Full activation of thermogenesis in brown adipocytes requires Basigin action
Rupar, Kaja, Isidor, Marie S., Argemi‐Muntadas, Lidia, Agueda‐Oyarzabal, Marina, Plucińska, Kaja, Brown, Erin L., Mattanovich, Matthias, Bossi, Simone, Tozzi, Marco, Tandio, David, Petersen, Patricia S. S., Henriksen, Tora I., Trošt, Kajetan, Hansen, Jacob B., Gerhart‐Hines, Zachary, Nielsen, Søren, Moritz, Thomas, Emanuelli, Brice
Published in The FEBS journal (01.05.2023)
Published in The FEBS journal (01.05.2023)
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Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue
Lundh, Morten, Petersen, Patricia SS, Isidor, Marie S, Kazoka‐Sørensen, Dolly NM, Plucińska, Kaja, Shamsi, Farnaz, Ørskov, Cathrine, Tozzi, Marco, Brown, Erin L, Andersen, Emil, Ma, Tao, Müller, Ulrich, Barrès, Romain, Kristiansen, Viggo B, Gerhart‐Hines, Zachary, Tseng, Yu‐Hua, Emanuelli, Brice
Published in EMBO reports (01.08.2019)
Published in EMBO reports (01.08.2019)
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Fueling the fire of adipose thermogenesis
Wolfrum, Christian, Gerhart-Hines, Zachary
Published in Science (American Association for the Advancement of Science) (18.03.2022)
Published in Science (American Association for the Advancement of Science) (18.03.2022)
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Role of Energy Excretion in Human Body Weight Regulation
Lund, Jens, Gerhart-Hines, Zachary, Clemmensen, Christoffer
Published in Trends in endocrinology and metabolism (01.10.2020)
Published in Trends in endocrinology and metabolism (01.10.2020)
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Circadian Enhancers Coordinate Multiple Phases of Rhythmic Gene Transcription In Vivo
Fang, Bin, Everett, Logan J., Jager, Jennifer, Briggs, Erika, Armour, Sean M., Feng, Dan, Roy, Ankur, Gerhart-Hines, Zachary, Sun, Zheng, Lazar, Mitchell A.
Published in Cell (20.11.2014)
Published in Cell (20.11.2014)
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Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α
Gerhart-Hines, Zachary, Rodgers, Joseph T, Bare, Olivia, Lerin, Carles, Kim, Seung-Hee, Mostoslavsky, Raul, Alt, Frederick W, Wu, Zhidan, Puigserver, Pere
Published in The EMBO journal (04.04.2007)
Published in The EMBO journal (04.04.2007)
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Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine
Deshmukh, Atul S, Peijs, Lone, Beaudry, Jacqueline L, Jespersen, Naja Z, Nielsen, Carsten H, Ma, Tao, Brunner, Andreas D, Larsen, Therese J, Bayarri-Olmos, Rafael, Prabhakar, Bhargav S, Helgstrand, Charlotte, Severinsen, Mai C K, Holst, Birgitte, Kjaer, Andreas, Tang-Christensen, Mads, Sanfridson, Annika, Garred, Peter, Privé, Gilbert G, Pedersen, Bente K, Gerhart-Hines, Zachary, Nielsen, Søren, Drucker, Daniel J, Mann, Matthias, Scheele, Camilla
Published in Cell metabolism (05.11.2019)
Published in Cell metabolism (05.11.2019)
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Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling
Khatib-Massalha, Eman, Bhattacharya, Suditi, Massalha, Hassan, Biram, Adi, Golan, Karin, Kollet, Orit, Kumari, Anju, Avemaria, Francesca, Petrovich-Kopitman, Ekaterina, Gur-Cohen, Shiri, Itkin, Tomer, Brandenburger, Isabell, Spiegel, Asaf, Shulman, Ziv, Gerhart-Hines, Zachary, Itzkovitz, Shalev, Gunzer, Matthias, Offermanns, Stefan, Alon, Ronen, Ariel, Amiram, Lapidot, Tsvee
Published in Nature communications (15.07.2020)
Published in Nature communications (15.07.2020)
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Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation
Agudelo, Leandro Z., Ferreira, Duarte M.S., Cervenka, Igor, Bryzgalova, Galyna, Dadvar, Shamim, Jannig, Paulo R., Pettersson-Klein, Amanda T., Lakshmikanth, Tadepally, Sustarsic, Elahu G., Porsmyr-Palmertz, Margareta, Correia, Jorge C., Izadi, Manizheh, Martínez-Redondo, Vicente, Ueland, Per M., Midttun, Øivind, Gerhart-Hines, Zachary, Brodin, Petter, Pereira, Teresa, Berggren, Per-Olof, Ruas, Jorge L.
Published in Cell metabolism (06.02.2018)
Published in Cell metabolism (06.02.2018)
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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Sveidahl Johansen, Olivia, Ma, Tao, Hansen, Jakob Bondo, Markussen, Lasse Kruse, Schreiber, Renate, Reverte-Salisa, Laia, Dong, Hua, Christensen, Dan Ploug, Sun, Wenfei, Gnad, Thorsten, Karavaeva, Iuliia, Nielsen, Thomas Svava, Kooijman, Sander, Cero, Cheryl, Dmytriyeva, Oksana, Shen, Yachen, Razzoli, Maria, O’Brien, Shannon L., Kuipers, Eline N., Nielsen, Carsten Haagen, Orchard, William, Willemsen, Nienke, Jespersen, Naja Zenius, Lundh, Morten, Sustarsic, Elahu Gosney, Hallgren, Cecilie Mørch, Frost, Mikkel, McGonigle, Seth, Isidor, Marie Sophie, Broholm, Christa, Pedersen, Oluf, Hansen, Jacob Bo, Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, James G., Babu, M. Madan, Calebiro, Davide, Nielsen, Søren, Rydén, Mikael, Soccio, Raymond, Rensen, Patrick C.N., Treebak, Jonas Thue, Schwartz, Thue Walter, Emanuelli, Brice, Bartolomucci, Alessandro, Pfeifer, Alexander, Zechner, Rudolf, Scheele, Camilla, Mandrup, Susanne, Gerhart-Hines, Zachary
Published in Cell (24.06.2021)
Published in Cell (24.06.2021)
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
Sustarsic, Elahu G., Ma, Tao, Lynes, Matthew D., Larsen, Michael, Karavaeva, Iuliia, Havelund, Jesper F., Nielsen, Carsten H., Jedrychowski, Mark P., Moreno-Torres, Marta, Lundh, Morten, Plucinska, Kaja, Jespersen, Naja Z., Grevengoed, Trisha J., Kramar, Barbara, Peics, Julia, Hansen, Jakob B., Shamsi, Farnaz, Forss, Isabel, Neess, Ditte, Keipert, Susanne, Wang, Jianing, Stohlmann, Katharina, Brandslund, Ivan, Christensen, Cramer, Jørgensen, Marit E., Linneberg, Allan, Pedersen, Oluf, Kiebish, Michael A., Qvortrup, Klaus, Han, Xianlin, Pedersen, Bente Klarlund, Jastroch, Martin, Mandrup, Susanne, Kjær, Andreas, Gygi, Steven P., Hansen, Torben, Gillum, Matthew P., Grarup, Niels, Emanuelli, Brice, Nielsen, Søren, Scheele, Camilla, Tseng, Yu-Hua, Færgeman, Nils J., Gerhart-Hines, Zachary
Published in Cell metabolism (03.07.2018)
Published in Cell metabolism (03.07.2018)
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Housing temperature influences exercise training adaptations in mice
Raun, Steffen H, Henriquez-Olguín, Carlos, Karavaeva, Iuliia, Ali, Mona, Møller, Lisbeth L V, Kot, Witold, Castro-Mejía, Josué L, Nielsen, Dennis Sandris, Gerhart-Hines, Zachary, Richter, Erik A, Sylow, Lykke
Published in Nature communications (25.03.2020)
Published in Nature communications (25.03.2020)
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The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD
Gerhart-Hines, Zachary, Dominy, John E., Blättler, Sharon M., Jedrychowski, Mark P., Banks, Alexander S., Lim, Ji-Hong, Chim, Helen, Gygi, Steven P., Puigserver, Pere
Published in Molecular cell (23.12.2011)
Published in Molecular cell (23.12.2011)
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Lipolysis regulates major transcriptional programs in brown adipocytes
Markussen, Lasse K, Rondini, Elizabeth A, Johansen, Olivia Sveidahl, Madsen, Jesper G S, Sustarsic, Elahu G, Marcher, Ann-Britt, Hansen, Jacob B, Gerhart-Hines, Zachary, Granneman, James G, Mandrup, Susanne
Published in Nature communications (08.07.2022)
Published in Nature communications (08.07.2022)
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A metabolic prosurvival role for PML in breast cancer
Carracedo, Arkaitz, Weiss, Dror, Leliaert, Amy K, Bhasin, Manoj, de Boer, Vincent C J, Laurent, Gaelle, Adams, Andrew C, Sundvall, Maria, Song, Su Jung, Ito, Keisuke, Finley, Lydia S, Egia, Ainara, Libermann, Towia, Gerhart-Hines, Zachary, Puigserver, Pere, Haigis, Marcia C, Maratos-Flier, Elefteria, Richardson, Andrea L, Schafer, Zachary T, Pandolfi, Pier P
Published in The Journal of clinical investigation (01.09.2012)
Published in The Journal of clinical investigation (01.09.2012)
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Thyroid hormone receptor α in skeletal muscle is essential for T3‐mediated increase in energy expenditure
Nicolaisen, Trine S., Klein, Anders B., Dmytriyeva, Oksana, Lund, Jens, Ingerslev, Lars R., Fritzen, Andreas M., Carl, Christian S., Lundsgaard, Anne‐Marie, Frost, Mikkel, Ma, Tao, Schjerling, Peter, Gerhart‐Hines, Zachary, Flamant, Frederic, Gauthier, Karine, Larsen, Steen, Richter, Erik A., Kiens, Bente, Clemmensen, Christoffer
Published in The FASEB journal (01.11.2020)
Published in The FASEB journal (01.11.2020)
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Journal Article
Leveraging GPCR signaling in thermogenic fat to counteract metabolic diseases
Sveidahl Johansen, Olivia, Ma, Tao, Gerhart-Hines, Zachary
Published in Molecular metabolism (Germany) (01.06.2022)
Published in Molecular metabolism (Germany) (01.06.2022)
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Journal Article
Cold-Activated Lipid Dynamics in Adipose Tissue Highlights a Role for Cardiolipin in Thermogenic Metabolism
Lynes, Matthew D., Shamsi, Farnaz, Sustarsic, Elahu Gosney, Leiria, Luiz O., Wang, Chih-Hao, Su, Sheng-Chiang, Huang, Tian Lian, Gao, Fei, Narain, Niven R., Chen, Emily Y., Cypess, Aaron M., Schulz, Tim J., Gerhart-Hines, Zachary, Kiebish, Michael A., Tseng, Yu-Hua
Published in Cell reports (Cambridge) (17.07.2018)
Published in Cell reports (Cambridge) (17.07.2018)
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Journal Article
A Diurnal Rhythm in Brown Adipose Tissue Causes Rapid Clearance and Combustion of Plasma Lipids at Wakening
van den Berg, Rosa, Kooijman, Sander, Noordam, Raymond, Ramkisoensing, Ashna, Abreu-Vieira, Gustavo, Tambyrajah, Lauren L., Dijk, Wieneke, Ruppert, Philip, Mol, Isabel M., Kramar, Barbara, Caputo, Rosanna, Puig, Laura Sardón, de Ruiter, Evelien M., Kroon, Jan, Hoekstra, Menno, van der Sluis, Ronald J., Meijer, Onno C., Willems van Dijk, Ko, van Kerkhof, Linda W.M., Christodoulides, Constantinos, Karpe, Fredrik, Gerhart-Hines, Zachary, Kersten, Sander, Meijer, Johanna H., Coomans, Claudia P., van Heemst, Diana, Biermasz, Nienke R., Rensen, Patrick C.N.
Published in Cell reports (Cambridge) (27.03.2018)
Published in Cell reports (Cambridge) (27.03.2018)
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