Antichagasic, Leishmanicidal, and Trichomonacidal Activity of 2‐Benzyl‐5‐nitroindazole‐Derived Amines
Fonseca‐Berzal, Cristina, Ibáñez‐Escribano, Alexandra, Vela, Nerea, Cumella, José, Nogal‐Ruiz, Juan José, Escario, José Antonio, da Silva, Patrícia Bernardino, Batista, Marcos Meuser, Soeiro, Maria de Nazaré C., Sifontes‐Rodríguez, Sergio, Meneses‐Marcel, Alfredo, Gómez‐Barrio, Alicia, Arán, Vicente J.
Published in ChemMedChem (20.06.2018)
Published in ChemMedChem (20.06.2018)
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Validation of a modified fluorimetric assay for the screening of trichomonacidal drugs
Escribano, Alexandra Ibáñez, Marcel, Alfredo Meneses, Tugores, Yanetsy Machado, Ruiz, Juan José Nogal, Redó, Vicente J Arán, García-Trevijano, José Antonio Escario, Barrio, Alicia Gómez
Published in Memórias do Instituto Oswaldo Cruz (01.08.2012)
Published in Memórias do Instituto Oswaldo Cruz (01.08.2012)
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Predicting antitrichomonal activity: A computational screening using atom-based bilinear indices and experimental proofs
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Published in Bioorganic & medicinal chemistry (01.10.2006)
Published in Bioorganic & medicinal chemistry (01.10.2006)
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Identification In Silico and In Vitro of Novel Trypanosomicidal Drug-Like Compounds
Castillo-Garit, Juan A., del Toro-Cortés, Oremia, Kouznetsov, Vladimir V., Puentes, Cristian Ochoa, Romero Bohórquez, Arnold R., Vega, Maria C., Rolón, Miriam, Escario, José A., Gómez-Barrio, Alicia, Marrero-Ponce, Yovani, Torrens, Francisco, Abad, Concepción
Published in Chemical biology & drug design (01.07.2012)
Published in Chemical biology & drug design (01.07.2012)
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Determination of internal transcribed spacer regions (ITS) in Trichomonas vaginalis isolates and differentiation among Trichomonas species
Ibáñez-Escribano, Alexandra, Nogal-Ruiz, Juan José, Arán, Vicente J, Escario, José Antonio, Gómez-Barrio, Alicia, Alderete, J.F
Published in Parasitology international (01.04.2014)
Published in Parasitology international (01.04.2014)
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Bond-based linear indices in QSAR: computational discovery of novel anti-trichomonal compounds
Marrero-Ponce, Yovani, Meneses-Marcel, Alfredo, Rivera-Borroto, Oscar M., García-Domenech, Ramón, De Julián-Ortiz, Jesus Vicente, Montero, Alina, Escario, José Antonio, Barrio, Alicia Gómez, Pereira, David Montero, Nogal, Juan José, Grau, Ricardo, Torrens, Francisco, Vogel, Christian, Arán, Vicente J.
Published in Journal of computer-aided molecular design (01.08.2008)
Published in Journal of computer-aided molecular design (01.08.2008)
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5-Nitroindazole-based compounds: further studies for activity optimization as anti-Trypanosoma cruzi agents
Fonseca-Berzal, Cristina, Ibáñez-Escribano, Alexandra, de Castro, Sonia, Escario, José A., Gómez-Barrio, Alicia, Arán, Vicente J.
Published in Acta tropica (01.10.2022)
Published in Acta tropica (01.10.2022)
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Synthesis and Evaluation of 1,1′-Hydrocarbylenebis(indazol-3-ols) as Potential Antimalarial Drugs
Martins Alho, Miriam, García-Sánchez, Rory N., Nogal-Ruiz, Juan José, Escario, José Antonio, Gómez-Barrio, Alicia, Martínez-Fernández, Antonio R., Arán, Vicente J.
Published in ChemMedChem (12.01.2009)
Published in ChemMedChem (12.01.2009)
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Promising hit compounds against resistant trichomoniasis: Synthesis and antiparasitic activity of 3-(ω-aminoalkoxy)-1-benzyl-5-nitroindazoles
Ibáñez-Escribano, Alexandra, Reviriego, Felipe, Vela, Nerea, Fonseca-Berzal, Cristina, Nogal-Ruiz, Juan José, Arán, Vicente J., Escario, José Antonio, Gómez-Barrio, Alicia
Published in Bioorganic & medicinal chemistry letters (01.04.2021)
Published in Bioorganic & medicinal chemistry letters (01.04.2021)
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Synthesis and Biophysical and Biological Studies of N‑Phenylbenzamide Derivatives Targeting Kinetoplastid Parasites
Nué-Martinez, J. Jonathan, Cisneros, David, Moreno-Blázquez, María del Valle, Fonseca-Berzal, Cristina, Manzano, José Ignacio, Kraeutler, Damien, Ungogo, Marzuq A., Aloraini, Maha A., Elati, Hamza A. A., Ibáñez-Escribano, Alexandra, Lagartera, Laura, Herraiz, Tomás, Gamarro, Francisco, de Koning, Harry P., Gómez-Barrio, Alicia, Dardonville, Christophe
Published in Journal of medicinal chemistry (12.10.2023)
Published in Journal of medicinal chemistry (12.10.2023)
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Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles
Fonseca-Berzal, Cristina, Ibáñez-Escribano, Alexandra, Reviriego, Felipe, Cumella, José, Morales, Paula, Jagerovic, Nadine, Nogal-Ruiz, Juan José, Escario, José Antonio, da Silva, Patricia Bernardino, Soeiro, Maria de Nazaré C., Gómez-Barrio, Alicia, Arán, Vicente J.
Published in European journal of medicinal chemistry (10.06.2016)
Published in European journal of medicinal chemistry (10.06.2016)
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Thio- and selenosemicarbazones as antiprotozoal agents against Trypanosoma cruzi and Trichomonas vaginalis
Ibáñez-Escribano, Alexandra, Fonseca-Berzal, Cristina, Martínez-Montiel, Mónica, Álvarez-Márquez, Manuel, Gómez-Núñez, María, Lacueva-Arnedo, Manuel, Espinosa-Buitrago, Teresa, Martín-Pérez, Tania, Escario, José Antonio, Merino-Montiel, Penélope, Montiel-Smith, Sara, Gómez-Barrio, Alicia, López, Óscar, Fernández-Bolaños, José G
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Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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Synthesis and characterization of a pyridine-2-thiol N-oxide gold(I) complex with potent antiproliferative effect against Trypanosoma cruzi and Leishmania sp. insight into its mechanism of action
Vieites, Marisol, Smircich, Pablo, Guggeri, Lucía, Marchán, Edgar, Gómez-Barrio, Alicia, Navarro, Maribel, Garat, Beatriz, Gambino, Dinorah
Published in Journal of inorganic biochemistry (01.10.2009)
Published in Journal of inorganic biochemistry (01.10.2009)
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Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug
Vega, María Celeste, Rolón, Miriam, Montero-Torres, Alina, Fonseca-Berzal, Cristina, Escario, José Antonio, Gómez-Barrio, Alicia, Gálvez, Jorge, Marrero-Ponce, Yovani, Arán, Vicente J.
Published in European journal of medicinal chemistry (01.12.2012)
Published in European journal of medicinal chemistry (01.12.2012)
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Novel solid dispersions of benznidazole: Preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system
Fonseca-Berzal, Cristina, Palmeiro-Roldán, Ricardo, Escario, José A., Torrado, Susana, Arán, Vicente J., Torrado-Santiago, Santiago, Gómez-Barrio, Alicia
Published in Experimental parasitology (01.02.2015)
Published in Experimental parasitology (01.02.2015)
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Bond-based bilinear indices for computational discovery of novel trypanosomicidal drug-like compounds through virtual screening
Castillo-Garit, Juan Alberto, del Toro-Cortés, Oremia, Vega, Maria C., Rolón, Miriam, Rojas de Arias, Antonieta, Casañola-Martin, Gerardo M., Escario, José A., Gómez-Barrio, Alicia, Marrero-Ponce, Yovani, Torrens, Francisco, Abad, Concepción
Published in European journal of medicinal chemistry (26.05.2015)
Published in European journal of medicinal chemistry (26.05.2015)
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Selective activity of 2,4-diaryl-1,2,3,4-tetrahydroquinolines on Trypanosoma cruzi epimastigotes and amastigotes expressing β-galactosidase
Fonseca-Berzal, Cristina, Merchán Arenas, Diego R., Romero Bohórquez, Arnold R., Escario, José A., Kouznetsov, Vladimir V., Gómez-Barrio, Alicia
Published in Bioorganic & medicinal chemistry letters (01.09.2013)
Published in Bioorganic & medicinal chemistry letters (01.09.2013)
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Development of novel benznidazole formulations: Physicochemical characterization and in vivo evaluation on parasitemia reduction in Chagas disease
Palmeiro-Roldán, Ricardo, Fonseca-Berzal, Cristina, Gómez-Barrio, Alicia, Arán, Vicente J., Escario, José A., Torrado-Durán, Susana, Torrado-Santiago, Santiago
Published in International journal of pharmaceutics (10.09.2014)
Published in International journal of pharmaceutics (10.09.2014)
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