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Rational design of potent GSK3β inhibitors with selectivity for Cdk1 and Cdk2

Rational design of potent GSK3β inhibitors with selectivity for Cdk1 and Cdk2

by Lesuisse, Dominique, Dutruc-Rosset, Gilles, Tiraboschi, Gilles, Dreyer, Matthias K., Maignan, Sébastien, Chevalier, Alain, Halley, Frank, Bertrand, Philippe, Burgevin, Marie-Claude, Quarteronet, Dominique, Rooney, Thomas
Published in Bioorganic & medicinal chemistry letters (15.03.2010)

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Journal Article

Rational design of potent GSK3b inhibitors with selectivity for Cdk1 and Cdk2

Rational design of potent GSK3b inhibitors with selectivity for Cdk1 and Cdk2

by Lesuisse, Dominique, Dutruc-Rosset, Gilles, Tiraboschi, Gilles, Dreyer, Matthias K, Maignan, Sebastien, Chevalier, Alain, Halley, Frank, Bertrand, Philippe, Burgevin, Marie-Claude, Quarteronet, Dominique, Rooney, Thomas
Published in Bioorganic & medicinal chemistry letters (15.03.2010)

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Journal Article

Design of potent and selective GSK3β inhibitors with acceptable safety profile and pharmacokinetics

by Lesuisse, Dominique, Tiraboschi, Gilles, Krick, Alain, Abecassis, Pierre-Yves, Dutruc-Rosset, Gilles, Babin, Didier, Halley, Frank, Châtreau, Fabienne, Lachaud, Sylvette, Chevalier, Alain, Quarteronet, Dominique, Burgevin, Marie-Claude, Amara, Céline, Bertrand, Philippe, Rooney, Thomas
Published in Bioorganic & medicinal chemistry letters (01.04.2010)

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Journal Article

Design of potent and selective GSK3b inhibitors with acceptable safety profile and pharmacokinetics

by Lesuisse, Dominique, Tiraboschi, Gilles, Krick, Alain, Abecassis, Pierre-Yves, Dutruc-Rosset, Gilles, Babin, Didier, Halley, Frank, Chatreau, Fabienne, Lachaud, Sylvette, Chevalier, Alain, Quarteronet, Dominique, Burgevin, Marie-Claude, Amara, Celine, Bertrand, Philippe, Rooney, Thomas
Published in Bioorganic & medicinal chemistry letters (01.04.2010)

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Journal Article

COMPUESTOS DERIVADOS DE ESTREPTOGRAMINAS DEL GRUPO B; COMPUESTO INTERMEDIARIO; COMPOSICION FARMACEUTICA; PROCEDIMIENTO DE PREPARACION; UTILES COMO AGENTES ANTIMICROBIANOS

COMPUESTOS DERIVADOS DE ESTREPTOGRAMINAS DEL GRUPO B; COMPUESTO INTERMEDIARIO; COMPOSICION FARMACEUTICA; PROCEDIMIENTO DE PREPARACION; UTILES COMO AGENTES ANTIMICROBIANOS

by BACQUE ERIC; HARRIERE JEAN-CLAUDE; DOERFLINGER GILLES; DUTRUC-ROSSET GILLES; PANTEL GUY
Year of Publication 03.06.2005

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Patent

Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2

Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2

by Lesuisse, Dominique, Dutruc-Rosset, Gilles, Tiraboschi, Gilles, Dreyer, Matthias K, Maignan, Sébastien, Chevalier, Alain, Halley, Frank, Bertrand, Philippe, Burgevin, Marie-Claude, Quarteronet, Dominique, Rooney, Thomas
Published in Bioorganic & medicinal chemistry letters (15.03.2010)

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Journal Article

Design of potent and selective GSK3beta inhibitors with acceptable safety profile and pharmacokinetics

by Lesuisse, Dominique, Tiraboschi, Gilles, Krick, Alain, Abecassis, Pierre-Yves, Dutruc-Rosset, Gilles, Babin, Didier, Halley, Frank, Châtreau, Fabienne, Lachaud, Sylvette, Chevalier, Alain, Quarteronet, Dominique, Burgevin, Marie-Claude, Amara, Céline, Bertrand, Philippe, Rooney, Thomas
Published in Bioorganic & medicinal chemistry letters (01.04.2010)

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Journal Article

Chirality directed self-assembly. Resolution of 2,5-diazabicyclo[2.2.2]octane-3,6-dione and crystal structures of its racemic and (−) enantiomeric forms

Chirality directed self-assembly. Resolution of 2,5-diazabicyclo[2.2.2]octane-3,6-dione and crystal structures of its racemic and (−) enantiomeric forms

by Brienne, Marie-Josèphe, Gabard, Jacqueline, Leclercq, Martine, Lehn, Jean-Marie, Cesario, Michèle, Pascard, Claudine, Chevé, Michel, Dutruc-Rosset, Gilles
Published in Tetrahedron letters (31.10.1994)

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Journal Article

Electrochemical removal of the picolinoyl group under mild acidic conditions. Application to the protection of amines in peptide synthesis

Electrochemical removal of the picolinoyl group under mild acidic conditions. Application to the protection of amines in peptide synthesis

by Auzeil, Nicolas, Dutruc-Rosset, Gilles, Largeron, Martine
Published in Tetrahedron letters (31.03.1997)

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Journal Article

AMINOINDAZOLE DERIVATIVES AS PROTEIN-KINASE INHIBITORS

AMINOINDAZOLE DERIVATIVES AS PROTEIN-KINASE INHIBITORS

by LESUISSE, DOMINIQUE, ROONEY, THOMAS, DUTRUC-ROSSET, GILLES, HALLEY, FRANCK
Year of Publication 26.02.2014

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Patent

AMINOINDAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF INTERMEDIATES OF SAID METHOD AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

AMINOINDAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF INTERMEDIATES OF SAID METHOD AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

by LESUISSE, DOMINIQUE, ROONEY, THOMAS, DUTRUC-ROSSET, GILLES, HALLEY, FRANCK
Year of Publication 31.05.2013

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Patent

AMINOINDAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF INTERMEDIATES OF SAID METHOD AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

AMINOINDAZOLE DERIVATIVES, PREPARATION METHOD THEREOF AND USE OF INTERMEDIATES OF SAID METHOD AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME

by LESUISSE, DOMINIQUE, ROONEY, THOMAS, DUTRUC-ROSSET, GILLES, HALLEY, FRANK
Year of Publication 28.02.2013

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Patent

DERIVADO DO GRUPO B DAS ESTREPTOGRAMINAS, PROCESSO DE PREPARAÇÃO DE UM DERIVADO DE ESTREPTOGRAMINA, DERIVADO DE ESTREPTOGRAMINA, COMPOSIÇÕES PARMACÊUTICAS, E, ASSOCIAÇÕES DE UM DERIVADO DE ESTREPTOGRAMINA DO GRUPO B

DERIVADO DO GRUPO B DAS ESTREPTOGRAMINAS, PROCESSO DE PREPARAÇÃO DE UM DERIVADO DE ESTREPTOGRAMINA, DERIVADO DE ESTREPTOGRAMINA, COMPOSIÇÕES PARMACÊUTICAS, E, ASSOCIAÇÕES DE UM DERIVADO DE ESTREPTOGRAMINA DO GRUPO B

by GILLES DOERFLINGER, JEAN-CLAUDE BARRIERE, GILLES DUTRUC-ROSSET, ERIC BACQUE, GUY PANTEL
Year of Publication 10.03.2015

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Patent

1,1-diphenyl-3-dialkylamino-1-silacyclopentane derivatives: A new class of potent and selective 5-HT 2A antagonists

1,1-diphenyl-3-dialkylamino-1-silacyclopentane derivatives: A new class of potent and selective 5-HT 2A antagonists

by Damour, Dominique, Barreau, Michel, Dutruc-Rosset, Gilles, Doble, Adam, Piot, Odile, Mignani, Serge
Published in Bioorganic & medicinal chemistry letters (1994)

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Journal Article

1,1-diphenyl-3-dialkylamino-1-silacyclopentane derivatives: A new class of potent and selective 5-HT2A antagonists

1,1-diphenyl-3-dialkylamino-1-silacyclopentane derivatives: A new class of potent and selective 5-HT2A antagonists

by Damour, Dominique, Barreau, Michel, Dutruc-Rosset, Gilles, Doble, Adam, Piot, Odile, Mignani, Serge
Published in Bioorganic & medicinal chemistry letters (10.02.1994)

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Journal Article

DERIVES D'AMINOINDAZOLES COMME INHIBITEURS DE PROTEINE-KINASE

DERIVES D'AMINOINDAZOLES COMME INHIBITEURS DE PROTEINE-KINASE

by DUTRUC-ROSSET, Gilles, LESUISSE, Dominique, HALLEY, Franck, ROONEY, Thomas
Year of Publication 10.10.2010

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Patent

INTERMEDIATE COMPOUND FOR SYNTHESIZING AMINOINDAZOLE DERIVATIVE

INTERMEDIATE COMPOUND FOR SYNTHESIZING AMINOINDAZOLE DERIVATIVE

by ROONEY THOMAS, DUTRUC-ROSSET GILLES, HALLEY FRANCK, LESUISSE DOMINIQUE
Year of Publication 07.10.2010

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Patent

DERIVES D'AMINOINDAZOLES, PROCEDE DE PREPARATION ET INTERMEDIAIRES DE CE PROCEDE A TITRE DE MEDICAMENTS ET COMPOSITIONS PHARMACEUTIQUES LES RENFERMANT

DERIVES D'AMINOINDAZOLES, PROCEDE DE PREPARATION ET INTERMEDIAIRES DE CE PROCEDE A TITRE DE MEDICAMENTS ET COMPOSITIONS PHARMACEUTIQUES LES RENFERMANT

by ROONEY THOMAS, DUTRUC ROSSET GILLES, LESUISSE DOMINIQUE
Year of Publication 11.01.2008

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Patent

DERIVES D'AMINOINDAZOLES COMME INHIBITEURS DE PROTEINE-KINASE

DERIVES D'AMINOINDAZOLES COMME INHIBITEURS DE PROTEINE-KINASE

by LESUISSE, DOMINIQUE, ROONEY, THOMAS, DUTRUC-ROSSET, GILLES, HALLEY, FRANCK
Year of Publication 10.06.2010

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Patent

Aminoindazole derivatives, preparation method thereof and use of intermediates of said method as medicaments and pharmaceutical compositions containing same

Aminoindazole derivatives, preparation method thereof and use of intermediates of said method as medicaments and pharmaceutical compositions containing same

by FRANCK HALLEY, THOMAS ROONEY, GILLES DUTRUC-ROSSET, DOMINIQUE LESUISSE
Year of Publication 15.04.2010

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Patent

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