A Formal [3 + 3] Cycloaddition Reaction. 5. An Enantioselective Intramolecular Formal Aza-[3 + 3] Cycloaddition Reaction Promoted by Chiral Amine Salts
Gerasyuto, Aleksey I, Hsung, Richard P, Sydorenko, Nadiya, Slafer, Brian
Published in Journal of organic chemistry (27.05.2005)
Published in Journal of organic chemistry (27.05.2005)
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AutoDesigner - Core Design, a De Novo Design Algorithm for Chemical Scaffolds: Application to the Design and Synthesis of Novel Selective Wee1 Inhibitors
Bos, Pieter H, Ranalli, Fabio, Flood, Emelie, Watts, Shawn, Inoyama, Daigo, Knight, Jennifer L, Clark, Anthony J, Placzeck, Andrew, Wang, Jiashi, Gerasyuto, Aleksey I, Silvergleid, Sarah, Yin, Wu, Sun, Shaoxian, Abel, Robert, Bhat, Sathesh
Published in Journal of chemical information and modeling (03.10.2024)
Published in Journal of chemical information and modeling (03.10.2024)
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Discovery and Optimization of Indolyl-Containing 4‑Hydroxy-2-Pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-negative Bacteria
Gerasyuto, Aleksey I, Arnold, Michael A, Wang, Jiashi, Chen, Guangming, Zhang, Xiaoyan, Smith, Sean, Woll, Matthew G, Baird, John, Zhang, Nanjing, Almstead, Neil G, Narasimhan, Jana, Peddi, Srinivasa, Dumble, Melissa, Sheedy, Josephine, Weetall, Marla, Branstrom, Arthur A, Prasad, J. V. N, Karp, Gary M
Published in Journal of medicinal chemistry (24.05.2018)
Published in Journal of medicinal chemistry (24.05.2018)
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4-Hydroxy-2-pyridones: Discovery and evaluation of a novel class of antibacterial agents targeting DNA synthesis
Arnold, Michael A., Gerasyuto, Aleksey I., Wang, Jiashi, Du, Wu, Gorske, Yi Jin Kim, Arasu, Tamil, Baird, John, Almstead, Neil G., Narasimhan, Jana, Peddi, Srinivasa, Ginzburg, Olya, Lue, Stanley W., Hedrick, Jean, Sheedy, Josephine, Lagaud, Guy, Branstrom, Arthur A., Weetall, Marla, Prasad, J.V.N. Vara, Karp, Gary M.
Published in Bioorganic & medicinal chemistry letters (15.11.2017)
Published in Bioorganic & medicinal chemistry letters (15.11.2017)
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Journal Article
Correction to Discovery and Optimization of Indolyl-Containing 4‑Hydroxy-2-pyridone Type II DNA Topoisomerase Inhibitors Active against Multidrug Resistant Gram-Negative Bacteria
Gerasyuto, Aleksey I, Arnold, Michael A, Wang, Jiashi, Chen, Guangming, Zhang, Xiaoyan, Smith, Sean, Woll, Matthew G, Baird, John, Zhang, Nanjing, Almstead, Neil G, Narasimhan, Jana, Peddi, Srinivasa, Dumble, Melissa, Sheedy, Josephine, Weetall, Marla, Branstrom, Arthur A, Prasad, J. V. N, Karp, Gary M
Published in Journal of medicinal chemistry (25.10.2018)
Published in Journal of medicinal chemistry (25.10.2018)
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Stereoselective Formal [3 + 3] Cycloaddition Approach to cis-1-Azadecalins and Synthesis of (−)-4a,8a-diepi-Pumiliotoxin C. Evidence for the First Highly Stereoselective 6π-Electron Electrocyclic Ring Closures of 1-Azatrienes
Sklenicka, Heather M, Hsung, Richard P, McLaughlin, Michael J, Wei, Lin-li, Gerasyuto, Aleksey I, Brennessel, William B
Published in Journal of the American Chemical Society (04.09.2002)
Published in Journal of the American Chemical Society (04.09.2002)
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A Novel and Highly Stereoselective Intramolecular Formal [3+3] Cycloaddition Reaction of Vinylogous Amides Tethered with α,β-Unsaturated Aldehydes: A Formal Total Synthesis of (+)-Gephyrotoxin
Wei, Lin-Li, Hsung, Richard P., Sklenicka, Heather M., Gerasyuto, Aleksey I.
Published in Angewandte Chemie (International ed.) (17.04.2001)
Published in Angewandte Chemie (International ed.) (17.04.2001)
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Total syntheses of enantiomerically enriched R-(+)- and S-(-)-deplancheine
Sydorenko, N, Zificsak, CA, Gerasyuto, AI, Hsung, RP
Published in Organic & biomolecular chemistry (07.06.2005)
Published in Organic & biomolecular chemistry (07.06.2005)
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A Formal [3 + 3] Cycloaddition Reaction. Improved Reactivity Using α,β-Unsaturated Iminium Salts and Evidence for Reversibility of 6π-Electron Electrocyclic Ring Closure of 1-Oxatrienes
Shen, Hong C, Wang, Jiashi, Cole, Kevin P, McLaughlin, Michael J, Morgan, Christopher D, Douglas, Christopher J, Hsung, Richard P, Coverdale, Heather A, Gerasyuto, Aleksey I, Hahn, Juliet M, Liu, Jia, Sklenicka, Heather M, Wei, Lin-Li, Zehnder, Luke R, Zificsak, Craig A
Published in Journal of organic chemistry (07.03.2003)
Published in Journal of organic chemistry (07.03.2003)
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A CYCLIC ACETAL TETHERED INTRAMOLECULAR DIELS-ALDER CYCLOADDITION. STUDIES DIRECTED TOWARD A TOTAL SYNTHESIS OF (+/-)-FUSIDILACTONE C
Ghosh, Sunil K., Wei, Yonggang, Gerasyuto, Aleksey I., Feltenberger, John B., Wang, Jiashi, Hsung, Richard P.
Published in Heterocycles (01.03.2011)
Published in Heterocycles (01.03.2011)
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인간 인테그린 A4B7 억제
CUI DAN, LIN FU YANG, KIM BYUNGCHAN, BURSAVICH MATTHEW G, ROGERS BRUCE N, TROAST DAWN M, HOUANG EVELYNE, KONZE KYLE D, LIPPA BLAISE S, RAFI SALMA, ZAHLER ROBERT, DOWLING JAMES E, HICKEY EUGENE, HARRISON BRYCE A, GERASYUTO ALEKSEY I, DAY TYLER, HAHN KRISTOPHER N, ZHONG CHENG
Year of Publication 19.06.2023
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Year of Publication 19.06.2023
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Highly Stereoselective Formal [3 + 3] Cycloaddition Reactions of Chiral Vinylogous Amides with α,β-Unsaturated Iminiums
Sklenicka, Heather M, Hsung, Richard P, Wei, Lin-Li, McLaughlin, Michael J, Gerasyuto, Aleksey I, Degen, Shane J
Published in Organic letters (20.04.2000)
Published in Organic letters (20.04.2000)
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포스포이노시티드 3-키나제 (PI3K) 조정과 연관된 질환의 치료를 위한 PI3K의 알로스테릭 크로메논 억제제
DAHLGREN MARKUS K, WIDJAJA TIEN, LONG KATELYN FRANCES, MCELLIGOTT DAVID L, ARONOW SEAN DOUGLAS, KNIGHT JENNIFER LYNN, KOLAKOWSKI GABRIELLE R, KLIPPEL GIESE ANKE, ANDERSON ERIN DANIELLE, FENG SHULU, HICKEY EUGENE R, SEVERANCE DANIEL LEE, IRVIN THOMAS COMBS, PUCA LOREDANA, MCLEAN JOHNATHAN ALEXANDER, WELCH MICHAEL BRIAN, MAYNE CHRISTOPHER GLENN, GERASYUTO ALEKSEY I, KUMAR MANOJ, RAVI KANNAN KARUKURICHI, BOYLES NICHOLAS A, KESICKI EDWARD A
Year of Publication 09.12.2022
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Year of Publication 09.12.2022
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인간 인테그린 α4β7의 억제
CUI DAN, LIN FU YANG, KIM BYUNGCHAN, BURSAVICH MATTHEW G, ROGERS BRUCE N, TROAST DAWN M, HOUANG EVELYNE, KONZE KYLE D, LIPPA BLAISE S, RAFI SALMA, ZAHLER ROBERT, DOWLING JAMES E, HICKEY EUGENE, HARRISON BRYCE A, GERASYUTO ALEKSEY I, DAY TYLER, HAHN KRISTOPHER N, ZHONG CHENG
Year of Publication 20.07.2022
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Year of Publication 20.07.2022
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αvβ6 인테그린 억제
SOSA BRIAN, LIN FU YANG, BORTOLATO ANDREA, KIM BYUNGCHAN, BURSAVICH MATTHEW G, ROGERS BRUCE N, TROAST DAWN M, KONZE KYLE D, LIPPA BLAISE S, DOWLING JAMES E, HICKEY EUGENE, HARRISON BRYCE A, GERASYUTO ALEKSEY I, QIAO QI, DAY TYLER, SVENSSON MATS A, HAHN KRISTOPHER N, ZHONG CHENG
Year of Publication 04.06.2021
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Year of Publication 04.06.2021
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