Identification of type 2 diabetes subgroups through topological analysis of patient similarity
Li, Li, Cheng, Wei-Yi, Glicksberg, Benjamin S, Gottesman, Omri, Tamler, Ronald, Chen, Rong, Bottinger, Erwin P, Dudley, Joel T
Published in Science translational medicine (28.10.2015)
Published in Science translational medicine (28.10.2015)
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Mutation spectrum of NOD2 reveals recessive inheritance as a main driver of Early Onset Crohn’s Disease
Horowitz, Julie E., Warner, Neil, Staples, Jeffrey, Crowley, Eileen, Gosalia, Nehal, Murchie, Ryan, Van Hout, Cristopher, Fiedler, Karoline, Welch, Gabriel, King, Alejandra Klauer, Reid, Jeffrey G., Overton, John D., Baras, Aris, Shuldiner, Alan R., Griffiths, Anne, Gottesman, Omri, Muise, Aleixo M., Gonzaga-Jauregui, Claudia
Published in Scientific reports (10.03.2021)
Published in Scientific reports (10.03.2021)
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Journal Article
Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease
Dewey, Frederick E, Gusarova, Viktoria, O’Dushlaine, Colm, Gottesman, Omri, Trejos, Jesus, Hunt, Charleen, Van Hout, Cristopher V, Habegger, Lukas, Buckler, David, Lai, Ka-Man V, Leader, Joseph B, Murray, Michael F, Ritchie, Marylyn D, Kirchner, H. Lester, Ledbetter, David H, Penn, John, Lopez, Alexander, Borecki, Ingrid B, Overton, John D, Reid, Jeffrey G, Carey, David J, Murphy, Andrew J, Yancopoulos, George D, Baras, Aris, Gromada, Jesper, Shuldiner, Alan R
Published in The New England journal of medicine (24.03.2016)
Published in The New England journal of medicine (24.03.2016)
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Journal Article
PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability
Kirby, Jacqueline C, Speltz, Peter, Rasmussen, Luke V, Basford, Melissa, Gottesman, Omri, Peissig, Peggy L, Pacheco, Jennifer A, Tromp, Gerard, Pathak, Jyotishman, Carrell, David S, Ellis, Stephen B, Lingren, Todd, Thompson, Will K, Savova, Guergana, Haines, Jonathan, Roden, Dan M, Harris, Paul A, Denny, Joshua C
Published in Journal of the American Medical Informatics Association : JAMIA (01.11.2016)
Published in Journal of the American Medical Informatics Association : JAMIA (01.11.2016)
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Journal Article
Opportunities for genomic clinical decision support interventions
Overby, Casey Lynnette, Kohane, Isaac, Kannry, Joseph L., Williams, Marc S., Starren, Justin, Bottinger, Erwin, Gottesman, Omri, Denny, Joshua C., Weng, Chunhua, Tarczy-Hornoch, Peter, Hripcsak, George
Published in Genetics in medicine (01.10.2013)
Published in Genetics in medicine (01.10.2013)
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Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects and tissue-specific enrichment of eQTLs
Below, Jennifer E., Parra, Esteban J., Gamazon, Eric R., Torres, Jason, Krithika, S., Candille, Sophie, Lu, Yingchang, Manichakul, Ani, Peralta-Romero, Jesus, Duan, Qing, Li, Yun, Morris, Andrew P., Gottesman, Omri, Bottinger, Erwin, Wang, Xin-Qun, Taylor, Kent D., Ida Chen, Y.-D., Rotter, Jerome I., Rich, Stephen S., Loos, Ruth J. F., Tang, Hua, Cox, Nancy J., Cruz, Miguel, Hanis, Craig L., Valladares-Salgado, Adan
Published in Scientific reports (19.01.2016)
Published in Scientific reports (19.01.2016)
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Rapid response to the alpha-1 adrenergic agent phenylephrine in the perioperative period is impacted by genomics and ancestry
Wenric, Stephane, Jeff, Janina M., Joseph, Thomas, Yee, Muh-Ching, Belbin, Gillian M., Owusu Obeng, Aniwaa, Ellis, Stephen B., Bottinger, Erwin P., Gottesman, Omri, Levin, Matthew A., Kenny, Eimear E.
Published in The pharmacogenomics journal (01.04.2021)
Published in The pharmacogenomics journal (01.04.2021)
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Journal Article
Genetic identification of a common collagen disease in puerto ricans via identity-by-descent mapping in a health system
Belbin, Gillian Morven, Odgis, Jacqueline, Sorokin, Elena P, Yee, Muh-Ching, Kohli, Sumita, Glicksberg, Benjamin S, Gignoux, Christopher R, Wojcik, Genevieve L, Van Vleck, Tielman, Jeff, Janina M, Linderman, Michael, Schurmann, Claudia, Ruderfer, Douglas, Cai, Xiaoqiang, Merkelson, Amanda, Justice, Anne E, Young, Kristin L, Graff, Misa, North, Kari E, Peters, Ulrike, James, Regina, Hindorff, Lucia, Kornreich, Ruth, Edelmann, Lisa, Gottesman, Omri, Stahl, Eli Ea, Cho, Judy H, Loos, Ruth Jf, Bottinger, Erwin P, Nadkarni, Girish N, Abul-Husn, Noura S, Kenny, Eimear E
Published in eLife (12.09.2017)
Published in eLife (12.09.2017)
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Journal Article
Can genetic pleiotropy replicate common clinical constellations of cardiovascular disease and risk?
Gottesman, Omri, Drill, Esther, Lotay, Vaneet, Bottinger, Erwin, Peter, Inga
Published in PloS one (28.09.2012)
Published in PloS one (28.09.2012)
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Journal Article
Genetic background of patients from a university medical center in Manhattan: implications for personalized medicine
Tayo, Bamidele O, Teil, Marie, Tong, Liping, Qin, Huaizhen, Khitrov, Gregory, Zhang, Weijia, Song, Quinbin, Gottesman, Omri, Zhu, Xiaofeng, Pereira, Alexandre C, Cooper, Richard S, Bottinger, Erwin P
Published in PloS one (04.05.2011)
Published in PloS one (04.05.2011)
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Journal Article
Genetic identification of familial hypercholesterolemia within a single U.S. health care system
Abul-Husn, Noura S., Manickam, Kandamurugu, Jones, Laney K., Wright, Eric A., Hartzel, Dustin N., Gonzaga-Jauregui, Claudia, O'Dushlaine, Colm, Leader, Joseph B., Kirchner, H. Lester, Lindbuchler, D'Andra M., Barr, Marci L., Giovanni, Monica A., Ritchie, Marylyn D., Overton, John D., Reid, Jeffrey G., Metpally, Raghu P. R., Wardeh, Amr H., Borecki, Ingrid B., Yancopoulos, George D., Baras, Aris, Shuldiner, Alan R., Gottesman, Omri, Ledbetter, David H., Carey, David J., Dewey, Frederick E., Murray, Michael F.
Published in Science (American Association for the Advancement of Science) (23.12.2016)
Published in Science (American Association for the Advancement of Science) (23.12.2016)
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Journal Article
Incorporating temporal EHR data in predictive models for risk stratification of renal function deterioration
Singh, Anima, Nadkarni, Girish, Gottesman, Omri, Ellis, Stephen B., Bottinger, Erwin P., Guttag, John V.
Published in Journal of biomedical informatics (01.02.2015)
Published in Journal of biomedical informatics (01.02.2015)
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Journal Article
Clinical and Molecular Prevalence of Lipodystrophy in an Unascertained Large Clinical Care Cohort
Gonzaga-Jauregui, Claudia, Ge, Wenzhen, Staples, Jeffrey, Van Hout, Cristopher, Yadav, Ashish, Colonie, Ryan, Leader, Joseph B, Kirchner, H Lester, Murray, Michael F, Reid, Jeffrey G, Carey, David J, Overton, John D, Shuldiner, Alan R, Gottesman, Omri, Gao, Steve, Gromada, Jesper, Baras, Aris, Altarejos, Judith
Published in Diabetes (New York, N.Y.) (01.02.2020)
Published in Diabetes (New York, N.Y.) (01.02.2020)
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Journal Article
Effect of Genetic African Ancestry on eGFR and Kidney Disease
Udler, Miriam S, Nadkarni, Girish N, Belbin, Gillian, Lotay, Vaneet, Wyatt, Christina, Gottesman, Omri, Bottinger, Erwin P, Kenny, Eimear E, Peter, Inga
Published in Journal of the American Society of Nephrology (01.07.2015)
Published in Journal of the American Society of Nephrology (01.07.2015)
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Journal Article
Apolipoprotein C3 induces inflammasome activation only in its delipidated form
Hsu, Cheng-Chieh, Shao, Baohai, Kanter, Jenny E., He, Yi, Vaisar, Tomas, Witztum, Joseph L., Snell-Bergeon, Janet, McInnes, Gregory, Bruse, Shannon, Gottesman, Omri, Mullick, Adam E., Bornfeldt, Karin E.
Published in Nature immunology (01.03.2023)
Published in Nature immunology (01.03.2023)
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Journal Article
The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future
Gottesman, Omri, Kuivaniemi, Helena, Tromp, Gerard, Faucett, W. Andrew, Li, Rongling, Manolio, Teri A., Sanderson, Saskia C., Kannry, Joseph, Zinberg, Randi, Basford, Melissa A., Brilliant, Murray, Carey, David J., Chisholm, Rex L., Chute, Christopher G., Connolly, John J., Crosslin, David, Denny, Joshua C., Gallego, Carlos J., Haines, Jonathan L., Hakonarson, Hakon, Harley, John, Jarvik, Gail P., Kohane, Isaac, Kullo, Iftikhar J., Larson, Eric B., McCarty, Catherine, Ritchie, Marylyn D., Roden, Dan M., Smith, Maureen E., Böttinger, Erwin P., Williams, Marc S.
Published in Genetics in medicine (01.10.2013)
Published in Genetics in medicine (01.10.2013)
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Journal Article
Apolipoprotein C3 induces inflammasome activation only in its de-lipidated form
Hsu, Cheng-Chieh, Shao, Baohai, Kanter, Jenny E., He, Yi, Vaisar, Tomas, Witztum, Joseph L., Snell-Bergeon, Janet, McInnes, Gregory, Bruse, Shannon, Gottesman, Omri, Mullick, Adam E., Bornfeldt, Karin E.
Published in Nature immunology (13.02.2023)
Published in Nature immunology (13.02.2023)
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