Phthalazinone-based lactams and cyclic ureas as ROCK2 selective inhibitors
Hu, Zilun, Sitkoff, Doree, Glunz, Peter W., Zou, Yan, Wang, Cailan, Muckelbauer, Jodi K., Adam, Leonard P., Wexler, Ruth R., Quan, Mimi L.
Published in Bioorganic & medicinal chemistry letters (15.05.2023)
Published in Bioorganic & medicinal chemistry letters (15.05.2023)
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P2Y6 receptor potentiates pro-inflammatory responses in macrophages and exhibits differential roles in atherosclerotic lesion development
Garcia, Ricardo A, Yan, Mujing, Search, Debra, Zhang, Rongan, Carson, Nancy L, Ryan, Carol S, Smith-Monroy, Constance, Zheng, Joanna, Chen, Jian, Kong, Yan, Tang, Huaping, Hellings, Samuel E, Wardwell-Swanson, Judith, Dinchuk, Joseph E, Psaltis, George C, Gordon, David A, Glunz, Peter W, Gargalovic, Peter S
Published in PloS one (31.10.2014)
Published in PloS one (31.10.2014)
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Journal Article
Atropisomer Control in Macrocyclic Factor VIIa Inhibitors
Glunz, Peter W, Mueller, Luciano, Cheney, Daniel L, Ladziata, Vladimir, Zou, Yan, Wurtz, Nicholas R, Wei, Anzhi, Wong, Pancras C, Wexler, Ruth R, Priestley, E. Scott
Published in Journal of medicinal chemistry (28.04.2016)
Published in Journal of medicinal chemistry (28.04.2016)
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Journal Article
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies
Hu, Zilun, Wang, Cailan, Glunz, Peter W., Li, Julia, Cheadle, Nathan L., Chen, Alice Y., Chen, Xue-Qing, Myers, Joseph E., Guarino, Victor R., Rose, Anne, Sack, John S., Sitkoff, Doree, Taylor, David S., Xu, Songmei, Yan, Chunhong, Zhang, Hongwei, Zhang, Lisa, Hennan, James, Adam, Leonard P., Wexler, Ruth R., Quan, Mimi L.
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
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Journal Article
Discovery of a Highly Potent, Selective, and Orally Bioavailable Macrocyclic Inhibitor of Blood Coagulation Factor VIIa–Tissue Factor Complex
Zhang, Xiaojun, Glunz, Peter W, Johnson, James A, Jiang, Wen, Jacutin-Porte, Swanee, Ladziata, Vladimir, Zou, Yan, Phillips, Monique S, Wurtz, Nicholas R, Parkhurst, Brandon, Rendina, Alan R, Harper, Timothy M, Cheney, Daniel L, Luettgen, Joseph M, Wong, Pancras C, Seiffert, Dietmar, Wexler, Ruth R, Priestley, E. Scott
Published in Journal of medicinal chemistry (11.08.2016)
Published in Journal of medicinal chemistry (11.08.2016)
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Journal Article
Correction to “Atropisomer Control in Macrocyclic Factor VIIa Inhibitors”
Glunz, Peter W, Mueller, Luciano, Cheney, Daniel L, Ladziata, Vladimir, Zou, Yan, Wurtz, Nicholas R, Wei, Anzhi, Wong, Pancras C, Wexler, Ruth R, Priestley, E. Scott
Published in Journal of medicinal chemistry (26.04.2018)
Published in Journal of medicinal chemistry (26.04.2018)
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Journal Article
Neutral macrocyclic factor VIIa inhibitors
Wurtz, Nicholas R., Parkhurst, Brandon L., DeLucca, Indawati, Glunz, Peter W., Jiang, Wen, Zhang, Xiaojun, Cheney, Daniel L., Bozarth, Jeffrey M., Rendina, Alan R., Wei, Anzhi, Harper, Tim, Luettgen, Joseph M., Wu, Yiming, Wong, Pancras C., Seiffert, Dietmar A., Wexler, Ruth R., Priestley, E. Scott
Published in Bioorganic & medicinal chemistry letters (15.06.2017)
Published in Bioorganic & medicinal chemistry letters (15.06.2017)
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Journal Article
Synthesis and P1′ SAR exploration of potent macrocyclic tissue factor-factor VIIa inhibitors
Ladziata, Vladimir (Uladzimir), Glunz, Peter W., Zou, Yan, Zhang, Xiaojun, Jiang, Wen, Jacutin-Porte, Swanee, Cheney, Daniel L., Wei, Anzhi, Luettgen, Joseph M., Harper, Timothy M., Wong, Pancras C., Seiffert, Dietmar, Wexler, Ruth R., Priestley, E. Scott
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
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Journal Article
Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors
Glunz, Peter W., Cheng, Xuhong, Cheney, Daniel L., Weigelt, Carolyn A., Wei, Anzhi, Luettgen, Joseph M., Wong, Pancras C., Wexler, Ruth R., Priestley, E. Scott
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
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Journal Article
Nonbenzamidine acylsulfonamide tissue factor–factor VIIa inhibitors
Glunz, Peter W., Zhang, Xiaojun, Zou, Yan, Delucca, Indawati, Nirschl, Alexandra H., Cheng, Xuhong, Weigelt, Carolyn A., Cheney, Daniel L., Wei, Anzhi, Anumula, Rushith, Luettgen, Joseph M., Rendina, Alan R., Harpel, Mark, Luo, Gang, Knabb, Robert, Wong, Pancras C., Wexler, Ruth R., Priestley, E. Scott
Published in Bioorganic & medicinal chemistry letters (15.09.2013)
Published in Bioorganic & medicinal chemistry letters (15.09.2013)
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Journal Article
On the Power of Chemical Synthesis: Immunological Evaluation of Models for Multiantigenic Carbohydrate-Based Cancer Vaccines
Ragupathi, Govindaswami, Coltart, Don M., Williams, Lawrence J., Koide, Fusataka, Kagan, Ella, Allen, Jennifer, Harris, Christina, Glunz, Peter W., Livingston, Philip O., Danishefsky, Samuel J.
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (15.10.2002)
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Journal Article
Principles of Mucin Architecture: Structural Studies on Synthetic Glycopeptides Bearing Clustered Mono-, Di-, Tri-, and Hexasaccharide Glycodomains
Coltart, Don M, Royyuru, Ajay K, Williams, Lawrence J, Glunz, Peter W, Sames, Dalibor, Kuduk, Scott D, Schwarz, Jacob B, Chen, Xiao-Tao, Danishefsky, Samuel J, Live, David H
Published in Journal of the American Chemical Society (21.08.2002)
Published in Journal of the American Chemical Society (21.08.2002)
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Journal Article
Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF–FVIIa inhibitors
Zhang, Xiaojun, Glunz, Peter W., Jiang, Wen, Schmitt, Aaron, Newman, Makenzie, Barbera, Frank A., Bozarth, Jeffery M., Rendina, Alan R., Wei, Anzhi, Wen, Xiao, Rossi, Karen A., Luettgen, Joseph M., Wong, Pancras C., Knabb, Robert M., Wexler, Ruth R., Scott Priestley, E.
Published in Bioorganic & medicinal chemistry letters (15.03.2013)
Published in Bioorganic & medicinal chemistry letters (15.03.2013)
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Journal Article
Synthetic and Immunological Studies on Clustered Modes of Mucin-Related Tn and TF O-Linked Antigens: The Preparation of a Glycopeptide-Based Vaccine for Clinical Trials against Prostate Cancer
Kuduk, Scott D, Schwarz, Jacob B, Chen, Xiao-Tao, Glunz, Peter W, Sames, Dalibor, Ragupathi, Govindaswami, Livingston, Philip O, Danishefsky, Samuel J
Published in Journal of the American Chemical Society (09.12.1998)
Published in Journal of the American Chemical Society (09.12.1998)
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Journal Article
Design and Synthesis of Phenylpyrrolidine Phenylglycinamides As Highly Potent and Selective TF-FVIIa Inhibitors
Zhang, Xiaojun, Jiang, Wen, Jacutin-Porte, Swanee, Glunz, Peter W, Zou, Yan, Cheng, Xuhong, Nirschl, Alexandra H, Wurtz, Nicholas R, Luettgen, Joseph M, Rendina, Alan R, Luo, Gang, Harper, Timothy M, Wei, Anzhi, Anumula, Rushith, Cheney, Daniel L, Knabb, Robert M, Wong, Pancras C, Wexler, Ruth R, Priestley, E. Scott
Published in ACS medicinal chemistry letters (13.02.2014)
Published in ACS medicinal chemistry letters (13.02.2014)
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Journal Article
A Broadly Applicable Method for the Efficient Synthesis of α-O-Linked Glycopeptides and Clustered Sialic Acid Residues
Schwarz, Jacob B, Kuduk, Scott D, Chen, Xiao-Tao, Sames, Dalibor, Glunz, Peter W, Danishefsky, Samuel J
Published in Journal of the American Chemical Society (31.03.1999)
Published in Journal of the American Chemical Society (31.03.1999)
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Journal Article
Design and synthesis of bicyclic pyrimidinone-based HCV NS3 protease inhibitors
Glunz, Peter W, Douty, Brent D, Decicco, Carl P
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
Published in Bioorganic & medicinal chemistry letters (10.03.2003)
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Journal Article
New Chemical Synthesis of the Promising Cancer Chemotherapeutic Agent 12,13-Desoxyepothilone B: Discovery of a Surprising Long-Range Effect on the Diastereoselectivity of an Aldol Condensation
Harris, Christina R, Kuduk, Scott D, Balog, Aaron, Savin, Ken, Glunz, Peter W, Danishefsky, Samuel J
Published in Journal of the American Chemical Society (04.08.1999)
Published in Journal of the American Chemical Society (04.08.1999)
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Journal Article
Probing Cell Surface “Glyco-Architecture” through Total Synthesis. Immunological Consequences of a Human Blood Group Determinant in a Clustered Mucin-like Context
Glunz, Peter W, Hintermann, Samuel, Schwarz, Jacob B, Kuduk, Scott D, Chen, Xiao-Tao, Williams, Lawrence J, Sames, Dalibor, Danishefsky, Samuel J, Kudryashov, Valery, Lloyd, Kenneth O
Published in Journal of the American Chemical Society (17.11.1999)
Published in Journal of the American Chemical Society (17.11.1999)
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