Engineered CAR-Macrophages as Adoptive Immunotherapies for Solid Tumors
Sloas, Christopher, Gill, Saar, Klichinsky, Michael
Published in Frontiers in immunology (24.11.2021)
Published in Frontiers in immunology (24.11.2021)
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Decade-long leukaemia remissions with persistence of CD4+ CAR T cells
Melenhorst, J. Joseph, Chen, Gregory M., Wang, Meng, Porter, David L., Chen, Changya, Collins, McKensie A., Gao, Peng, Bandyopadhyay, Shovik, Sun, Hongxing, Zhao, Ziran, Lundh, Stefan, Pruteanu-Malinici, Iulian, Nobles, Christopher L., Maji, Sayantan, Frey, Noelle V., Gill, Saar I., Loren, Alison W., Tian, Lifeng, Kulikovskaya, Irina, Gupta, Minnal, Ambrose, David E., Davis, Megan M., Fraietta, Joseph A., Brogdon, Jennifer L., Young, Regina M., Chew, Anne, Levine, Bruce L., Siegel, Donald L., Alanio, Cécile, Wherry, E. John, Bushman, Frederic D., Lacey, Simon F., Tan, Kai, June, Carl H.
Published in Nature (London) (17.02.2022)
Published in Nature (London) (17.02.2022)
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Human chimeric antigen receptor macrophages for cancer immunotherapy
Klichinsky, Michael, Ruella, Marco, Shestova, Olga, Lu, Xueqing Maggie, Best, Andrew, Zeeman, Martha, Schmierer, Maggie, Gabrusiewicz, Konrad, Anderson, Nicholas R., Petty, Nicholas E., Cummins, Katherine D., Shen, Feng, Shan, Xinhe, Veliz, Kimberly, Blouch, Kristin, Yashiro-Ohtani, Yumi, Kenderian, Saad S., Kim, Miriam Y., O’Connor, Roddy S., Wallace, Stephen R., Kozlowski, Miroslaw S., Marchione, Dylan M., Shestov, Maksim, Garcia, Benjamin A., June, Carl H., Gill, Saar
Published in Nature biotechnology (01.08.2020)
Published in Nature biotechnology (01.08.2020)
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Rapid manufacturing of non-activated potent CAR T cells
Ghassemi, Saba, Durgin, Joseph S., Nunez-Cruz, Selene, Patel, Jai, Leferovich, John, Pinzone, Marilia, Shen, Feng, Cummins, Katherine D., Plesa, Gabriela, Cantu, Vito Adrian, Reddy, Shantan, Bushman, Frederic D., Gill, Saar I., O’Doherty, Una, O’Connor, Roddy S., Milone, Michael C.
Published in Nature biomedical engineering (01.02.2022)
Published in Nature biomedical engineering (01.02.2022)
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Enhancing cellular immunotherapies in cancer by engineering selective therapeutic resistance
Wellhausen, Nils, Baek, Joanne, Gill, Saar I., June, Carl H.
Published in Nature reviews. Cancer (01.09.2024)
Published in Nature reviews. Cancer (01.09.2024)
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Better living through chemistry: CRISPR/Cas engineered T cells for cancer immunotherapy
Wellhausen, Nils, Agarwal, Sangya, Rommel, Philipp C, Gill, Saar I, June, Carl H
Published in Current opinion in immunology (01.02.2022)
Published in Current opinion in immunology (01.02.2022)
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Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell
Ruella, Marco, Xu, Jun, Barrett, David M., Fraietta, Joseph A., Reich, Tyler J., Ambrose, David E., Klichinsky, Michael, Shestova, Olga, Patel, Prachi R., Kulikovskaya, Irina, Nazimuddin, Farzana, Bhoj, Vijay G., Orlando, Elena J., Fry, Terry J., Bitter, Hans, Maude, Shannon L., Levine, Bruce L., Nobles, Christopher L., Bushman, Frederic D., Young, Regina M., Scholler, John, Gill, Saar I., June, Carl H., Grupp, Stephan A., Lacey, Simon F., Melenhorst, J. Joseph
Published in Nature medicine (01.10.2018)
Published in Nature medicine (01.10.2018)
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Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies
Ruella, Marco, Barrett, David M, Kenderian, Saad S, Shestova, Olga, Hofmann, Ted J, Perazzelli, Jessica, Klichinsky, Michael, Aikawa, Vania, Nazimuddin, Farzana, Kozlowski, Miroslaw, Scholler, John, Lacey, Simon F, Melenhorst, Jan J, Morrissette, Jennifer J D, Christian, David A, Hunter, Christopher A, Kalos, Michael, Porter, David L, June, Carl H, Grupp, Stephan A, Gill, Saar
Published in The Journal of clinical investigation (03.10.2016)
Published in The Journal of clinical investigation (03.10.2016)
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Gut microbiome correlates of response and toxicity following anti-CD19 CAR T cell therapy
Smith, Melody, Dai, Anqi, Ghilardi, Guido, Amelsberg, Kimberly V., Devlin, Sean M., Pajarillo, Raymone, Slingerland, John B., Beghi, Silvia, Herrera, Pamela S., Giardina, Paul, Clurman, Annelie, Dwomoh, Emmanuel, Armijo, Gabriel, Gomes, Antonio L. C., Littmann, Eric R., Schluter, Jonas, Fontana, Emily, Taur, Ying, Park, Jae H., Palomba, Maria Lia, Halton, Elizabeth, Ruiz, Josel, Jain, Tania, Pennisi, Martina, Afuye, Aishat Olaide, Perales, Miguel-Angel, Freyer, Craig W., Garfall, Alfred, Gier, Shannon, Nasta, Sunita, Landsburg, Daniel, Gerson, James, Svoboda, Jakub, Cross, Justin, Chong, Elise A., Giralt, Sergio, Gill, Saar I., Riviere, Isabelle, Porter, David L., Schuster, Stephen J., Sadelain, Michel, Frey, Noelle, Brentjens, Renier J., June, Carl H., Pamer, Eric G., Peled, Jonathan U., Facciabene, Andrea, van den Brink, Marcel R. M., Ruella, Marco
Published in Nature medicine (01.04.2022)
Published in Nature medicine (01.04.2022)
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Journal Article
Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy
Wellhausen, Nils, O'Connell, Ryan P, Lesch, Stefanie, Engel, Nils W, Rennels, Austin K, Gonzales, Donna, Herbst, Friederike, Young, Regina M, Garcia, K Christopher, Weiner, David, June, Carl H, Gill, Saar I
Published in Science translational medicine (20.09.2023)
Published in Science translational medicine (20.09.2023)
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A cellular antidote to specifically deplete anti-CD19 chimeric antigen receptor–positive cells
Ruella, Marco, Barrett, David M., Shestova, Olga, Perazzelli, Jessica, Posey, Avery D., Hong, Seok Jae, Kozlowski, Miroslaw, Lacey, Simon F., Melenhorst, J. Joseph, June, Carl H., Gill, Saar I.
Published in Blood (13.02.2020)
Published in Blood (13.02.2020)
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Journal Article
Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells
Singh, Nathan, Frey, Noelle V., Engels, Boris, Barrett, David M., Shestova, Olga, Ravikumar, Pranali, Cummins, Katherine D., Lee, Yong Gu, Pajarillo, Raymone, Chun, Inkook, Shyu, Amy, Highfill, Steven L., Price, Andrew, Zhao, Linlin, Peng, Liaomin, Granda, Brian, Ramones, Melissa, Lu, Xueqing Maggie, Christian, David A., Perazzelli, Jessica, Lacey, Simon F., Roy, Nathan H., Burkhardt, Janis K., Colomb, Florent, Damra, Mohammad, Abdel-Mohsen, Mohamed, Liu, Ting, Liu, Dongfang, Standley, Daron M., Young, Regina M., Brogdon, Jennifer L., Grupp, Stephan A., June, Carl H., Maude, Shannon L., Gill, Saar, Ruella, Marco
Published in Nature medicine (01.05.2021)
Published in Nature medicine (01.05.2021)
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Venetoclax and hypomethylating agents (HMAs) induce high response rates in MDS, including patients after HMA therapy failure
Ball, Brian J., Famulare, Christopher A., Stein, Eytan M., Tallman, Martin S., Derkach, Andriy, Roshal, Mikhail, Gill, Saar I., Manning, Benjamin M., Koprivnikar, Jamie, McCloskey, James, Testi, Rebecca, Prebet, Thomas, Al Ali, Najla H., Padron, Eric, Sallman, David A., Komrokji, Rami S., Goldberg, Aaron D.
Published in Blood advances (14.07.2020)
Published in Blood advances (14.07.2020)
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