The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration
Bone, Courtney R, Tapley, Erin C, Gorjánácz, Mátyás, Starr, Daniel A
Published in Molecular biology of the cell (15.09.2014)
Published in Molecular biology of the cell (15.09.2014)
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Mitotic lamin disassembly is triggered by lipid-mediated signaling
Mall, Moritz, Walter, Thomas, Gorjánácz, Mátyás, Davidson, Iain F, Nga Ly-Hartig, Thi Bach, Ellenberg, Jan, Mattaj, Iain W
Published in The Journal of cell biology (17.09.2012)
Published in The Journal of cell biology (17.09.2012)
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Abstract LB-123: Pulsatile inhibition of PI3K converts immune suppression by Tregs and M2-TAM to anti-tumor immune response in animal models insensitive or resistant to the monotherapies of PI3K and checkpoint inhibitors
Glaeske, Sarah, Huebner, Franziska, Anurin, Anna, Janzer, Andreas, Zitzmann-Kolbe, Sabine, Paul, Juliane, Glaeske, Katja, Berndt, Sandra, Mumberg, Dominik, Gorjanacz, Matyas, Ziegelbauer, Karl, Kreft, Bertolt, Liu, Ningshu
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Abstract 1288: Blocking tumor-associated immune suppression with BAY-218, a novel, selective aryl hydrocarbon receptor (AhR) inhibitor
Gutcher, Ilona, Kober, Christina, Roese, Lars, Roewe, Julian, Schmees, Norbert, Prinz, Florian, Gorjanacz, Matyas, Roehn, Ulrike, Bader, Benjamin, Irlbacher, Horst, Stoeckigt, Detlef, Carretero, Rafael, Sahm, Katharina, Oezen, Iris, Weinmann, Hilmar, Hartung, Ingo V., Kreft, Bertolt, Platten, Michael
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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The compartmentalized bacteria of the planctomycetes-verrucomicrobia-chlamydiae superphylum have membrane coat-like proteins
Santarella-Mellwig, Rachel, Franke, Josef, Jaedicke, Andreas, Gorjánácz, Mátyás, Bauer, Ulrike, Budd, Aidan, Mattaj, Iain W, Devos, Damien P
Published in PLoS biology (01.01.2010)
Published in PLoS biology (01.01.2010)
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Abstract 2866: BAY 3375968: An afucosylated anti-CCR8 antibody depleting activated intratumoral regulatory T cells as a cancer immunotherapy
Roider, Helge, Tseng, Su-Yi, Hoff, Sabine, Berndt, Sandra, Filarski, Katharina, Gritzan, Uwe, Stelte-Ludwig, Beatrix, Nadler, Wiebke M., Grudzinska-Goebel, Joanna, Ellinger, Philipp, Trautwein, Mark, Gorjanacz, Matyas
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Abstract 5226: Novel class of potent and selective inhibitors efface MTH1 as broad-spectrum cancer target
Ellermann, Manuel, Giese, Anja, Eheim, Ashley, Bunse, Stefanie, Neuhaus, Roland, Weiske, Jörg, Quanz, Maria, Glasauer, Andrea, Rahm, Fredrik, Viklund, Jenny, Andersson, Martin, Ginman, Tobias, Forsblom, Rickard, Lindström, Johan, Trésaugues, Lionel, Gorjanacz, Matyas
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Creation of a Novel Class of Potent and Selective MutT Homologue 1 (MTH1) Inhibitors Using Fragment-Based Screening and Structure-Based Drug Design
Rahm, Fredrik, Viklund, Jenny, Trésaugues, Lionel, Ellermann, Manuel, Giese, Anja, Ericsson, Ulrika, Forsblom, Rickard, Ginman, Tobias, Günther, Judith, Hallberg, Kenth, Lindström, Johan, Persson, Lars Boukharta, Silvander, Camilla, Talagas, Antoine, Díaz-Sáez, Laura, Fedorov, Oleg, Huber, Kilian V. M, Panagakou, Ioanna, Siejka, Paulina, Gorjánácz, Mátyás, Bauser, Marcus, Andersson, Martin
Published in Journal of medicinal chemistry (22.03.2018)
Published in Journal of medicinal chemistry (22.03.2018)
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Novel Class of Potent and Cellularly Active Inhibitors Devalidates MTH1 as Broad-Spectrum Cancer Target
Ellermann, Manuel, Eheim, Ashley, Rahm, Fredrik, Viklund, Jenny, Guenther, Judith, Andersson, Martin, Ericsson, Ulrika, Forsblom, Rickard, Ginman, Tobias, Lindström, Johan, Silvander, Camilla, Trésaugues, Lionel, Giese, Anja, Bunse, Stefanie, Neuhaus, Roland, Weiske, Jörg, Quanz, Maria, Glasauer, Andrea, Nowak-Reppel, Katrin, Bader, Benjamin, Irlbacher, Horst, Meyer, Hanna, Queisser, Nina, Bauser, Marcus, Haegebarth, Andrea, Gorjánácz, Mátyás
Published in ACS chemical biology (18.08.2017)
Published in ACS chemical biology (18.08.2017)
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Abstract 689: Identification and optimization of novel chemical matter via a structure-based approach resulting in a probe for MTH1
Bauser, Marcus, Giese, Anja, Ellermann, Manuel, Guenther, Judith, Eheim, Ashley, Bunse, Stefanie, Neuhaus, Roland, Weiske, Joerg, Quanz, Maria, Glasauer, Andrea, Nowak-Reppel, Katrin, Bader, Benjamin, Irlbacher, Horst, Meyer, Hanna, Queisser, Nina, Haegebarth, Andrea, Gorjanacz, Matyas, Tresaugues, Lionel, Ginman, Tobias, Rahm, Fredrik, Andersson, Martin, Ericsson, Ulrica, Forsblom, Rickard, Lindstroem, Johan, Silvander, Camilla, Vicklund, Jenny
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Coordination of Kinase and Phosphatase Activities by Lem4 Enables Nuclear Envelope Reassembly during Mitosis
Asencio, Claudio, Davidson, Iain F., Santarella-Mellwig, Rachel, Ly-Hartig, Thi Bach Nga, Mall, Moritz, Wallenfang, Matthew R., Mattaj, Iain W., Gorjánácz, Mátyás
Published in Cell (06.07.2012)
Published in Cell (06.07.2012)
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Abstract 4539: ATAD2 mediates DNA replication in cancer
Koo, Seong Joo, Fernandez-Montalvan, Amaury Ernesto, Holton, Simon, von Ahsen, Oliver, Badock, Volker, Vittori, Sarah, Ott, Christopher J., Bradner, James E., Gorjanacz, Matyas
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action
Fernández-Montalván, Amaury E, Berger, Markus, Kuropka, Benno, Koo, Seong Joo, Badock, Volker, Weiske, Joerg, Puetter, Vera, Holton, Simon J, Stöckigt, Detlef, ter Laak, Antonius, Centrella, Paolo A, Clark, Matthew A, Dumelin, Christoph E, Sigel, Eric A, Soutter, Holly H, Troast, Dawn M, Zhang, Ying, Cuozzo, John W, Keefe, Anthony D, Roche, Didier, Rodeschini, Vincent, Chaikuad, Apirat, Díaz-Sáez, Laura, Bennett, James M, Fedorov, Oleg, Huber, Kilian V. M, Hübner, Jan, Weinmann, Hilmar, Hartung, Ingo V, Gorjánácz, Mátyás
Published in ACS chemical biology (17.11.2017)
Published in ACS chemical biology (17.11.2017)
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Abstract 5084: Potent and isoform-selective ATAD2 bromodomain inhibitor with unprecedented chemical structure and mode of action
Fernández-Montalván, Amaury E., Berger, Markus, Kuropka, Benno, Koo, Seong Joo, Badock, Volker, Weiske, Joerg, Holton, Simon J., Chaikuad, Apirat, Díaz-Sáez, Laura, Bennett, James, Federov, Oleg, Huber, Kilian, Centrella, Paolo, Clark, Matthew A., Dumelin, Christoph E., Sigel, Eric A., Soutter, Holly S., Troast, Dawn M., Zhang, Ying, Cuozzo, John W., Keefe, Anthony D., Roche, Didier, Rodeschini, Vincent, Hübner, Jan, Weinmann, Hilmar, Hartung, Ingo V., Gorjanacz, Matyas
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Samp1 is a component of TAN lines and is required for nuclear movement
Borrego-Pinto, Joana, Jegou, Thibaud, Osorio, Daniel S, Auradé, Frederic, Gorjánácz, Mátyás, Koch, Birgit, Mattaj, Iain W, Gomes, Edgar R
Published in Journal of cell science (01.03.2012)
Published in Journal of cell science (01.03.2012)
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ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication
Koo, Seong Joo, Fernández-Montalván, Amaury E, Badock, Volker, Ott, Christopher J, Holton, Simon J, von Ahsen, Oliver, Toedling, Joern, Vittori, Sarah, Bradner, James E, Gorjánácz, Mátyás
Published in Oncotarget (25.10.2016)
Published in Oncotarget (25.10.2016)
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