Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis–associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects
Kawakubo, Mitsuhiro, Tanaka, Miyako, Ochi, Kozue, Watanabe, Akiko, Saka-Tanaka, Marie, Kanamori, Yohei, Yoshioka, Naoki, Yamashita, Satoko, Goto, Moritaka, Itoh, Michiko, Shirakawa, Ibuki, Kanai, Sayaka, Suzuki, Hiromi, Sawada, Makoto, Ito, Ayaka, Ishigami, Masatoshi, Fujishiro, Mitsuhiro, Arima, Hiroshi, Ogawa, Yoshihiro, Suganami, Takayoshi
Published in Scientific reports (22.01.2020)
Published in Scientific reports (22.01.2020)
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Dual Regulation of Gluconeogenesis by Insulin and Glucose in the Proximal Tubules of the Kidney
Sasaki, Motohiro, Sasako, Takayoshi, Kubota, Naoto, Sakurai, Yoshitaka, Takamoto, Iseki, Kubota, Tetsuya, Inagi, Reiko, Seki, George, Goto, Moritaka, Ueki, Kohjiro, Nangaku, Masaomi, Jomori, Takahito, Kadowaki, Takashi
Published in Diabetes (New York, N.Y.) (01.09.2017)
Published in Diabetes (New York, N.Y.) (01.09.2017)
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Contribution of intestinal dipeptidyl peptidase-4 inhibition for incretin-dependent improved glucose tolerance in mice
Yamashita, Satoko, Kawakami, Yuriko, Sato, Hiroyuki, Sugitani, Sou, Goto, Moritaka, Kato, Noriaki
Published in European journal of pharmacology (15.09.2019)
Published in European journal of pharmacology (15.09.2019)
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Anagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Decreases Macrophage Infiltration and Suppresses Atherosclerosis in Aortic and Coronary Arteries in Cholesterol-fed Rabbits
Hirano, Tsutomu, Yamashita, Satoko, Takahashi, Masaki, Hashimoto, Hiroyuki, Mori, Yusaku, Goto, Moritaka
Published in Metabolism, clinical and experimental (01.06.2016)
Published in Metabolism, clinical and experimental (01.06.2016)
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Pseudo‐hyperglucagonemia was observed in pancreatectomized patients when measured by glucagon sandwich enzyme‐linked immunosorbent assay
Kobayashi, Masaki, Waki, Hironori, Nakayama, Hitomi, Miyachi, Atsushi, Mieno, Eri, Hamajima, Hitoshi, Goto, Moritaka, Yamada, Kentaro, Yamauchi, Toshimasa, Kadowaki, Takashi, Kitamura, Tadahiro
Published in Journal of diabetes investigation (01.02.2021)
Published in Journal of diabetes investigation (01.02.2021)
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Prognostic index for patients with relapsed or refractory acute myeloid leukemia who underwent hematopoietic cell transplantation: a KSGCT multicenter analysis
Tachibana, Takayoshi, Kanda, Junya, Ishizaki, Takuma, Najima, Yuho, Tanaka, Masatsugu, Doki, Noriko, Fujiwara, Shin-ichiro, Kimura, Shun-ichi, Onizuka, Makoto, Takahashi, Satoshi, Saito, Takeshi, Mori, Takehiko, Fujisawa, Shin, Sakaida, Emiko, Matsumoto, Kenji, Aotsuka, Nobuyuki, Goto, Moritaka, Watanabe, Reiko, Shono, Katsuhiro, Usuki, Kensuke, Tsukada, Nobuhiro, Kanamori, Heiwa, Kanda, Yoshinobu, Okamoto, Shinichiro
Published in Leukemia (01.11.2019)
Published in Leukemia (01.11.2019)
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Dipeptidyl peptidase 4 inhibitor anagliptin ameliorates hypercholesterolemia in hypercholesterolemic mice through inhibition of intestinal cholesterol transport
Goto, Moritaka, Furuta, Shinji, Yamashita, Satoko, Hashimoto, Hiroyuki, Yano, Wataru, Inoue, Noriyuki, Kato, Noriaki, Kaku, Kohei
Published in Journal of diabetes investigation (01.11.2018)
Published in Journal of diabetes investigation (01.11.2018)
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Mechanism of lipid‐lowering action of the dipeptidyl peptidase‐4 inhibitor, anagliptin, in low‐density lipoprotein receptor‐deficient mice
Yano, Wataru, Inoue, Noriyuki, Ito, Shiori, Itou, Takahiro, Yasumura, Misako, Yoshinaka, Yasunobu, Hagita, Sumihiko, Goto, Moritaka, Nakagawa, Takashi, Inoue, Keisuke, Tanabe, Sohei, Kaku, Kohei
Published in Journal of diabetes investigation (01.03.2017)
Published in Journal of diabetes investigation (01.03.2017)
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The alpha-glucosidase inhibitor miglitol increases hepatic CYP7A1 activity in association with altered short-chain fatty acid production in the gut of obese diabetic mice
Hamada, Yoji, Goto, Moritaka, Nishimura, Go, Nagasaki, Hiroshi, Seino, Yusuke, Kamiya, Hideki, Nakamura, Jiro
Published in Metabolism open (01.03.2020)
Published in Metabolism open (01.03.2020)
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Accurate analytical method for human plasma glucagon levels using liquid chromatography-high resolution mass spectrometry: comparison with commercially available immunoassays
Miyachi, Atsushi, Kobayashi, Masaki, Mieno, Eri, Goto, Moritaka, Furusawa, Kenichi, Inagaki, Takashi, Kitamura, Tadahiro
Published in Analytical and bioanalytical chemistry (01.10.2017)
Published in Analytical and bioanalytical chemistry (01.10.2017)
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Upacicalcet Is a Novel Secondary Hyperparathyroidism Drug that Targets the Amino Acid Binding Site of Calcium-Sensing Receptor
Sato, Hirofumi, Murakami, Sei, Horii, Yusuke, Nishimura, Go, Iwai, Ryosuke, Goto, Moritaka, Takahashi, Naoki
Published in Molecular pharmacology (01.10.2022)
Published in Molecular pharmacology (01.10.2022)
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Endothelin-1 is involved in the pathogenesis of ischemia/reperfusion liver injury by hepatic microcirculatory disturbances
Goto, M, Takei, Y, Kawano, S, Nagano, K, Tsuji, S, Masuda, E, Nishimura, Y, Okumura, S, Kashiwagi, T, Fusamoto, H
Published in Hepatology (Baltimore, Md.) (01.03.1994)
Published in Hepatology (Baltimore, Md.) (01.03.1994)
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Upacicalcet, a positive allosteric modulator of the calcium-sensing receptor, prevents vascular calcification and bone disorder in a rat adenine-induced secondary hyperparathyroidism model
Sato, Hirofumi, Goto, Moritaka, Nishimura, Go, Morimoto, Nobutaka, Tokushima, Hiroki, Horii, Yusuke, Takahashi, Naoki
Published in Bone (New York, N.Y.) (01.02.2023)
Published in Bone (New York, N.Y.) (01.02.2023)
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Pharmacological profile of upacicalcet, a novel positive allosteric modulator of calcium-sensing receptor, in vitro and in vivo
Goto, Moritaka, Nishimura, Go, Sato, Hirofumi, Yamaguchi, Yu, Morimoto, Nobutaka, Hashimoto, Hiroyuki, Takahashi, Naoki
Published in European journal of pharmacology (05.10.2023)
Published in European journal of pharmacology (05.10.2023)
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Upacicalcet, a Novel Non-Peptide Calcimimetic for the Treatment of Secondary Hyperparathyroidism, Has a Low Risk of Hypocalcemia: PO0318
Nishimura, Go, Yamaguchi, Yu, Goto, Moritaka, Honda, Daisuke, Takahashi, Naoki
Published in Journal of the American Society of Nephrology (01.10.2020)
Published in Journal of the American Society of Nephrology (01.10.2020)
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Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall, and intimal hyperplasia in perimenopausal human uterine arteries
Beppu, Masashi, Obayashi, Satoshi, Aso, Takeshi, Goto, Moritaka, Azuma, Hiroshi
Published in Journal of cardiovascular pharmacology (01.02.2002)
Published in Journal of cardiovascular pharmacology (01.02.2002)
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Add-on therapy with anagliptin in Japanese patients with type-2 diabetes mellitus treated with metformin and miglitol can maintain higher concentrations of biologically active GLP-1/total GIP and a lower concentration of leptin
Osonoi, Takeshi, Saito, Miyoko, Hariya, Natsuyo, Goto, Moritaka, Mochizuki, Kazuki
Published in Peptides (New York, N.Y. : 1980) (01.12.2016)
Published in Peptides (New York, N.Y. : 1980) (01.12.2016)
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Erratum to ’Contribution of intestinal dipeptidyl peptidase-4 inhibition for incretin-dependent improved glucose tolerance in mice’ [Eur. J. Pharmacol. 859 (2019) 172521]
Yamashita, Satoko, Kawakami, Yuriko, Sato, Hiroyuki, Sugitani, Sou, Goto, Moritaka, Kato, Noriaki
Published in European journal of pharmacology (05.11.2019)
Published in European journal of pharmacology (05.11.2019)
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Dipeptidyl Peptidase 4 Inhibitors Reduce Hepatocellular Carcinoma by Activating Lymphocyte Chemotaxis in Mice
Nishina, Sohji, Yamauchi, Akira, Kawaguchi, Takumi, Kaku, Kohei, Goto, Moritaka, Sasaki, Kyo, Hara, Yuichi, Tomiyama, Yasuyuki, Kuribayashi, Futoshi, Torimura, Takuji, Hino, Keisuke
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
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Anagliptin increases insulin-induced skeletal muscle glucose uptake via an NO-dependent mechanism in mice
Sato, Hiroyuki, Kubota, Naoto, Kubota, Tetsuya, Takamoto, Iseki, Iwayama, Kaito, Tokuyama, Kumpei, Moroi, Masao, Sugi, Kaoru, Nakaya, Keizo, Goto, Moritaka, Jomori, Takahito, Kadowaki, Takashi
Published in Diabetologia (01.11.2016)
Published in Diabetologia (01.11.2016)
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