β‐1 tubulin R307H SNP alters microtubule dynamics and affects severity of a hereditary thrombocytopenia
Basciano, P. A., Matakas, J., Pecci, A., Civaschi, E., Cagioni, C., Bompiani, N., Burger, P., Christos, P., Snyder, J. P., Bussel, J., Balduini, C. L., Giannakakou, P., Noris, P.
Published in Journal of thrombosis and haemostasis (01.04.2015)
Published in Journal of thrombosis and haemostasis (01.04.2015)
Get full text
Journal Article
Synthesis of epothilones A and B in solid and solution phase
Nicolaou, K. C, Winssinger, N, Pastor, J, Ninkovic, S, Sarabia, F, He, Y, Vourloumis, D, Yang, Z, Li, T, Giannakakou, P, Hamel, E
Published in Nature (London) (15.05.1997)
Published in Nature (London) (15.05.1997)
Get full text
Journal Article
2563 Screening and baseline analysis of circulating tumor cell (CTC) counts and androgen receptor (AR) localization with clinical characteristics of men with metastatic castration-resistant prostate cancer (mCRPC) in TAXYNERGY
Tagawa, S.T, Galletti, G, Antonarakis, E.S, Tasaki, S, Gjyrezi, A, Worroll, D, Portella, L, Kirby, B.J, Stewart, J, Zaher, A, Saad, F, Vanhuyse, M, Suri, S, Lannin, T.B, Gruber, C, Pratt, E, North, S, Eisenberger, M.A, Nanus, D.M, Giannakakou, P
Published in European journal of cancer (1990) (01.09.2015)
Published in European journal of cancer (1990) (01.09.2015)
Get full text
Journal Article
Chemical Synthesis and Biological Evaluation of cis- and trans-12,13-Cyclopropyl and 12,13-Cyclobutyl Epothilones and Related Pyridine Side Chain Analogues
Nicolaou, K. C, Namoto, Kenji, Ritzén, Andreas, Ulven, Trond, Shoji, Mitsuru, Li, Jim, D'Amico, Gina, Liotta, Dennis, French, Christopher T, Wartmann, Markus, Altmann, Karl-Heinz, Giannakakou, Paraskevi
Published in Journal of the American Chemical Society (26.09.2001)
Published in Journal of the American Chemical Society (26.09.2001)
Get full text
Journal Article
Combinations of paclitaxel and vinblastine and their effects on tubulin polymerization and cellular cytotoxicity : Characterization of a synergistic schedule
GIANNAKAKOU, P, VILLALBA, L, LI, H, PORUCHYNSKY, M, FOJO, T
Published in International journal of cancer (05.01.1998)
Published in International journal of cancer (05.01.1998)
Get full text
Journal Article
Capture of circulating tumor cells from whole blood of prostate cancer patients using geometrically enhanced differential immunocapture (GEDI) and a prostate-specific antibody
Gleghorn, Jason P, Pratt, Erica D, Denning, Denise, Liu, He, Bander, Neil H, Tagawa, Scott T, Nanus, David M, Giannakakou, Paraskevi A, Kirby, Brian J
Published in Lab on a chip (01.01.2010)
Published in Lab on a chip (01.01.2010)
Get full text
Journal Article
Both Microtubule-Stabilizing and Microtubule-Destabilizing Drugs Inhibit Hypoxia-Inducible Factor-1α Accumulation and Activity by Disrupting Microtubule Function
Escuin, Daniel, Kline, Erik R., Giannakakou, Paraskevi
Published in Cancer research (Chicago, Ill.) (01.10.2005)
Published in Cancer research (Chicago, Ill.) (01.10.2005)
Get full text
Journal Article
Phase I study of apalutamide (ARN) plus abiraterone acetate (AA), docetaxel (D) in patients (pts) with metastatic castrate-resistant prostate cancer (mCRPC)
Molina, A.M., Christos, P.J., Whang, Y., Nordquist, L., Hackett, A.L., Beltran, H., Faltas, B., Nanus, D., Giannakakou, P., Tagawa, S.T.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
Get full text
Journal Article
2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF
Mabjeesh, Nicola J., Escuin, Daniel, LaVallee, Theresa M., Pribluda, Victor S., Swartz, Glenn M., Johnson, Michelle S., Willard, Margaret T., Zhong, Hua, Simons, Jonathan W., Giannakakou, Paraskevi
Published in Cancer cell (01.04.2003)
Published in Cancer cell (01.04.2003)
Get full text
Journal Article
Mitotic Kinesin Inhibitors Induce Mitotic Arrest and Cell Death in Taxol-resistant and -sensitive Cancer Cells
Marcus, Adam I., Peters, Ulf, Thomas, Shala L., Garrett, Sarah, Zelnak, Amelia, Kapoor, Tarun M., Giannakakou, Paraskevi
Published in The Journal of biological chemistry (25.03.2005)
Published in The Journal of biological chemistry (25.03.2005)
Get full text
Journal Article
A Common Pharmacophore for Epothilone and Taxanes: Molecular Basis for Drug Resistance Conferred by Tubulin Mutations in Human Cancer Cells
Giannakakou, P, Gussio, R, Nogales, E, Downing, K H, Zaharevitz, D, Bollbuck, B, Poy, G, Sackett, D, Nicolaou, K C, Fojo, T
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (14.03.2000)
Get full text
Journal Article
p53 is associated with cellular microtubules and is transported to the nucleus by dynein
Giannakakou, Paraskevi, Sackett, Dan L, Ward, Yvona, Webster, Kevin R, Blagosklonny, Mikhail V, Fojo, Tito
Published in Nature cell biology (01.10.2000)
Published in Nature cell biology (01.10.2000)
Get full text
Journal Article
The Microtubule Stabilizing Agent Laulimalide Does Not Bind in the Taxoid Site, Kills Cells Resistant to Paclitaxel and Epothilones, and May Not Require Its Epoxide Moiety for Activity
Pryor, Donald E, O'Brate, Aurora, Bilcer, Geoffrey, Díaz, J. Fernando, Wang, Yuefang, Wang, Yong, Kabaki, Mikio, Jung, M. Katherine, Andreu, José M, Ghosh, Arun K, Giannakakou, Paraskevi, Hamel, Ernest
Published in Biochemistry (Easton) (23.07.2002)
Published in Biochemistry (Easton) (23.07.2002)
Get full text
Journal Article
[beta]-1 tubulin R307H SNP alters microtubule dynamics and affects severity of a hereditary thrombocytopenia
Basciano, P A, Matakas, J, Pecci, A, Civaschi, E, Cagioni, C, Bompiani, N, Burger, P, Christos, P, Snyder, J P, Bussel, J, Balduini, C L, Giannakakou, P, Noris, P
Published in Journal of thrombosis and haemostasis (01.04.2015)
Published in Journal of thrombosis and haemostasis (01.04.2015)
Get full text
Journal Article
Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway
TAN, Chalet, DE NORONHA, Rita G, WEI ZHOU, OLSON, Jeffrey J, PEREIRA, M. Manuela, NICOLAOU, K. C, VAN MEIR, Erwin G, ROECKER, Anthony J, PYRZYNSKA, Beata, KHWAJA, Fatima, ZHAOBIN ZHANG, HUANCHUN ZHANG, QUINCY TENG, NICHOLSON, Ainsley C, GIANNAKAKOU, Paraskevi
Published in Cancer research (Chicago, Ill.) (15.01.2005)
Published in Cancer research (Chicago, Ill.) (15.01.2005)
Get full text
Journal Article