Genomic complexity of multiple myeloma and its clinical implications
Manier, Salomon, Salem, Karma Z., Park, Jihye, Landau, Dan A., Getz, Gad, Ghobrial, Irene M.
Published in Nature reviews. Clinical oncology (01.02.2017)
Published in Nature reviews. Clinical oncology (01.02.2017)
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The BTK inhibitor ibrutinib may protect against pulmonary injury in COVID-19–infected patients
Treon, Steven P., Castillo, Jorge J., Skarbnik, Alan P., Soumerai, Jacob D., Ghobrial, Irene M., Guerrera, Maria Luisa, Meid, Kirsten, Yang, Guang
Published in Blood (21.05.2020)
Published in Blood (21.05.2020)
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Multiple Myeloma and the Immune Microenvironment
Kawano, Yawara, Roccaro, Aldo M, Ghobrial, Irene M, Azzi, Jamil
Published in Current cancer drug targets (01.01.2017)
Published in Current cancer drug targets (01.01.2017)
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Bone marrow niches in haematological malignancies
Méndez-Ferrer, Simón, Bonnet, Dominique, Steensma, David P., Hasserjian, Robert P., Ghobrial, Irene M., Gribben, John G., Andreeff , Michael, Krause, Daniela S.
Published in Nature reviews. Cancer (01.05.2020)
Published in Nature reviews. Cancer (01.05.2020)
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Targeting the bone marrow microenvironment in multiple myeloma
Kawano, Yawara, Moschetta, Michele, Manier, Salomon, Glavey, Siobhan, Görgün, Güllü T., Roccaro, Aldo M., Anderson, Kenneth C., Ghobrial, Irene M.
Published in Immunological reviews (01.01.2015)
Published in Immunological reviews (01.01.2015)
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Prognostic role of circulating exosomal miRNAs in multiple myeloma
Manier, Salomon, Liu, Chia-Jen, Avet-Loiseau, Hervé, Park, Jihye, Shi, Jiantao, Campigotto, Federico, Salem, Karma Z., Huynh, Daisy, Glavey, Siobhan V., Rivotto, Bradley, Sacco, Antonio, Roccaro, Aldo M., Bouyssou, Juliette, Minvielle, Stéphane, Moreau, Philippe, Facon, Thierry, Leleu, Xavier, Weller, Edie, Trippa, Lorenzo, Ghobrial, Irene M.
Published in Blood (27.04.2017)
Published in Blood (27.04.2017)
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The microenvironment in myeloma
Lomas, Oliver C, Tahri, Sabrin, Ghobrial, Irene M
Published in Current opinion in oncology (01.03.2020)
Published in Current opinion in oncology (01.03.2020)
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Mitochondrial metabolism promotes adaptation to proteotoxic stress
Tsvetkov, Peter, Detappe, Alexandre, Cai, Kai, Keys, Heather R., Brune, Zarina, Ying, Weiwen, Thiru, Prathapan, Reidy, Mairead, Kugener, Guillaume, Rossen, Jordan, Kocak, Mustafa, Kory, Nora, Tsherniak, Aviad, Santagata, Sandro, Whitesell, Luke, Ghobrial, Irene M., Markley, John L., Lindquist, Susan, Golub, Todd R.
Published in Nature chemical biology (01.07.2019)
Published in Nature chemical biology (01.07.2019)
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Molecular bottlebrush prodrugs as mono- and triplex combination therapies for multiple myeloma
Detappe, Alexandre, Nguyen, Hung V.-T., Jiang, Yivan, Agius, Michael P., Wang, Wencong, Mathieu, Clelia, Su, Nang K., Kristufek, Samantha L., Lundberg, David J., Bhagchandani, Sachin, Ghobrial, Irene M., Ghoroghchian, P. Peter, Johnson, Jeremiah A.
Published in Nature nanotechnology (01.02.2023)
Published in Nature nanotechnology (01.02.2023)
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The bone-marrow niche in MDS and MGUS: implications for AML and MM
Ghobrial, Irene M., Detappe, Alexandre, Anderson, Kenneth C., Steensma, David P.
Published in Nature reviews. Clinical oncology (01.04.2018)
Published in Nature reviews. Clinical oncology (01.04.2018)
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Metabolic signature identifies novel targets for drug resistance in multiple myeloma
Maiso, Patricia, Huynh, Daisy, Moschetta, Michele, Sacco, Antonio, Aljawai, Yosra, Mishima, Yuji, Asara, John M, Roccaro, Aldo M, Kimmelman, Alec C, Ghobrial, Irene M
Published in Cancer research (Chicago, Ill.) (15.05.2015)
Published in Cancer research (Chicago, Ill.) (15.05.2015)
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Single-cell profiling of tumour evolution in multiple myeloma — opportunities for precision medicine
Dutta, Ankit K., Alberge, Jean-Baptiste, Sklavenitis-Pistofidis, Romanos, Lightbody, Elizabeth D., Getz, Gad, Ghobrial, Irene M.
Published in Nature reviews. Clinical oncology (01.04.2022)
Published in Nature reviews. Clinical oncology (01.04.2022)
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Long-Term Follow-Up of Ibrutinib Monotherapy in Symptomatic, Previously Treated Patients With Waldenström Macroglobulinemia
Treon, Steven P, Meid, Kirsten, Gustine, Joshua, Yang, Guang, Xu, Lian, Liu, Xia, Patterson, Christopher J, Hunter, Zachary R, Branagan, Andrew R, Laubach, Jacob P, Ghobrial, Irene M, Palomba, M Lia, Advani, Ranjana, Castillo, Jorge J
Published in Journal of clinical oncology (20.02.2021)
Published in Journal of clinical oncology (20.02.2021)
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BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
Delmore, Jake E., Issa, Ghayas C., Lemieux, Madeleine E., Rahl, Peter B., Shi, Junwei, Jacobs, Hannah M., Kastritis, Efstathios, Gilpatrick, Timothy, Paranal, Ronald M., Qi, Jun, Chesi, Marta, Schinzel, Anna C., McKeown, Michael R., Heffernan, Timothy P., Vakoc, Christopher R., Bergsagel, P. Leif, Ghobrial, Irene M., Richardson, Paul G., Young, Richard A., Hahn, William C., Anderson, Kenneth C., Kung, Andrew L., Bradner, James E., Mitsiades, Constantine S.
Published in Cell (16.09.2011)
Published in Cell (16.09.2011)
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Genome instability in multiple myeloma
Neuse, Carl Jannes, Lomas, Oliver C., Schliemann, Christoph, Shen, Yu Jia, Manier, Salomon, Bustoros, Mark, Ghobrial, Irene M.
Published in Leukemia (01.11.2020)
Published in Leukemia (01.11.2020)
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BM mesenchymal stromal cell-derived exosomes facilitate multiple myeloma progression
Roccaro, Aldo M, Sacco, Antonio, Maiso, Patricia, Azab, Abdel Kareem, Tai, Yu-Tzu, Reagan, Michaela, Azab, Feda, Flores, Ludmila M, Campigotto, Federico, Weller, Edie, Anderson, Kenneth C, Scadden, David T, Ghobrial, Irene M
Published in The Journal of clinical investigation (01.04.2013)
Published in The Journal of clinical investigation (01.04.2013)
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