A mouse knockout library for secreted and transmembrane proteins
de Sauvage, Frederic J, Tang, Tracy, Li, Li, Tang, Jerry, Li, Yun, Lin, Wei Yu, Martin, Flavius, Grant, Deanna, Solloway, Mark, Parker, Leon, Ye, Weilan, Forrest, William, Ghilardi, Nico, Oravecz, Tamas, Platt, Kenneth A, Rice, Dennis S, Hansen, Gwenn M, Abuin, Alejandro, Eberhart, Derek E, Godowski, Paul, Holt, Kathleen H, Peterson, Andrew, Zambrowicz, Brian P
Published in Nature biotechnology (01.07.2010)
Published in Nature biotechnology (01.07.2010)
Get full text
Journal Article
Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848
Levy, Ofer, Zarember, Kol A, Roy, Rene M, Cywes, Colette, Godowski, Paul J, Wessels, Michael R
Published in The Journal of immunology (1950) (01.10.2004)
Published in The Journal of immunology (1950) (01.10.2004)
Get full text
Journal Article
Activation of Toll-Like Receptor 2 in Acne Triggers Inflammatory Cytokine Responses
Kim, Jenny, Ochoa, Maria-Teresa, Krutzik, Stephan R, Takeuchi, Osamu, Uematsu, Satoshi, Legaspi, Annaliza J, Brightbill, Hans D, Holland, Diana, Cunliffe, William J, Akira, Shizuo, Sieling, Peter A, Godowski, Paul J, Modlin, Robert L
Published in The Journal of immunology (1950) (01.08.2002)
Published in The Journal of immunology (1950) (01.08.2002)
Get full text
Journal Article
APC-Independent Activation of NK Cells by the Toll-Like Receptor 3 Agonist Double-Stranded RNA
Schmidt, Kerstin N, Leung, Beatrice, Kwong, Mandy, Zarember, Kol A, Satyal, Sanjeev, Navas, Tony A, Wang, Fay, Godowski, Paul J
Published in The Journal of immunology (1950) (01.01.2004)
Published in The Journal of immunology (1950) (01.01.2004)
Get full text
Journal Article
Activation and regulation of Toll-like receptors 2 and 1 in human leprosy
Modlin, Robert L, Krutzik, Stephan R, Ochoa, Maria Teresa, Sieling, Peter A, Uematsu, Satoshi, Ng, Yolanda W, Legaspi, Annaliza, Liu, Philip T, Cole, Stewart T, Godowski, Paul J, Maeda, Yumi, Sarno, Euzenir N, Norgard, Michael V, Brennan, Patrick J, Akira, Shizuo, Rea, Thomas H
Published in Nature medicine (01.05.2003)
Published in Nature medicine (01.05.2003)
Get full text
Journal Article
Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2
Hertz, Cheryl J, Wu, Qi, Porter, Edith Martin, Zhang, Yan J, Weismüller, Karl-Heinz, Godowski, Paul J, Ganz, Tomas, Randell, Scott H, Modlin, Robert L
Published in The Journal of immunology (1950) (15.12.2003)
Published in The Journal of immunology (1950) (15.12.2003)
Get full text
Journal Article
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism
Tapping, Richard I, Mathison, John C, Kravchenko, Vladimir, Tobias, Peter S, Kirschning, Carsten J, Chuang, Tsung-Hsien, Godowski, Paul J, Werts, Catherine, Haake, David A, Hayashi, Fumitaka, Wagner, Hermann, Saint Girons, Isabelle, Aderem, Alan, Ozinsky, Adrian, Ulevitch, Richard J, Underhill, David M
Published in Nature immunology (01.04.2001)
Published in Nature immunology (01.04.2001)
Get full text
Journal Article
Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-Like Receptor-2
Aliprantis, Antonios O., Yang, Ruey-Bing, Mark, Melanie R., Suggett, Shelly, Devaux, Brigitte, Radolf, Justin D., Klimpel, Gary R., Godowski, Paul, Zychlinsky, Arturo
Published in Science (American Association for the Advancement of Science) (30.07.1999)
Published in Science (American Association for the Advancement of Science) (30.07.1999)
Get full text
Journal Article
Microbial Lipopeptides Stimulate Dendritic Cell Maturation Via Toll-Like Receptor 2
Hertz, Cheryl J, Kiertscher, Sylvia M, Godowski, Paul J, Bouis, Deborah A, Norgard, Michael V, Roth, Michael D, Modlin, Robert L
Published in The Journal of immunology (1950) (15.02.2001)
Published in The Journal of immunology (1950) (15.02.2001)
Get full text
Journal Article
Toll-Like Receptor 4, But Not Toll-Like Receptor 2, Is a Signaling Receptor for Escherichia and Salmonella Lipopolysaccharides
Tapping, Richard I, Akashi, Sachiko, Miyake, Kensuke, Godowski, Paul J, Tobias, Peter S
Published in The Journal of immunology (1950) (15.11.2000)
Published in The Journal of immunology (1950) (15.11.2000)
Get full text
Journal Article
An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases
Xie, Markus M, Dai, Bingbing, Hackney, Jason A, Sun, Tianhe, Zhang, Juan, Jackman, Janet K, Jeet, Surinder, Irizarry-Caro, Ricardo A, Fu, Yongyao, Liang, Yuxin, Bender, Hannah, Shamir, Eliah R, Keir, Mary E, Bevers, Jack, Nakamura, Gerald, Townsend, Michael J, Fox, David A, Scherl, Alexis, Lee, Wyne P, Martin, Flavius, Godowski, Paul J, Pappu, Rajita, Yi, Tangsheng
Published in Cell reports. Medicine (15.08.2023)
Published in Cell reports. Medicine (15.08.2023)
Get full text
Journal Article
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
Godowski, Paul J, Yang, Ruey-Bing, Mark, Melanie R, Gray, Alane, Huang, Arthur, Xie, Ming Hong, Zhang, Min, Goddard, Audrey, Wood, William I, Gurney, Austin L
Published in Nature (London) (17.09.1998)
Published in Nature (London) (17.09.1998)
Get full text
Journal Article
Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors
Sheridan, James P., Marsters, Scot A., Pitti, Robert M., Gurney, Austin, Skubatch, Maya, Baldwin, Daryl, Ramakrishnan, Lakshmi, Gray, Christa L., Baker, Kevin, Wood, William I., Goddard, Audrey D., Godowski, Paul, Ashkenazi, Avi
Published in Science (American Association for the Advancement of Science) (08.08.1997)
Published in Science (American Association for the Advancement of Science) (08.08.1997)
Get full text
Journal Article
Signaling Events Induced by Lipopolysaccharide-Activated Toll-Like Receptor 2
Yang, Ruey-Bing, Mark, Melanie R, Gurney, Austin L, Godowski, Paul J
Published in The Journal of immunology (1950) (15.07.1999)
Published in The Journal of immunology (1950) (15.07.1999)
Get full text
Journal Article
Toll-Like Receptor 2 Ligands as Adjuvants for Human Th1 Responses
Sieling, Peter A, Chung, Woosin, Duong, Baochau T, Godowski, Paul J, Modlin, Robert L
Published in The Journal of immunology (1950) (01.01.2003)
Published in The Journal of immunology (1950) (01.01.2003)
Get full text
Journal Article
Activation of Toll-Like Receptor 2 on Human Dendritic Cells Triggers Induction of IL-12, But Not IL-10
Thoma-Uszynski, Sybille, Kiertscher, Sylvia M, Ochoa, Maria Teresa, Bouis, Deborah A, Norgard, Michael V, Miyake, Kensuke, Godowski, Paul J, Roth, Michael D, Modlin, Robert L
Published in The Journal of immunology (1950) (01.10.2000)
Published in The Journal of immunology (1950) (01.10.2000)
Get full text
Journal Article