Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2
Wang, Jia, Cheng, Peng, Pavlyukov, Marat S, Yu, Hai, Zhang, Zhuo, Kim, Sung-Hak, Minata, Mutsuko, Mohyeldin, Ahmed, Xie, Wanfu, Chen, Dongquan, Goidts, Violaine, Frett, Brendan, Hu, Wenhao, Li, Hongyu, Shin, Yong Jae, Lee, Yeri, Nam, Do-Hyun, Kornblum, Harley I, Wang, Maode, Nakano, Ichiro
Published in The Journal of clinical investigation (01.08.2017)
Published in The Journal of clinical investigation (01.08.2017)
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Journal Article
Rapid-CNS2: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study
Patel, Areeba, Dogan, Helin, Payne, Alexander, Krause, Elena, Sievers, Philipp, Schoebe, Natalie, Schrimpf, Daniel, Blume, Christina, Stichel, Damian, Holmes, Nadine, Euskirchen, Philipp, Hench, Jürgen, Frank, Stephan, Rosenstiel-Goidts, Violaine, Ratliff, Miriam, Etminan, Nima, Unterberg, Andreas, Dieterich, Christoph, Herold-Mende, Christel, Pfister, Stefan M., Wick, Wolfgang, Loose, Matthew, von Deimling, Andreas, Sill, Martin, Jones, David T. W., Schlesner, Matthias, Sahm, Felix
Published in Acta neuropathologica (01.05.2022)
Published in Acta neuropathologica (01.05.2022)
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Differentiation therapy exerts antitumor effects on stem-like glioma cells
Campos, Benito, Wan, Feng, Farhadi, Mohammad, Ernst, Aurélie, Zeppernick, Felix, Tagscherer, Katrin E, Ahmadi, Rezvan, Lohr, Jennifer, Dictus, Christine, Gdynia, Georg, Combs, Stephanie E, Goidts, Violaine, Helmke, Burkhard M, Eckstein, Volker, Roth, Wilfried, Beckhove, Philipp, Lichter, Peter, Unterberg, Andreas, Radlwimmer, Bernhard, Herold-Mende, Christel
Published in Clinical cancer research (15.05.2010)
Published in Clinical cancer research (15.05.2010)
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Journal Article
Targeting atypical protein kinase C iota reduces viability in glioblastoma stem‐like cells via a notch signaling mechanism
Phillips, Emma, Lang, Verena, Bohlen, Jonathan, Bethke, Frederic, Puccio, Laura, Tichy, Diana, Herold‐Mende, Christel, Hielscher, Thomas, Lichter, Peter, Goidts, Violaine
Published in International journal of cancer (15.10.2016)
Published in International journal of cancer (15.10.2016)
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Journal Article
LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem-Like Cells
Nakata, Susumu, Campos, Benito, Bageritz, Josephine, Lorenzo Bermejo, Justo, Becker, Natalia, Engel, Felix, Acker, Till, Momma, Stefan, Herold-Mende, Christel, Lichter, Peter, Radlwimmer, Bernhard, Goidts, Violaine
Published in Brain pathology (Zurich, Switzerland) (01.01.2013)
Published in Brain pathology (Zurich, Switzerland) (01.01.2013)
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Journal Article
A Dereplication and Bioguided Discovery Approach to Reveal New Compounds from a Marine-Derived Fungus Stilbella fimetaria
Kildgaard, Sara, Subko, Karolina, Phillips, Emma, Goidts, Violaine, de la Cruz, Mercedes, Díaz, Caridad, Gotfredsen, Charlotte H, Andersen, Birgitte, Frisvad, Jens C, Nielsen, Kristian F, Larsen, Thomas O
Published in Marine drugs (13.08.2017)
Published in Marine drugs (13.08.2017)
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Journal Article
The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis
Augustin, Iris, Goidts, Violaine, Bongers, Angelika, Kerr, Grainne, Vollert, Gordon, Radlwimmer, Bernhard, Hartmann, Christian, Herold‐Mende, Christel, Reifenberger, Guido, von Deimling, Andreas, Boutros, Michael
Published in EMBO molecular medicine (01.01.2012)
Published in EMBO molecular medicine (01.01.2012)
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Journal Article
PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma
Phillips, Emma, Balss, Jörg, Bethke, Frederic, Pusch, Stefan, Christen, Stefan, Hielscher, Thomas, Schnölzer, Martina, Fletcher, Michael N. C., Habel, Antje, Tessmer, Claudia, Brenner, Lisa-Marie, Göttmann, Mona, Capper, David, Herold-Mende, Christel, von Deimling, Andreas, Fendt, Sarah-Maria, Goidts, Violaine
Published in Oncogenesis (New York, NY) (17.09.2022)
Published in Oncogenesis (New York, NY) (17.09.2022)
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Journal Article
PERK-mediated expression of peptidylglycine α-amidating monooxygenase supports angiogenesis in glioblastoma
Soni, Himanshu, Bode, Julia, Nguyen, Chi D L, Puccio, Laura, Neßling, Michelle, Piro, Rosario M, Bub, Jonas, Phillips, Emma, Ahrends, Robert, Eipper, Betty A, Tews, Björn, Goidts, Violaine
Published in Oncogenesis (New York, NY) (13.02.2020)
Published in Oncogenesis (New York, NY) (13.02.2020)
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Journal Article
Complex patterns of copy number variation at sites of segmental duplications : an important category of structural variation in the human genome
GOIDTS, Violaine, COOPER, David N, ARMENGOL, Lluis, SCHEMPP, Werner, CONROY, Jeffrey, ESTIVILL, Xavier, NOWAK, Norma, HAMEISTER, Horst, KEHRER-SAWATZKI, Hildegard
Published in Human genetics (01.09.2006)
Published in Human genetics (01.09.2006)
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Journal Article
Proteomic, Metabolomic, and Fatty Acid Profiling of Small Extracellular Vesicles from Glioblastoma Stem-Like Cells and Their Role in Tumor Heterogeneity
Lokumcu, Tolga, Iskar, Murat, Schneider, Martin, Helm, Dominic, Klinke, Glynis, Schlicker, Lisa, Bethke, Frederic, Müller, Gabriele, Richter, Karsten, Poschet, Gernot, Phillips, Emma, Goidts, Violaine
Published in ACS nano (23.01.2024)
Published in ACS nano (23.01.2024)
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Journal Article
Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-κB-dependent Manner
Kim, Sung-Hak, Ezhilarasan, Ravesanker, Phillips, Emma, Gallego-Perez, Daniel, Sparks, Amanda, Taylor, David, Ladner, Katherine, Furuta, Takuya, Sabit, Hemragul, Chhipa, Rishi, Cho, Ju Hwan, Mohyeldin, Ahmed, Beck, Samuel, Kurozumi, Kazuhiko, Kuroiwa, Toshihiko, Iwata, Ryoichi, Asai, Akio, Kim, Jonghwan, Sulman, Erik P., Cheng, Shi-Yuan, Lee, L. James, Nakada, Mitsutoshi, Guttridge, Denis, DasGupta, Biplab, Goidts, Violaine, Bhat, Krishna P., Nakano, Ichiro
Published in Cancer cell (08.02.2016)
Published in Cancer cell (08.02.2016)
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Journal Article
Integration of transcriptomics, proteomics and loss-of-function screening reveals WEE1 as a target for combination with dasatinib against proneural glioblastoma
Alhalabi, Obada T., Göttmann, Mona, Gold, Maxwell P., Schlue, Silja, Hielscher, Thomas, Iskar, Murat, Kessler, Tobias, Hai, Ling, Lokumcu, Tolga, Cousins, Clara C., Herold-Mende, Christel, Heßling, Bernd, Horschitz, Sandra, Jabali, Ammar, Koch, Philipp, Baumgartner, Ulrich, Day, Bryan W., Wick, Wolfgang, Sahm, Felix, Krieg, Sandro M., Fraenkel, Ernest, Phillips, Emma, Goidts, Violaine
Published in Cancer letters (25.09.2024)
Published in Cancer letters (25.09.2024)
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Journal Article
Intratumoral spatial heterogeneity of BTK kinomic activity dictates distinct therapeutic response within a single glioblastoma tumor
Ibrahim, Ahmed N, Yamashita, Daisuke, Anderson, Joshua C, Abdelrashid, Moaaz, Alwakeal, Amr, Estevez-Ordonez, Dagoberto, Komarova, Svetlana, Markert, James M, Goidts, Violaine, Willey, Christopher D, Nakano, Ichiro
Published in Journal of neurosurgery (01.12.2020)
Published in Journal of neurosurgery (01.12.2020)
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Journal Article
A novel patient stratification strategy to enhance the therapeutic efficacy of dasatinib in glioblastoma
Alhalabi, Obada T, Fletcher, Michael N C, Hielscher, Thomas, Kessler, Tobias, Lokumcu, Tolga, Baumgartner, Ulrich, Wittmann, Elena, Schlue, Silja, Göttmann, Mona, Rahman, Shaman, Hai, Ling, Hansen-Palmus, Lea, Puccio, Laura, Nakano, Ichiro, Herold-Mende, Christel, Day, Bryan W, Wick, Wolfgang, Sahm, Felix, Phillips, Emma, Goidts, Violaine
Published in Neuro-oncology (Charlottesville, Va.) (05.01.2022)
Published in Neuro-oncology (Charlottesville, Va.) (05.01.2022)
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Journal Article
PATH-64. COMPREHENSIVE CNS TUMOUR MOLECULAR DIAGNOSTICS USING THIRD GENERATION SEQUENCING
Patel, Areeba, Hinz, Felix, Dogan, Helin, Goebel, Kirsten, Schrimpf, Daniel, Goeller, Pauline, Ritter, Michael, Pfeifer, Lisa, Blume, Christina, Berghaus, Natalie, Payne, Alexander, Goidts, Violaine, Loose, Matthew, Unterberg, Andreas, Wick, Wolfgang, Pfister, Stefan, Sill, Martin, von Deimling, Andreas, Jones, David, Schlesner, Matthias, Sahm, Felix
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
Published in Neuro-oncology (Charlottesville, Va.) (10.11.2023)
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Journal Article
Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2
Wang, Jia, Cheng, Peng, Pavlyukov, Marat S, Yu, Hai, Zhang, Zhuo, Kim, Sung-Hak, Minata, Mutsuko, Mohyeldin, Ahmed, Xie, Wanfu, Chen, Dongquan, Goidts, Violaine, Frett, Brendan, Hu, Wenhao, Li, Hongyu, Shin, Yong Jae, Lee, Yeri, Nam, Do-Hyun, Kornblum, Harley I, Wang, Maode, Nakano, Ichiro
Published in The Journal of clinical investigation (01.11.2020)
Published in The Journal of clinical investigation (01.11.2020)
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Journal Article
Aberrant self-renewal and quiescence contribute to the aggressiveness of glioblastoma
Campos, Benito, Gal, Zoltan, Baader, Aline, Schneider, Tilman, Sliwinski, Christopher, Gassel, Kristina, Bageritz, Josephine, Grabe, Niels, von Deimling, Andreas, Beckhove, Philipp, Mogler, Carolin, Goidts, Violaine, Unterberg, Andreas, Eckstein, Volker, Herold-Mende, Christel
Published in The Journal of pathology (01.09.2014)
Published in The Journal of pathology (01.09.2014)
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Journal Article
PATH-46. COMPUTATIONAL HISTOPATHOLOGY INFORMED RAPID TARGETED NANOPORE SEQUENCING ENABLES AFFORDABLE NEXT DAY REPORTING OF COMPREHENSIVE MOLECULAR MARKERS FOR CNS TUMOUR DIAGNOSTICS
Patel, Areeba, Dogan, Helin, Jung, Alexander, Seferbekova, Zaira, Payne, Alexander, Ritter, Michael, Schrimpf, Daniel, Stichel, Damian, Hamelmann, Stefan, Blume, Christina, Euskirchen, Philipp, Goidts, Violaine, Sill, Martin, Pfister, Stefan, Loose, Matthew, Wick, Wolfgang, von Deimling, Andreas, Jones, David T, Schlesner, Matthias, Gerstung, Moritz, Sahm, Felix
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
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