Mesothelin-Targeted Thorium-227 Conjugate (MSLN-TTC): Preclinical Evaluation of a New Targeted Alpha Therapy for Mesothelin-Positive Cancers
Hagemann, Urs B, Ellingsen, Christine, Schuhmacher, Joachim, Kristian, Alexander, Mobergslien, Anne, Cruciani, Véronique, Wickstroem, Katrine, Schatz, Christoph A, Kneip, Christoph, Golfier, Sven, Smeets, Roger, Uran, Steinar, Hennekes, Hartwig, Karlsson, Jenny, Bjerke, Roger M, Ryan, Olav B, Mumberg, Dominik, Ziegelbauer, Karl, Cuthbertson, Alan S
Published in Clinical cancer research (01.08.2019)
Published in Clinical cancer research (01.08.2019)
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Journal Article
Preclinical Antitumor Efficacy of BAY 1129980-a Novel Auristatin-Based Anti-C4.4A (LYPD3) Antibody-Drug Conjugate for the Treatment of Non-Small Cell Lung Cancer
Willuda, Jörg, Linden, Lars, Lerchen, Hans-Georg, Kopitz, Charlotte, Stelte-Ludwig, Beatrix, Pena, Carol, Lange, Claudia, Golfier, Sven, Kneip, Christoph, Carrigan, Patricia E, Mclean, Kirk, Schuhmacher, Joachim, von Ahsen, Oliver, Müller, Jörg, Dittmer, Frank, Beier, Rudolf, El Sheikh, Sherif, Tebbe, Jan, Leder, Gabriele, Apeler, Heiner, Jautelat, Rolf, Ziegelbauer, Karl, Kreft, Bertolt
Published in Molecular cancer therapeutics (01.05.2017)
Published in Molecular cancer therapeutics (01.05.2017)
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Journal Article
T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction
Pinkert, Jessica, Boehm, Hans-Henning, Trautwein, Mark, Doecke, Wolf-Dietrich, Wessel, Florian, Ge, Yingzi, Gutierrez, Eva Maria, Carretero, Rafael, Freiberg, Christoph, Gritzan, Uwe, Luetke-Eversloh, Merlin, Golfier, Sven, Von Ahsen, Oliver, Volpin, Valentina, Sorrentino, Antonio, Rathinasamy, Anchana, Xydia, Maria, Lohmayer, Robert, Sax, Julian, Nur-Menevse, Ayse, Hussein, Abir, Stamova, Slava, Beckmann, Georg, Glueck, Julian Marius, Schoenfeld, Dorian, Weiske, Joerg, Zopf, Dieter, Offringa, Rienk, Kreft, Bertolt, Beckhove, Philipp, Willuda, Joerg
Published in Oncoimmunology (01.01.2022)
Published in Oncoimmunology (01.01.2022)
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Journal Article
Novel Antibody Therapeutics Targeting Mesothelin In Solid Tumors
Zhao, Xiao-Yan, Subramanyam, Babu, Sarapa, Nenad, Golfier, Sven, Dinter, Harald
Published in Clinical cancer drugs (01.10.2016)
Published in Clinical cancer drugs (01.10.2016)
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Journal Article
Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4
Golfier, Sven, Kondo, Shinichi, Schulze, Tobias, Takeuchi, Tomomi, Vassileva, Galya, Achtman, Ariel H, Gräler, Markus H, Abbondanzo, Susan J, Wiekowski, Maria, Kremmer, Elisabeth, Endo, Yasuhisa, Lira, Sergio A, Bacon, Kevin B, Lipp, Martin
Published in The FASEB journal (01.12.2010)
Published in The FASEB journal (01.12.2010)
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The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage-Inducing or Repair-Compromising Therapies in Preclinical Cancer Models
Wengner, Antje M, Siemeister, Gerhard, Lücking, Ulrich, Lefranc, Julien, Wortmann, Lars, Lienau, Philip, Bader, Benjamin, Bömer, Ulf, Moosmayer, Dieter, Eberspächer, Uwe, Golfier, Sven, Schatz, Christoph A, Baumgart, Simon J, Haendler, Bernard, Lejeune, Pascale, Schlicker, Andreas, von Nussbaum, Franz, Brands, Michael, Ziegelbauer, Karl, Mumberg, Dominik
Published in Molecular cancer therapeutics (01.01.2020)
Published in Molecular cancer therapeutics (01.01.2020)
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Journal Article
3D high-content screening for the identification of compounds that target cells in dormant tumor spheroid regions
Wenzel, Carsten, Riefke, Björn, Gründemann, Stephan, Krebs, Alice, Christian, Sven, Prinz, Florian, Osterland, Marc, Golfier, Sven, Räse, Sebastian, Ansari, Nariman, Esner, Milan, Bickle, Marc, Pampaloni, Francesco, Mattheyer, Christian, Stelzer, Ernst H., Parczyk, Karsten, Prechtl, Stefan, Steigemann, Patrick
Published in Experimental cell research (15.04.2014)
Published in Experimental cell research (15.04.2014)
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Journal Article
Anetumab ravtansine: a novel mesothelin-targeting antibody-drug conjugate cures tumors with heterogeneous target expression favored by bystander effect
Golfier, Sven, Kopitz, Charlotte, Kahnert, Antje, Heisler, Iring, Schatz, Christoph A, Stelte-Ludwig, Beatrix, Mayer-Bartschmid, Anke, Unterschemmann, Kerstin, Bruder, Sandra, Linden, Lars, Harrenga, Axel, Hauff, Peter, Scholle, Frank-Detlef, Müller-Tiemann, Beate, Kreft, Bertolt, Ziegelbauer, Karl
Published in Molecular cancer therapeutics (01.06.2014)
Published in Molecular cancer therapeutics (01.06.2014)
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Journal Article
Anetumab ravtansine inhibits tumor growth and shows additive effect in combination with targeted agents and chemotherapy in mesothelin-expressing human ovarian cancer models
Quanz, Maria, Hagemann, Urs B, Zitzmann-Kolbe, Sabine, Stelte-Ludwig, Beatrix, Golfier, Sven, Elbi, Cem, Mumberg, Dominik, Ziegelbauer, Karl, Schatz, Christoph A
Published in Oncotarget (25.09.2018)
Published in Oncotarget (25.09.2018)
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Journal Article
Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
Graham, Keith, Lienau, Philip, Bader, Benjamin, Prechtl, Stefan, Naujoks, Jan, Lesche, Ralf, Weiske, Joerg, Kuehnlenz, Julia, Brzezinka, Krzysztof, Potze, Lisette, Zanconato, Francesca, Nicke, Barbara, Montebaur, Anna, Bone, Wilhelm, Golfier, Sven, Kaulfuss, Stefan, Kopitz, Charlotte, Pilari, Sabine, Steuber, Holger, Hayat, Sikander, Kamburov, Atanas, Steffen, Andreas, Schlicker, Andreas, Buchgraber, Philipp, Braeuer, Nico, Font, Nuria Aiguabella, Heinrich, Tobias, Kuhnke, Lara, Nowak-Reppel, Katrin, Stresemann, Carlo, Steigemann, Patrick, Walter, Annette O., Blotta, Simona, Ocker, Matthias, Lakner, Ashley, von Nussbaum, Franz, Mumberg, Dominik, Eis, Knut, Piccolo, Stefano, Lange, Martin
Published in Cell chemical biology (18.07.2024)
Published in Cell chemical biology (18.07.2024)
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Journal Article
Abstract 1780: Anetumab ravtansine has single-agent activity in mesothelin-expressing human ovarian cancer models and potentiates the activity of chemotherapeutics and targeted agents
Schatz, Christoph A., Quanz, Maria, Hagemann, Urs B., Zitzmann-Kolbe, Sabine, Stelte-Ludwig, Beatrix, Golfier, Sven, Kopitz, Charlotte, Elbi, Cem, Ziegelbauer, Karl, Mumberg, Dominik
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Preclinical investigation to compare different gadolinium-based contrast agents regarding their propensity to release gadolinium in vivo and to trigger nephrogenic systemic fibrosis-like lesions
Sieber, Martin A., Lengsfeld, Philipp, Frenzel, Thomas, Golfier, Sven, Schmitt-Willich, Heribert, Siegmund, Fred, Walter, Jakob, Weinmann, Hanns-Joachim, Pietsch, Hubertus
Published in European radiology (01.10.2008)
Published in European radiology (01.10.2008)
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Journal Article
The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells
Textor, Sonja, Bossler, Felicitas, Henrich, Kai-Oliver, Gartlgruber, Moritz, Pollmann, Julia, Fiegler, Nathalie, Arnold, Annette, Westermann, Frank, Waldburger, Nina, Breuhahn, Kai, Golfier, Sven, Witzens-Harig, Mathias, Cerwenka, Adelheid
Published in Oncoimmunology (02.07.2016)
Published in Oncoimmunology (02.07.2016)
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Journal Article
Abstract 2778: Discovery and preclinical characterization of BAY 1905254 a novel immune checkpoint inhibitor for cancer immunotherapy targeting the immunoglobulin-like domain containing receptor 2 (ILDR2)
Huetter, Julia, Gritzan, Uwe, Gutcher, Ilona, Golfier, Sven, Doecke, Wolf-Dietrich, Luetke-Eversloh, Merlin Verena, Roider, Helge, Hunter, John, Pow, Andrew, Liang, Spencer, Levine, Zurit, Levy, Ofer, Vaaknin, Ilan, Kreft, Bertolt, Roese, Lars
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Abstract 836: ATR inhibitor BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride in preclinical tumor models
Wengner, Antje Margret, Siemeister, Gerhard, Luecking, Ulrich, Lefranc, Julien, Lienau, Philip, Deeg, Gesa, Lagkadinou, Eleni, Liu, Li, Golfier, Sven, Schatz, Christoph, Scholz, Arne, Nussbaum, Franz von, Brands, Michael, Mumberg, Dominik, Ziegelbauer, Karl
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 1771: BAY 1834942 is an immunotherapeutic antibody blocking the novel immune checkpoint regulator CEACAM6 (CD66c)
Willuda, Joerg, Trautwein, Mark, Pinkert, Jessica, Doecke, Wolf-Dietrich, Boehm, Hans-Henning, Wessel, Florian, Ge, Yingzi, Gutierrez, Eva Maria, Weiske, Joerg, Freiberg, Christoph, Gritzan, Uwe, Glueck, Julian, Zopf, Dieter, Golfier, Sven, Ahsen, Oliver von, Zierz, Ruprecht, Wittemer-Rump, Sabine, Apeler, Heiner, Karl, Ziegelbauer, Offringa, Rienk, Kreft, Bertolt, Philipp, Beckhove
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P
Golfier, Sven, Kondo, Shinichi, Schulze, Tobias, Takeuchi, Tomomi, Vassileva, Galya, Achtman, Ariel H, Gräler, Markus H, Abbondanzo, Susan J, Wiekowski, Maria, Kremmer, Elisabeth, Endo, Yasuhisa, Lira, Sergio A, Bacon, Kevin B, Lipp, Martin
Published in The FASEB journal (01.12.2010)
Published in The FASEB journal (01.12.2010)
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Journal Article
Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2)
Huetter, Julia, Gritzan, Uwe, Gutcher, Ilona, Doecke, Wolf-Dietrich, Luetke-Eversloh, Merlin V, Golfier, Sven, Roider, Helge G, Frisk, Anna-Lena, Hunter, John, Pow, Andrew, Drake, Andrew, Levine, Zurit, Levy, Ofer, Azulay, Meir, Barbiro, Inbal, Cojocaru, Gady, Vaknin, Ilan, Kreft, Bertolt, Roese, Lars
Published in Cancer immunology research (01.07.2020)
Published in Cancer immunology research (01.07.2020)
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Journal Article
Abstract 4584: Novel YAP1/TAZ pathway inhibitors identified through phenotypic screening with potent anti-tumor activity via blockade of GGTase-I and Rho-GTPase signaling
Graham, Keith, Lienau, Philip, Bader, Benjamin, Prechtl, Stefan, Naujoks, Jan, Lesche, Ralf, Nicke, Barbara, Bone, Wilhelm, Golfier, Sven, Brzezinka, Krzysztof, Kaulfuss, Stefan, Kopitz, Charlotte, Steuber, Holger, Braeuer, Nico, Nowak-Reppel, Katrin, Stresemann, Carlo, Steigemann, Patrick, Kuehnlenz, Julia, Potze, Lisette, Zanconato, Francesca, Montebaur, Anna, Pilari, Sabine, Hayat, Sikander, Kamburov, Atanas, Steffen, Andreas, Schlicker, Andreas, Buchgraber, Philipp, Font, Nuria Aiguabella, Heinrich, Tobias, Kuhnke, Lara, Walter, Annette O., Blotta, Simona, Ocker, Matthias, Lakner, Ashley, Mumberg, Dominik, Eis, Knut, Piccolo, Stefano, Lange, Martin
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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과다증식성 질환을 치료하는 방법에 사용하기 위한 ATR 키나제의 억제제
GOLFIER SVEN, WENGNER ANTJE MARGRET, SIEMEISTER GERHARD, HAENDLER BERNARD, SCHLICKER ANDREAS, LIU LI
Year of Publication 23.10.2019
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Year of Publication 23.10.2019
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