Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy
Becker, Daniel P, Villamil, Clara I, Barta, Thomas E, Bedell, Louis J, Boehm, Terri L, DeCrescenzo, Gary A, Freskos, John N, Getman, Daniel P, Hockerman, Susan, Heintz, Robert, Howard, Susan Carol, Li, Madeleine H, McDonald, Joseph J, Carron, Chris P, Funckes-Shippy, Chris L, Mehta, Pramod P, Munie, Grace E, Swearingen, Craig A
Published in Journal of medicinal chemistry (20.10.2005)
Published in Journal of medicinal chemistry (20.10.2005)
Get full text
Journal Article
Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease
Nagarajan, Srinivasan R, De Crescenzo, Gary A, Getman, Daniel P, Lu, Hwang-Fun, Sikorski, James A, Walker, Jeffrey L, McDonald, Joseph J, Houseman, Kathryn A, Kocan, Geralyn P, Kishore, Nandini, Mehta, Pramod P, Funkes-Shippy, Christie L, Blystone, Lisa
Published in Bioorganic & medicinal chemistry (03.11.2003)
Published in Bioorganic & medicinal chemistry (03.11.2003)
Get full text
Journal Article
α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1
Becker, Daniel P, Barta, Thomas E, Bedell, Louis, DeCrescenzo, Gary, Freskos, John, Getman, Daniel P, Hockerman, Susan L, Li, Madeleine, Mehta, Pramod, Mischke, Brent, Munie, Grace E, Swearingen, Craig, Villamil, Clara I
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Get full text
Journal Article
Discovery of a novel class of potent HIV-1 protease inhibitors containing the (R)-(hydroxyethyl)urea isostere
Getman, Daniel P, DeCrescenzo, Gary A, Heintz, Robert M, Reed, Kathryn L, Talley, John J, Bryant, Martin L, Clare, Michael, Houseman, Kathryn A, Marr, J. Joseph
Published in Journal of medicinal chemistry (1993)
Published in Journal of medicinal chemistry (1993)
Get full text
Journal Article
α-Alkyl-α-amino-β-sulphone hydroxamates as potent MMP inhibitors that spare MMP-1
Becker, Daniel P, DeCrescenzo, Gary, Freskos, John, Getman, Daniel P, Hockerman, Susan L, Li, Madeleine, Mehta, Pramod, Munie, Grace E, Swearingen, Craig
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Published in Bioorganic & medicinal chemistry letters (22.10.2001)
Get full text
Journal Article
Design and Synthesis of Novel Imidazole-Substituted Dipeptide Amides as Potent and Selective Inhibitors of Candida albicans MyristoylCoA:Protein N-Myristoyltransferase and Identification of Related Tripeptide Inhibitors with Mechanism-Based Antifungal Activity
Devadas, Balekudru, Freeman, Sandra K, Zupec, Mark E, Lu, Hwang-Fun, Nagarajan, Srinivasan R, Kishore, Nandini S, Lodge, Jennifer K, Kuneman, David W, McWherter, Charles A, Vinjamoori, Dutt V, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (01.08.1997)
Published in Journal of medicinal chemistry (01.08.1997)
Get full text
Journal Article
Design and Syntheses of Potent and Selective Dipeptide Inhibitors of Candida albicans Myristoyl-CoA:Protein N-Myristoyltransferase
Devadas, Balekudru, Zupec, Mark E, Freeman, Sandra K, Brown, David L, Nagarajan, Srinivasan, Sikorski, James A, McWherter, Charles A, Getman, Daniel P, Gordon, Jeffrey I
Published in Journal of medicinal chemistry (01.05.1995)
Published in Journal of medicinal chemistry (01.05.1995)
Get full text
Journal Article
DPC 681 and DPC 684: Potent, Selective Inhibitors of Human Immunodeficiency Virus Protease Active against Clinically Relevant Mutant Variants
KALTENBACH, Robert F, TRAINOR, George, KLABE, Ronald, DIAMOND, Sharon, DAVIES, Marc, SAYE, Joanne, JONA, Ianan, ERICKSON-VIITANEN, Susan, GETMAN, Daniel, HARRIS, Greg, GARBER, Sena, CORDOVA, Beverly, BACHELER, Lee, JEFFREY, Susan, LOGUE, Kelly, CAWOOD, Pamela
Published in Antimicrobial Agents and Chemotherapy (01.11.2001)
Published in Antimicrobial Agents and Chemotherapy (01.11.2001)
Get full text
Journal Article
Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: Protein N-myristoyltransferase: A new approach to antifungal therapy
Sikorski, James A., Devadas, Balekudru, Zupec, Mark E., Freeman, Sandra K., Brown, David L., Lu, Hwang-Fun, Nagarajan, Srinivasan, Mehta, Pramod P., Wade, Arlene C., Kishore, Nandini S., Bryant, Martin L., Getman, Daniel P., McWherter, Charles A., Gordon, Jeffrey I.
Published in Biopolymers (1997)
Published in Biopolymers (1997)
Get full text
Journal Article
Conformationally Constrained [p-(ω-Aminoalkyl)phenacetyl]-l-seryl-l-lysyl Dipeptide Amides as Potent Peptidomimetic Inhibitors of Candida albicans and Human Myristoyl-CoA:Protein N-Myristoyl Transferase
Nagarajan, Srinivasan R, Devadas, Balekudru, Zupec, Mark E, Freeman, Sandra K, Brown, David L, Lu, Hwang-Fun, Mehta, Pramod P, Kishore, Nandini S, McWherter, Charles A, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (09.05.1997)
Published in Journal of medicinal chemistry (09.05.1997)
Get full text
Journal Article
N-Myristoylation of Arf proteins in Candida albicans: an in vivo assay for evaluating antifungal inhibitors of myristoyl-CoA:protein N-myristoyltransferase
Lodge, Jennifer K, Jackson-Machelski, Emily, Devadas, Balekudru, Zupec, Mark E, Getman, Daniel P, Kishore, Nandini, Freeman, Sandra K, McWherter, Charles A, Sikorski, James A, Gordon, Jeffrey I
Published in Microbiology (Society for General Microbiology) (01.02.1997)
Published in Microbiology (Society for General Microbiology) (01.02.1997)
Get full text
Journal Article
Scanning Alanine Mutagenesis and De-peptidization of a Candida albicans Myristoyl-CoA:ProteinN-Myristoyltransferase Octapeptide Substrate Reveals Three Elements Critical for Molecular Recognition
McWherter, Charles A., Rocque, Warren J., Zupec, Mark E., Freeman, Sandra K., Brown, David L., Devadas, Balekudru, Getman, Daniel P., Sikorski, James A., Gordon, Jeffrey I.
Published in The Journal of biological chemistry (01.05.1997)
Published in The Journal of biological chemistry (01.05.1997)
Get full text
Journal Article
Hydroxyethylamino sulfonamides useful as retroviral protease inhibitors
JOHN J TALLEY JOHN J TALLEY, JOHN N FRESKOS JOHN N FRESKOS, MICHAEL L VAZQUEZ MICHAEL L VAZQUEZ, GARY A DECRESCENZO GARY A DECRESCENZO, RICHARD A. MUELLER RICHARD A. MUELLER, DANIEL GETMAN DANIEL GETMAN
Year of Publication 17.05.2007
Get full text
Year of Publication 17.05.2007
Patent
BROADSPECTRUM 2-AMINO-BENZOTHIAZOLE SULFONAMIDE HIV PROTEASE INHIBITORS
WIGERINCK PIET TOM BERT PAUL, SURLERAUX DOMINIQUE LOUIS NESTOR GHISLAIN, GETMAN DANIEL P
Year of Publication 30.12.2010
Get full text
Year of Publication 30.12.2010
Patent
Suicide inhibition of canine myocardial cytosolic calcium-independent phospholipase A2. Mechanism-based discrimination between calcium-dependent and -independent phospholipases A2
Hazen, S L, Zupan, L A, Weiss, R H, Getman, D P, Gross, R W
Published in The Journal of biological chemistry (15.04.1991)
Published in The Journal of biological chemistry (15.04.1991)
Get full text
Journal Article
Photochemical transformations of small ring compounds. 95. The problem of regioselectivity in the photochemical ring-opening reaction of 3-phenyl- and 3-vinyl-substituted cyclopropenes to indenes and 1,3-cyclopentadienes
Padwa, Albert, Blacklock, Thomas J, Getman, Daniel, Hatanaka, Naoto, Loza, Roman
Published in Journal of organic chemistry (01.04.1978)
Published in Journal of organic chemistry (01.04.1978)
Get full text
Journal Article
Hydroxyethylaminosulfaminsyrederivater til anvendelse som inhibitorer af retrovirale proteaser
MUELLER, RICHARD, A, TALLEY, JOHN, J, SUN, ERIC, T, SUN, ERIC, T. 7614 PALMILLA DRIVE, GETMAN, DANIEL, VAZQUEZ, MICHAEL, L, GETMAN, DANIEL, P, DECRESCENZO, GARY, A
Year of Publication 02.11.1998
Get full text
Year of Publication 02.11.1998
Patent