Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
Bonner, Caroline, Kerr-Conte, Julie, Gmyr, Valéry, Queniat, Gurvan, Moerman, Ericka, Thévenet, Julien, Beaucamps, Cédric, Delalleau, Nathalie, Popescu, Iuliana, Malaisse, Willy J, Sener, Abdullah, Deprez, Benoit, Abderrahmani, Amar, Staels, Bart, Pattou, François
Published in Nature medicine (01.05.2015)
Published in Nature medicine (01.05.2015)
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Journal Article
Ten-Year Outcome of Islet Alone or Islet After Kidney Transplantation in Type 1 Diabetes: A Prospective Parallel-Arm Cohort Study
Vantyghem, Marie-Christine, Chetboun, Mikael, Gmyr, Valéry, Jannin, Arnaud, Espiard, Stéphanie, Le Mapihan, Kristell, Raverdy, Violeta, Delalleau, Nathalie, Machuron, François, Hubert, Thomas, Frimat, Marie, Van Belle, Eric, Hazzan, Marc, Pigny, Pascal, Noel, Christian, Caiazzo, Robert, Kerr-Conte, Julie, Pattou, François
Published in Diabetes care (01.11.2019)
Published in Diabetes care (01.11.2019)
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Journal Article
Endoplasmic Reticulum Stress Links Oxidative Stress to Impaired Pancreatic Beta-Cell Function Caused by Human Oxidized LDL
Plaisance, Valérie, Brajkovic, Saška, Tenenbaum, Mathie, Favre, Dimitri, Ezanno, Hélène, Bonnefond, Amélie, Bonner, Caroline, Gmyr, Valéry, Kerr-Conte, Julie, Gauthier, Benoit R, Widmann, Christian, Waeber, Gérard, Pattou, François, Froguel, Philippe, Abderrahmani, Amar
Published in PloS one (16.09.2016)
Published in PloS one (16.09.2016)
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Journal Article
Continuous Glucose Monitoring after Islet Transplantation in Type 1 Diabetes: An Excellent Graft Function (β-Score Greater Than 7) Is Required to Abrogate Hyperglycemia, Whereas a Minimal Function Is Necessary to Suppress Severe Hypoglycemia (β-Score Greater Than 3)
Vantyghem, Marie-Christine, Raverdy, Violeta, Balavoine, Anne-Sophie, Defrance, Frédérique, Caiazzo, Robert, Arnalsteen, Laurent, Gmyr, Valéry, Hazzan, Marc, Noël, Christian, Kerr-Conte, Julie, Pattou, Francois
Published in The journal of clinical endocrinology and metabolism (01.11.2012)
Published in The journal of clinical endocrinology and metabolism (01.11.2012)
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Journal Article
The challenge of HLA donor specific antibodies in the management of pancreatic islet transplantation: an illustrative case-series
Maanaoui, Mehdi, Chetboun, Mikael, Top, Isabelle, Elsermans, Vincent, Kerr-Conte, Julie, Le Mapihan, Kristell, Defrance, Frederique, Gmyr, Valéry, Hubert, Thomas, Labalette, Myriam, Hazzan, Marc, Vantyghem, Marie-Christine, Pattou, François
Published in Scientific reports (21.07.2022)
Published in Scientific reports (21.07.2022)
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Journal Article
Interindividual Heterogeneity of SGLT2 Expression and Function in Human Pancreatic Islets
Saponaro, Chiara, Mühlemann, Markus, Acosta-Montalvo, Ana, Piron, Anthony, Gmyr, Valery, Delalleau, Nathalie, Moerman, Ericka, Thévenet, Julien, Pasquetti, Gianni, Coddeville, Anais, Cnop, Miriam, Kerr-Conte, Julie, Staels, Bart, Pattou, François, Bonner, Caroline
Published in Diabetes (New York, N.Y.) (01.05.2020)
Published in Diabetes (New York, N.Y.) (01.05.2020)
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Journal Article
The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development
Tenenbaum, Mathie, Plaisance, Valérie, Boutry, Raphael, Pawlowski, Valérie, Jacovetti, Cécile, Sanchez-Parra, Clara, Ezanno, Hélène, Bourry, Julien, Beeler, Nicole, Pasquetti, Gianni, Gmyr, Valery, Dalle, Stéphane, Kerr-Conte, Julie, Pattou, François, Hirai, Syu-ichi, Regazzi, Romano, Bonnefond, Amélie, Froguel, Philippe, Abderrahmani, Amar
Published in Cellular and molecular life sciences : CMLS (01.01.2021)
Published in Cellular and molecular life sciences : CMLS (01.01.2021)
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Journal Article
Coxsackievirus B4 can infect human pancreas ductal cells and persist in ductal-like cell cultures which results in inhibition of Pdx1 expression and disturbed formation of islet-like cell aggregates
Sane, Famara, Caloone, Delphine, Gmyr, Valéry, Engelmann, Ilka, Belaich, Sandrine, Kerr-Conte, Julie, Pattou, François, Desailloud, Rachel, Hober, Didier
Published in Cellular and molecular life sciences : CMLS (01.11.2013)
Published in Cellular and molecular life sciences : CMLS (01.11.2013)
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Journal Article
The NERP-4–SNAT2 axis regulates pancreatic β-cell maintenance and function
Zhang, Weidong, Miura, Ayako, Abu Saleh, Md Moin, Shimizu, Koichiro, Mita, Yuichiro, Tanida, Ryota, Hirako, Satoshi, Shioda, Seiji, Gmyr, Valery, Kerr-Conte, Julie, Pattou, Francois, Jin, Chunhuan, Kanai, Yoshikatsu, Sasaki, Kazuki, Minamino, Naoto, Sakoda, Hideyuki, Nakazato, Masamitsu
Published in Nature communications (09.12.2023)
Published in Nature communications (09.12.2023)
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Journal Article
The GLP1R Agonist Liraglutide Reduces Hyperglucagonemia Induced by the SGLT2 Inhibitor Dapagliflozin via Somatostatin Release
Saponaro, Chiara, Gmyr, Valéry, Thévenet, Julien, Moerman, Ericka, Delalleau, Nathalie, Pasquetti, Gianni, Coddeville, Anais, Quenon, Audrey, Daoudi, Mehdi, Hubert, Thomas, Vantyghem, Marie-Christine, Bousquet, Corinne, Martineau, Yvan, Kerr-Conte, Julie, Staels, Bart, Pattou, François, Bonner, Caroline
Published in Cell reports (Cambridge) (06.08.2019)
Published in Cell reports (Cambridge) (06.08.2019)
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Journal Article
PCSK9 is expressed in pancreatic δ-cells and does not alter insulin secretion
Langhi, Cédric, Le May, Cédric, Gmyr, Valéry, Vandewalle, Brigitte, Kerr-Conte, Julie, Krempf, Michel, Pattou, François, Costet, Philippe, Cariou, Bertrand
Published in Biochemical and biophysical research communications (25.12.2009)
Published in Biochemical and biophysical research communications (25.12.2009)
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Journal Article
Characterization of one anastomosis gastric bypass and impact of biliary and common limbs on bile acid and postprandial glucose metabolism in a minipig model
Marciniak, Camille, Chávez-Talavera, Oscar, Caiazzo, Robert, Hubert, Thomas, Zubiaga, Lorea, Baud, Gregory, Quenon, Audrey, Descat, Amandine, Vallez, Emmanuelle, Goossens, Jean François, Kouach, Mostafa, Vangelder, Vincent, Gobert, Mathilde, Daoudi, Mehdi, Derudas, Bruno, Pigny, Pascal, Klein, André, Gmyr, Valéry, Raverdy, Violeta, Lestavel, Sophie, Laferrère, Blandine, Staels, Bart, Tailleux, Anne, Pattou, François
Published in American journal of physiology: endocrinology and metabolism (01.04.2021)
Published in American journal of physiology: endocrinology and metabolism (01.04.2021)
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Journal Article
Effects of subtotal pancreatectomy and long‐term glucose and lipid overload on insulin secretion and glucose homeostasis in minipigs
Goutchtat, Rébecca, Quenon, Audrey, Clarisse, Manon, Delalleau, Nathalie, Coddeville, Anaïs, Gobert, Mathilde, Gmyr, Valéry, Kerr‐Conte, Julie, Pattou, François, Hubert, Thomas
Published in Endocrinology, diabetes & metabolism (01.07.2023)
Published in Endocrinology, diabetes & metabolism (01.07.2023)
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Journal Article
Primary Graft Function, Metabolic Control, and Graft Survival After Islet Transplantation
Vantyghem, Marie-Christine, Kerr-Conte, Julie, Arnalsteen, Laurent, Sergent, Geraldine, Defrance, Frederique, Gmyr, Valery, Declerck, Nicole, Raverdy, Violeta, Vandewalle, Brigitte, Pigny, Pascal, Noel, Christian, Pattou, Francois
Published in Diabetes care (01.08.2009)
Published in Diabetes care (01.08.2009)
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Journal Article
Erratum. Ten-Year Outcome of Islet Alone or Islet After Kidney Transplantation in Type 1 Diabetes: A Prospective Parallel-Arm Cohort Study. Diabetes Care 2019;42:2042-2049
Vantyghem, Marie-Christine, Chetboun, Mikael, Gmyr, Valéry, Jannin, Arnaud, Espiard, Stéphanie, Le Mapihan, Kristell, Raverdy, Violeta, Delalleau, Nathalie, Machuron, François, Hubert, Thomas, Frimat, Marie, Van Belle, Eric, Hazzan, Marc, Pigny, Pascal, Noel, Christian, Caiazzo, Robert, Kerr-Conte, Julie, Pattou, François
Published in Diabetes care (01.05.2020)
Published in Diabetes care (01.05.2020)
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Journal Article
Coxsackievirus-B4 Infection Can Induce the Expression of Human Endogenous Retrovirus W in Primary Cells
Dechaumes, Arthur, Bertin, Antoine, Sane, Famara, Levet, Sandrine, Varghese, Jennifer, Charvet, Benjamin, Gmyr, Valéry, Kerr-Conte, Julie, Pierquin, Justine, Arunkumar, Govindakarnavar, Pattou, François, Perron, Hervé, Hober, Didier
Published in Microorganisms (Basel) (01.09.2020)
Published in Microorganisms (Basel) (01.09.2020)
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Journal Article
Coxsackievirus-B4 Infection of Human Primary Pancreatic Ductal Cell Cultures Results in Impairment of Differentiation into Insulin-Producing Cells
Bertin, Antoine, Sane, Famara, Gmyr, Valery, Lobert, Delphine, Dechaumes, Arthur, Kerr-Conte, Julie, Pattou, François, Hober, Didier
Published in Viruses (02.07.2019)
Published in Viruses (02.07.2019)
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Journal Article
mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells
Le Bacquer, Olivier, Queniat, Gurvan, Gmyr, Valery, Kerr-Conte, Julie, Lefebvre, Bruno, Pattou, François
Published in Journal of endocrinology (01.01.2013)
Published in Journal of endocrinology (01.01.2013)
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Journal Article
Human Recombinant Antithrombin (ATryn®) Administration Improves Survival and Prevents Intravascular Coagulation after Intraportal Islet Transplantation in a Piglet Model
Gmyr, Valery, Bonner, Caroline, Moerman, Ericka, Tournoys, Antoine, Delalleau, Nathalie, Quenon, Audrey, Thevenet, Julien, Chetboun, Mikael, Kerr-Conte, Julie, Pattou, François, Hubert, Thomas, Jourdain, Merce
Published in Cell transplantation (01.02.2017)
Published in Cell transplantation (01.02.2017)
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Journal Article
Impact of Procedure-Related Complications on Long-term Islet Transplantation Outcome
Caiazzo, Robert, Vantyghem, Marie-Christine, Raverdi, Violeta, Bonner, Caroline, Gmyr, Valery, Defrance, Frederique, Leroy, Clara, Sergent, Geraldine, Hubert, Thomas, Ernst, Oliver, Noel, Christian, Kerr-Conte, Julie, Pattou, François
Published in Transplantation (01.05.2015)
Published in Transplantation (01.05.2015)
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