A biomimetic multicellular model of the airways using primary human cells
Sellgren, Katelyn L, Butala, Elizabeth J, Gilmour, Brian P, Randell, Scott H, Grego, Sonia
Published in Lab on a chip (01.01.2014)
Published in Lab on a chip (01.01.2014)
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Journal Article
Diarylureas as Allosteric Modulators of the Cannabinoid CB1 Receptor: Structure–Activity Relationship Studies on 1‑(4-Chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1)
German, Nadezhda, Decker, Ann M, Gilmour, Brian P, Gay, Elaine A, Wiley, Jenny L, Thomas, Brian F, Zhang, Yanan
Published in Journal of medicinal chemistry (25.09.2014)
Published in Journal of medicinal chemistry (25.09.2014)
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The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor
Perrey, David A., Decker, Ann M., Li, Jun-Xu, Gilmour, Brian P., Thomas, Brian F., Harris, Danni L., Runyon, Scott P., Zhang, Yanan
Published in Bioorganic & medicinal chemistry (01.09.2015)
Published in Bioorganic & medicinal chemistry (01.09.2015)
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Journal Article
Synthesis, Pharmacological Characterization, and Structure–Activity Relationship Studies of Small Molecular Agonists for the Orphan GPR88 Receptor
Jin, Chunyang, Decker, Ann M, Huang, Xi-Ping, Gilmour, Brian P, Blough, Bruce E, Roth, Bryan L, Hu, Yang, Gill, Joseph B, Zhang, X. Peter
Published in ACS chemical neuroscience (16.07.2014)
Published in ACS chemical neuroscience (16.07.2014)
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Journal Article
Effect of 1‑Substitution on Tetrahydroisoquinolines as Selective Antagonists for the Orexin‑1 Receptor
Perrey, David A, German, Nadezhda A, Decker, Ann M, Thorn, David, Li, Jun-Xu, Gilmour, Brian P, Thomas, Brian F, Harris, Danni L, Runyon, Scott P, Zhang, Yanan
Published in ACS chemical neuroscience (15.04.2015)
Published in ACS chemical neuroscience (15.04.2015)
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Journal Article
Validation of a High-Throughput Calcium Mobilization Assay for the Human Trace Amine-Associated Receptor 1
Decker, Ann M., Mathews, Kelly M., Blough, Bruce E., Gilmour, Brian P.
Published in SLAS discovery (01.01.2021)
Published in SLAS discovery (01.01.2021)
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Journal Article
Identification of 1‑({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)‑1H‑pyrazol-3-yl]carbonyl}amino)cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin Receptor Type 2 Compound
Thomas, James B, Giddings, Angela M, Wiethe, Robert W, Olepu, Srinivas, Warner, Keith R, Sarret, Philippe, Gendron, Louis, Longpre, Jean-Michel, Zhang, Yanan, Runyon, Scott P, Gilmour, Brian P
Published in Journal of medicinal chemistry (26.06.2014)
Published in Journal of medicinal chemistry (26.06.2014)
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Identification of N‑[(5-{[(4-Methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)‑1H‑indol-1-yl)acetyl]‑l‑leucine (NTRC-824), a Neurotensin-like Nonpeptide Compound Selective for the Neurotensin Receptor Type 2
Thomas, James B, Giddings, Angela M, Wiethe, Robert W, Olepu, Srinivas, Warner, Keith R, Sarret, Philippe, Gendron, Louis, Longpre, Jean-Michel, Zhang, Yanan, Runyon, Scott P, Gilmour, Brian P
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
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Journal Article
Truncated Orexin Peptides: Structure–Activity Relationship Studies
German, Nadezhda A, Decker, Ann M, Gilmour, Brian P, Thomas, Brian F, Zhang, Yanan
Published in ACS medicinal chemistry letters (12.12.2013)
Published in ACS medicinal chemistry letters (12.12.2013)
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Journal Article
Diaryl urea analogues of SB-334867 as orexin-1 receptor antagonists
Perrey, David A., Gilmour, Brian P., Runyon, Scott P., Thomas, Brian F., Zhang, Yanan
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Journal Article
Discovery of N‑{4-[(3-Hydroxyphenyl)-3-methylpiperazin-1-yl]methyl-2-methylpropyl}-4-phenoxybenzamide Analogues as Selective Kappa Opioid Receptor Antagonists
Kormos, Chad M, Jin, Chunyang, Cueva, Juan Pablo, Runyon, Scott P, Thomas, James B, Brieaddy, Lawrence E, Mascarella, S. Wayne, Navarro, Hernán A, Gilmour, Brian P, Carroll, F. Ivy
Published in Journal of medicinal chemistry (13.06.2013)
Published in Journal of medicinal chemistry (13.06.2013)
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Journal Article
Structure-activity relationship studies on the tetrahydroisoquinoline-based orexin 1 receptor antagonists: The 1-benzyl position
Zhang, Yanan, Perrey, David A, Harris, Danni L, German, Nadezhda A, Decker, Ann M, Gilmour, Brian P, Thomas, Brian F
Published in Drug and alcohol dependence (01.01.2015)
Published in Drug and alcohol dependence (01.01.2015)
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Journal Article
Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-L-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2
Thomas, James B., Giddings, Angela M., Olepu, Srinivas, Wiethe, Robert W., Harris, Danni L., Narayanan, Sanju, Warner, Keith R., Sarret, Philippe, Longpre, Jean-Michel, Runyon, Scott P., Gilmour, Brian P.
Published in Bioorganic & medicinal chemistry letters (15.01.2015)
Published in Bioorganic & medicinal chemistry letters (15.01.2015)
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Journal Article
The effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the Orexin-1 receptor
Zhang, Yanan, Perrey, David A, German, Nadezhda A, Decker, Ann M, Thorn, David, Li, Jun-Xu, Gilmour, Brian P, Thomas, B.F, Harris, Danni L, Runyon, Scott P
Published in Drug and alcohol dependence (01.11.2015)
Published in Drug and alcohol dependence (01.11.2015)
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Journal Article
Effect of the 3- and 4‑Methyl Groups on the Opioid Receptor Properties of N‑Substituted trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines
Kormos, Chad M, Cueva, Juan Pablo, Gichinga, Moses G, Runyon, Scott P, Thomas, James B, Brieaddy, Lawrence E, Mascarella, S. Wayne, Gilmour, Brian P, Navarro, Hernán A, Carroll, F. Ivy
Published in Journal of medicinal chemistry (10.04.2014)
Published in Journal of medicinal chemistry (10.04.2014)
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Journal Article
The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2
Thomas, James B., Giddings, Angela M., Olepu, Srinivas, Wiethe, Robert W., Warner, Keith R., Sarret, Philippe, Longpre, Jean-Michel, Runyon, Scott P., Gilmour, Brian P.
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
Published in Bioorganic & medicinal chemistry letters (15.05.2015)
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