Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
GOTINK, Kristy J, BROXTERMAN, Henk J, GRIFFIOEN, Arjan W, ASSARAF, Yehuda G, PILI, Roberto, PETERS, Godefridus J, VERHEUL, Henk M. W, LABOTS, Mariette, DE HAAS, Richard R, DEKKER, Henk, HONEYWELL, Richard J, RUDEK, Michelle A, BEEREPOOT, Laurens V, MUSTERS, René J, JANSEN, Gerrit
Published in Clinical cancer research (01.12.2011)
Published in Clinical cancer research (01.12.2011)
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Journal Article
Evaluation of a tyrosine kinase peptide microarray for tyrosine kinase inhibitor therapy selection in cancer
Labots, Mariette, Gotink, Kristy J, Dekker, Henk, Azijli, Kaamar, van der Mijn, Johannes C, Huijts, Charlotte M, Piersma, Sander R, Jiménez, Connie R, Verheul, Henk M W
Published in Experimental & molecular medicine (16.12.2016)
Published in Experimental & molecular medicine (16.12.2016)
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Journal Article
Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib
Gotink, Kristy J., Rovithi, Maria, de Haas, Richard R., Honeywell, Richard J., Dekker, Henk, Poel, Dennis, Azijli, Kaamar, Peters, Godefridus J., Broxterman, Henk J., Verheul, Henk M. W.
Published in Cellular oncology (Dordrecht) (01.04.2015)
Published in Cellular oncology (Dordrecht) (01.04.2015)
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Journal Article
The Potential Role of Lysosomal Sequestration in Sunitinib Resistance of Renal Cell Cancer
Azijli, Kaamar, Gotink, Kristy J, Verheul, Henk M W
Published in Journal of kidney cancer and VHL (01.01.2015)
Published in Journal of kidney cancer and VHL (01.01.2015)
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Journal Article
Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature
Gotink, Kristy J, Broxterman, Henk J, Honeywell, Richard J, Dekker, Henk, de Haas, Richard R, Miles, Kiersten M, Adelaiye, Remi, Griffioen, Arjan W, Peters, Godefridus J, Pili, Roberto, Verheul, Henk M W
Published in Oncoscience (15.12.2014)
Published in Oncoscience (15.12.2014)
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Journal Article
Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib
Broxterman, Henk J, Gotink, Kristy J, Verheul, Henk M.W
Published in Drug resistance updates (01.08.2009)
Published in Drug resistance updates (01.08.2009)
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Journal Article
Evaluation of a tyrosine kinase peptide microarray for tyrosine kinase inhibitor therapy selection in cancer
Mariette Labots, Kristy J Gotink, Henk Dekker, Kaamar Azijli, Johannes C van der Mijn, Charlotte M Huijts, Sander R Piersma, Connie R Jiménez, Henk MW Verheul
Published in Experimental & molecular medicine (01.12.2016)
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Published in Experimental & molecular medicine (01.12.2016)
Journal Article
Abstract 1621: Short-time exposure to high concentrations of sunitinib causes tumor cell death
Rovithi, Maria, Poel, Dennis, Voortman, Jens, Labots, Mariette, Dekker, Henk, Gotink, Kristy J., Broxterman, Henk J., Verheul, Henk M.W.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Abstract 1613: In vitro acquired tumor cell resistance to sunitinib contributes to an in vivo resistant phenotype
Gotink, Kristy J., Pili, Roberto, Honeywell, Richard J., Griffioen, Arjan W., Peters, Godefridus J., Broxterman, Henk J., Verheul, Henk MW
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Abstract 3608: Measurement of kinase activity in cancer cell lines and tumor tissue using a tyrosine kinase peptide substrate array
Labots, Mariette, Gotink, Kristy J., Dekker, Henk, van der Mijn, Johannes C., Broxterman, Henk J., Rovithi, Maria N., Jiménez, Connie R., Verheul, Henk M.W.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Abstract 2852: Lysosomal sequestration of sunitinib may play a role in its resistance
Gotink, Kristy J., Broxterman, Henk J., Labots, Mariette, de Haas, Richard R., Dekker, Henk, Honeywell, Richard J., Assaraf, Yehuda G., Pili, Roberto, Peters, Godefridus J., Verheul, Henk M.W.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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