GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis
Littlewood-Evans, Amanda, Sarret, Sophie, Apfel, Verena, Loesle, Perrine, Dawson, Janet, Zhang, Juan, Muller, Alban, Tigani, Bruno, Kneuer, Rainer, Patel, Saijel, Valeaux, Stephanie, Gommermann, Nina, Rubic-Schneider, Tina, Junt, Tobias, Carballido, José M
Published in The Journal of experimental medicine (22.08.2016)
Published in The Journal of experimental medicine (22.08.2016)
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Journal Article
Highly Functionalized Organomagnesium Reagents Prepared through Halogen-Metal Exchange
Knochel, Paul, Dohle, Wolfgang, Gommermann, Nina, Kneisel, Florian F, Kopp, Felix, Korn, Tobias, Sapountzis, Ioannis, Vu, Viet Anh
Published in Angewandte Chemie (International ed.) (22.09.2003)
Published in Angewandte Chemie (International ed.) (22.09.2003)
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Journal Article
Synthesis of Functionalized Nitroarylmagnesium Halides via an Iodine−Magnesium Exchange
Sapountzis, Ioannis, Dube, Henry, Lewis, Robert, Gommermann, Nina, Knochel, Paul
Published in Journal of organic chemistry (01.04.2005)
Published in Journal of organic chemistry (01.04.2005)
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Journal Article
Structural basis of species-selective antagonist binding to the succinate receptor
Haffke, Matthias, Fehlmann, Dominique, Rummel, Gabriele, Boivineau, Jacques, Duckely, Myriam, Gommermann, Nina, Cotesta, Simona, Sirockin, Finton, Freuler, Felix, Littlewood-Evans, Amanda, Kaupmann, Klemens, Jaakola, Veli-Pekka
Published in Nature (London) (01.10.2019)
Published in Nature (London) (01.10.2019)
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Journal Article
Discovery of Potent, Orally Bioavailable, Tricyclic NLRP3 Inhibitors
Velcicky, Juraj, Janser, Philipp, Gommermann, Nina, Brenneisen, Silke, Ilic, Slavica, Vangrevelinghe, Eric, Stiefl, Nikolaus, Boettcher, Andreas, Arnold, Christelle, Malinverni, Claire, Dawson, Janet, Murgasova, Renata, Desrayaud, Sandrine, Beltz, Karen, Hinniger, Alexandra, Dekker, Carien, Farady, Christopher J., Mackay, Angela
Published in Journal of medicinal chemistry (25.01.2024)
Published in Journal of medicinal chemistry (25.01.2024)
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Journal Article
Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure
Velcicky, Juraj, Wilcken, Rainer, Cotesta, Simona, Janser, Philipp, Schlapbach, Achim, Wagner, Trixie, Piechon, Philippe, Villard, Frederic, Bouhelal, Rochdi, Piller, Fabian, Harlfinger, Stephanie, Stringer, Rowan, Fehlmann, Dominique, Kaupmann, Klemens, Littlewood-Evans, Amanda, Haffke, Matthias, Gommermann, Nina
Published in Journal of medicinal chemistry (10.09.2020)
Published in Journal of medicinal chemistry (10.09.2020)
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Journal Article
Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and α‑Fluoroacrylate Containing IL-17 Inhibitors
Velcicky, Juraj, Bauer, Matthias R., Schlapbach, Achim, Lapointe, Guillaume, Meyer, Arndt, Vögtle, Markus, Blum, Ernst, Ngo, Estelle, Rolando, Catherine, Nimsgern, Pierre, Teixeira-Fouchard, Sylvie, Lehmann, Hansjoerg, Furet, Pascal, Berst, Frédéric, Schümann, Jens, Stringer, Rowan, Larger, Patrice, Schmid, Cindy, Prendergast, Catriona T., Riek, Simone, Schmutz, Patrick, Lehmann, Sylvie, Berghausen, Jörg, Scheufler, Clemens, Rondeau, Jean-Michel, Burkhart, Christoph, Knoepfel, Thomas, Gommermann, Nina
Published in Journal of medicinal chemistry (26.09.2024)
Published in Journal of medicinal chemistry (26.09.2024)
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Journal Article
NLRP3 인플라마좀 억제제
MATTES HENRI, STIEFL NIKOLAUS JOHANNES, GOMMERMANN NINA, JANSER PHILIPP, MACKAY ANGELA, FARADY CHRISTOPHER, VELCICKY JURAJ
Year of Publication 08.04.2021
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Year of Publication 08.04.2021
Patent
NLRP3 인플라마좀 억제제
MATTES HENRI, FOOKS SOLOVAY CATHERINE, VON MATT ANETTE, SMITH NICHOLA, STIEFL NIKOLAUS JOHANNES, GOMMERMANN NINA, JANSER PHILIPP, VANGREVELINGHE ERIC, MACKAY ANGELA, FARADY CHRISTOPHER, VELCICKY JURAJ
Year of Publication 21.01.2022
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Year of Publication 21.01.2022
Patent
New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck
Gommermann, Nina, Buehlmayer, Peter, von Matt, Anette, Breitenstein, Werner, Masuya, Keiichi, Pirard, Bernard, Furet, Pascal, Cowan-Jacob, Sandra W., Weckbecker, Gisbert
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
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