Development of LM98, a Small‐Molecule TEAD Inhibitor Derived from Flufenamic Acid
Mélin, Léa, Abdullayev, Shuay, Fnaiche, Ahmed, Vu, Victoria, González Suárez, Narjara, Zeng, Hong, Szewczyk, Magdalena M., Li, Fengling, Senisterra, Guillermo, Allali‐Hassani, Abdellah, Chau, Irene, Dong, Aiping, Woo, Simon, Annabi, Borhane, Halabelian, Levon, LaPlante, Steven R., Vedadi, Masoud, Barsyte‐Lovejoy, Dalia, Santhakumar, Vijayaratnam, Gagnon, Alexandre
Published in ChemMedChem (06.10.2021)
Published in ChemMedChem (06.10.2021)
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Journal Article
Development of HC-258, a Covalent Acrylamide TEAD Inhibitor That Reduces Gene Expression and Cell Migration
Fnaiche, Ahmed, Chan, Hwai-Chien, Paquin, Alexis, González Suárez, Narjara, Vu, Victoria, Li, Fengling, Allali-Hassani, Abdellah, Cao, Michelle Ada, Szewczyk, Magdalena M., Bolotokova, Albina, Allemand, Frédéric, Gelin, Muriel, Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Vedadi, Masoud, Guichou, Jean-François, Annabi, Borhane, Gagnon, Alexandre
Published in ACS medicinal chemistry letters (14.12.2023)
Published in ACS medicinal chemistry letters (14.12.2023)
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Journal Article
Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings
Fnaiche, Ahmed, Mélin, Léa, Suárez, Narjara González, Paquin, Alexis, Vu, Victoria, Li, Fengling, Allali-Hassani, Abdellah, Bolotokova, Albina, Allemand, Frédéric, Gelin, Muriel, Cotelle, Philippe, Woo, Simon, LaPlante, Steven R., Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Vedadi, Masoud, Guichou, Jean-François, Annabi, Borhane, Gagnon, Alexandre
Published in Bioorganic & medicinal chemistry letters (15.10.2023)
Published in Bioorganic & medicinal chemistry letters (15.10.2023)
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Journal Article
Anti-proliferative and pro-apoptotic effects induced by simultaneous inactivation of HER1 and HER2 through endogenous polyclonal antibodies
Suárez, Narjara González, Báez, Gretchen Bergado, Rodríguez, Mabel Cruz, Pérez, Amelia Gutiérrez, García, Lisset Chao, Hernández Fernández, Diana Rosa, Pous, Judith Raymond, Ramírez, Belinda Sánchez
Published in Oncotarget (10.10.2017)
Published in Oncotarget (10.10.2017)
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Journal Article
EGCG Prevents the Onset of an Inflammatory and Cancer-Associated Adipocyte-like Phenotype in Adipose-Derived Mesenchymal Stem/Stromal Cells in Response to the Triple-Negative Breast Cancer Secretome
Gonzalez Suarez, Narjara, Fernandez-Marrero, Yuniel, Torabidastgerdooei, Sima, Annabi, Borhane
Published in Nutrients (05.03.2022)
Published in Nutrients (05.03.2022)
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Journal Article
EGCG Inhibits Adipose-Derived Mesenchymal Stem Cells Differentiation into Adipocytes and Prevents a STAT3-Mediated Paracrine Oncogenic Control of Triple-Negative Breast Cancer Cell Invasive Phenotype
Gonzalez Suarez, Narjara, Rodriguez Torres, Sahily, Ouanouki, Amira, El Cheikh-Hussein, Layal, Annabi, Borhane
Published in Molecules (Basel, Switzerland) (10.03.2021)
Published in Molecules (Basel, Switzerland) (10.03.2021)
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Journal Article
EGCG Prevents the Transcriptional Reprogramming of an Inflammatory and Immune-Suppressive Molecular Signature in Macrophage-like Differentiated Human HL60 Promyelocytic Leukemia Cells
Kassouri, Celia, Rodriguez Torres, Sahily, Gonzalez Suarez, Narjara, Duhamel, Stéphanie, Annabi, Borhane
Published in Cancers (01.10.2022)
Published in Cancers (01.10.2022)
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Journal Article
EGCG inhibits the inflammation and senescence inducing properties of MDA-MB-231 triple-negative breast cancer (TNBC) cells-derived extracellular vesicles in human adipose-derived mesenchymal stem cells
Gonzalez Suarez, Narjara, Fernandez-Marrero, Yuniel, Hébert, Mathieu P. A., Roy, Marie-Eve, Boudreau, Luc H., Annabi, Borhane
Published in Cancer cell international (13.10.2023)
Published in Cancer cell international (13.10.2023)
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Journal Article
Polyclonal antibody-induced downregulation of HER1/EGFR and HER2 surpasses the effect of combinations of specific registered antibodies
Bergado-Báez, Gretchen, Gonzalez Suarez, Narjara, García, Lisset Chao, Pérez-Martínez, Dayana, Hernández-Fernández, Diana Rosa, Fundora-Barrios, Talia, Rodríguez-Álvarez, Antonio, Díaz-Ordaz, Geidy Diana, Lindzen, Moshit, Yarden, Yosef, Sánchez-Ramírez, Belinda
Published in Frontiers in oncology (02.11.2022)
Published in Frontiers in oncology (02.11.2022)
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Journal Article
Diet-Derived Gallated Catechins Prevent TGF-β-Mediated Epithelial-Mesenchymal Transition, Cell Migration and Vasculogenic Mimicry in Chemosensitive ES-2 Ovarian Cancer Cells
Sicard, Audrey-Ann, Dao, Tiziana, Suarez, Narjara Gonzalez, Annabi, Borhane
Published in Nutrition and cancer (2021)
Published in Nutrition and cancer (2021)
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Journal Article
MT1-MMP Cooperates with TGF-β Receptor-Mediated Signaling to Trigger SNAIL and Induce Epithelial-to-Mesenchymal-like Transition in U87 Glioblastoma Cells
Djediai, Souad, Gonzalez Suarez, Narjara, El Cheikh-Hussein, Layal, Rodriguez Torres, Sahily, Gresseau, Loraine, Dhayne, Sheraz, Joly-Lopez, Zoé, Annabi, Borhane
Published in International journal of molecular sciences (30.11.2021)
Published in International journal of molecular sciences (30.11.2021)
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Journal Article
Divalent vaccine compositions and the use thereof for treating tumours
González Suárez, Narjara, Gutiérrez Pérez, Amelia, Sánchez Ramírez, Belinda, Yglesias Rivera, Arianna
Year of Publication 29.10.2021
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Year of Publication 29.10.2021
Patent
DIVALENT VACCINE COMPOSITIONS AND THE USE THEREOF FOR TREATING TUMOURS
GUTIÉRREZ PÉREZ, Amelia, YGLESIAS RIVERA, Arianna, SÁNCHEZ RAMÍREZ, Belinda, GONZÁLEZ SUÁREZ, Narjara
Year of Publication 29.09.2021
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Year of Publication 29.09.2021
Patent
NANO-PARTICLES THAT CONTAIN SYNTHETIC VARIANTS OF GM3 GANGLIOSIDE AS ADJUVANTS IN VACCINES
Fernández Molina, Luis Enrique, Mesa Pardillo, Circe, Tolón Murguía, Blanca Idelmis, González Suárez, Narjara, Pérez Martínez, Dayana, Bergado Báez, Gretchen, Junco Barranco, Jesús Arturo, Manso Vargas, Ángel Alexis, López López, Miguel Antonio, Fernández Gómez, Audry, Chao García, Lisset, Hernández Fernández, Diana Rosa, Sánchez Ramírez, Belinda, Verez Bencomo, Vicente Guillermo, Cruz Rodríguez, Mabel
Year of Publication 25.04.2024
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Year of Publication 25.04.2024
Patent
Nano-particles that contain synthetic variants of gm3 ganglioside as adjuvants in vaccines
Fernández Molina, Luis Enrique, Mesa Pardillo, Circe, Tolón Murguía, Blanca Idelmis, González Suárez, Narjara, Pérez Martínez, Dayana, Bergado Báez, Gretchen, Junco Barranco, Jesús Arturo, Manso Vargas, Ángel Alexis, López López, Miguel Antonio, Fernández Gómez, Audry, Chao García, Lisset, Hernández Fernández, Diana Rosa, Sánchez Ramírez, Belinda, Verez Bencomo, Vicente Guillermo, Cruz Rodríguez, Mabel
Year of Publication 23.02.2024
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Year of Publication 23.02.2024
Patent
Nano-particles that contain synthetic variants of GM3 ganglioside as adjuvants in vaccines
Fernández Molina, Luis Enrique, Mesa Pardillo, Circe, Tolón Murguía, Blanca Idelmis, González Suárez, Narjara, Pérez Martínez, Dayana, Bergado Báez, Gretchen, Junco Barranco, Jesús Arturo, Manso Vargas, Ángel Alexis, López López, Miguel Antonio, Fernández Gómez, Audry, Chao García, Lisset, Hernández Fernández, Diana Rosa, Sánchez Ramírez, Belinda, Verez Bencomo, Vicente Guillermo, Cruz Rodríguez, Mabel
Year of Publication 07.11.2023
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Year of Publication 07.11.2023
Patent
Abstract 2562: EGCG targeting of adipogenesis reveals a STAT3-mediated paracrine oncogenic control of triple-negative breast cancer cell invasive phenotype
Suarez, Narjara Gonzalez, Torres, Sahily Rodriguez, Annabi, Borhane
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article