Toxicity and Efficacy of a Novel GADD34-expressing Oncolytic HSV-1 for the Treatment of Experimental Glioblastoma
Nakashima, Hiroshi, Nguyen, Tran, Kasai, Kazue, Passaro, Carmela, Ito, Hirotaka, Goins, William F, Shaikh, Imran, Erdelyi, Ronald, Nishihara, Reiko, Nakano, Ichiro, Reardon, David A, Anderson, Ana C, Kuchroo, Vijay, Chiocca, E Antonio
Published in Clinical cancer research (01.06.2018)
Published in Clinical cancer research (01.06.2018)
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Herpes simplex viral-vector design for efficient transduction of nonneuronal cells without cytotoxicity
Miyagawa, Yoshitaka, Marino, Pietro, Verlengia, Gianluca, Uchida, Hiroaki, Goins, William F., Yokota, Shinichiro, Geller, David A., Yoshida, Osamu, Mester, Joseph, Cohen, Justus B., Glorioso, Joseph C.
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (31.03.2015)
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Use of miRNA Response Sequences to Block Off-target Replication and Increase the Safety of an Unattenuated, Glioblastoma-targeted Oncolytic HSV
Mazzacurati, Lucia, Marzulli, Marco, Reinhart, Bonnie, Miyagawa, Yoshitaka, Uchida, Hiroaki, Goins, William F, Li, Aofei, Kaur, Balveen, Caligiuri, Michael, Cripe, Timothy, Chiocca, Nino, Amankulor, Nduka, Cohen, Justus B, Glorioso, Joseph C, Grandi, Paola
Published in Molecular therapy (01.01.2015)
Published in Molecular therapy (01.01.2015)
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Gene therapy for the treatment of chronic peripheral nervous system pain
Goins, William F, Cohen, Justus B, Glorioso, Joseph C
Published in Neurobiology of disease (01.11.2012)
Published in Neurobiology of disease (01.11.2012)
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Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma
Nakashima, Hiroshi, Kaufmann, Johanna K, Wang, Pin-Yi, Nguyen, Tran, Speranza, Maria-Carmela, Kasai, Kazue, Okemoto, Kazuo, Otsuki, Akihiro, Nakano, Ichiro, Fernandez, Soledad, Goins, William F, Grandi, Paola, Glorioso, Joseph C, Lawler, Sean, Cripe, Timothy P, Chiocca, E Antonio
Published in The Journal of clinical investigation (01.11.2015)
Published in The Journal of clinical investigation (01.11.2015)
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Varicella-zoster virus early infection but not complete replication is required for the induction of chronic hypersensitivity in rat models of postherpetic neuralgia
Warner, Benjamin E, Yee, Michael B, Zhang, Mingdi, Hornung, Rebecca S, Kaufer, Benedikt B, Visalli, Robert J, Kramer, Phillip R, Goins, William F, Kinchington, Paul R
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Published in PLoS pathogens (01.07.2021)
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Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells
Hall, Bonnie L, Leronni, Daniela, Miyagawa, Yoshitaka, Goins, William F, Glorioso, Joseph C, Cohen, Justus B
Published in International journal of molecular sciences (21.11.2020)
Published in International journal of molecular sciences (21.11.2020)
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Effective Treatment of an Orthotopic Xenograft Model of Human Glioblastoma Using an EGFR-retargeted Oncolytic Herpes Simplex Virus
Uchida, Hiroaki, Marzulli, Marco, Nakano, Kenji, Goins, William F, Chan, Janet, Hong, Chang-Sook, Mazzacurati, Lucia, Yoo, Ji Young, Haseley, Amy, Nakashima, Hiroshi, Baek, Hyunjung, Kwon, Heechung, Kumagai, Izumi, Kuroki, Masahide, Kaur, Balveen, Chiocca, E Antonio, Grandi, Paola, Cohen, Justus B, Glorioso, Joseph C
Published in Molecular therapy (01.03.2013)
Published in Molecular therapy (01.03.2013)
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Disease-modifying rdHSV-CA8 non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels
Zhuang, Gerald Z, Goins, William F, Kandel, Munal B, Marzulli, Marco, Zhang, Mingdi, Glorioso, Joseph C, Kang, Yuan, Levitt, Alexandra E, Sarantopoulos, Konstantinos D, Levitt, Roy C
Published in Frontiers in molecular neuroscience (17.07.2024)
Published in Frontiers in molecular neuroscience (17.07.2024)
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Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy
Jenner, Adrianne L., Smalley, Munisha, Goldman, David, Goins, William F., Cobbs, Charles S., Puchalski, Ralph B., Chiocca, E. Antonio, Lawler, Sean, Macklin, Paul, Goldman, Aaron, Craig, Morgan
Published in iScience (17.06.2022)
Published in iScience (17.06.2022)
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rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels
Kandel, Munal B, Zhuang, Gerald Z, Goins, William F, Marzulli, Marco, Zhang, Mingdi, Glorioso, Joseph C, Kang, Yuan, Levitt, Alexandra E, Kwok, Wai-Meng, Levitt, Roy C, Sarantopoulos, Konstantinos D
Published in Frontiers in molecular neuroscience (09.05.2024)
Published in Frontiers in molecular neuroscience (09.05.2024)
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Novel mutations in UL24 and gH rescue efficient infection of an HSV vector retargeted to TrkA
Marzulli, Marco, Hall, Bonnie L., Zhang, Mingdi, Goins, William F., Cohen, Justus B., Glorioso, Joseph C.
Published in Molecular therapy. Methods & clinical development (14.09.2023)
Published in Molecular therapy. Methods & clinical development (14.09.2023)
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GBM-Targeted oHSV Armed with Matrix Metalloproteinase 9 Enhances Anti-tumor Activity and Animal Survival
Sette, Paola, Amankulor, Nduka, Li, Aofei, Marzulli, Marco, Leronni, Daniela, Zhang, Mingdi, Goins, William F., Kaur, Balveen, Bolyard, Chelsea, Cripe, Timothy P., Yu, Jianhua, Chiocca, E. Antonio, Glorioso, Joseph C., Grandi, Paola
Published in Molecular therapy. Oncolytics (20.12.2019)
Published in Molecular therapy. Oncolytics (20.12.2019)
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A Double Mutation in Glycoprotein gB Compensates for Ineffective gD-Dependent Initiation of Herpes Simplex Virus Type 1 Infection
UCHIDA, Hiroaki, CHAN, Janet, GOINS, William F, GRANDI, Paola, KUMAGAI, Izumi, COHEN, Justus B, GLORIOSO, Joseph C
Published in Journal of Virology (01.12.2010)
Published in Journal of Virology (01.12.2010)
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Myelolytic Treatments Enhance Oncolytic Herpes Virotherapy in Models of Ewing Sarcoma by Modulating the Immune Microenvironment
Denton, Nicholas L., Chen, Chun-Yu, Hutzen, Brian, Currier, Mark A., Scott, Thomas, Nartker, Brooke, Leddon, Jennifer L., Wang, Pin-Yi, Srinivas, Rachelle, Cassady, Kevin A., Goins, William F., Cripe, Timothy P.
Published in Molecular therapy. Oncolytics (21.12.2018)
Published in Molecular therapy. Oncolytics (21.12.2018)
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Treatment of glioblastoma with current oHSV variants reveals differences in efficacy and immune cell recruitment
Jackson, Joseph W., Hall, Bonnie L., Marzulli, Marco, Shah, Vrusha K., Bailey, Lisa, Chiocca, E. Antonio, Goins, William F., Kohanbash, Gary, Cohen, Justus B., Glorioso, Joseph C.
Published in Molecular therapy. Oncolytics (24.09.2021)
Published in Molecular therapy. Oncolytics (24.09.2021)
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Protocol Optimization for the Production of the Non-Cytotoxic JΔNI5 HSV Vector Deficient in Expression of Immediately Early Genes
Kuroda, Seiji, Miyagawa, Yoshitaka, Sato, Yuriko, Yamamoto, Motoko, Adachi, Kumi, Kinoh, Hiromi, Goins, William F., Cohen, Justus B., Glorioso, Joseph C., Taniai, Nobuhiko, Yoshida, Hiroshi, Okada, Takashi
Published in Molecular therapy. Methods & clinical development (12.06.2020)
Published in Molecular therapy. Methods & clinical development (12.06.2020)
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Equine Herpesvirus 1 Enters Cells by Two Different Pathways, and Infection Requires the Activation of the Cellular Kinase ROCK1
FRAMPTON, Arthur R, STOLZ, Donna B, UCHIDA, Hiroaki, GOINS, William F, COHEN, Justus B, GLORIOSO, Joseph C
Published in Journal of Virology (01.10.2007)
Published in Journal of Virology (01.10.2007)
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Interferon-stimulated Gene 15 (ISG15) and ISG15-linked Proteins Can Associate with Members of the Selective Autophagic Process, Histone Deacetylase 6 (HDAC6) and SQSTM1/p62
Nakashima, Hiroshi, Nguyen, Tran, Goins, William F., Chiocca, Ennio Antonio
Published in The Journal of biological chemistry (16.01.2015)
Published in The Journal of biological chemistry (16.01.2015)
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Suppression of detrusor-sphincter dyssynergia by herpes simplex virus vector mediated gene delivery of glutamic acid decarboxylase in spinal cord injured rats
Miyazato, Minoru, Sugaya, Kimio, Saito, Seiichi, Chancellor, Michael B, Goins, William F, Goss, James R, de Groat, William C, Glorioso, Joseph C, Yoshimura, Naoki
Published in The Journal of urology (01.09.2010)
Published in The Journal of urology (01.09.2010)
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