Neuroinflammation in Murine Cirrhosis Is Dependent on the Gut Microbiome and Is Attenuated by Fecal Transplant
Liu, Runping, Kang, Jason D., Sartor, R. Balfour, Sikaroodi, Masoumeh, Fagan, Andrew, Gavis, Edith A., Zhou, Huiping, Hylemon, Phillip B., Herzog, Jeremy W., Li, Xiaojiaoyang, Lippman, Robert H., Gonzalez‐Maeso, Javier, Wade, James B., Ghosh, Siddhartha, Gurley, Emily, Gillevet, Patrick M., Bajaj, Jasmohan S.
Published in Hepatology (Baltimore, Md.) (01.02.2020)
Published in Hepatology (Baltimore, Md.) (01.02.2020)
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Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice
de la Fuente Revenga, Mario, Zhu, Bohan, Guevara, Christopher A., Naler, Lynette B., Saunders, Justin M., Zhou, Zirui, Toneatti, Rudy, Sierra, Salvador, Wolstenholme, Jennifer T., Beardsley, Patrick M., Huntley, George W., Lu, Chang, González-Maeso, Javier
Published in Cell reports (Cambridge) (19.10.2021)
Published in Cell reports (Cambridge) (19.10.2021)
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Metabotropic glutamate mGlu2 receptor is necessary for the pharmacological and behavioral effects induced by hallucinogenic 5-HT2A receptor agonists
Moreno, José L., Holloway, Terrell, Albizu, Laura, Sealfon, Stuart C., González-Maeso, Javier
Published in Neuroscience letters (15.04.2011)
Published in Neuroscience letters (15.04.2011)
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Effects of the 5-HT2A receptor antagonist volinanserin on head-twitch response and intracranial self-stimulation depression induced by different structural classes of psychedelics in rodents
Jaster, Alaina M., Elder, Harrison, Marsh, Samuel A., de la Fuente Revenga, Mario, Negus, S. Stevens, González-Maeso, Javier
Published in Psychopharmacology (01.06.2022)
Published in Psychopharmacology (01.06.2022)
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Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes
Zhang, Qiang, Ma, Sai, Liu, Zhengzhi, Zhu, Bohan, Zhou, Zirui, Li, Gaoshan, Meana, J. Javier, González-Maeso, Javier, Lu, Chang
Published in Nature communications (03.08.2023)
Published in Nature communications (03.08.2023)
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Identification of a serotonin/glutamate receptor complex implicated in psychosis
Chan, Pokman, Ang, Rosalind L, Weisstaub, Noelia V, Callado, Luis F, Sealfon, Stuart C, Okawa, Yuuya, Meana, J. Javier, Gingrich, Jay A, López-Giménez, Juan F, Zhou, Mingming, Milligan, Graeme, Yuen, Tony, Filizola, Marta, González-Maeso, Javier
Published in Nature (06.03.2008)
Published in Nature (06.03.2008)
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Chronic clozapine treatment restrains via HDAC2 the performance of mGlu2 receptor agonism in a rodent model of antipsychotic activity
de la Fuente Revenga, Mario, Ibi, Daisuke, Cuddy, Travis, Toneatti, Rudy, Kurita, Mitsumasa, Ijaz, Maryum K, Miles, Michael F, Wolstenholme, Jennifer T, González-Maeso, Javier
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2019)
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2019)
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Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs
Fribourg, Miguel, Moreno, José L., Holloway, Terrell, Provasi, Davide, Baki, Lia, Mahajan, Rahul, Park, Gyu, Adney, Scott K., Hatcher, Candice, Eltit, José M., Ruta, Jeffrey D., Albizu, Laura, Li, Zheng, Umali, Adrienne, Shim, Jihyun, Fabiato, Alexandre, MacKerell, Alexander D., Brezina, Vladimir, Sealfon, Stuart C., Filizola, Marta, González-Maeso, Javier, Logothetis, Diomedes E.
Published in Cell (23.11.2011)
Published in Cell (23.11.2011)
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Reduced alcohol preference and intake after fecal transplant in patients with alcohol use disorder is transmissible to germ-free mice
Wolstenholme, Jennifer T., Saunders, Justin M., Smith, Maren, Kang, Jason D., Hylemon, Phillip B., González-Maeso, Javier, Fagan, Andrew, Zhao, Derrick, Sikaroodi, Masoumeh, Herzog, Jeremy, Shamsaddini, Amirhossein, Peña-Rodríguez, Marcela, Su, Lianyong, Tai, Yun-Ling, Zheng, Jing, Cheng, Po-Cheng, Sartor, R. Balfour, Gillevet, Patrick M., Zhou, Huiping, Bajaj, Jasmohan S.
Published in Nature communications (19.10.2022)
Published in Nature communications (19.10.2022)
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Prenatal stress induces schizophrenia-like alterations of serotonin 2A and metabotropic glutamate 2 receptors in the adult offspring: role of maternal immune system
Holloway, Terrell, Moreno, José L, Umali, Adrienne, Rayannavar, Vinayak, Hodes, Georgia E, Russo, Scott J, González-Maeso, Javier
Published in The Journal of neuroscience (16.01.2013)
Published in The Journal of neuroscience (16.01.2013)
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HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity
Kurita, Mitsumasa, Holloway, Terrell, García-Bea, Aintzane, Kozlenkov, Alexey, Friedman, Allyson K, Moreno, José L, Heshmati, Mitra, Golden, Sam A, Kennedy, Pamela J, Takahashi, Nagahide, Dietz, David M, Mocci, Giuseppe, Gabilondo, Ane M, Hanks, James, Umali, Adrienne, Callado, Luis F, Gallitano, Amelia L, Neve, Rachael L, Shen, Li, Buxbaum, Joseph D, Han, Ming-Hu, Nestler, Eric J, Meana, J Javier, Russo, Scott J, González-Maeso, Javier
Published in Nature neuroscience (01.09.2012)
Published in Nature neuroscience (01.09.2012)
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Fully automated head-twitch detection system for the study of 5-HT2A receptor pharmacology in vivo
de la Fuente Revenga, Mario, Shin, Jong M., Vohra, Hiba Z., Hideshima, Kelsey S., Schneck, Matthew, Poklis, Justin L., González-Maeso, Javier
Published in Scientific reports (03.10.2019)
Published in Scientific reports (03.10.2019)
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Interclass GPCR heteromerization affects localization and trafficking
Toneatti, Rudy, Shin, Jong M, Shah, Urjita H, Mayer, Carl R, Saunders, Justin M, Fribourg, Miguel, Arsenovic, Paul T, Janssen, William G, Sealfon, Stuart C, López-Giménez, Juan F, Benson, Deanna L, Conway, Daniel E, González-Maeso, Javier
Published in Science signaling (20.10.2020)
Published in Science signaling (20.10.2020)
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Gut microbiota manipulation during the prepubertal period shapes behavioral abnormalities in a mouse neurodevelopmental disorder model
Saunders, Justin M., Moreno, José L., Ibi, Daisuke, Sikaroodi, Masoumeh, Kang, Dae Joong, Muñoz-Moreno, Raquel, Dalmet, Swati S., García-Sastre, Adolfo, Gillevet, Patrick M., Dozmorov, Mikhail G., Bajaj, Jasmohan S., González-Maeso, Javier
Published in Scientific reports (13.03.2020)
Published in Scientific reports (13.03.2020)
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Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function
Moreno, José L., Muguruza, Carolina, Umali, Adrienne, Mortillo, Steven, Holloway, Terrell, Pilar-Cuéllar, Fuencisla, Mocci, Giuseppe, Seto, Jeremy, Callado, Luis F., Neve, Rachael L., Milligan, Graeme, Sealfon, Stuart C., López-Giménez, Juan F., Meana, J. Javier, Benson, Deanna L., González-Maeso, Javier
Published in The Journal of biological chemistry (28.12.2012)
Published in The Journal of biological chemistry (28.12.2012)
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Psychedelic-like Properties of Quipazine and Its Structural Analogues in Mice
de la Fuente Revenga, Mario, Shah, Urjita H, Nassehi, Nima, Jaster, Alaina M, Hemanth, Prithvi, Sierra, Salvador, Dukat, Malgorzata, González-Maeso, Javier
Published in ACS chemical neuroscience (03.03.2021)
Published in ACS chemical neuroscience (03.03.2021)
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Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia
Zhu, Bohan, Ainsworth, Richard I, Wang, Zengmiao, Liu, Zhengzhi, Sierra, Salvador, Deng, Chengyu, Callado, Luis F, Meana, J Javier, Wang, Wei, Lu, Chang, González-Maeso, Javier
Published in eLife (22.04.2024)
Published in eLife (22.04.2024)
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Role of mGlu2 in the 5-HT2A receptor-dependent antipsychotic activity of clozapine in mice
Hideshima, Kelsey S., Hojati, Ashkhan, Saunders, Justin M., On, Doan M., de la Fuente Revenga, Mario, Shin, Jong M., Sánchez-González, Ana, Dunn, Cassandra M., Pais, Alexander B., Pais, Anthony C., Miles, Michael F., Wolstenholme, Jennifer T., González-Maeso, Javier
Published in Psychopharmacology (01.11.2018)
Published in Psychopharmacology (01.11.2018)
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Revised Pharmacophore Model for 5‑HT2A Receptor Antagonists Derived from the Atypical Antipsychotic Agent Risperidone
Shah, Urjita H, Gaitonde, Supriya A, Moreno, José L, Glennon, Richard A, Dukat, Małgorzata, González-Maeso, Javier
Published in ACS chemical neuroscience (15.05.2019)
Published in ACS chemical neuroscience (15.05.2019)
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