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Dual GIP and GLP-1 Receptor Agonist Tirzepatide Improves Beta-cell Function and Insulin Sensitivity in Type 2 Diabetes
Thomas, Melissa K, Nikooienejad, Amir, Bray, Ross, Cui, Xuewei, Wilson, Jonathan, Duffin, Kevin, Milicevic, Zvonko, Haupt, Axel, Robins, Deborah A
Published in The journal of clinical endocrinology and metabolism (01.02.2021)
Published in The journal of clinical endocrinology and metabolism (01.02.2021)
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Potential of Albiglutide, a Long-Acting GLP-1 Receptor Agonist, in Type 2 Diabetes: A randomized controlled trial exploring weekly, biweekly, and monthly dosing
Rosenstock, Julio, Reusch, Jane, Bush, Mark, Yang, Fred, Stewart, Murray
Published in Diabetes care (01.10.2009)
Published in Diabetes care (01.10.2009)
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LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept
Coskun, Tamer, Sloop, Kyle W., Loghin, Corina, Alsina-Fernandez, Jorge, Urva, Shweta, Bokvist, Krister B., Cui, Xuewei, Briere, Daniel A., Cabrera, Over, Roell, William C., Kuchibhotla, Uma, Moyers, Julie S., Benson, Charles T., Gimeno, Ruth E., D'Alessio, David A., Haupt, Axel
Published in Molecular metabolism (Germany) (01.12.2018)
Published in Molecular metabolism (Germany) (01.12.2018)
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Obese mice weight loss role on nonalcoholic fatty liver disease and endoplasmic reticulum stress treated by a GLP-1 receptor agonist
Pontes-da-Silva, Rayane Miranda, de Souza Marinho, Thatiany, de Macedo Cardoso, Luiz Eduardo, Mandarim-de-Lacerda, Carlos Alberto, Aguila, Marcia Barbosa
Published in International Journal of Obesity (01.01.2022)
Published in International Journal of Obesity (01.01.2022)
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Energy balance in hypothalamic obesity in response to treatment with a once-weekly GLP-1 receptor agonist
Shoemaker, Ashley H., Silver, Heidi J., Buchowski, Maciej, Slaughter, James C., Yanovski, Jack A., Elfers, Clinton, Roth, Christian L., Abuzzahab, M. Jennifer
Published in International Journal of Obesity (01.03.2022)
Published in International Journal of Obesity (01.03.2022)
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The GLP-1 receptor agonist liraglutide inhibits progression of vascular disease via effects on atherogenesis, plaque stability and endothelial function in an ApoE−/− mouse model
Gaspari, Tracey, Welungoda, Iresha, Widdop, Robert E, Simpson, Richard W, Dear, Anthony E
Published in Diabetes & vascular disease research (01.07.2013)
Published in Diabetes & vascular disease research (01.07.2013)
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95-LB: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Novel Oral Small Molecule GLP-1 Receptor Agonist (HRS-7535) in Healthy Subjects —A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single- and Multiple-Ascending Dose Study
WU, JINGYING, HU, WEI, DU, YIJUN, ZHANG, QIAN, ZHOU, RENPENG, ZHANG, QIN, QIN, HUILING, YE, ZI, XU, YIMEI, FENG, SHENG, SHU, CHANG, SHEN, YU, FAN, YANG
Published in Diabetes (New York, N.Y.) (20.06.2023)
Published in Diabetes (New York, N.Y.) (20.06.2023)
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Warfarin pharmacokinetics and pharmacodynamics are not affected by concomitant administration of the long-acting GLP-1 receptor agonist polyethylene glycol loxenatide
Zhou, Huili, Wu, Guolan, Lv, Duo, Lin, Meihua, Shentu, Jianzhong
Published in International journal of clinical pharmacology and therapeutics (01.02.2025)
Published in International journal of clinical pharmacology and therapeutics (01.02.2025)
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119-OR: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Novel Ultra-Long-Acting GLP-1 Receptor Agonist (ZT002) in Healthy Subjects
ZHANG, YUANYUAN, XU, XIUSEN, MCLENDON, KRISTI, WONG, ALEX H.L., ZHANG, YUYING, ZHANG, XUJIA
Published in Diabetes (New York, N.Y.) (14.06.2024)
Published in Diabetes (New York, N.Y.) (14.06.2024)
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Testing the effects of the GLP-1 receptor agonist exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder
Angarita, Gustavo A., Matuskey, David, Pittman, Brian, Costeines, Jessica L., Potenza, Marc N., Jastreboff, Ania M., Schmidt, Heath D., Malison, Robert T.
Published in Drug and alcohol dependence (01.04.2021)
Published in Drug and alcohol dependence (01.04.2021)
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Occurrence of Gastrointestinal Adverse Events Upon GLP-1 Receptor Agonist Initiation With Concomitant Metformin Use: A Post Hoc Analysis of LEADER, STEP 2, SUSTAIN-6, and PIONEER 6
Klein, Klara R., Clemmensen, Kim K.B., Fong, Edwin, Olsen, Søren, Abrahamsen, Trine, Lingvay, Ildiko
Published in Diabetes care (01.02.2024)
Published in Diabetes care (01.02.2024)
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Effects of Renal Impairment on the Pharmacokinetics of the Dual GIP and GLP-1 Receptor Agonist Tirzepatide
Urva, Shweta, Quinlan, Tonya, Landry, John, Martin, Jennifer, Loghin, Corina
Published in Clinical pharmacokinetics (01.08.2021)
Published in Clinical pharmacokinetics (01.08.2021)
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58-OR: The Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide Transiently Delays Gastric Emptying Similarly to a Selective Long-Acting GLP-1 Receptor Agonist
URVA, SHWETA, NAUCK, MICHAEL A., COSKUN, TAMER, CUI, XUEWEI, HAUPT, AXEL, BENSON, CHARLES, LOGHIN, CORINA
Published in Diabetes (New York, N.Y.) (01.06.2019)
Published in Diabetes (New York, N.Y.) (01.06.2019)
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769-P: Effect of Food on the Pharmacokinetics, Safety, and Tolerability of Orforglipron (LY3502970), an Oral, Nonpeptide GLP-1 Receptor Agonist
MA, XIAOSU, LIU, RONG, PRATT, EDWARD J., BENSON, CHARLES, BHATTACHAR, SHOBHA N.
Published in Diabetes (New York, N.Y.) (20.06.2023)
Published in Diabetes (New York, N.Y.) (20.06.2023)
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Effects of DPP‐4 inhibitor linagliptin and GLP‐1 receptor agonist liraglutide on physiological response to hypoglycaemia in Japanese subjects with type 2 diabetes: A randomized, open‐label, 2‐arm parallel comparative, exploratory trial
Yabe, Daisuke, Eto, Takashi, Shiramoto, Masanari, Irie, Shin, Murotani, Kenta, Seino, Yusuke, Kuwata, Hitoshi, Kurose, Takeshi, Seino, Susumu, Ahrén, Bo, Seino, Yutaka
Published in Diabetes, obesity & metabolism (01.03.2017)
Published in Diabetes, obesity & metabolism (01.03.2017)
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