Apoptosis-inducing factor: vital and lethal
Modjtahedi, Nazanine, Giordanetto, Fabrizio, Madeo, Frank, Kroemer, Guido
Published in Trends in cell biology (01.05.2006)
Published in Trends in cell biology (01.05.2006)
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Journal Article
Structural basis of AMPK regulation by small molecule activators
Xiao, Bing, Sanders, Matthew J., Carmena, David, Bright, Nicola J., Haire, Lesley F., Underwood, Elizabeth, Patel, Bhakti R., Heath, Richard B., Walker, Philip A., Hallen, Stefan, Giordanetto, Fabrizio, Martin, Stephen R., Carling, David, Gamblin, Steven J.
Published in Nature communications (19.12.2013)
Published in Nature communications (19.12.2013)
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Journal Article
Stabilization of protein–protein interactions by small molecules
Giordanetto, Fabrizio, Schäfer, Anja, Ottmann, Christian
Published in Drug discovery today (01.11.2014)
Published in Drug discovery today (01.11.2014)
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Journal Article
Expansion of chemical space for collaborative lead generation and drug discovery: the European Lead Factory Perspective
Karawajczyk, Anna, Giordanetto, Fabrizio, Benningshof, Jorg, Hamza, Daniel, Kalliokoski, Tuomo, Pouwer, Kees, Morgentin, Remy, Nelson, Adam, Müller, Gerhard, Piechot, Alexander, Tzalis, Dimitrios
Published in Drug discovery today (01.11.2015)
Published in Drug discovery today (01.11.2015)
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Journal Article
High-Throughput Screening of Drug−Brain Tissue Binding and in Silico Prediction for Assessment of Central Nervous System Drug Delivery
Wan, Hong, Rehngren, Mikael, Giordanetto, Fabrizio, Bergström, Fredrik, Tunek, Anders
Published in Journal of medicinal chemistry (20.09.2007)
Published in Journal of medicinal chemistry (20.09.2007)
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Journal Article
A Versatile Strategy for the Synthesis of 4,5-Dihydroxy-2,3-Pentanedione (DPD) and Related Compounds as Potential Modulators of Bacterial Quorum Sensing
Stotani, Silvia, Gatta, Viviana, Medda, Federico, Padmanaban, Mohan, Karawajczyk, Anna, Tammela, Päivi, Giordanetto, Fabrizio, Tzalis, Dimitrios, Collina, Simona
Published in Molecules (Basel, Switzerland) (06.10.2018)
Published in Molecules (Basel, Switzerland) (06.10.2018)
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Journal Article
Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties
Over, Björn, McCarren, Patrick, Artursson, Per, Foley, Michael, Giordanetto, Fabrizio, Grönberg, Gunnar, Hilgendorf, Constanze, Lee, Maurice D, Matsson, Pär, Muncipinto, Giovanni, Pellisson, Mélanie, Perry, Matthew W. D, Svensson, Richard, Duvall, Jeremy R, Kihlberg, Jan
Published in Journal of medicinal chemistry (27.03.2014)
Published in Journal of medicinal chemistry (27.03.2014)
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Journal Article
On Evaluating Molecular-Docking Methods for Pose Prediction and Enrichment Factors
Chen, Hongming, Lyne, Paul D, Giordanetto, Fabrizio, Lovell, Timothy, Li, Jin
Published in Journal of chemical information and modeling (01.01.2006)
Published in Journal of chemical information and modeling (01.01.2006)
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Journal Article
AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis
CANDE, Céline, VAHSEN, Nicola, PENNINGER, Josef M, KROEMER, Guido, KOURANTI, Ilektra, SCHMITT, Elise, DAUGAS, Eric, SPAHR, Chris, LUBAN, Jeremy, KROEMER, Romano T, GIORDANETTO, Fabrizio, GARRIDO, Carmen
Published in Oncogene (26.02.2004)
Published in Oncogene (26.02.2004)
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Journal Article
Structure-Based Discovery of Allosteric Modulators of Two Related Class B G-Protein-Coupled Receptors
de Graaf, Chris, Rein, Chantal, Piwnica, David, Giordanetto, Fabrizio, Rognan, Didier
Published in ChemMedChem (09.12.2011)
Published in ChemMedChem (09.12.2011)
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Journal Article
2‐Sulfonylpyrimidines Target the Kinesin HSET via Cysteine Alkylation
Förster, Tim, Shang, Erchang, Shimizu, Kenshiro, Sanada, Emiko, Schölermann, Beate, Huebecker, Mylene, Hahne, Gernot, López‐Alberca, Maria Pascual, Janning, Petra, Watanabe, Nobumoto, Sievers, Sonja, Giordanetto, Fabrizio, Shimizu, Takeshi, Ziegler, Slava, Osada, Hiroyuki, Waldmann, Herbert
Published in European journal of organic chemistry (01.09.2019)
Published in European journal of organic chemistry (01.09.2019)
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Journal Article
Discovery of AZD2716: A Novel Secreted Phospholipase A2 (sPLA2) Inhibitor for the Treatment of Coronary Artery Disease
Giordanetto, Fabrizio, Pettersen, Daniel, Starke, Ingemar, Nordberg, Peter, Dahlström, Mikael, Knerr, Laurent, Selmi, Nidhal, Rosengren, Birgitta, Larsson, Lars-Olof, Sandmark, Jenny, Castaldo, Marie, Dekker, Niek, Karlsson, Ulla, Hurt-Camejo, Eva
Published in ACS medicinal chemistry letters (13.10.2016)
Published in ACS medicinal chemistry letters (13.10.2016)
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Journal Article
Lead Optimization of Ethyl 6‑Aminonicotinate Acyl Sulfonamides as Antagonists of the P2Y12 Receptor. Separation of the Antithrombotic Effect and Bleeding for Candidate Drug AZD1283
Bach, Peter, Antonsson, Thomas, Bylund, Ruth, Björkman, Jan-Arne, Österlund, Krister, Giordanetto, Fabrizio, van Giezen, J. J. J, Andersen, Søren M, Zachrisson, Helen, Zetterberg, Fredrik
Published in Journal of medicinal chemistry (12.09.2013)
Published in Journal of medicinal chemistry (12.09.2013)
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Journal Article
Early Drug Development: From A Drug Candidate to the Clinic
Giordanetto, Fabrizio, Mannhold, Raimund, Buschmann, Helmut, Holenz, J rg
Year of Publication 11.06.2018
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Year of Publication 11.06.2018
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Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
Doak, Bradley Croy, Over, Bjӧrn, Giordanetto, Fabrizio, Kihlberg, Jan
Published in Chemistry & biology (18.09.2014)
Published in Chemistry & biology (18.09.2014)
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Journal Article
Discovery of 4-hydroxy-1,6-naphthyridine-3-carbonitrile derivatives as novel PDE10A inhibitors
Bauer, Udo, Giordanetto, Fabrizio, Bauer, Martin, O’Mahony, Gavin, Johansson, Kjell E., Knecht, Wolfgang, Hartleib-Geschwindner, Judith, Carlsson, Eva Töppner, Enroth, Cristofer
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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Journal Article
Disruption of the PP1/GADD34 complex induces calreticulin exposure
Kepp, Oliver, Galluzzi, Lorenzo, Giordanetto, Fabrizio, Tesniere, Antoine, Vitale, Ilio, Martins, Isabelle, Schlemmer, Frèdèric, Adjemian, Sandy, Zitvogel, Laurence, Kroemer, Guido
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
Published in Cell cycle (Georgetown, Tex.) (01.12.2009)
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