In-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach
Mecozzi, Laura, Mambrini, Martina, Ruscitti, Francesca, Ferrini, Erica, Ciccimarra, Roberta, Ravanetti, Francesca, Sverzellati, Nicola, Silva, Mario, Ruffini, Livia, Belenkov, Sasha, Civelli, Maurizio, Villetti, Gino, Stellari, Fabio Franco
Published in Scientific reports (30.10.2020)
Published in Scientific reports (30.10.2020)
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SSC-ILD mouse model induced by osmotic minipump delivered bleomycin: effect of Nintedanib
Ravanetti, Francesca, Ferrini, Erica, Ragionieri, Luisa, Khalajzeyqami, Zahra, Nicastro, Maria, Ridwan, Yanto, Kleinjan, Alex, Villetti, Gino, Grandi, Andrea, Stellari, Franco Fabio
Published in Scientific reports (16.09.2021)
Published in Scientific reports (16.09.2021)
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Pivotal role of micro-CT technology in setting up an optimized lung fibrosis mouse model for drug screening
Khalajzeyqami, Zahra, Grandi, Andrea, Ferrini, Erica, Ravanetti, Francesca, Leo, Ludovica, Mambrini, Martina, Giardino, Luciana, Villetti, Gino, Stellari, Franco Fabio
Published in PloS one (15.06.2022)
Published in PloS one (15.06.2022)
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Harnessing the translational power of bleomycin model: new insights to guide drug discovery for idiopathic pulmonary fibrosis
Murgo, Annalisa, Bignami, Fabio, Federico, Giuseppina, Villetti, Gino, Civelli, Maurizio, Sala, Angelo, Miglietta, Daniela
Published in Frontiers in pharmacology (30.11.2023)
Published in Frontiers in pharmacology (30.11.2023)
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Micro-CT-assisted identification of the optimal time-window for antifibrotic treatment in a bleomycin mouse model of long-lasting pulmonary fibrosis
Buccardi, Martina, Grandi, Andrea, Ferrini, Erica, Buseghin, Davide, Villetti, Gino, Civelli, Maurizio, Sverzellati, Nicola, Aliverti, Andrea, Pennati, Francesca, Stellari, Franco Fabio
Published in Scientific reports (26.06.2024)
Published in Scientific reports (26.06.2024)
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A fully automated micro‑CT deep learning approach for precision preclinical investigation of lung fibrosis progression and response to therapy
Buccardi, Martina, Ferrini, Erica, Pennati, Francesca, Vincenzi, Elena, Ledda, Roberta Eufrasia, Grandi, Andrea, Buseghin, Davide, Villetti, Gino, Sverzellati, Nicola, Aliverti, Andrea, Stellari, Franco Fabio
Published in Respiratory research (09.05.2023)
Published in Respiratory research (09.05.2023)
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Proteomic Fingerprint of Lung Fibrosis Progression and Response to Therapy in Bleomycin-Induced Mouse Model
Principi, Lucrezia, Ferrini, Erica, Ciccimarra, Roberta, Pagani, Lisa, Chinello, Clizia, Previtali, Paolo, Smith, Andrew, Villetti, Gino, Zoboli, Matteo, Ravanetti, Francesca, Stellari, Franco Fabio, Magni, Fulvio, Piga, Isabella
Published in International journal of molecular sciences (23.02.2023)
Published in International journal of molecular sciences (23.02.2023)
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Quantification of Lung Fibrosis in IPF-Like Mouse Model and Pharmacological Response to Treatment by Micro-Computed Tomography
Ruscitti, Francesca, Ravanetti, Francesca, Bertani, Valeria, Ragionieri, Luisa, Mecozzi, Laura, Sverzellati, Nicola, Silva, Mario, Ruffini, Livia, Menozzi, Valentina, Civelli, Maurizio, Villetti, Gino, Stellari, Franco Fabio
Published in Frontiers in pharmacology (21.07.2020)
Published in Frontiers in pharmacology (21.07.2020)
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CHF6297: a novel potent and selective p38 MAPK inhibitor with robust anti-inflammatory activity and suitable for inhaled pulmonary administration as dry powder
Martucci, Cataldo, Allen, Andrew Dennis, Moretto, Nadia, Bagnacani, Valentina, Fioni, Alessandro, Patacchini, Riccardo, Civelli, Maurizio, Villetti, Gino, Facchinetti, Fabrizio
Published in Frontiers in pharmacology (14.03.2024)
Published in Frontiers in pharmacology (14.03.2024)
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Pharmacological characterization of a highly selective Rho kinase (ROCK) inhibitor and its therapeutic effects in experimental pulmonary hypertension
Cantoni, Silvia, Cavalli, Stefano, Pastore, Fiorella, Accetta, Alessandro, Pala, Daniele, Vaccaro, Fabio, Cesari, Nicola, De Logu, Francesco, Nassini, Romina, Villetti, Gino, Facchinetti, Fabrizio
Published in European journal of pharmacology (05.05.2019)
Published in European journal of pharmacology (05.05.2019)
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The PDE4 Inhibitor Tanimilast Blunts Proinflammatory Dendritic Cell Activation by SARS-CoV-2 ssRNAs
Nguyen, Hoang Oanh, Schioppa, Tiziana, Tiberio, Laura, Facchinetti, Fabrizio, Villetti, Gino, Civelli, Maurizio, Del Prete, Annalisa, Sozio, Francesca, Gaudenzi, Carolina, Passari, Mauro, Barbazza, Ilaria, Sozzani, Silvano, Salvi, Valentina, Bosisio, Daniela
Published in Frontiers in immunology (24.01.2022)
Published in Frontiers in immunology (24.01.2022)
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The PDE4 Inhibitor Tanimilast Restrains the Tissue-Damaging Properties of Human Neutrophils
Schioppa, Tiziana, Nguyen, Hoang Oanh, Salvi, Valentina, Maugeri, Norma, Facchinetti, Fabrizio, Villetti, Gino, Civelli, Maurizio, Gaudenzi, Carolina, Passari, Mauro, Sozio, Francesca, Barbazza, Ilaria, Tamassia, Nicola, Cassatella, Marco A, Del Prete, Annalisa, Bosisio, Daniela, Tiberio, Laura
Published in International journal of molecular sciences (29.04.2022)
Published in International journal of molecular sciences (29.04.2022)
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The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation
Nguyen, Hoang Oanh, Salvi, Valentina, Tiberio, Laura, Facchinetti, Fabrizio, Govoni, Mirco, Villetti, Gino, Civelli, Maurizio, Barbazza, Ilaria, Gaudenzi, Carolina, Passari, Mauro, Schioppa, Tiziana, Sozio, Francesca, Del Prete, Annalisa, Sozzani, Silvano, Bosisio, Daniela
Published in Journal of translational medicine (10.05.2022)
Published in Journal of translational medicine (10.05.2022)
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Modulation of Human Dendritic Cell Functions by Phosphodiesterase-4 Inhibitors: Potential Relevance for the Treatment of Respiratory Diseases
Nguyen, Hoang Oanh, Tiberio, Laura, Facchinetti, Fabrizio, Ripari, Giulia, Violi, Valentina, Villetti, Gino, Salvi, Valentina, Bosisio, Daniela
Published in Pharmaceutics (31.08.2023)
Published in Pharmaceutics (31.08.2023)
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Physiological, Biochemical, and Biophysical Characterization of the Lung-Lavaged Spontaneously-Breathing Rabbit as a Model for Respiratory Distress Syndrome
Ricci, Francesca, Catozzi, Chiara, Murgia, Xabier, Rosa, Brenda, Amidani, Davide, Lorenzini, Luca, Bianco, Federico, Rivetti, Claudio, Catinella, Silvia, Villetti, Gino, Civelli, Maurizio, Pioselli, Barbara, Dani, Carlo, Salomone, Fabrizio
Published in PloS one (06.01.2017)
Published in PloS one (06.01.2017)
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Time-resolved transcriptomic profiling of the developing rabbit's lungs: impact of premature birth and implications for modelling bronchopulmonary dysplasia
Storti, Matteo, Faietti, Maria Laura, Murgia, Xabier, Catozzi, Chiara, Minato, Ilaria, Tatoni, Danilo, Cantarella, Simona, Ravanetti, Francesca, Ragionieri, Luisa, Ciccimarra, Roberta, Zoboli, Matteo, Vilanova, Mar, Sánchez-Jiménez, Ester, Gay, Marina, Vilaseca, Marta, Villetti, Gino, Pioselli, Barbara, Salomone, Fabrizio, Ottonello, Simone, Montanini, Barbara, Ricci, Francesca
Published in Respiratory research (15.03.2023)
Published in Respiratory research (15.03.2023)
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Surfactant replacement therapy in combination with different non-invasive ventilation techniques in spontaneously-breathing, surfactant-depleted adult rabbits
Ricci, Francesca, Casiraghi, Costanza, Storti, Matteo, D'Alò, Francesco, Catozzi, Chiara, Ciccimarra, Roberta, Ravanetti, Francesca, Cacchioli, Antonio, Villetti, Gino, Civelli, Maurizio, Murgia, Xabi, Carnielli, Virgilio, Salomone, Fabrizio
Published in PloS one (12.07.2018)
Published in PloS one (12.07.2018)
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Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair
Wu, Xinhui, Verschut, Vicky, Woest, Manon E, Ng-Blichfeldt, John-Poul, Matias, Ana, Villetti, Gino, Accetta, Alessandro, Facchinetti, Fabrizio, Gosens, Reinoud, Kistemaker, Loes E M
Published in Frontiers in pharmacology (20.01.2021)
Published in Frontiers in pharmacology (20.01.2021)
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Longitudinal assessment of bleomycin-induced lung fibrosis by Micro-CT correlates with histological evaluation in mice
Ruscitti, Francesca, Ravanetti, Francesca, Essers, Jeroen, Ridwan, Yanto, Belenkov, Sasha, Vos, Wim, Ferreira, Francisca, KleinJan, Alex, van Heijningen, Paula, Van Holsbeke, Cedric, Cacchioli, Antonio, Villetti, Gino, Stellari, Franco Fabio
Published in Multidisciplinary respiratory medicine (10.04.2017)
Published in Multidisciplinary respiratory medicine (10.04.2017)
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Multiphase micro-computed tomography reconstructions provide dynamic respiratory function in a mouse lung fibrosis model
Pennati, Francesca, Belenkov, Sasha, Buccardi, Martina, Ferrini, Erica, Sverzellati, Nicola, Villetti, Gino, Aliverti, Andrea, Stellari, Franco Fabio
Published in iScience (15.03.2024)
Published in iScience (15.03.2024)
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