Ion Channels as a Therapeutic Target: Drug Design and Pharmacological Investigation
Guerrini, Gabriella, Giovannoni, Maria Paola
Published in International journal of molecular sciences (22.12.2023)
Published in International journal of molecular sciences (22.12.2023)
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Journal Article
An Overview of PDE4 Inhibitors in Clinical Trials: 2010 to Early 2022
Crocetti, Letizia, Floresta, Giuseppe, Cilibrizzi, Agostino, Giovannoni, Maria Paola
Published in Molecules (Basel, Switzerland) (04.08.2022)
Published in Molecules (Basel, Switzerland) (04.08.2022)
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4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABAA Receptor Subtype
Crocetti, Letizia, Guerrini, Gabriella, Melani, Fabrizio, Vergelli, Claudia, Giovannoni, Maria Paola
Published in Molecules (Basel, Switzerland) (29.03.2023)
Published in Molecules (Basel, Switzerland) (29.03.2023)
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Journal Article
GABAA Receptor Modulators with a Pyrazolo[1,5-a]quinazoline Core: Synthesis, Molecular Modelling Studies and Electrophysiological Assays
Crocetti, Letizia, Guerrini, Gabriella, Melani, Fabrizio, Vergelli, Claudia, Mascia, Maria Paola, Giovannoni, Maria Paola
Published in International journal of molecular sciences (27.10.2022)
Published in International journal of molecular sciences (27.10.2022)
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Journal Article
New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies
Crocetti, Letizia, Guerrini, Gabriella, Giovannoni, Maria Paola, Melani, Fabrizio, Lamanna, Silvia, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Ghelardini, Carla, Wang, Junjie, Dahl, Gerhard
Published in International journal of molecular sciences (27.04.2022)
Published in International journal of molecular sciences (27.04.2022)
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Journal Article
Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers
Crocetti, Letizia, Giovannoni, Maria Paola, Guerrini, Gabriella, Lamanna, Silvia, Melani, Fabrizio, Bartolucci, Gianluca, Pallecchi, Marco, Paoli, Paola, Lippi, Martina, Wang, Junjie, Dahl, Gerhard
Published in International journal of molecular sciences (19.01.2023)
Published in International journal of molecular sciences (19.01.2023)
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Journal Article
Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity
Cantini, Niccolo, Schepetkin, Igor A., Danilenko, Nadezhda V., Khlebnikov, Andrei I., Crocetti, Letizia, Giovannoni, Maria Paola, Kirpotina, Liliya N., Quinn, Mark T.
Published in Molecules (Basel, Switzerland) (10.06.2022)
Published in Molecules (Basel, Switzerland) (10.06.2022)
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Journal Article
1H-pyrrolo[2,3-b]pyridine: A new scaffold for human neutrophil elastase (HNE) inhibitors
Crocetti, Letizia, Giovannoni, Maria Paola, Schepetkin, Igor A., Quinn, Mark T., Khlebnikov, Andrei I., Cantini, Niccolò, Guerrini, Gabriella, Iacovone, Antonella, Teodori, Elisabetta, Vergelli, Claudia
Published in Bioorganic & medicinal chemistry (15.11.2018)
Published in Bioorganic & medicinal chemistry (15.11.2018)
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Journal Article
iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer
Cilibrizzi, Agostino, Floresta, Giuseppe, Abbate, Vincenzo, Giovannoni, Maria Paola
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
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Journal Article
Repurposing strategies on pyridazinone-based series by pharmacophore- and structure-driven screening
Floresta, Giuseppe, Crocetti, Letizia, Giovannoni, Maria Paola, Biagini, Pierfrancesco, Cilibrizzi, Agostino
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Journal Article
Pyridinone Derivatives as Interesting Formyl Peptide Receptor (FPR) Agonists for the Treatment of Rheumatoid Arthritis
Crocetti, Letizia, Vergelli, Claudia, Guerrini, Gabriella, Giovannoni, Maria Paola, Kirpotina, Liliya N, Khlebnikov, Andrei I, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Schepetkin, Igor A, Quinn, Mark T
Published in Molecules (Basel, Switzerland) (30.10.2021)
Published in Molecules (Basel, Switzerland) (30.10.2021)
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Journal Article
Optimization of N‑Benzoylindazole Derivatives as Inhibitors of Human Neutrophil Elastase
Crocetti, Letizia, Schepetkin, Igor A, Cilibrizzi, Agostino, Graziano, Alessia, Vergelli, Claudia, Giomi, Donatella, Khlebnikov, Andrei I, Quinn, Mark T, Giovannoni, Maria Paola
Published in Journal of medicinal chemistry (08.08.2013)
Published in Journal of medicinal chemistry (08.08.2013)
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Journal Article
Effects of the neutrophil elastase inhibitor EL-17 in rat adjuvant-induced arthritis
Di Cesare Mannelli, Lorenzo, Micheli, Laura, Cinci, Lorenzo, Maresca, Mario, Vergelli, Claudia, Pacini, Alessandra, Quinn, Mark T, Paola Giovannoni, Maria, Ghelardini, Carla
Published in Rheumatology (Oxford, England) (01.07.2016)
Published in Rheumatology (Oxford, England) (01.07.2016)
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Journal Article
Ligand Growing Experiments Suggested 4-amino and 4-ureido pyridazin-3(2H)-one as Novel Scaffold for FABP4 Inhibition
Crocetti, Letizia, Floresta, Giuseppe, Zagni, Chiara, Merugu, Divya, Mazzacuva, Francesca, de Oliveira Silva, Renan Rodrigues, Vergelli, Claudia, Giovannoni, Maria Paola, Cilibrizzi, Agostino
Published in Pharmaceuticals (Basel, Switzerland) (28.10.2022)
Published in Pharmaceuticals (Basel, Switzerland) (28.10.2022)
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Journal Article
Editorial: Serine protease inhibitors and their therapeutic applications
Crocetti, Letizia, Quinn, Mark T., Cilibrizzi, Agostino, Giovannoni, Maria Paola
Published in Frontiers in chemistry (08.08.2022)
Published in Frontiers in chemistry (08.08.2022)
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Journal Article
Synthesis of New GABAA Receptor Modulator with Pyrazolo[1,5-a]quinazoline (PQ) Scaffold
Guerrini, Gabriella, Vergelli, Claudia, Cantini, Niccolò, Giovannoni, Maria, Daniele, Simona, Mascia, Maria, Martini, Claudia, Crocetti, Letizia
Published in International journal of molecular sciences (21.03.2019)
Published in International journal of molecular sciences (21.03.2019)
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Journal Article
Isoxazol-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors
Vergelli, Claudia, Schepetkin, Igor A., Crocetti, Letizia, Iacovone, Antonella, Giovannoni, Maria Paola, Guerrini, Gabriella, Khlebnikov, Andrei I., Ciattini, Samuele, Ciciani, Giovanna, Quinn, Mark T.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2017)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2017)
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Journal Article
Synthesis, biological evaluation, and molecular modelling studies of potent human neutrophil elastase (HNE) inhibitors
Giovannoni, Maria Paola, Schepetkin, Igor A., Quinn, Mark T., Cantini, Niccolò, Crocetti, Letizia, Guerrini, Gabriella, Iacovone, Antonella, Paoli, Paola, Rossi, Patrizia, Bartolucci, Gianluca, Menicatti, Marta, Vergelli, Claudia
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)
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Journal Article