A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; -Roscovitine), administered twice daily for 7 days every 21 days
BENSON, C, WHITE, J, CASSIDY, J, GIANELLA-BORRADORI, A, JUDSON, I, TWELVES, C, DE BONO, J, O'DONNELL, A, RAYNAUD, F, CRUICKSHANK, C, MCGRATH, H, WALTON, M, WORKMAN, P, KAYE, S
Published in British journal of cancer (15.01.2007)
Published in British journal of cancer (15.01.2007)
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Phase 1b trial of atacicept, a recombinant protein binding BLyS and APRIL, in patients with chronic lymphocytic leukemia
Kofler, D M, Gawlik, B B, Elter, T, Gianella-Borradori, A, Wendtner, C-M, Hallek, M
Published in Leukemia (01.04.2012)
Published in Leukemia (01.04.2012)
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A phase I schedule dependency study of the aurora kinase inhibitor MSC1992371A in combination with gemcitabine in patients with solid tumors
Raymond, E., Alexandre, J., Faivre, S., Goldwasser, F., Besse-Hammer, T., Gianella-Borradori, A., Jego, V., Trandafir, L., Rejeb, N., Awada, A.
Published in Investigational new drugs (01.02.2014)
Published in Investigational new drugs (01.02.2014)
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A phase l study of three different dosing schedules of the oral aurora kinase inhibitor MSC1992371A in patients with solid tumors
Mita, M., Gordon, M., Rejeb, N., Gianella-Borradori, A., Jego, V., Mita, A., Sarantopoulos, J., Sankhala, K., Mendelson, D.
Published in Targeted oncology (01.09.2014)
Published in Targeted oncology (01.09.2014)
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In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas
Lacrima, K., Valentini, A., Lambertini, C., Taborelli, M., Rinaldi, A., Zucca, E., Catapano, C., Cavalli, F., Gianella-Borradori, A., MacCallum, D. E., Bertoni, F.
Published in Annals of oncology (01.07.2005)
Published in Annals of oncology (01.07.2005)
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The Human Blue Opsin Promoter Directs Transgene Expression in Short-Wave Cones and Bipolar Cells in the Mouse Retina
Chen, J., Tucker, C. L., Woodford, B., Szel, A., Lem, J., Gianella-Borradori, A., Simon, M. I., Bogenmann, E.
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.1994)
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Conference Proceeding
Immunthrombocytopenic purpura as a model for pathogenesis and treatment of autoimmunity
Imbach, P, Akatsuka, J, Blanchette, V, Burek-Kozlowska, A, Bussel, J, Gaedicke, G, Gianella-Borradori, A, Gugler, E, Hirt, A, Imholz, B
Published in European journal of pediatrics (01.04.1995)
Published in European journal of pediatrics (01.04.1995)
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Efficacy and safety of satralizumab monotherapy for relapse prevention in neuromyelitis optica spectrum disorder (NMOSD): Results from SAkuraStar, a double-blind placebo-controlled phase 3 clinical study
Traboulsee, A., Greenberg, B., Bennett, J.L., Szczechowski, L., Fox, E., Shkrobot, S., Yamamura, T., Terada, Y., Kawata, Y., Wright, P., von Büdingen, H.C., Klingelschmitt, G., Gianella-Borradori, A., Weinshenker, B.G.
Published in Journal of the neurological sciences (15.10.2019)
Published in Journal of the neurological sciences (15.10.2019)
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Efficacy of satralizumab as monotherapy in pre-specified subgroups of SAkuraStar, a double-blind placebo-controlled phase 3 clinical study in patients with neuromyelitis optica spectrum disorder (NMOSD)
Bennett, Jeffrey L., Greenberg, B., Traboulsee, A., Szczechowski, L., Fox, E., Shkrobot, S., Yamamura, T., Terada, Y., Kawata, Y., von Büdingen, H.C., Klingelschmitt, G., Gianella-Borradori, A., Weinshenker, B.G.
Published in Journal of the neurological sciences (15.10.2019)
Published in Journal of the neurological sciences (15.10.2019)
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Seliciclib (CYC202, R-roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1
MACCALLUM, David E, MELVILLE, Jean, FRAME, Sheelagh, WATT, Kathryn, ANDERSON, Sian, GIANELLA-BORRADORI, Athos, LANE, David P, GREEN, Simon R
Published in Cancer research (Chicago, Ill.) (15.06.2005)
Published in Cancer research (Chicago, Ill.) (15.06.2005)
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Phase I study of interleukin-6 in children with solid tumours in relapse
Bouffet, E., Philip, T., Negrier, G., Ffrench, M., Frappaz, D., Gentilhomme, O., Gianella-Borradori, A., Brunat-Mentigny, M., Blay, J.Y.
Published in European journal of cancer (1990) (01.09.1997)
Published in European journal of cancer (1990) (01.09.1997)
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CDK inhibitors in clinical development for the treatment of cancer
Fischer, Peter M, Gianella-Borradori, Athos
Published in Expert opinion on investigational drugs (01.06.2003)
Published in Expert opinion on investigational drugs (01.06.2003)
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Gene therapy for glioblestome multiforme : in vivo tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
STOCKHAMMER, G, BROTCHI, J, YONEKAWA, Y, TWERDY, K, KOSTRON, H, DE WITTE, O, LAMBERMONT, M, VELU, T, LANEUVILLE, P, VILLEMURE, J.-G, RUTKA, J. T, WARNKE, P, LEBLANC, R, LASEUR, M, MOOIJ, J. J. A, BOËTHIUS, J, MARIANI, L, MEYER, M, BRÄNDLI, C, FREI, K, KÖNU, D, GIANELLA-BORRADORI, A, BERNSTEIN, M, SCHACKERT, G, WEBER, F, OSTERTAG, C, MULDER, N. H, MELLSTEDT, H, SEILER, R
Published in Journal of molecular medicine (Berlin, Germany) (14.04.1997)
Published in Journal of molecular medicine (Berlin, Germany) (14.04.1997)
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Reversal of collapsing glomerulopathy in mice with the cyclin-dependent kinase inhibitor CYC202
GHERARDI, Dana, D'AGATI, Vivette, CHU, Te-Hua Tearina, BARNETT, Anna, GIANELLA-BORRADORI, Athos, GELMAN, Irwin H, NELSON, Peter J
Published in Journal of the American Society of Nephrology (01.05.2004)
Published in Journal of the American Society of Nephrology (01.05.2004)
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Antiviral Activity of CYC202 in HIV-1-infected Cells
Agbottah, Emmanuel, de La Fuente, Cynthia, Nekhai, Sergie, Barnett, Anna, Gianella-Borradori, Athos, Pumfery, Anne, Kashanchi, Fatah
Published in The Journal of biological chemistry (28.01.2005)
Published in The Journal of biological chemistry (28.01.2005)
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Abstract 2746: A phase I, dose-escalation study of the Eg5-inhibitor EMD534085 in subjects with advanced solid tumors and lymphoma
Bahleda, Rastilav, Massard, Christophe, Deutsch, Eric, Ribrag, Vincent, Loriot, Yohann, Kroesser, S, Gianella-Borradori, A, Trandafir, L, Soria, Jean-Charles
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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