Modelling response time profiles in the absence of drug concentrations: definition and performance evaluation of the K-PD model
Jacqmin, P, Snoeck, E, van Schaick, E A, Gieschke, R, Pillai, P, Steimer, J-L, Girard, P
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2007)
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2007)
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Population pharmacokinetics of ibandronate in Caucasian and Japanese healthy males and postmenopausal females
Pillai, G, Gieschke, R, Goggin, T, Barrett, J, Worth, E, Steimer, J L
Published in International journal of clinical pharmacology and therapeutics (01.12.2006)
Published in International journal of clinical pharmacology and therapeutics (01.12.2006)
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Population pharmacokinetic analysis of the major metabolites of capecitabine
GIESCHKE, R, REIGNER, B, BLESCH, K. S, STEIMER, J.-L
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2002)
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2002)
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Pharmacokinetic and pharmacodynamic interactions of bretazenil and diazepam with alcohol
VAN STEVENINCK, A. L., GIESCHKE, R., SCHOEMAKER, R. C., RONCARI, G., TUK, B., PIETERS, M. S. M., BREIMER, D. D., COHEN, A. F.
Published in British journal of clinical pharmacology (01.06.1996)
Published in British journal of clinical pharmacology (01.06.1996)
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Pharmacodynamic interactions of diazepam and intravenous alcohol at pseudo steady state
van Steveninck, A L, Gieschke, R, Schoemaker, H C, Pieters, M S, Kroon, J M, Breimer, D D, Cohen, A F
Published in Psychopharmacology (01.03.1993)
Published in Psychopharmacology (01.03.1993)
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A semimechanistic and mechanistic population PK–PD model for biomarker response to ibandronate, a new bisphosphonate for the treatment of osteoporosis
Pillai, Goonaseelan, Gieschke, Ronald, Goggin, Timothy, Jacqmin, Philippe, Schimmer, Ralph C., Steimer, Jean‐Louis
Published in British journal of clinical pharmacology (01.12.2004)
Published in British journal of clinical pharmacology (01.12.2004)
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Population pharmacokinetics and concentration–effect relationships of capecitabine metabolites in colorectal cancer patients
Gieschke, Ronald, Burger, Hans‐Ulrich, Reigner, Bruno, Blesch, Karen S., Steimer, Jean‐Louis
Published in British journal of clinical pharmacology (01.03.2003)
Published in British journal of clinical pharmacology (01.03.2003)
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Relationships between exposure to saquinavir monotherapy and antiviral response in HIV-positive patients
GIESCHKE, R, FOTTELER, B, BUSS, N, STEIMER, J.-L
Published in Clinical pharmacokinetics (01.07.1999)
Published in Clinical pharmacokinetics (01.07.1999)
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Potentiation of the pressor effect of oral and intravenous tyramine during administration of the selective MAO-A inhibitor moclobemide in healthy volunteers
Wijnands, S, Chang, P C, Blauw, G J, van den Krogt, J, Gieschke, R, Schoerlin, M P, van Brummelen, P
Published in Journal of psychopharmacology (Oxford) (01.01.1989)
Published in Journal of psychopharmacology (Oxford) (01.01.1989)
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Clinical pharmacokinetic/pharmacodynamic and physiologically based pharmacokinetic modeling in new drug development: the capecitabine experience
Blesch, Karen S, Gieschke, Ronald, Tsukamoto, Yuko, Reigner, Bruno G, Burger, Hans U, Steimer, Jean-Louis
Published in Investigational new drugs (01.05.2003)
Published in Investigational new drugs (01.05.2003)
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Integrated pharmacokinetics and pharmacodynamics of the novel catechol-O-methyltransferase inhibitor tolcapone during first administration to humans
Dingemanse, J, Jorga, K M, Schmitt, M, Gieschke, R, Fotteler, B, Zürcher, G, Da Prada, M, van Brummelen, P
Published in Clinical pharmacology and therapeutics (01.05.1995)
Published in Clinical pharmacology and therapeutics (01.05.1995)
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421 A new bio-mathematical model to describe the dynamics of HBV-DNA and infected hepatocytes in HBEAG-negative/anti-HBE-positive chronic hepatitis B patients treated with peginterferon alfa-2A (40KD) (PEGASYS®), lamivudine, or PEGASYS® plus lamivudine combin
Colombatto, P., Bizzarri, R., Civitano, L., Oliveri, F., Bonino, F., Germanidis, G., Farci, P., Kitis, G., Hadziyannis, S., Choudhury, S., Gieschke, R., Zahm, F., Brunetto, M.
Published in Journal of hepatology (2004)
Published in Journal of hepatology (2004)
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