Atu027, a liposomal small interfering RNA formulation targeting protein kinase N3, inhibits cancer progression
Aleku, Manuela, Schulz, Petra, Keil, Oliver, Santel, Ansgar, Schaeper, Ute, Dieckhoff, Britta, Janke, Oliver, Endruschat, Jens, Durieux, Birgit, Röder, Nadine, Löffler, Kathrin, Lange, Christian, Fechtner, Melanie, Möpert, Kristin, Fisch, Gerald, Dames, Sibylle, Arnold, Wolfgang, Jochims, Karin, Giese, Klaus, Wiedenmann, Bertram, Scholz, Arne, Kaufmann, Jörg
Published in Cancer research (Chicago, Ill.) (01.12.2008)
Published in Cancer research (Chicago, Ill.) (01.12.2008)
Get full text
Journal Article
Atu027 Prevents Pulmonary Metastasis in Experimental and Spontaneous Mouse Metastasis Models
SANTEL, Ansgar, ALEKU, Manuela, EISERMANN, Mona, LÖFFLER, Kathrin, FECHTNER, Melanie, FISCH, Gerald, VANK, Christiane, SCHAEPER, Ute, GIESE, Klaus, KAUFMANN, Jörg, RÖDER, Nadine, MÖPERT, Kristin, DURIEUX, Birgit, JANKE, Oliver, KEIL, Oliver, ENDRUSCHAT, Jens, DAMES, Sibylle, LANGE, Christian
Published in Clinical cancer research (15.11.2010)
Published in Clinical cancer research (15.11.2010)
Get full text
Journal Article
Cationic LNP-formulated mRNA expressing Tie2-agonist in the lung endothelium prevents pulmonary vascular leakage
Radloff, Katrin, Gutbier, Birgitt, Dunne, Charlotte Maeve, Moradian, Hanieh, Schwestka, Marko, Gossen, Manfred, Ahrens, Katharina, Kneller, Laura, Wang, Yadong, Moga, Akanksha, Gkionis, Leonidas, Keil, Oliver, Fehring, Volker, Tondera, Daniel, Giese, Klaus, Santel, Ansgar, Kaufmann, Jörg, Witzenrath, Martin
Published in Molecular therapy. Nucleic acids (12.12.2023)
Published in Molecular therapy. Nucleic acids (12.12.2023)
Get full text
Journal Article
Knockdown of MTP18, a Novel Phosphatidylinositol 3-Kinase-dependent Protein, Affects Mitochondrial Morphology and Induces Apoptosis
Tondera, Daniel, Santel, Ansgar, Schwarzer, Rolf, Dames, Sybille, Giese, Klaus, Klippel, Anke, Kaufmann, Jörg
Published in The Journal of biological chemistry (23.07.2004)
Published in The Journal of biological chemistry (23.07.2004)
Get full text
Journal Article
HMG domain proteins: architectural elements in the assembly of nucleoprotein structures
Get full text
Book Review
Journal Article
Structural basis for DNA bending by the architectural transcription factor LEF-1
Love, John J, Li, Xiang, Case, David A, Giese, Klaus, Crosschedl, Rudolf, Wright, Peter E
Published in Nature (London) (31.08.1995)
Published in Nature (London) (31.08.1995)
Get full text
Journal Article
Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin
Murphy, J.E, Zhou, S, Giese, K, Williams, L.T, Escobedo, J.A, Dwarki, V.J
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (09.12.1997)
Get full text
Journal Article
First-in-human phase I study of the liposomal RNA interference therapeutic Atu027 in patients with advanced solid tumors
Schultheis, Beate, Strumberg, Dirk, Santel, Ansgar, Vank, Christiane, Gebhardt, Frank, Keil, Oliver, Lange, Christian, Giese, Klaus, Kaufmann, Jörg, Khan, Michael, Drevs, Joachim
Published in Journal of clinical oncology (20.12.2014)
Published in Journal of clinical oncology (20.12.2014)
Get full text
Journal Article
Phase I clinical development of Atu027, a siRNA formulation targeting PKN3 in patients with advanced solid tumors
Strumberg, Dirk, Schultheis, Beate, Traugott, Ulrich, Vank, Christiane, Santel, Ansgar, Keil, Oliver, Giese, Klaus, Kaufmann, Jörg, Drevs, Joachim
Published in International journal of clinical pharmacology and therapeutics (01.01.2012)
Published in International journal of clinical pharmacology and therapeutics (01.01.2012)
Get more information
Journal Article
Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells
Czauderna, Frank, Fechtner, Melanie, Dames, Sibylle, Aygün, Hüseyin, Klippel, Anke, Pronk, Gijsbertus J., Giese, Klaus, Kaufmann, Jörg
Published in Nucleic acids research (01.06.2003)
Published in Nucleic acids research (01.06.2003)
Get full text
Journal Article
Identification of a novel aspartic-like protease differentially expressed in human breast cancer cell lines11GenBank accession number: BankIt246393 AF117892
Xin, Hong, Stephans, James C., Duan, Xiaozhu, Harrowe, Greg, Kim, Esther, Grieshammer, Uta, Kingsley, Chris, Giese, Klaus
Published in Biochimica et biophysica acta. Molecular basis of disease (01.06.2000)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.06.2000)
Get full text
Journal Article
First-in-human phase I study of the liposomal RNAi therapeutic Atu027 in patients with advanced cancer
Schultheis, Beate, Strumberg, Dirk, Santel, Ansgar, Gebhardt, Frank, Khan, Michael, Keil, Oliver, Giese, Klaus, Kaufmann, Jörg
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
Get full text
Journal Article
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase
SCHWARZER, Rolf, TONDERA, Daniel, ARNOLD, Wolfgang, GIESE, Klaus, KLIPPEL, Anke, KAUFMANN, Jörg
Published in Oncogene (10.02.2005)
Published in Oncogene (10.02.2005)
Get full text
Journal Article
Inducible shRNA expression for application in a prostate cancer mouse model
Czauderna, Frank, Santel, Ansgar, Hinz, Michael, Fechtner, Melanie, Durieux, Birgit, Fisch, Gerald, Leenders, Frauke, Arnold, Wolfgang, Giese, Klaus, Klippel, Anke, Kaufmann, Jörg
Published in Nucleic acids research (01.11.2003)
Published in Nucleic acids research (01.11.2003)
Get full text
Journal Article