Sphingosine 1-phosphate receptor signaling
Rosen, Hugh, Gonzalez-Cabrera, Pedro J, Sanna, M Germana, Brown, Steven
Published in Annual review of biochemistry (01.01.2009)
Published in Annual review of biochemistry (01.01.2009)
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Journal Article
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo
Sanna, M Germana, Wang, Sheng-Kai, Gonzalez-Cabrera, Pedro J, Don, Anthony, Marsolais, David, Matheu, Melanie P, Wei, Sindy H, Parker, Ian, Jo, Euijung, Cheng, Wei-Chieh, Cahalan, Michael D, Wong, Chi-Huey, Rosen, Hugh
Published in Nature chemical biology (01.08.2006)
Published in Nature chemical biology (01.08.2006)
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Bitopic Sphingosine 1-Phosphate Receptor 3 (S1P3) Antagonist Rescue from Complete Heart Block: Pharmacological and Genetic Evidence for Direct S1P3 Regulation of Mouse Cardiac Conduction
Sanna, M Germana, Vincent, Kevin P, Repetto, Emanuela, Nguyen, Nhan, Brown, Steven J, Abgaryan, Lusine, Riley, Sean W, Leaf, Nora B, Cahalan, Stuart M, Kiosses, William B, Kohno, Yasushi, Brown, Joan Heller, McCulloch, Andrew D, Rosen, Hugh, Gonzalez-Cabrera, Pedro J
Published in Molecular pharmacology (01.01.2016)
Published in Molecular pharmacology (01.01.2016)
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Journal Article
Full Pharmacological Efficacy of a Novel S1P1 Agonist That Does Not Require S1P-Like Headgroup Interactions
Gonzalez-Cabrera, Pedro J, Jo, Euijung, Sanna, M Germana, Brown, Steven, Leaf, Nora, Marsolais, David, Schaeffer, Marie-Therese, Chapman, Jacqueline, Cameron, Michael, Guerrero, Miguel, Roberts, Edward, Rosen, Hugh
Published in Molecular pharmacology (01.11.2008)
Published in Molecular pharmacology (01.11.2008)
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Journal Article
Tipping the gatekeeper: S1P regulation of endothelial barrier function
Rosen, Hugh, Sanna, M. Germana, Cahalan, Stuart M, Gonzalez-Cabrera, Pedro J
Published in Trends in immunology (01.03.2007)
Published in Trends in immunology (01.03.2007)
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Journal Article
Ligand-Binding Pocket Shape Differences between Sphingosine 1-Phosphate (S1P) Receptors S1P1 and S1P3 Determine Efficiency of Chemical Probe Identification by Ultrahigh-Throughput Screening
Schürer, Stephan C, Brown, Steven J, Gonzalez-Cabrera, Pedro J, Schaeffer, Marie-Therese, Chapman, Jacqueline, Jo, Euijung, Chase, Peter, Spicer, Tim, Hodder, Peter, Rosen, Hugh
Published in ACS chemical biology (15.08.2008)
Published in ACS chemical biology (15.08.2008)
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Journal Article
S1P signaling: new therapies and opportunities
Gonzalez-Cabrera, Pedro J, Brown, Steve, Studer, Sean M, Rosen, Hugh
Published in F1000 prime reports (01.12.2014)
Published in F1000 prime reports (01.12.2014)
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Journal Article
Actions of a picomolar short-acting S1P1 agonist in S1P1-eGFP knock-in mice
Cahalan, Stuart M, Gonzalez-Cabrera, Pedro J, Sarkisyan, Gor, Nguyen, Nhan, Schaeffer, Marie-Therese, Huang, Liming, Yeager, Adam, Clemons, Bryan, Scott, Fiona, Rosen, Hugh
Published in Nature chemical biology (01.05.2011)
Published in Nature chemical biology (01.05.2011)
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Journal Article
S1P Receptor Modulators in Cell Trafficking and Therapeutics
J. Gonzalez-Cabrera, Pedro, M. Cahalan, Stuart, Ferguson, Jill, Rosen, Hugh
Published in Current immunology reviews (01.05.2012)
Published in Current immunology reviews (01.05.2012)
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Journal Article
S1P(1) receptor modulation with cyclical recovery from lymphopenia ameliorates mouse model of multiple sclerosis
Gonzalez-Cabrera, Pedro J, Cahalan, Stuart M, Nguyen, Nhan, Sarkisyan, Gor, Leaf, Nora B, Cameron, Michael D, Kago, Tomoyuki, Rosen, Hugh
Published in Molecular pharmacology (01.02.2012)
Published in Molecular pharmacology (01.02.2012)
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Journal Article
Sphingosine 1-phosphate receptor 1 (S1P(1)) upregulation and amelioration of experimental autoimmune encephalomyelitis by an S1P(1) antagonist
Cahalan, Stuart M, Gonzalez-Cabrera, Pedro J, Nguyen, Nhan, Guerrero, Miguel, Cisar, Elizabeth A George, Leaf, Nora B, Brown, Steven J, Roberts, Edward, Rosen, Hugh
Published in Molecular pharmacology (01.02.2013)
Published in Molecular pharmacology (01.02.2013)
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Journal Article
Sphingosine 1-Phosphate Receptor 1 (S1P1) Upregulation and Amelioration of Experimental Autoimmune Encephalomyelitis by an S1P1 Antagonist
Cahalan, Stuart M., Gonzalez-Cabrera, Pedro J., Nguyen, Nhan, Guerrero, Miguel, Cisar, Elizabeth A. George, Leaf, Nora B., Brown, Steven J., Roberts, Edward, Rosen, Hugh
Published in Molecular pharmacology (01.02.2013)
Published in Molecular pharmacology (01.02.2013)
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Journal Article
Real-time differential labeling of blood, interstitium, and lymphatic and single-field analysis of vasculature dynamics in vivo
Sarkisyan, Gor, Cahalan, Stuart M, Gonzalez-Cabrera, Pedro J, Leaf, Nora B, Rosen, Hugh
Published in American Journal of Physiology: Cell Physiology (15.05.2012)
Published in American Journal of Physiology: Cell Physiology (15.05.2012)
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Journal Article
The organization of the sphingosine 1-phosphate signaling system
Rosen, Hugh, Germana Sanna, M, Gonzalez-Cabrera, Pedro J, Roberts, Edward
Published in Current topics in microbiology and immunology (01.01.2014)
Published in Current topics in microbiology and immunology (01.01.2014)
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Journal Article
S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate
Jo, Euijung, Sanna, M Germana, Gonzalez-Cabrera, Pedro J, Thangada, Shobha, Tigyi, Gabor, Osborne, Daniel A, Hla, Timothy, Parrill, Abby L, Rosen, Hugh
Published in Chemistry & biology (01.06.2005)
Published in Chemistry & biology (01.06.2005)
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Journal Article
Differential Regulation of the Cell Cycle by α1-Adrenergic Receptor Subtypes
Gonzalez-Cabrera, Pedro J, Shi, Ting, Yun, June, McCune, Dan F, Rorabaugh, Boyd R, Perez, Dianne M
Published in Endocrinology (Philadelphia) (01.11.2004)
Published in Endocrinology (Philadelphia) (01.11.2004)
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Journal Article
The α1B-adrenergic receptor decreases the inotropic response in the mouse Langendorff heart model
ROSS, Sean A, RORABAUGH, Boyd R, CHALOTHOM, Dan, YUN, June, GONZALEZ-CABRERA, Pedro J, MCCUNE, Dan F, PIASCIK, Michael T, PEREZ, Dianne M
Published in Cardiovascular research (01.12.2003)
Published in Cardiovascular research (01.12.2003)
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Journal Article
Gene expression profile of neurodegeneration induced by α1B‐adrenergic receptor overactivity: NMDA/GABAA dysregulation and apoptosis
Yun, June, Gaivin, Robert J., McCune, D. F., Boongird, Attaporn, Papay, Robert S., Ying, Zhong, Gonzalez‐Cabrera, Pedro J., Najm, Imad, Perez, Dianne M.
Published in Brain (London, England : 1878) (01.12.2003)
Published in Brain (London, England : 1878) (01.12.2003)
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Journal Article
Genetic profiling of alpha 1-adrenergic receptor subtypes by oligonucleotide microarrays: coupling to interleukin-6 secretion but differences in STAT3 phosphorylation and gp-130
Gonzalez-Cabrera, Pedro J, Gaivin, Robert J, Yun, June, Ross, Sean A, Papay, Robert S, McCune, Dan F, Rorabaugh, Boyd R, Perez, Dianne M
Published in Molecular pharmacology (01.05.2003)
Published in Molecular pharmacology (01.05.2003)
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