CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus
Andreata, Francesco, Moynihan, Kelly D, Fumagalli, Valeria, Di Lucia, Pietro, Pappas, Danielle C, Kawashima, Keigo, Ni, Irene, Bessette, Paul H, Perucchini, Chiara, Bono, Elisa, Giustini, Leonardo, Nguyen, Henry C, Chin, S Michael, Yeung, Yik Andy, Gibbs, Craig S, Djuretic, Ivana, Iannacone, Matteo
Published in Science translational medicine (10.01.2024)
Published in Science translational medicine (10.01.2024)
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Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy
Werle-Lapostolle, Bettina, Bowden, Scott, Locarnini, Stephen, Wursthorn, Karsten, Petersen, Jorg, Lau, George, Trepo, Christian, Marcellin, Patrick, Goodman, Zachary, Delaney, 4th, William E, Xiong, Shelly, Brosgart, Carol L, Chen, Shan-Shan, Gibbs, Craig S, Zoulim, Fabien
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2004)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2004)
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Cathepsin A Is the Major Hydrolase Catalyzing the Intracellular Hydrolysis of the Antiretroviral Nucleotide Phosphonoamidate Prodrugs GS-7340 and GS-9131
BIRKUS, Gabriel, WANG, Ruth, XIAOHONG LIU, KUTTY, Nilima, MACARTHUR, Holly, CIHLAR, Tomas, GIBBS, Craig, SWAMINATHAN, Swami, LEE, William, MCDERMOTT, Martin
Published in Antimicrobial Agents and Chemotherapy (01.02.2007)
Published in Antimicrobial Agents and Chemotherapy (01.02.2007)
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Journal Article
Selection of a hepatitis B virus strain resistant to adefovir in a liver transplantation patient
VILLENEUVE, Jean-Pierre, DURANTEL, David, ZOULIM, Fabien, DURANTEL, Sandra, WESTLAND, Christopher, XIONG, Shelly, BROSGART, Carol L, GIBBS, Craig S, PARVAZ, Parviz, WERLE, Bettina, TREPO, Christian
Published in Journal of hepatology (01.12.2003)
Published in Journal of hepatology (01.12.2003)
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Journal Article
The Hepatitis B Virus Polymerase Mutation rtV173L Is Selected during Lamivudine Therapy and Enhances Viral Replication In Vitro
Delaney, 4th, William E, Yang, Huiling, Westland, Christopher E, Das, Kalyan, Arnold, Eddy, Gibbs, Craig S, Miller, Michael D, Xiong, Shelly
Published in Journal of Virology (01.11.2003)
Published in Journal of Virology (01.11.2003)
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Structural basis for the interaction of Bordetella pertussis adenylyl cyclase toxin with calmodulin
Guo, Qing, Shen, Yuequan, Lee, Young-Sam, Gibbs, Craig S, Mrksich, Milan, Tang, Wei-Jen
Published in The EMBO journal (21.09.2005)
Published in The EMBO journal (21.09.2005)
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Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
Arnold, Eddy, Tuske, Steve, Sarafianos, Stefan G, Clark, Arthur D, Ding, Jianping, Naeger, Lisa K, White, Kirsten L, Miller, Michael D, Gibbs, Craig S, Boyer, Paul L, Clark, Patrick, Wang, Gang, Gaffney, Barbara L, Jones, Roger A, Jerina, Donald M, Hughes, Stephen H
Published in Nature structural & molecular biology (01.05.2004)
Published in Nature structural & molecular biology (01.05.2004)
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Selective Inhibition of Anthrax Edema Factor by Adefovir, a Drug for Chronic Hepatitis B Virus Infection
Shen, Yuequan, Zhukovskaya, Natalia L., Zimmer, Michael I., Soelaiman, Sandriyana, Bergson, Pamela, Wang, Chyung-Ru, Gibbs, Craig S., Tang, Wei-Jen, Collier, R. John
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2004)
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Resistance surveillance in chronic hepatitis B patients treated with adefovir dipivoxil for up to 60 weeks
Yang, Huiling, Westland, Christopher E., Delaney, William E., Heathcote, Elizabeth J., Ho, Victoria, Fry, John, Brosgart, Carol, Gibbs, Craig S., Miller, Michael D., Xiong, Shelly
Published in Hepatology (Baltimore, Md.) (01.08.2002)
Published in Hepatology (Baltimore, Md.) (01.08.2002)
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Week 48 resistance surveillance in two phase 3 clinical studies of adefovir dipivoxil for chronic hepatitis B
Westland, Christopher E., Yang, Huiling, Delaney, William E., Gibbs, Craig S., Miller, Michael D., Wulfsohn, Michael, Fry, John, Brosgart, Carol L., Xiong, Shelly
Published in Hepatology (Baltimore, Md.) (01.07.2003)
Published in Hepatology (Baltimore, Md.) (01.07.2003)
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Inhibitory Effect of Adefovir on Viral DNA Synthesis and Covalently Closed Circular DNA Formation in Duck Hepatitis B Virus-Infected Hepatocytes In Vivo and In Vitro
DELMAS, Julien, SCHORR, Olivier, JAMARD, Catherine, GIBBS, Craig, TREPO, Christian, HANTZ, Olivier, ZOULIM, Fabien
Published in Antimicrobial Agents and Chemotherapy (01.02.2002)
Published in Antimicrobial Agents and Chemotherapy (01.02.2002)
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Molecular Modeling and Biochemical Characterization Reveal the Mechanism of Hepatitis B Virus Polymerase Resistance to Lamivudine (3TC) and Emtricitabine (FTC)
Das, K, Xiong, X, Yang, H, Westland, C E, Gibbs, C S, Sarafianos, S G, Arnold, E
Published in Journal of Virology (01.05.2001)
Published in Journal of Virology (01.05.2001)
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Journal Article
Antiviral effect of adefovir in combination with a DNA vaccine in the duck hepatitis B virus infection model
Le Guerhier, Franck, Thermet, Alexandre, Guerret, Sylvianne, Chevallier, Michèle, Jamard, Catherine, Gibbs, Craig S., Trépo, Christian, Cova, Lucyna, Zoulim, Fabien
Published in Journal of hepatology (01.03.2003)
Published in Journal of hepatology (01.03.2003)
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Journal Article
Antiviral Efficacy and Pharmacokinetics of Oral Adefovir Dipivoxil in Chronically Woodchuck Hepatitis Virus-Infected Woodchucks
CULLEN, John M, LI, Daniel H, BROWN, Cynthia, EISENBERG, Eugene J, CUNDY, Kenneth C, WOLFE, Julie, TOOLE, J. A. Y, GIBBS, Craig
Published in Antimicrobial Agents and Chemotherapy (01.10.2001)
Published in Antimicrobial Agents and Chemotherapy (01.10.2001)
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