sandra E., Gould, Robert J., Grossman, William
Published in Journal of the American College of Cardiology (01.09.1999)
Published in Journal of the American College of Cardiology (01.09.1999)
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Nonpeptide Glycoprotein IIb/IIIa Inhibitors. 15. Antithrombotic Efficacy of L-738,167, a Long-Acting GPIIb/IIIa Antagonist, Correlates with Inhibition of Adenosine Diphosphate-Induced Platelet Aggregation but not with Bleeding Time Prolongation
Cook, J J, Sitko, G R, Holahan, M A, Stranieri, M T, Glass, J D, Askew, B C, McIntyre, C J, Claremon, D A, Baldwin, J J, Hartman, G D, Gould, R J, Lynch, Jr, J J
Published in The Journal of pharmacology and experimental therapeutics (01.05.1997)
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Published in The Journal of pharmacology and experimental therapeutics (01.05.1997)
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Non-Peptide GPIIb/IIIa Inhibitors. 20. Centrally Constrained Thienothiophene α-Sulfonamides Are Potent, Long Acting in Vivo Inhibitors of Platelet Aggregation
Egbertson, Melissa S, Cook, Jacquelynn J, Bednar, Bohumil, Prugh, John D, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Hartman, George D, Homnick, Carl F, Holahan, Marie A, Libby, Laura A, Lynch, Joseph J, Lynch, Robert J, Sitko, Gary R, Stranieri, Maria T
Published in Journal of medicinal chemistry (23.09.1999)
Published in Journal of medicinal chemistry (23.09.1999)
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Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors
Egbertson, Melissa S, Bednar, Bohumil, Askew, Ben C, Bednar, Rodney A, Brashear, Karen, Breslin, Michael J, Duggan, Mark E, Fisher, Thorsten E, Halczenko, Wasyl, Hutchinson, John H, Ihle, Nathan, Prugh, John D, Wai, John S, Gould, Robert J, Hartman, George D
Published in Bioorganic & medicinal chemistry letters (04.09.2000)
Published in Bioorganic & medicinal chemistry letters (04.09.2000)
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Nonpeptide glycoprotein IIB/IIIA inhibitors. 12. Potent and orally active centrally constrained thieno[2,3-c]pyridones
Halczenko, Wasyl, Cook, Jacquelynn J., Holahan, Marie A., Sitko, Gary R., Stranieri, Maria T., Zhang, Guixiang, Lynch, Robert J., Lynch, Joseph J., Gould, Robert J., Hartman, George D.
Published in Bioorganic & medicinal chemistry letters (19.11.1996)
Published in Bioorganic & medicinal chemistry letters (19.11.1996)
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Integrative screening approach identifies regulators of polyploidization and targets for acute megakaryocytic leukemia
Wen, Qiang, Goldenson, Benjamin, Silver, Serena J., Schenone, Monica, Dancik, Vladimir, Huang, Zan, Wang, Ling-Zhi, Lewis, Timothy, An, W. Frank, Li, Xiaoyu, Bray, Mark-Anthony, Thiollier, Clarisse, Diebold, Lauren, Gilles, Laure, Vokes, Martha S., Moore, Christopher B., Bliss-Moreau, Meghan, VerPlank, Lynn, Tolliday, Nicola J., Mishra, Rama, Vemula, Sasidhar, Shi, Jianjian, Wei, Lei, Kapur, Reuben, Lopez, Cécile K., Gerby, Bastien, Ballerini, Paola, Pflumio, Francoise, Gilliland, D. Gary, Goldberg, Liat, Birger, Yehudit, Izraeli, Shai, Gamis, Alan S., Smith, Franklin O., Woods, William G., Taub, Jeffrey, Scherer, Christina A., Bradner, James, Goh, Boon-Cher, Mercher, Thomas, Carpenter, Anne E., Gould, Robert J., Clemons, Paul A., Carr, Steven A., Root, David E., Schreiber, Stuart L., Stern, Andrew M., Crispino, John D.
Published in Cell (03.08.2012)
Published in Cell (03.08.2012)
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Effects of octyl .beta.-glucoside on insulin binding to solubilized membrane receptors
Gould, Robert J, Ginsberg, Barry H, Spector, Arthur A
Published in Biochemistry (Easton) (01.11.1981)
Published in Biochemistry (Easton) (01.11.1981)
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Effects of the prototype serotonin 5-HT sub(1B/1D) receptor agonist sumatriptan and the calcitonin gene-related peptide (CGRP) receptor antagonist CGRP sub(8-37) on myocardial reactive hyperemic response in conscious dogs
Lynch, Joseph J, Shen, You-Tang, Pittman, Tamara J, Anderson, Kenneth D, Koblan, Kenneth S, Gould, Robert J, Regan, Christopher P, Kane, Stefanie A
Published in European journal of pharmacology (25.11.2009)
Published in European journal of pharmacology (25.11.2009)
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