megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
Boissel, Sandrine, Jarjour, Jordan, Astrakhan, Alexander, Adey, Andrew, Gouble, Agnès, Duchateau, Philippe, Shendure, Jay, Stoddard, Barry L, Certo, Michael T, Baker, David, Scharenberg, Andrew M
Published in Nucleic acids research (01.02.2014)
Published in Nucleic acids research (01.02.2014)
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Endowing universal CAR T-cell with immune-evasive properties using TALEN-gene editing
Jo, Sumin, Das, Shipra, Williams, Alan, Chretien, Anne-Sophie, Pagliardini, Thomas, Le Roy, Aude, Fernandez, Jorge Postigo, Le Clerre, Diane, Jahangiri, Billal, Chion-Sotinel, Isabelle, Rozlan, Sandra, Dessez, Emilie, Gouble, Agnes, Dusséaux, Mathilde, Galetto, Roman, Duclert, Aymeric, Marcenaro, Emanuela, Devillier, Raynier, Olive, Daniel, Duchateau, Philippe, Poirot, Laurent, Valton, Julien
Published in Nature communications (30.06.2022)
Published in Nature communications (30.06.2022)
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Gene correction of a duchenne muscular dystrophy mutation by meganuclease-enhanced exon knock-in
Popplewell, Linda, Koo, Taeyoung, Leclerc, Xavier, Duclert, Aymeric, Mamchaoui, Kamel, Gouble, Agnés, Mouly, Vincent, Voit, Thomas, Pâques, Frédéric, Cédrone, Frédéric, Isman, Olga, Yáñez-Muñoz, Rafael J, Dickson, George
Published in Human gene therapy (01.07.2013)
Published in Human gene therapy (01.07.2013)
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143 Mesothelin (MSLN) targeting allogeneic CAR T cells engineered to overcome tumor immunosuppressive microenvironment
Schiffer-Mannioui, Cecile, Leduc, Sophie, Chion-Sotinel, Isabelle, Clerre, Diane le, Guyot, Valérie, Rotondi, Marco, Galetto, Roman, Gouble, Agnès
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Journal Article
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells
Garate, Zita, Quintana-Bustamante, Oscar, Crane, Ana M., Olivier, Emmanuel, Poirot, Laurent, Galetto, Roman, Kosinski, Penelope, Hill, Collin, Kung, Charles, Agirre, Xabi, Orman, Israel, Cerrato, Laura, Alberquilla, Omaira, Rodriguez-Fornes, Fatima, Fusaki, Noemi, Garcia-Sanchez, Felix, Maia, Tabita M., Ribeiro, Maria L., Sevilla, Julian, Prosper, Felipe, Jin, Shengfang, Mountford, Joanne, Guenechea, Guillermo, Gouble, Agnes, Bueren, Juan A., Davis, Brian R., Segovia, Jose C.
Published in Stem cell reports (08.12.2015)
Published in Stem cell reports (08.12.2015)
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Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies
Poirot, Laurent, Philip, Brian, Schiffer-Mannioui, Cécile, Le Clerre, Diane, Chion-Sotinel, Isabelle, Derniame, Sophie, Potrel, Pierrick, Bas, Cécile, Lemaire, Laetitia, Galetto, Roman, Lebuhotel, Céline, Eyquem, Justin, Cheung, Gordon Weng-Kit, Duclert, Aymeric, Gouble, Agnès, Arnould, Sylvain, Peggs, Karl, Pule, Martin, Scharenberg, Andrew M, Smith, Julianne
Published in Cancer research (Chicago, Ill.) (15.09.2015)
Published in Cancer research (Chicago, Ill.) (15.09.2015)
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Journal Article
Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells
Cai, Tianyu, Gouble, Agnès, Black, Kathryn L., Skwarska, Anna, Naqvi, Ammar S., Taylor, Deanne, Zhao, Ming, Yuan, Qi, Sugita, Mayumi, Zhang, Qi, Galetto, Roman, Filipe, Stéphanie, Cavazos, Antonio, Han, Lina, Kuruvilla, Vinitha, Ma, Helen, Weng, Connie, Liu, Chang-Gong, Liu, Xiuping, Konoplev, Sergej, Gu, Jun, Tang, Guilin, Su, Xiaoping, Al-Atrash, Gheath, Ciurea, Stefan, Neelapu, Sattva S., Lane, Andrew A., Kantarjian, Hagop, Guzman, Monica L., Pemmaraju, Naveen, Smith, Julianne, Thomas-Tikhonenko, Andrei, Konopleva, Marina
Published in Nature communications (28.04.2022)
Published in Nature communications (28.04.2022)
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Efficient in toto targeted recombination in mouse liver by meganuclease-induced double-strand break
Gouble, Agnès, Smith, Julianne, Bruneau, Sylvia, Perez, Christophe, Guyot, Valérie, Cabaniols, Jean-Pierre, Leduc, Sophie, Fiette, Laurence, Avé, Patrick, Micheau, Béatrice, Duchateau, Philippe, Pâques, Frédéric
Published in The journal of gene medicine (01.05.2006)
Published in The journal of gene medicine (01.05.2006)
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Allogeneic TCRαβ deficient CAR T-cells targeting CD123 in acute myeloid leukemia
Sugita, Mayumi, Galetto, Roman, Zong, Hongliang, Ewing-Crystal, Nathan, Trujillo-Alonso, Vicenta, Mencia-Trinchant, Nuria, Yip, Winnie, Filipe, Stephanie, Lebuhotel, Celine, Gouble, Agnès, Hassane, Duane C., Smith, Julianne, Roboz, Gail J., Guzman, Monica L.
Published in Nature communications (28.04.2022)
Published in Nature communications (28.04.2022)
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Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA
Quintana-Bustamante, Oscar, Fañanas-Baquero, Sara, Orman, Israel, Torres, Raul, Duchateau, Philippe, Poirot, Laurent, Gouble, Agnès, Bueren, Juan A, Segovia, Jose C
Published in PloS one (16.10.2019)
Published in PloS one (16.10.2019)
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Non-viral DNA delivery and TALEN editing correct the sickle cell mutation in hematopoietic stem cells
Moiani, Arianna, Letort, Gil, Lizot, Sabrina, Chalumeau, Anne, Foray, Chloe, Felix, Tristan, Le Clerre, Diane, Temburni-Blake, Sonal, Hong, Patrick, Leduc, Sophie, Pinard, Noemie, Marechal, Alan, Seclen, Eduardo, Boyne, Alex, Mayer, Louisa, Hong, Robert, Pulicani, Sylvain, Galetto, Roman, Gouble, Agnès, Cavazzana, Marina, Juillerat, Alexandre, Miccio, Annarita, Duclert, Aymeric, Duchateau, Philippe, Valton, Julien
Published in Nature communications (11.06.2024)
Published in Nature communications (11.06.2024)
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Targeted gene therapy of xeroderma pigmentosum cells using meganuclease and TALEN
Dupuy, Aurélie, Valton, Julien, Leduc, Sophie, Armier, Jacques, Galetto, Roman, Gouble, Agnès, Lebuhotel, Céline, Stary, Anne, Pâques, Frédéric, Duchateau, Philippe, Sarasin, Alain, Daboussi, Fayza
Published in PloS one (13.11.2013)
Published in PloS one (13.11.2013)
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Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases
Daboussi, Fayza, Zaslavskiy, Mikhail, Poirot, Laurent, Loperfido, Mariana, Gouble, Agnès, Guyot, Valerie, Leduc, Sophie, Galetto, Roman, Grizot, Sylvestre, Oficjalska, Danusia, Perez, Christophe, Delacôte, Fabien, Dupuy, Aurélie, Chion-Sotinel, Isabelle, Le Clerre, Diane, Lebuhotel, Céline, Danos, Olivier, Lemaire, Frédéric, Oussedik, Kahina, Cédrone, Frédéric, Epinat, Jean-Charles, Smith, Julianne, Yáñez-Muñoz, Rafael J, Dickson, George, Popplewell, Linda, Koo, Taeyoung, VandenDriessche, Thierry, Chuah, Marinee K, Duclert, Aymeric, Duchateau, Philippe, Pâques, Frédéric
Published in Nucleic acids research (01.07.2012)
Published in Nucleic acids research (01.07.2012)
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Abstract 2289: Allogenic TCRa/CS1 double knockout T-cells bearing an anti-CS1 chimeric antigen receptor: An improved immunotherapy approach for the treatment of multiple myeloma
Galetto, Roman, Chion-Sotinel, Isabelle, Gouble, Agnes, Smith, Julianne
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 2289: Allogenic TCRaCS1 double knockout T-cells bearing an anti-CS1 chimeric antigen receptor: An improved immunotherapy approach for the treatment of multiple myeloma
Galetto, Roman, Chion-Sotinel, Isabelle, Gouble, Agnes, Smith, Julianne
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 541: CLL-1 specific chimeric antigen receptor T cells (CART) as a novel AML therapy
Freitas, Antonio, Gautron, Anne-Sophie, Sugita, Mayumi, Goswami, Srinjoy, Galetto, Roman, Garton, Andrew, Smith, Julianne, Gouble, Agnes, Becker, Michael W., Roboz, Gail J., Guzman, Monica L.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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TALEN-mediated genetic inactivation of the glucocorticoid receptor in cytomegalovirus-specific T cells
Menger, Laurie, Gouble, Agnes, Marzolini, Maria A.V., Pachnio, Annette, Bergerhoff, Katharina, Henry, Jake Y., Smith, Julianne, Pule, Martin, Moss, Paul, Riddell, Stanley R., Quezada, Sergio A., Peggs, Karl S.
Published in Blood (24.12.2015)
Published in Blood (24.12.2015)
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