Safety, Tolerability, and Pharmacokinetics of Remdesivir, An Antiviral for Treatment of COVID‐19, in Healthy Subjects
Humeniuk, Rita, Mathias, Anita, Cao, Huyen, Osinusi, Anu, Shen, Gong, Chng, Estelle, Ling, John, Vu, Amanda, German, Polina
Published in Clinical and Translational Science (01.09.2020)
Published in Clinical and Translational Science (01.09.2020)
Get full text
Journal Article
Web Resource
Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor
Humeniuk, Rita, Mathias, Anita, Kirby, Brian J., Lutz, Justin D., Cao, Huyen, Osinusi, Anu, Babusis, Darius, Porter, Danielle, Wei, Xuelian, Ling, John, Reddy, Y. Sunila, German, Polina
Published in Clinical pharmacokinetics (01.05.2021)
Published in Clinical pharmacokinetics (01.05.2021)
Get full text
Journal Article
Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1
Naggie, Susanna, Cooper, Curtis, Saag, Michael, Workowski, Kimberly, Ruane, Peter, Towner, William J, Marks, Kristen, Luetkemeyer, Anne, Baden, Rachel P, Sax, Paul E, Gane, Edward, Santana-Bagur, Jorge, Stamm, Luisa M, Yang, Jenny C, German, Polina, Dvory-Sobol, Hadas, Ni, Liyun, Pang, Phillip S, McHutchison, John G, Stedman, Catherine A.M, Morales-Ramirez, Javier O, Bräu, Norbert, Jayaweera, Dushyantha, Colson, Amy E, Tebas, Pablo, Wong, David K, Dieterich, Douglas, Sulkowski, Mark
Published in The New England journal of medicine (20.08.2015)
Published in The New England journal of medicine (20.08.2015)
Get full text
Journal Article
A Phase 2, Randomized, Double-blind, Placebo-Controlled Trial of Presatovir for the Treatment of Respiratory Syncytial Virus Upper Respiratory Tract Infection in Hematopoietic-Cell Transplant Recipients
Chemaly, Roy F, Dadwal, Sanjeet S, Bergeron, Anne, Ljungman, Per, Kim, Yae-Jean, Cheng, Guang-Shing, Pipavath, Sudhakar N, Limaye, Ajit P, Blanchard, Elodie, Winston, Drew J, Stiff, Patrick J, Zuckerman, Tsila, Lachance, Silvy, Rahav, Galia, Small, Catherine B, Mullane, Kathleen M, Patron, Roberto L, Lee, Dong-Gun, Hirsch, Hans H, Waghmare, Alpana, McKevitt, Matt, Jordan, Robert, Guo, Ying, German, Polina, Porter, Danielle P, Gossage, David L, Watkins, Timothy R, Marty, Francisco M, Chien, Jason W, Boeckh, Michael
Published in Clinical infectious diseases (31.12.2020)
Published in Clinical infectious diseases (31.12.2020)
Get full text
Journal Article
Drug–Drug Interaction Profile of the Fixed-Dose Combination Tablet Regimen Ledipasvir/Sofosbuvir
German, Polina, Mathias, Anita, Brainard, Diana M., Kearney, Brian P.
Published in Clinical pharmacokinetics (01.11.2018)
Published in Clinical pharmacokinetics (01.11.2018)
Get full text
Journal Article
Use of Multiple Probes to Assess Transporter- and Cytochrome P450-Mediated Drug–Drug Interaction Potential of the Pangenotypic HCV NS5A Inhibitor Velpatasvir
Mogalian, Erik, German, Polina, Kearney, Brian P., Yang, Cheng Yong, Brainard, Diana, McNally, John, Moorehead, Lisa, Mathias, Anita
Published in Clinical pharmacokinetics (01.05.2016)
Published in Clinical pharmacokinetics (01.05.2016)
Get full text
Journal Article
Pharmacokinetics, disposition, and biotransformation of the cardiac myosin inhibitor aficamten in humans
Xu, Donghong, Divanji, Punag, Griffith, Adrienne, Sukhun, Rajaa, Cheplo, Kathleen, Li, Jianlin, German, Polina
Published in Pharmacology research & perspectives (01.10.2024)
Published in Pharmacology research & perspectives (01.10.2024)
Get full text
Journal Article
Pharmacokinetics of Artemether-Lumefantrine and Artesunate-Amodiaquine in Children in Kampala, Uganda
MWESIGWA, Julia, PARIKH, Sunil, ROSENTHAL, Philip J, KAMYA, Moses R, AWEEKA, Francesca, MCGEE, Bryan, GERMAN, Polina, DRYSDALE, Troy, KALYANGO, Joan N, CLARK, Tamara D, DORSEY, Grant, LINDEGARDH, Niklas, ANNERBERG, Anna
Published in Antimicrobial Agents and Chemotherapy (01.01.2010)
Published in Antimicrobial Agents and Chemotherapy (01.01.2010)
Get full text
Journal Article
P-6 SOFOSBUVIR CONTAINING REGIMENS ARE SAFE AND EFFECTIVE IN ADOLESCENTS WITH CHRONIC HEPATITIS C INFECTION
Wirth, Stefan, Gonzalez-Peralta, Regino, Rosenthal, Philip, Hardikar, Winita, Wen, Jessica, Jonas, Maureen M., Mittal, Naveen, Whitworth, Mary, Arnon, Ronen, Lin, Chuan-Hao, Lobzin, Yury, Romero, Rene, Chulanov, Vladimir, Subbarao, Girish, Teckman, Jeffrey, Morozov, Vyacheslav, Bassetti, Eric, Kersey, Kathryn, Massetto, Benedetta, Zhu, Yanni, German, Polina, Brainard, Diana M., Bansal, Sanjay, Murray, Karen F., Schwarz, Kathleen, Balistreri, William
Published in Annals of hepatology (01.09.2021)
Published in Annals of hepatology (01.09.2021)
Get full text
Journal Article
Hepatotoxicity Due to a Drug Interaction between Amodiaquine plus Artesunate and Efavirenz
German, Polina, Greenhouse, Bryan, Coates, Carrie, Dorsey, Grant, Rosenthal, Philip J., Charlebois, Edwin, Lindegardh, Niklas, Havlir, Diane, Aweeka, Francesca T.
Published in Clinical infectious diseases (15.03.2007)
Published in Clinical infectious diseases (15.03.2007)
Get full text
Journal Article
Physiologically-Based Pharmacokinetic Modeling of Remdesivir and Its Metabolites to Support Dose Selection for the Treatment of Pediatric Patients With COVID-19
Lutz, Justin D, Mathias, Anita, German, Polina, Pikora, Cheryl, Reddy, Sunila, Kirby, Brian J
Published in Clinical Pharmacology & Therapeutics (01.04.2021)
Published in Clinical Pharmacology & Therapeutics (01.04.2021)
Get full text
Journal Article
Web Resource
Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies
Xiao, Deqing, John Ling, Kah Hiing, Tarnowski, Thomas, Humeniuk, Rita, German, Polina, Mathias, Anita, Chu, Jasper, Chen, Yuan-Shek, van Ingen, Eric
Published in Analytical biochemistry (15.03.2021)
Published in Analytical biochemistry (15.03.2021)
Get full text
Journal Article
The safety and effectiveness of ledipasvir−sofosbuvir in adolescents 12‐17 years old with hepatitis C virus genotype 1 infection
Balistreri, William F., Murray, Karen F., Rosenthal, Philip, Bansal, Sanjay, Lin, Chuan‐Hao, Kersey, Kathryn, Massetto, Benedetta, Zhu, Yanni, Kanwar, Bittoo, German, Polina, Svarovskaia, Evguenia, Brainard, Diana M., Wen, Jessica, Gonzalez‐Peralta, Regino P., Jonas, Maureen M., Schwarz, Kathleen
Published in Hepatology (Baltimore, Md.) (01.08.2017)
Published in Hepatology (Baltimore, Md.) (01.08.2017)
Get full text
Journal Article
Effect of cobicistat on glomerular filtration rate in subjects with normal and impaired renal function
German, Polina, Liu, Hui C, Szwarcberg, Javier, Hepner, Mischa, Andrews, Jessica, Kearney, Brian P, Mathias, Anita
Published in Journal of acquired immune deficiency syndromes (1999) (01.09.2012)
Published in Journal of acquired immune deficiency syndromes (1999) (01.09.2012)
Get more information
Journal Article
Vesatolimod, a Toll-like Receptor 7 Agonist, Induces Immune Activation in Virally Suppressed Adults Living With Human Immunodeficiency Virus–1
Riddler, Sharon A, Para, Michael, Benson, Constance A, Mills, Anthony, Ramgopal, Moti, DeJesus, Edwin, Brinson, Cynthia, Cyktor, Joshua, Jacobs, Jana, Koontz, Dianna, Mellors, John W, Laird, Gregory M, Wrin, Terri, Patel, Heena, Guo, Susan, Wallin, Jeffrey, Boice, Jillian, Zhang, Liao, Humeniuk, Rita, Begley, Rebecca, German, Polina, Graham, Hiba, Geleziunas, Romas, Brainard, Diana M, SenGupta, Devi
Published in Clinical infectious diseases (01.06.2021)
Published in Clinical infectious diseases (01.06.2021)
Get full text
Journal Article
Preclinical Pharmacokinetics and First-in-Human Pharmacokinetics, Safety, and Tolerability of Velpatasvir, a Pangenotypic Hepatitis C Virus NS5A Inhibitor, in Healthy Subjects
Mogalian, Erik, German, Polina, Kearney, Brian P, Yang, Cheng Yong, Brainard, Diana, Link, John, McNally, John, Han, LingLing, Ling, John, Mathias, Anita
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Get full text
Journal Article