Selective Intracellular Activation of a Novel Prodrug of the Human Immunodeficiency Virus Reverse Transcriptase Inhibitor Tenofovir Leads to Preferential Distribution and Accumulation in Lymphatic Tissue
LEE, William A, HE, Gong-Xin, EISENBERG, Eugene, CIHLAR, Tomas, SWAMINATHAN, Swami, MULATO, Andrew, CUNDY, Kenneth C
Published in Antimicrobial Agents and Chemotherapy (01.05.2005)
Published in Antimicrobial Agents and Chemotherapy (01.05.2005)
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Activation of 9-[(R)-2-[[(S)-[[(S)-1-(Isopropoxycarbonyl)ethyl]amino] phenoxyphosphinyl]-methoxy]propyl]adenine (GS-7340) and Other Tenofovir Phosphonoamidate Prodrugs by Human Proteases
Birkus, Gabriel, Kutty, Nilima, He, Gong-Xin, Mulato, Andrew, Lee, William, McDermott, Martin, Cihlar, Tomas
Published in Molecular pharmacology (01.07.2008)
Published in Molecular pharmacology (01.07.2008)
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In Vitro Characterization of GS-8374, a Novel Phosphonate-Containing Inhibitor of HIV-1 Protease with a Favorable Resistance Profile
CALLEBAUT, Christian, STRAY, Kirsten, MULATO, Andrew, HATADA, Marcos, PRISKICH, Tina, PARKIN, Neil, SWAMINATHAN, Swami, LEE, William, HE, Gong-Xin, LIANHONG XU, CIHLAR, Tomas, TSAI, Luong, WILLIAMS, Matt, YANG, Zheng-Yu, CANNIZZARO, Carina, LEAVITT, Stephanie A, XIAOHONG LIU, KELLY WANG, MURRAY, Bernard P
Published in Antimicrobial Agents and Chemotherapy (01.04.2011)
Published in Antimicrobial Agents and Chemotherapy (01.04.2011)
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Suppression of HIV-1 Protease Inhibitor Resistance by Phosphonate-mediated Solvent Anchoring
Cihlar, Tomas, He, Gong-Xin, Liu, Xiaohong, Chen, James M., Hatada, Marcos, Swaminathan, Swami, McDermott, Martin J., Yang, Zheng-Yu, Mulato, Andrew S., Chen, Xiaowu, Leavitt, Stephanie A., Stray, Kirsten M., Lee, William A.
Published in Journal of molecular biology (27.10.2006)
Published in Journal of molecular biology (27.10.2006)
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N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase
Mitchell, Michael L., Son, Jong Chan, Guo, Hongyan, Im, Yun-A, Cho, Eun Jung, Wang, Jianhong, Hayes, Jaclyn, Wang, Michael, Paul, Amber, Lansdon, Eric B., Chen, James M., Graupe, Doris, Rhodes, Gerry, He, Gong-Xin, Geleziunas, Romas, Xu, Lianhong, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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Rational Design of Substituted Tripyrrole Peptides that Complex with DNA by Both Selective Minor-Groove Binding and Electrostatic Interaction with the Phosphate Backbone
Bruice, Thomas C., Mei, Houng-Yau, He, Gong-Xin, Lopez, Van
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.1992)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.1992)
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The rate-limiting step in the one-electron oxidation of an alkene by oxo[meso-tetrakis(2,6-dibromophenyl)porphinato]chromium(V) is the formation of a charge-transfer complex
He, Gong Xin, Arasasingham, Ramesh D, Zhang, Guo Hua, Bruice, Thomas C
Published in Journal of the American Chemical Society (01.12.1991)
Published in Journal of the American Chemical Society (01.12.1991)
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Novel glucomannan-like polysaccharide from Lycium barbarum L. ameliorates renal fibrosis via blocking macrophage-to-myofibroblasts transition
Liu, Tian, Zhang, Yun, Wu, Ze, Zhao, Chen-jing, Dong, Xi, Gong, He-xin, Jin, Bing, Han, Miao-miao, Wu, Jin-jia, Fan, Yi-kai, Li, Nan, Xiong, Ying-xia, Zhang, Zi-qian, Dong, Zheng-qi
Published in International journal of biological macromolecules (01.10.2024)
Published in International journal of biological macromolecules (01.10.2024)
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Microgonotropens and their interactions with DNA. 2. Quantitative evaluation of equilibrium constants for 1:1 and 2:1 binding of dien-microgonotropen-a, -b, and -c as well as distamycin and Hoechst 33258 to d(GGCGCAAATTTGGCGG)/d(CCGCCAAATTTGCGCC)
Browne, KA, He, Gong-Xin, Bruice, T C
Published in Journal of the American Chemical Society (01.08.1993)
Published in Journal of the American Chemical Society (01.08.1993)
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In Vitro and in Vivo Activities of Oligodeoxynucleotide-Based Thrombin Inhibitors Containing Neutral Formacetal Linkages
He, Gong-Xin, Williams, John P, Postich, Michael J, Swaminathan, S, Shea, Regan G, Terhorst, Terry, Law, Veronica S, Mao, Cheri T, Sueoka, Cathy, Coutré, Steven, Bischofberger, Norbert
Published in Journal of medicinal chemistry (22.10.1998)
Published in Journal of medicinal chemistry (22.10.1998)
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Microgonotropens and their interactions with DNA. 1. Synthesis of the tripyrrole peptides dien-microgonotropen-a, -b, and -c and characterization of their interactions with dsDNA
He, Gong-Xin, Browne, KA, Groppe, J C, Blasko, A, Mei, Houng-Yau, Bruice, T C
Published in Journal of the American Chemical Society (01.08.1993)
Published in Journal of the American Chemical Society (01.08.1993)
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New Applications of Crown Ethers. IX. Crystal Structure of KSCN Complex of N-Heptylmonoaza-18-crown-6, and Conformational Features of the Pivot Nitrogen
He, Gong-Xin, Kikukawa, Kiyoshi, Nishiyama, Nobuaki, Ohe, Hiroshi, Matsuda, Tsutomu
Published in Bulletin of the Chemical Society of Japan (01.10.1988)
Published in Bulletin of the Chemical Society of Japan (01.10.1988)
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