Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol
Jackson, Meredith A, Werfel, Thomas A, Curvino, Elizabeth J, Yu, Fang, Kavanaugh, Taylor E, Sarett, Samantha M, Dockery, Mary D, Kilchrist, Kameron V, Jackson, Ayisha N, Giorgio, Todd D, Duvall, Craig L
Published in ACS nano (27.06.2017)
Published in ACS nano (27.06.2017)
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Journal Article
Ex vivo red blood cell hemolysis assay for the evaluation of pH-responsive endosomolytic agents for cytosolic delivery of biomacromolecular drugs
Evans, Brian C, Nelson, Christopher E, Yu, Shann S, Beavers, Kelsey R, Kim, Arnold J, Li, Hongmei, Nelson, Heather M, Giorgio, Todd D, Duvall, Craig L
Published in Journal of visualized experiments (09.03.2013)
Published in Journal of visualized experiments (09.03.2013)
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Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers
Miteva, Martina, Kirkbride, Kellye C, Kilchrist, Kameron V, Werfel, Thomas A, Li, Hongmei, Nelson, Christopher E, Gupta, Mukesh K, Giorgio, Todd D, Duvall, Craig L
Published in Biomaterials (01.01.2015)
Published in Biomaterials (01.01.2015)
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Journal Article
Matrix Metalloproteinase Responsive, Proximity-Activated Polymeric Nanoparticles for siRNA Delivery
Li, Hongmei, Yu, Shann S., Miteva, Martina, Nelson, Christopher E., Werfel, Thomas, Giorgio, Todd D., Duvall, Craig L.
Published in Advanced functional materials (25.06.2013)
Published in Advanced functional materials (25.06.2013)
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Journal Article
Combination immunotherapy and radiotherapy causes an abscopal treatment response in a mouse model of castration resistant prostate cancer
Dudzinski, Stephanie O, Cameron, Brent D, Wang, Jian, Rathmell, Jeffrey C, Giorgio, Todd D, Kirschner, Austin N
Published in Journal for immunotherapy of cancer (14.08.2019)
Published in Journal for immunotherapy of cancer (14.08.2019)
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Journal Article
Biocompatible mannosylated endosomal-escape nanoparticles enhance selective delivery of short nucleotide sequences to tumor associated macrophages
Ortega, Ryan A, Barham, Whitney J, Kumar, Bharat, Tikhomirov, Oleg, McFadden, Ian D, Yull, Fiona E, Giorgio, Todd D
Published in Nanoscale (14.01.2015)
Published in Nanoscale (14.01.2015)
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Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer
Hoover, Alyssa A, Hufnagel, Demetra H, Harris, Whitney, Bullock, Kennady, Glass, Evan B, Liu, Esther, Barham, Whitney, Crispens, Marta A, Khabele, Dineo, Giorgio, Todd D, Wilson, Andrew J, Yull, Fiona E
Published in BMC cancer (07.10.2020)
Published in BMC cancer (07.10.2020)
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Macrophage-Specific RNA Interference Targeting via “Click”, Mannosylated Polymeric Micelles
Yu, Shann S, Lau, Cheryl M, Barham, Whitney J, Onishko, Halina M, Nelson, Christopher E, Li, Hongmei, Smith, Chelsey A, Yull, Fiona E, Duvall, Craig L, Giorgio, Todd D
Published in Molecular pharmaceutics (04.03.2013)
Published in Molecular pharmaceutics (04.03.2013)
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Journal Article
Dual MMP7-Proximity-Activated and Folate Receptor-Targeted Nanoparticles for siRNA Delivery
Li, Hongmei, Miteva, Martina, Kirkbride, Kellye C, Cheng, Ming J, Nelson, Christopher E, Simpson, Elaine M, Gupta, Mukesh K, Duvall, Craig L, Giorgio, Todd D
Published in Biomacromolecules (12.01.2015)
Published in Biomacromolecules (12.01.2015)
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Stimulating TAM-mediated anti-tumor immunity with mannose-decorated nanoparticles in ovarian cancer
Glass, Evan B, Hoover, Alyssa A, Bullock, Kennady K, Madden, Matthew Z, Reinfeld, Bradley I, Harris, Whitney, Parker, Dominique, Hufnagel, Demetra H, Crispens, Marta A, Khabele, Dineo, Rathmell, W Kimryn, Rathmell, Jeffrey C, Wilson, Andrew J, Giorgio, Todd D, Yull, Fiona E
Published in BMC cancer (06.05.2022)
Published in BMC cancer (06.05.2022)
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Dynamic Computational Model of Symptomatic Bacteremia to Inform Bacterial Separation Treatment Requirements
Miller, Sinead E, Bell, Charleson S, McClain, Mark S, Cover, Timothy L, Giorgio, Todd D
Published in PloS one (01.09.2016)
Published in PloS one (01.09.2016)
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Journal Article
Optimizing Mannose “Click” Conjugation to Polymeric Nanoparticles for Targeted siRNA Delivery to Human and Murine Macrophages
Glass, Evan B, Masjedi, Shirin, Dudzinski, Stephanie O, Wilson, Andrew J, Duvall, Craig L, Yull, Fiona E, Giorgio, Todd D
Published in ACS omega (15.10.2019)
Published in ACS omega (15.10.2019)
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Combinatorial polymer electrospun matrices promote physiologically-relevant cardiomyogenic stem cell differentiation
Gupta, Mukesh K, Walthall, Joel M, Venkataraman, Raghav, Crowder, Spencer W, Jung, Dae Kwang, Yu, Shann S, Feaster, Tromondae K, Wang, Xintong, Giorgio, Todd D, Hong, Charles C, Baudenbacher, Franz J, Hatzopoulos, Antonis K, Sung, Hak-Joon
Published in PloS one (27.12.2011)
Published in PloS one (27.12.2011)
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The Multistrata Nanoparticle: an FeOx/Au Core/Shell Enveloped in a Silica-Au Shell
Bell, Charleson S., Yu, Shann S., Giorgio, Todd D.
Published in Small (Weinheim an der Bergstrasse, Germany) (09.05.2011)
Published in Small (Weinheim an der Bergstrasse, Germany) (09.05.2011)
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Journal Article
Olfactory receptor gene abundance in invasive breast carcinoma
Masjedi, Shirin, Zwiebel, Laurence J., Giorgio, Todd D.
Published in Scientific reports (24.09.2019)
Published in Scientific reports (24.09.2019)
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Journal Article
Superparamagnetic Nanoparticles as a Powerful Systems Biology Characterization Tool in the Physiological Context
Salaklang, Jatuporn, Steitz, Benedikt, Finka, Andrija, O'Neil, Conlin P, Moniatte, Marc, van der Vlies, André J, Giorgio, Todd D, Hofmann, Heinrich, Hubbell, Jeffrey A, Petri-Fink, Alke
Published in Angewandte Chemie (International ed.) (29.09.2008)
Published in Angewandte Chemie (International ed.) (29.09.2008)
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Leptin Augments Antitumor Immunity in Obesity by Repolarizing Tumor-Associated Macrophages
Dudzinski, Stephanie O, Bader, Jackie E, Beckermann, Kathryn E, Young, Kirsten L, Hongo, Rachel, Madden, Matthew Z, Abraham, Abin, Reinfeld, Bradley I, Ye, Xiang, MacIver, Nancie J, Giorgio, Todd D, Rathmell, Jeffrey C
Published in The Journal of immunology (1950) (15.12.2021)
Published in The Journal of immunology (1950) (15.12.2021)
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Journal Article
Combinatorial optimization of PEG architecture and hydrophobic content improves ternary siRNA polyplex stability, pharmacokinetics, and potency in vivo
Werfel, Thomas A., Jackson, Meredith A., Kavanaugh, Taylor E., Kirkbride, Kellye C., Miteva, Martina, Giorgio, Todd D., Duvall, Craig
Published in Journal of controlled release (10.06.2017)
Published in Journal of controlled release (10.06.2017)
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