Practice-based evidence can help! Using the Group Questionnaire to enhance clinical practice
Griner, Derek, Beecher, Mark E, Brown, Loren B, Millet, Austin J, Worthen, Vaughn, Boardman, R D, Hansen, Kristina, Cox, Jonathan C, Gleave, Robert L
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Published in Psychotherapy (Chicago, Ill.) (01.06.2018)
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Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor
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Published in Bioorganic & medicinal chemistry letters (01.09.2010)
Published in Bioorganic & medicinal chemistry letters (01.09.2010)
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Synthesis and biological activity of a series of tetrasubstituted-imidazoles as P2X7 antagonists
GLEAVE, Robert J, WALTER, Daryl S, BESWICK, Paul J, FONFRIA, Elena, MICHEL, Anton D, ROMAN, Shilina A, TANG, Sac-Pham
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Synthesis and biological activity of a series of tetrasubstituted-imidazoles as P2X(7) antagonists
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Published in Bioorganic & medicinal chemistry letters (15.08.2010)
Published in Bioorganic & medicinal chemistry letters (15.08.2010)
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Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X(7) receptor
Abberley, Lee, Bebius, Aude, Beswick, Paul J, Billinton, Andy, Collis, Katharine L, Dean, David K, Fonfria, Elena, Gleave, Robert J, Medhurst, Stephen J, Michel, Anton D, Moses, Andrew P, Patel, Sadhana, Roman, Shilina A, Scoccitti, Tiziana, Smith, Beverley, Steadman, Jon G A, Walter, Daryl S
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB2 agonists for the treatment of inflammatory pain
GLEAVE, Robert J, BESWICK, Paul J, ROOMANS, Susan, SLINGSBY, Brian P, SWARBRICK, Martin E, BROWN, Andrew J, GIBLIN, Gerard M. P, GOLDSMITH, Paul, HASLAM, Carl P, MITCHELL, William L, NICHOLSON, Neville H, PAGE, Lee W, PATEL, Sadhana
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
Published in Bioorganic & medicinal chemistry letters (15.01.2010)
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Journal Article
Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X7 receptor
Abberley, Lee, Bebius, Aude, Beswick, Paul J., Billinton, Andy, Collis, Katharine L., Dean, David K., Fonfria, Elena, Gleave, Robert J., Medhurst, Stephen J., Michel, Anton D., Moses, Andrew P., Patel, Sadhana, Roman, Shilina A., Scoccitti, Tiziana, Smith, Beverley, Steadman, Jon G.A., Walter, Daryl S.
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X(7) receptor
Beswick, Paul J, Billinton, Andy, Chambers, Laura J, Dean, David K, Fonfria, Elena, Gleave, Robert J, Medhurst, Stephen J, Michel, Anton D, Moses, Andrew P, Patel, Sadhana, Roman, Shilina A, Roomans, Sue, Senger, Stefan, Stevens, Alexander J, Walter, Daryl S
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Journal Article
Synthesis and structure-activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor
CHAMBERS, Laura J, STEVENS, Alexander J, THEOBALD, Pam J, BESWICK, Paul J, GLEAVE, Robert J, ROMAN, Shilina A, SENGER, Stefan, MOSES, Andrew P, MICHEL, Anton D, WALTER, Daryl S, DAVIES, David J, LIVERMORE, David G, FONFRIA, Elena, DEMONT, Emmanuel H, VIMAL, Mythily
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
Published in Bioorganic & medicinal chemistry letters (15.05.2010)
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Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach
Beswick, Paul J., Blackaby, Andrew P., Bountra, Chas, Brown, Terry, Browning, Kerry, Campbell, Ian B., Corfield, John, Gleave, Robert J., Guntrip, Steve B., Hall, Richard M., Hindley, Sean, Lambeth, Paul F., Lucas, Fiona, Mathews, Neil, Naylor, Alan, Player, Hazel, Price, Helen S., Sidebottom, Phillip J., Taylor, Nicholas L., Webb, Graham, Wiseman, Joanne
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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2-Amino-5-aryl-pyridines as selective CB2 agonists: Synthesis and investigation of structure-activity relationships
GLEAVE, Robert J, BESWICK, Paul J, SWARBRICK, Martin E, BROWN, Andrew J, GIBLIN, Gerard M. P, HASLAM, Carl P, LIVERMORE, David, MOSES, Andrew, NICHOLSON, Neville H, PAGE, Lee W, SLINGSBY, Brian
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
Published in Bioorganic & medicinal chemistry letters (01.12.2009)
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Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors
Swarbrick, Martin E., Beswick, Paul J., Gleave, Robert J., Green, Richard H., Bingham, Sharon, Bountra, Chas, Carter, Malcolm C., Chambers, Laura J., Chessell, Iain P., Clayton, Nick M., Collins, Sue D., Corfield, John A., Hartley, C. David, Kleanthous, Savvas, Lambeth, Paul F., Lucas, Fiona S., Mathews, Neil, Naylor, Alan, Page, Lee W., Payne, Jeremy J., Pegg, Neil A., Price, Helen S., Skidmore, John, Stevens, Alexander J., Stocker, Richard, Stratton, Sharon C., Stuart, Alastair J., Wiseman, Joanne O.
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Structure-activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists
HALL, Adrian, ATKINSON, Stephen, HEALY, Mark P, JOHNSON, Matthew R, MICHEL, Anton D, NAYLOR, Alan, NOVELLI, Riccardo, SPALDING, David J, TANG, Sac P, BROWN, Susan H, CHESSELL, Iain P, CHOWDHURY, Anita, CLAYTON, Nicholas M, COLEMAN, Tanya, GIBLIN, Gerard M. P, GLEAVE, Robert J, HAMMOND, Beverley
Published in Bioorganic & medicinal chemistry letters (15.07.2006)
Published in Bioorganic & medicinal chemistry letters (15.07.2006)
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Journal Article
Structure–activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor
Beswick, Paul J., Billinton, Andy, Chambers, Laura J., Dean, David K., Fonfria, Elena, Gleave, Robert J., Medhurst, Stephen J., Michel, Anton D., Moses, Andrew P., Patel, Sadhana, Roman, Shilina A., Roomans, Sue, Senger, Stefan, Stevens, Alexander J., Walter, Daryl S.
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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