Structure–activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH
Kirubakaran, Sivapriya, Gorla, Suresh Kumar, Sharling, Lisa, Zhang, Minjia, Liu, Xiaoping, Ray, Soumya S., MacPherson, Iain S., Striepen, Boris, Hedstrom, Lizbeth, Cuny, Gregory D.
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Journal Article
Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
Gorla, Suresh Kumar, Kavitha, Mandapati, Zhang, Minjia, Chin, James En Wai, Liu, Xiaoping, Striepen, Boris, Makowska-Grzyska, Magdalena, Kim, Youngchang, Joachimiak, Andrzej, Hedstrom, Lizbeth, Cuny, Gregory D
Published in Journal of medicinal chemistry (23.05.2013)
Published in Journal of medicinal chemistry (23.05.2013)
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Validation of IMP Dehydrogenase Inhibitors in a Mouse Model of Cryptosporidiosis
SURESH KUMAR GORLA, MCNAIR, Nina N, HEDSTROM, Lizbeth, GUANGYI YANG, SONG GAO, MING HU, JALA, Venkatakrishna R, HARIBABU, Bodduluri, STRIEPEN, Boris, CUNY, Gregory D, MEAD, Jan R
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
Published in Antimicrobial Agents and Chemotherapy (01.03.2014)
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Journal Article
Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds
Makowska-Grzyska, Magdalena, Kim, Youngchang, Gorla, Suresh Kumar, Wei, Yang, Mandapati, Kavitha, Zhang, Minjia, Maltseva, Natalia, Modi, Gyan, Boshoff, Helena I, Gu, Minyi, Aldrich, Courtney, Cuny, Gregory D, Hedstrom, Lizbeth, Joachimiak, Andrzej
Published in PloS one (06.10.2015)
Published in PloS one (06.10.2015)
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Journal Article
Repurposing Cryptosporidium Inosine 5′-Monophosphate Dehydrogenase Inhibitors as Potential Antibacterial Agents
Mandapati, Kavitha, Gorla, Suresh Kumar, House, Amanda L, McKenney, Elizabeth S, Zhang, Minjia, Rao, Suraj Nagendra, Gollapalli, Deviprasad R, Mann, Barbara J, Goldberg, Joanna B, Cuny, Gregory D, Glomski, Ian J, Hedstrom, Lizbeth
Published in ACS medicinal chemistry letters (14.08.2014)
Published in ACS medicinal chemistry letters (14.08.2014)
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Journal Article
A Novel Cofactor-binding Mode in Bacterial IMP Dehydrogenases Explains Inhibitor Selectivity
Makowska-Grzyska, Magdalena, Kim, Youngchang, Maltseva, Natalia, Osipiuk, Jerzy, Gu, Minyi, Zhang, Minjia, Mandapati, Kavitha, Gollapalli, Deviprasad R., Gorla, Suresh Kumar, Hedstrom, Lizbeth, Joachimiak, Andrzej
Published in The Journal of biological chemistry (27.02.2015)
Published in The Journal of biological chemistry (27.02.2015)
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Journal Article
Selective and Potent Urea Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
Gorla, Suresh Kumar, Kavitha, Mandapati, Zhang, Minjia, Liu, Xiaoping, Sharling, Lisa, Gollapalli, Deviprasad R, Striepen, Boris, Hedstrom, Lizbeth, Cuny, Gregory D
Published in Journal of medicinal chemistry (13.09.2012)
Published in Journal of medicinal chemistry (13.09.2012)
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Journal Article
Phthalazinone inhibitors of inosine-5′-monophosphate dehydrogenase from Cryptosporidium parvum
Johnson, Corey R., Gorla, Suresh Kumar, Kavitha, Mandapati, Zhang, Minjia, Liu, Xiaoping, Striepen, Boris, Mead, Jan R., Cuny, Gregory D., Hedstrom, Lizbeth
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
Published in Bioorganic & medicinal chemistry letters (15.02.2013)
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Journal Article
The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity
MacPherson, Iain S, Kirubakaran, Sivapriya, Gorla, Suresh Kumar, Riera, Thomas V, D’Aquino, J. Alejandro, Zhang, Minjia, Cuny, Gregory D, Hedstrom, Lizbeth
Published in Journal of the American Chemical Society (03.02.2010)
Published in Journal of the American Chemical Society (03.02.2010)
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Journal Article
Benzoxazoles, Phthalazinones, and Arylurea-Based Compounds with IMP Dehydrogenase-Independent Antibacterial Activity against Francisella tularensis
Gorla, Suresh Kumar, Zhang, Yan, Rabideau, Meaghan M, Qin, Aiping, Chacko, Shibin, House, Amanda L, Johnson, Corey R, Mandapati, Kavitha, Bernstein, Hannah M, McKenney, Elizabeth S, Boshoff, Helena, Zhang, Minjia, Glomski, Ian J, Goldberg, Joanna B, Cuny, Gregory D, Mann, Barbara J, Hedstrom, Lizbeth
Published in Antimicrobial agents and chemotherapy (01.10.2017)
Published in Antimicrobial agents and chemotherapy (01.10.2017)
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Journal Article
Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity
Kim, Youngchang, Makowska-Grzyska, Magdalena, Gorla, Suresh Kumar, Gollapalli, Deviprasad R., Cuny, Gregory D., Joachimiak, Andrzej, Hedstrom, Lizbeth
Published in Acta crystallographica. Section F, Structural biology communications (01.05.2015)
Published in Acta crystallographica. Section F, Structural biology communications (01.05.2015)
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Journal Article
Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity
Kim, Youngchang, Makowska-Grzyska, Magdalena, Gorla, Suresh Kumar, Gollapalli, Deviprasad R., Cuny, Gregory D., Joachimiak, Andrzej, Hedstrom, Lizbeth
Published in Acta crystallographica. Section F, Structural biology communications (21.04.2015)
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Published in Acta crystallographica. Section F, Structural biology communications (21.04.2015)
Journal Article
Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds: e0138976
Makowska-Grzyska, Magdalena, Kim, Youngchang, Gorla, Suresh Kumar, Wei, Yang, Mandapati, Kavitha, Zhang, Minjia, Maltseva, Natalia, Modi, Gyan, Boshoff, Helena I, Gu, Minyi
Published in PloS one (01.10.2015)
Published in PloS one (01.10.2015)
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Journal Article
The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity
MacPherson, Iain S, Kirubakaran, Sivapriya, Gorla, Suresh Kumar, Riera, Thomas V, D’Aquino, J. Alejandro, Zhang, Minjia, Cuny, Gregory D, Hedstrom, Lizbeth
Published in Journal of the American Chemical Society (12.05.2010)
Published in Journal of the American Chemical Society (12.05.2010)
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Journal Article
Correction to Repurposing Cryptosporidium Inosine 5′-Monophosphate Dehydrogenase Inhibitors as Potential Antibacterial Agents
Mandapati, Kavitha, Gorla, Suresh Kumar, House, Amanda L, McKenney, Elizabeth S, Zhang, Minjia, Rao, Suraj Nagendra, Gollapalli, Deviprasad R, Mann, Barbara J, Goldberg, Joanna B, Cuny, Gregory D, Glomski, Ian J, Hedstrom, Lizbeth
Published in ACS medicinal chemistry letters (09.10.2014)
Published in ACS medicinal chemistry letters (09.10.2014)
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Journal Article
cis–trans Enantiomerism in the Diels–Alder cycloadducts of 6-arylfulvenes with maleic anhydride: resolution of the exo adducts via the N-((1S)-1-(naphth-1-yl)ethyl)imide derivatives: assignment of the absolute configurations based on the crystal structure of an imide diastereomer
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