Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors
Goldberg, Daniel R., De Lombaert, Stéphane, Aiello, Robert, Bourassa, Patricia, Barucci, Nicole, Zhang, Qing, Paralkar, Vishwas, Stein, Adam J., Holt, Melissa, Valentine, Jim, Zavadoski, William
Published in Bioorganic & medicinal chemistry letters (01.02.2017)
Published in Bioorganic & medicinal chemistry letters (01.02.2017)
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Journal Article
Acrylonitrile Cross-Metathesis: Coaxing Olefin Metathesis Reactivity from a Reluctant Substrate
Crowe, William E, Goldberg, Daniel R
Published in Journal of the American Chemical Society (01.05.1995)
Published in Journal of the American Chemical Society (01.05.1995)
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Journal Article
Tryptophan hydroxylase 1 Inhibition Impacts Pulmonary Vascular Remodeling in Two Rat Models of Pulmonary Hypertension
Aiello, Robert J, Bourassa, Patricia-Ann, Zhang, Qing, Dubins, Jeffrey, Goldberg, Daniel R, De Lombaert, Stéphane, Humbert, Marc, Guignabert, Christophe, Cavasin, Maria A, McKinsey, Timothy A, Paralkar, Vishwas
Published in The Journal of pharmacology and experimental therapeutics (01.02.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2017)
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Journal Article
Discovery of spirocyclic proline tryptophan hydroxylase-1 inhibitors
Goldberg, Daniel R., De Lombaert, Stéphane, Aiello, Robert, Bourassa, Patricia, Barucci, Nicole, Zhang, Qing, Paralkar, Vishwas, Valentine, James, Zavadoski, William
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
Published in Bioorganic & medicinal chemistry letters (15.02.2016)
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Journal Article
Discovery of acyl guanidine tryptophan hydroxylase-1 inhibitors
Goldberg, Daniel R., De Lombaert, Stéphane, Aiello, Robert, Bourassa, Patricia, Barucci, Nicole, Zhang, Qing, Paralkar, Vishwas, Stein, Adam J., Valentine, Jim, Zavadoski, William
Published in Bioorganic & medicinal chemistry letters (15.06.2016)
Published in Bioorganic & medicinal chemistry letters (15.06.2016)
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Journal Article
Synthesis and SAR studies of indole-based MK2 inhibitors
Xiong, Zhaoming, Gao, Donghong Amy, Cogan, Derek A., Goldberg, Daniel R., Hao, Ming-Hong, Moss, Neil, Pack, Edward, Pargellis, Chris, Skow, Donna, Trieselmann, Thomas, Werneburg, Brian, White, Andre
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Journal Article
The discovery of carboline analogs as potent MAPKAP-K2 inhibitors
Wu, Jiang-Ping, Wang, Ji, Abeywardane, Asitha, Andersen, Denise, Emmanuel, Michel, Gautschi, Elda, Goldberg, Daniel R., Kashem, Mohammed A., Lukas, Susan, Mao, Wang, Martin, Leslie, Morwick, Tina, Moss, Neil, Pargellis, Christopher, Patel, Usha R., Patnaude, Lori, Peet, Gregory W., Skow, Donna, Snow, Roger J., Ward, Yancey, Werneburg, Brian, White, Andre
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
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Journal Article
Discovery and Optimization of p38 Inhibitors via Computer-Assisted Drug Design
Goldberg, Daniel R, Hao, Ming-Hong, Qian, Kevin C, Swinamer, Alan D, Gao, Donghong A, Xiong, Zhaoming, Sarko, Chris, Berry, Angela, Lord, John, Magolda, Ronald L, Fadra, Tazmeen, Kroe, Rachel R, Kukulka, Alison, Madwed, Jeffrey B, Martin, Leslie, Pargellis, Christopher, Skow, Donna, Song, Jinhua J, Tan, Zhulin, Torcellini, Carol A, Zimmitti, Clare S, Yee, Nathan K, Moss, Neil
Published in Journal of medicinal chemistry (23.08.2007)
Published in Journal of medicinal chemistry (23.08.2007)
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Journal Article
Discovery and characterization of the N-phenyl- N′-naphthylurea class of p38 kinase inhibitors
Cirillo, Pier F., Hickey, Eugene R., Moss, Neil, Breitfelder, Steffen, Betageri, Raj, Fadra, Tazmeen, Gaenzler, Faith, Gilmore, Thomas, Goldberg, Daniel R., Kamhi, Victor, Kirrane, Thomas, Kroe, Rachel R., Madwed, Jeffrey, Moriak, Monica, Netherton, Matthew, Pargellis, Christopher A., Patel, Usha R., Qian, Kevin C., Sharma, Rajiv, Sun, Sanxing, Swinamer, Alan, Torcellini, Carol, Takahashi, Hidenori, Tsang, Michele, Xiong, Zhaoming
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
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Journal Article
Second-Generation Lymphocyte Function-Associated Antigen-1 Inhibitors: 1H-Imidazo[1,2-α]imidazol-2-one Derivatives
Wu, Jiang-Ping, Emeigh, Jonathan, Gao, Donghong A, Goldberg, Daniel R, Kuzmich, Daniel, Miao, Clara, Potocki, Ian, Qian, Kevin C, Sorcek, Ronald J, Jeanfavre, Deborah D, Kishimoto, Kei, Mainolfi, Elizabeth A, Nabozny, Gerald, Peng, Charline, Reilly, Patricia, Rothlein, Robert, Sellati, Rosemarie H, Woska, Joseph R, Chen, Shirlynn, Gunn, Jocelyn A, O'Brien, Drane, Norris, Stephen H, Kelly, Terence A
Published in Journal of medicinal chemistry (21.10.2004)
Published in Journal of medicinal chemistry (21.10.2004)
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Journal Article
Optimization of 2-Phenylaminoimidazo[4,5-h]isoquinolin-9-ones: Orally Active Inhibitors of lck Kinase
Goldberg, Daniel R, Butz, Tanja, Cardozo, Mario G, Eckner, Robert J, Hammach, Abdelhakim, Huang, Jessica, Jakes, Scott, Kapadia, Suresh, Kashem, Mohammed, Lukas, Susan, Morwick, Tina M, Panzenbeck, Maret, Patel, Usha, Pav, Susan, Peet, Gregory W, Peterson, Jeffrey D, Prokopowicz, Anthony S, Snow, Roger J, Sellati, Rosemarie, Takahashi, Hidenori, Tan, Jonathan, Tschantz, Matt A, Wang, Xiao-Jun, Wang, Yong, Wolak, John, Xiong, Pla, Moss, Neil
Published in Journal of medicinal chemistry (10.04.2003)
Published in Journal of medicinal chemistry (10.04.2003)
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Journal Article
Discovery and SAR of novel [1,6]Naphthyridines as potent inhibitors of spleen tyrosine kinase (SYK)
Cywin, Charles L, Zhao, Bao-Ping, McNeil, Daniel W, Hrapchak, Matt, Prokopowicz, Anthony S, Goldberg, Daniel R, Morwick, Tina M, Gao, Amy, Jakes, Scott, Kashem, Mohammed, Magolda, Ronald L, Soll, Richard M, Player, Mark R, Bobko, Mark A, Rinker, James, DesJarlais, Renee L, Winters, Michael P
Published in Bioorganic & medicinal chemistry letters (17.04.2003)
Published in Bioorganic & medicinal chemistry letters (17.04.2003)
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Journal Article
SPIROCYCLIC COMPOUNDS AS TRYPTOPHAN HYDROXYLASE INHIBITORS
SJOGREN ERIC BRIAN, SCRIBNER ANDREW, GOLDBERG DANIEL R, BRAMELD KENNETH, DE LOMBAERT STEPHANE
Year of Publication 17.05.2016
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Year of Publication 17.05.2016
Patent
Preparation of allylsilanes via cross-metathesis
Crowe, William E., Goldberg, Daniel R., Zhang, Zhijia J.
Published in Tetrahedron letters (25.03.1996)
Published in Tetrahedron letters (25.03.1996)
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Journal Article