Antihypertensive treatment guided by genetics: PEARL-HT, the randomized proof-of-concept trial comparing rostafuroxin with losartan
Citterio, Lorena, Bianchi, Giuseppe, Scioli, Giuseppe A., Glorioso, Nicola, Bigazzi, Roberto, Cusi, Daniele, Staessen, Jan A., Cavuto, Silvio, Ferrandi, Mara, Lanzani, Chiara, Li, Xiaoyi, Lau, Lit-Fui, Chiang, Chern-En, Wang, Tzung-Dau, Wang, Kang-Ling, Ferrari, Patrizia, Manunta, Paolo
Published in The pharmacogenomics journal (01.06.2021)
Published in The pharmacogenomics journal (01.06.2021)
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An overview of the genetic structure within the Italian population from genome-wide data
Di Gaetano, Cornelia, Voglino, Floriana, Guarrera, Simonetta, Fiorito, Giovanni, Rosa, Fabio, Di Blasio, Anna Maria, Manzini, Paola, Dianzani, Irma, Betti, Marta, Cusi, Daniele, Frau, Francesca, Barlassina, Cristina, Mirabelli, Dario, Magnani, Corrado, Glorioso, Nicola, Bonassi, Stefano, Piazza, Alberto, Matullo, Giuseppe
Published in PloS one (12.09.2012)
Published in PloS one (12.09.2012)
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Sardinians genetic background explained by runs of homozygosity and genomic regions under positive selection
Di Gaetano, Cornelia, Fiorito, Giovanni, Ortu, Maria Francesca, Rosa, Fabio, Guarrera, Simonetta, Pardini, Barbara, Cusi, Daniele, Frau, Francesca, Barlassina, Cristina, Troffa, Chiara, Argiolas, Giuseppe, Zaninello, Roberta, Fresu, Giovanni, Glorioso, Nicola, Piazza, Alberto, Matullo, Giuseppe
Published in PloS one (20.03.2014)
Published in PloS one (20.03.2014)
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Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)
Singh, Sonal, Warren, Helen R, Hiltunen, Timo P, McDonough, Caitrin W, El Rouby, Nihal, Salvi, Erika, Wang, Zhiying, Garofalidou, Tatiana, Fyhrquist, Frej, Kontula, Kimmo K, Glorioso, Valeria, Zaninello, Roberta, Glorioso, Nicola, Pepine, Carl J, Munroe, Patricia B, Turner, Stephan T, Chapman, Arlene B, Boerwinkle, Eric, Johnson, Julie A, Gong, Yan, Cooper-DeHoff, Rhonda M
Published in Journal of the American Heart Association (20.08.2019)
Published in Journal of the American Heart Association (20.08.2019)
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Dissecting the Polygenic Basis of Primary Hypertension: Identification of Key Pathway-Specific Components
Maj, Carlo, Salvi, Erika, Citterio, Lorena, Borisov, Oleg, Simonini, Marco, Glorioso, Valeria, Barlassina, Cristina, Glorioso, Nicola, Thijs, Lutgarde, Kuznetsova, Tatiana, Cappuccio, Francesco P, Zhang, Zhen-Yu, Staessen, Jan A, Cusi, Daniele, Lanzani, Chiara, Manunta, Paolo
Published in Frontiers in cardiovascular medicine (16.02.2022)
Published in Frontiers in cardiovascular medicine (16.02.2022)
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Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies
Lanzani, Chiara, Citterio, Lorena, Glorioso, Nicola, Manunta, Paolo, Tripodi, Grazia, Salvi, Erika, Carpini, Simona Delli, Ferrandi, Mara, Messaggio, Elisabetta, Staessen, Jan A, Cusi, Daniele, Macciardi, Fabio, Argiolas, Giuseppe, Valentini, Giovanni, Ferrari, Patrizia, Bianchi, Giuseppe
Published in Science translational medicine (24.11.2010)
Published in Science translational medicine (24.11.2010)
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Sex-specific effects of NLRP6/AVR and ADM loci on susceptibility to essential hypertension in a Sardinian population
Glorioso, Nicola, Herrera, Victoria L, Didishvili, Tamara, Ortu, Maria F, Zaninello, Roberta, Fresu, Giovanni, Argiolas, Guiseppe, Troffa, Chiara, Ruiz-Opazo, Nelson
Published in PloS one (11.10.2013)
Published in PloS one (11.10.2013)
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A functional 12T-insertion polymorphism in the ATP1A1 promoter confers decreased susceptibility to hypertension in a male Sardinian population
Herrera, Victoria L, Pasion, Khristine A, Moran, Ann Marie, Zaninello, Roberta, Ortu, Maria Francesca, Fresu, Giovanni, Piras, Daniela Antonella, Argiolas, Giuseppe, Troffa, Chiara, Glorioso, Valeria, Masala, Wanda, Glorioso, Nicola, Ruiz-Opazo, Nelson
Published in PloS one (23.01.2015)
Published in PloS one (23.01.2015)
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Antihypertensive efficacy and tolerability of aliskiren/amlodipine single- pill combinations in patients with an inadequate response to aliskiren monotherapy
Glorioso, Nicola, Thomas, Mathew, Troffa, Chiara, Argiolas, Giuseppe, Patel, Samir, Baek, Inyoung, Zhang, Jack
Published in Current vascular pharmacology (01.11.2012)
Published in Current vascular pharmacology (01.11.2012)
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Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin
Staessen, Jan A, Thijs, Lutgarde, Stolarz-Skrzypek, Katarzyna, Bacchieri, Antonella, Barton, John, Espositi, Ezio Degli, de Leeuw, Peter W, Dłużniewski, Mirosław, Glorioso, Nicola, Januszewicz, Andrzej, Manunta, Paolo, Milyagin, Viktor, Nikitin, Yuri, Souček, Miroslav, Lanzani, Chiara, Citterio, Lorena, Timio, Mario, Tykarski, Andrzej, Ferrari, Patrizia, Valentini, Giovanni, Kawecka-Jaszcz, Kalina, Bianchi, Giuseppe
Published in Current controlled trials in cardiovascular medicine (14.01.2011)
Published in Current controlled trials in cardiovascular medicine (14.01.2011)
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Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH: a clinical and molecular genetic analysis
Arca, Marcello, Zuliani, Giovanni, Wilund, Kenneth, Campagna, Filomena, Fellin, Renato, Bertolini, Stefano, Calandra, Sebastiano, Ricci, Giorgio, Glorioso, Nicola, Maioli, Mario, Pintus, Paolo, Carru, Ciriaco, Cossu, Fausto, Cohen, Jonathan, Hobbs, Helen H
Published in The Lancet (British edition) (09.03.2002)
Published in The Lancet (British edition) (09.03.2002)
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Kallikrein-Kinin System and Blood Pressure Sensitivity to Salt
Madeddu, Paolo, Varoni, Maria Vittoria, Demontis, Maria Piera, Chao, Julie, Simson, Jo Anne, Glorioso, Nicola, Anania, Vittorio
Published in Hypertension (Dallas, Tex. 1979) (01.01.1997)
Published in Hypertension (Dallas, Tex. 1979) (01.01.1997)
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Conference Proceeding
Genomewide Association Study Using a High-Density Single Nucleotide Polymorphism Array and Case-Control Design Identifies a Novel Essential Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Synthase
Salvi, Erika, Kutalik, Zoltán, Glorioso, Nicola, Benaglio, Paola, Frau, Francesca, Kuznetsova, Tatiana, Arima, Hisatomi, Hoggart, Clive, Tichet, Jean, Nikitin, Yury P, Conti, Costanza, Seidlerova, Jitka, Tikhonoff, Valérie, Stolarz-Skrzypek, Katarzyna, Johnson, Toby, Devos, Nabila, Zagato, Laura, Guarrera, Simonetta, Zaninello, Roberta, Calabria, Andrea, Stancanelli, Benedetta, Troffa, Chiara, Thijs, Lutgarde, Rizzi, Federica, Simonova, Galina, Lupoli, Sara, Argiolas, Giuseppe, Braga, Daniele, DʼAlessio, Maria C, Ortu, Maria F, Ricceri, Fulvio, Mercurio, Maurizio, Descombes, Patrick, Marconi, Maurizio, Chalmers, John, Harrap, Stephen, Filipovsky, Jan, Bochud, Murielle, Iacoviello, Licia, Ellis, Justine, Stanton, Alice V, Laan, Maris, Padmanabhan, Sandosh, Dominiczak, Anna F, Samani, Nilesh J, Melander, Olle, Jeunemaitre, Xavier, Manunta, Paolo, Shabo, Amnon, Vineis, Paolo, Cappuccio, Francesco P, Caulfield, Mark J, Matullo, Giuseppe, Rivolta, Carlo, Munroe, Patricia B, Barlassina, Cristina, Staessen, Jan A, Beckmann, Jacques S, Cusi, Daniele
Published in Hypertension (Dallas, Tex. 1979) (01.02.2012)
Published in Hypertension (Dallas, Tex. 1979) (01.02.2012)
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A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia
Ferrari, Raffaele, Grassi, Mario, Salvi, Erika, Borroni, Barbara, Palluzzi, Fernando, Pepe, Daniele, D'Avila, Francesca, Padovani, Alessandro, Archetti, Silvana, Rainero, Innocenzo, Rubino, Elisa, Pinessi, Lorenzo, Benussi, Luisa, Binetti, Giuliano, Ghidoni, Roberta, Galimberti, Daniela, Scarpini, Elio, Serpente, Maria, Rossi, Giacomina, Giaccone, Giorgio, Tagliavini, Fabrizio, Nacmias, Benedetta, Piaceri, Irene, Bagnoli, Silvia, Bruni, Amalia C, Maletta, Raffaele G, Bernardi, Livia, Postiglione, Alfredo, Milan, Graziella, Franceschi, Massimo, Puca, Annibale A, Novelli, Valeria, Barlassina, Cristina, Glorioso, Nicola, Manunta, Paolo, Singleton, Andrew, Cusi, Daniele, Hardy, John, Momeni, Parastoo
Published in Neurobiology of aging (01.10.2015)
Published in Neurobiology of aging (01.10.2015)
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Early Blockade of Bradykinin B2 -Receptors Alters the Adult Cardiovascular Phenotype in Rats
Madeddu, Paolo, Parpaglia, Paolo Pinna, Demontis, Maria Piera, Varoni, Maria Vittoria, Fattaccio, Maria Caterina, Anania, Vittorio, Glorioso, Nicola
Published in Hypertension (Dallas, Tex. 1979) (01.03.1995)
Published in Hypertension (Dallas, Tex. 1979) (01.03.1995)
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Adverse Cardiovascular Outcomes and Antihypertensive Treatment: A Genome-Wide Interaction Meta-Analysis in the International Consortium for Antihypertensive Pharmacogenomics Studies
McDonough, Caitrin W, Warren, Helen R, Jack, John R, Motsinger-Reif, Alison A, Armstrong, Nicole D, Bis, Joshua C, House, John S, Singh, Sonal, El Rouby, Nihal M, Gong, Yan, Mychaleckyj, Joesyf C, Rotroff, Daniel M, Benavente, Oscar R, Caulfield, Mark J, Doria, Alessandrio, Pepine, Carl J, Psaty, Bruce M, Glorioso, Valeria, Glorioso, Nicola, Hiltunen, Timo P, Kontula, Kimmo K, Arnett, Donna K, Buse, John B, Irvin, Marguerite R, Johnson, Julie A, Munroe, Patricia B, Wagner, Michael J, Cooper-DeHoff, Rhonda M
Published in Clinical pharmacology and therapeutics (01.09.2021)
Published in Clinical pharmacology and therapeutics (01.09.2021)
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Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide
Salvi, Erika, Wang, Zhiying, Rizzi, Federica, Gong, Yan, McDonough, Caitrin W, Padmanabhan, Sandosh, Hiltunen, Timo P, Lanzani, Chiara, Zaninello, Roberta, Chittani, Martina, Bailey, Kent R, Sarin, Antti-Pekka, Barcella, Matteo, Melander, Olle, Chapman, Arlene B, Manunta, Paolo, Kontula, Kimmo K, Glorioso, Nicola, Cusi, Daniele, Dominiczak, Anna F, Johnson, Julie A, Barlassina, Cristina, Boerwinkle, Eric, Cooper-DeHoff, Rhonda M, Turner, Stephen T
Published in Hypertension (Dallas, Tex. 1979) (01.01.2017)
Published in Hypertension (Dallas, Tex. 1979) (01.01.2017)
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Antisense Inhibition of the Brain Kallikrein-Kinin System
Madeddu, Paolo, Parpaglia, Paolo Pinna, Glorioso, Nicola, Chao, Lee, Chao, Julie
Published in Hypertension (Dallas, Tex. 1979) (01.12.1996)
Published in Hypertension (Dallas, Tex. 1979) (01.12.1996)
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Conference Proceeding
Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs
Hiltunen, Timo P, Donner, Kati M, Sarin, Antti-Pekka, Saarela, Janna, Ripatti, Samuli, Chapman, Arlene B, Gums, John G, Gong, Yan, Cooper-DeHoff, Rhonda M, Frau, Francesca, Glorioso, Valeria, Zaninello, Roberta, Salvi, Erika, Glorioso, Nicola, Boerwinkle, Eric, Turner, Stephen T, Johnson, Julie A, Kontula, Kimmo K
Published in Journal of the American Heart Association (01.01.2015)
Published in Journal of the American Heart Association (01.01.2015)
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