Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator
Gonzalo-Asensio, Jesús, Malaga, Wladimir, Pawlik, Alexandre, Astarie-Dequeker, Catherine, Passemar, Charlotte, Moreau, Flavie, Laval, Françoise, Daffé, Mamadou, Martin, Carlos, Brosch, Roland, Guilhot, Christophe
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2014)
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Journal Article
New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages
Gonzalo-Asensio, Jesús, Pérez, Irene, Aguiló, Nacho, Uranga, Santiago, Picó, Ana, Lampreave, Carlos, Cebollada, Alberto, Otal, Isabel, Samper, Sofía, Martín, Carlos
Published in PLoS genetics (12.04.2018)
Published in PLoS genetics (12.04.2018)
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Journal Article
The PhoP-dependent ncRNA Mcr7 modulates the TAT secretion system in Mycobacterium tuberculosis
Solans, Luis, Gonzalo-Asensio, Jesús, Sala, Claudia, Benjak, Andrej, Uplekar, Swapna, Rougemont, Jacques, Guilhot, Christophe, Malaga, Wladimir, Martín, Carlos, Cole, Stewart T
Published in PLoS pathogens (01.05.2014)
Published in PLoS pathogens (01.05.2014)
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Journal Article
Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference
Mata, Elena, Farrell, Damien, Ma, Ruoyao, Uranga, Santiago, Gomez, Ana Belen, Monzon, Marta, Badiola, Juan, Anel, Alberto, Gonzalo-Asensio, Jesús, Martin, Carlos, Gordon, Stephen V, Aguilo, Nacho
Published in PLoS pathogens (21.12.2020)
Published in PLoS pathogens (21.12.2020)
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Journal Article
The Mycobacterium tuberculosis PhoPR virulence system regulates expression of the universal second messenger c-di-AMP and impacts vaccine safety and efficacy
Pérez, Irene, Campos-Pardos, Elena, Díaz, Caridad, Uranga, Santiago, Sayes, Fadel, Vicente, Francisca, Aguiló, Nacho, Brosch, Roland, Martín, Carlos, Gonzalo-Asensio, Jesús
Published in Molecular therapy. Nucleic acids (08.03.2022)
Published in Molecular therapy. Nucleic acids (08.03.2022)
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Journal Article
The MtZ Strain: Molecular Characteristics and Outbreak Investigation of the Most Successful Mycobacterium tuberculosis Strain in Aragon Using Whole-Genome Sequencing
Comín, Jessica, Madacki, Jan, Rabanaque, Isabel, Zúñiga-Antón, María, Ibarz, Daniel, Cebollada, Alberto, Viñuelas, Jesús, Torres, Luis, Sahagún, Juan, Klopp, Christophe, Gonzalo-Asensio, Jesús, Brosch, Roland, Iglesias, María-José, Samper, Sofía
Published in Frontiers in cellular and infection microbiology (24.05.2022)
Published in Frontiers in cellular and infection microbiology (24.05.2022)
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Journal Article
MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against Mycobacterium tuberculosis in Mice
Broset, Esther, Saubi, Narcís, Guitart, Núria, Aguilo, Nacho, Uranga, Santiago, Kilpeläinen, Athina, Eto, Yoshiki, Hanke, Tomáš, Gonzalo-Asensio, Jesús, Martín, Carlos, Joseph-Munné, Joan
Published in Molecular therapy. Methods & clinical development (14.06.2019)
Published in Molecular therapy. Methods & clinical development (14.06.2019)
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Journal Article
Identification of three novel antisense RNAs in the fur locus from unicellular cyanobacteria
SEVILLA, Emma, MARTIN-LUNA, Beatriz, GONZALEZ, Andres, GONZALO-ASENSIO, Jesus A, PELEATO, María Luisa, FILLAT, María F
Published in Microbiology (Society for General Microbiology) (01.12.2011)
Published in Microbiology (Society for General Microbiology) (01.12.2011)
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Journal Article
Comparative Metabolomics between Mycobacterium tuberculosis and the MTBVAC Vaccine Candidate
Díaz, Caridad, Pérez del Palacio, José, Valero-Guillén, Pedro Luis, Mena García, Patricia, Pérez, Irene, Vicente, Francisca, Martín, Carlos, Genilloud, Olga, Sánchez Pozo, Antonio, Gonzalo-Asensio, Jesús
Published in ACS infectious diseases (09.08.2019)
Published in ACS infectious diseases (09.08.2019)
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Journal Article
The Mycobacterium tuberculosis phoPR Operon Is Positively Autoregulated in the Virulent Strain H37Rv
GONZALO-ASENSIO, Jesus, SOTO, Carlos Y, ARBUES, Ainhoa, SANCHO, Javier, DEL CARMEN MENDNDEZ, Maria, GARCIA, Maria J, GICQUEL, Brigitte, MARTIN, Carlos
Published in Journal of Bacteriology (01.11.2008)
Published in Journal of Bacteriology (01.11.2008)
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Journal Article
Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis
Aguilo, Nacho, Gonzalo-Asensio, Jesus, Alvarez-Arguedas, Samuel, Marinova, Dessislava, Gomez, Ana Belen, Uranga, Santiago, Spallek, Ralf, Singh, Mahavir, Audran, Regine, Spertini, François, Martin, Carlos
Published in Nature communications (14.07.2017)
Published in Nature communications (14.07.2017)
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Journal Article
Microfluidic devices for studying bacterial taxis, drug testing and biofilm formation
Pérez‐Rodríguez, Sandra, García‐Aznar, José Manuel, Gonzalo‐Asensio, Jesús
Published in Microbial biotechnology (01.02.2022)
Published in Microbial biotechnology (01.02.2022)
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Journal Article
MTBVAC from discovery to clinical trials in tuberculosis-endemic countries
Marinova, Dessislava, Gonzalo-Asensio, Jesus, Aguilo, Nacho, Martin, Carlos
Published in Expert review of vaccines (03.06.2017)
Published in Expert review of vaccines (03.06.2017)
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Journal Article
Update on TB Vaccine Pipeline
Martin, Carlos, Aguilo, Nacho, Marinova, Dessislava, Gonzalo-Asensio, Jesus
Published in Applied sciences (01.04.2020)
Published in Applied sciences (01.04.2020)
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Journal Article
Dependency on host vitamin B12 has shaped Mycobacterium tuberculosis Complex evolution
Campos-Pardos, Elena, Uranga, Santiago, Picó, Ana, Gómez, Ana Belén, Gonzalo-Asensio, Jesús
Published in Nature communications (09.03.2024)
Published in Nature communications (09.03.2024)
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Journal Article
Live-attenuated Mycobacterium tuberculosis vaccine MTBVAC versus BCG in adults and neonates: a randomised controlled, double-blind dose-escalation trial
Tameris, Michele, Mearns, Helen, Penn-Nicholson, Adam, Gregg, Yolande, Bilek, Nicole, Mabwe, Simbarashe, Geldenhuys, Hennie, Shenje, Justin, Luabeya, Angelique Kany Kany, Murillo, Ingrid, Doce, Juana, Aguilo, Nacho, Marinova, Dessislava, Puentes, Eugenia, Rodríguez, Esteban, Gonzalo-Asensio, Jesús, Fritzell, Bernard, Thole, Jelle, Martin, Carlos, Scriba, Thomas J, Hatherill, Mark
Published in The lancet respiratory medicine (01.09.2019)
Published in The lancet respiratory medicine (01.09.2019)
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Journal Article
High content phenotypic cell-based visual screen identifies Mycobacterium tuberculosis acyltrehalose-containing glycolipids involved in phagosome remodeling
Brodin, Priscille, Poquet, Yannick, Levillain, Florence, Peguillet, Isabelle, Larrouy-Maumus, Gerald, Gilleron, Martine, Ewann, Fanny, Christophe, Thierry, Fenistein, Denis, Jang, Jichan, Jang, Mi-Seon, Park, Sei-Jin, Rauzier, Jean, Carralot, Jean-Philippe, Shrimpton, Rachel, Genovesio, Auguste, Gonzalo-Asensio, Jesus A, Puzo, Germain, Martin, Carlos, Brosch, Roland, Stewart, Graham R, Gicquel, Brigitte, Neyrolles, Olivier
Published in PLoS pathogens (01.09.2010)
Published in PLoS pathogens (01.09.2010)
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