Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases
Miles, Timothy J., Hennessy, Alan J., Bax, Ben, Brooks, Gerald, Brown, Barry S., Brown, Pamela, Cailleau, Nathalie, Chen, Dongzhao, Dabbs, Steven, Davies, David T., Esken, Joel M., Giordano, Ilaria, Hoover, Jennifer L., Jones, Graham E., Kusalakumari Sukmar, Senthill K., Markwell, Roger E., Minthorn, Elisabeth A., Rittenhouse, Steve, Gwynn, Michael N., Pearson, Neil D.
Published in Bioorganic & medicinal chemistry letters (15.05.2016)
Published in Bioorganic & medicinal chemistry letters (15.05.2016)
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Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases
Miles, Timothy J., Hennessy, Alan J., Bax, Ben, Brooks, Gerald, Brown, Barry S., Brown, Pamela, Cailleau, Nathalie, Chen, Dongzhao, Dabbs, Steven, Davies, David T., Esken, Joel M., Giordano, Ilaria, Hoover, Jennifer L., Huang, Jianzhong, Jones, Graham E., Kusalakumari Sukmar, Senthill K., Spitzfaden, Claus, Markwell, Roger E., Minthorn, Elisabeth A., Rittenhouse, Steve, Gwynn, Michael N., Pearson, Neil D.
Published in Bioorganic & medicinal chemistry letters (01.10.2013)
Published in Bioorganic & medicinal chemistry letters (01.10.2013)
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Novel cyclohexyl-amides as potent antibacterials targeting bacterial type IIA topoisomerases
Miles, Timothy J., Barfoot, Christopher, Brooks, Gerald, Brown, Pamela, Chen, Dongzhao, Dabbs, Steven, Davies, David T., Downie, David L., Eyrisch, Susanne, Giordano, Ilaria, Gwynn, Michael N., Hennessy, Alan, Hoover, Jennifer, Huang, Jianzhong, Jones, Graham, Markwell, Roger, Rittenhouse, Stephen, Xiang, Hong, Pearson, Neil
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
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Journal Article
Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases
Miles, Timothy J., Axten, Jeffrey M., Barfoot, Christopher, Brooks, Gerald, Brown, Pamela, Chen, Dongzhao, Dabbs, Steven, Davies, David T., Downie, David L., Eyrisch, Susanne, Gallagher, Timothy, Giordano, Ilaria, Gwynn, Michael N., Hennessy, Alan, Hoover, Jennifer, Huang, Jianzhong, Jones, Graham, Markwell, Roger, Miller, William H., Minthorn, Elizabeth A., Rittenhouse, Stephen, Seefeld, Mark, Pearson, Neil
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
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6-(SUBSTITUTED METHYLENE)PENEMS, POTENT BROAD SPECTRUM INHIBITORS OF BACTERIAL β-LACTAMASE: V. CHIRAL 1, 2, 3-TRIAZOLYL DERIVATIVES
BENNETT, ISABEL S., BROOKS, GERALD, BROOM, NIGEL J. P., CALVERT, STEPHEN H., COLEMAN, KENNETH, FRANÇOIS, IRENE
Published in Journal of antibiotics (1991)
Published in Journal of antibiotics (1991)
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Flexible palladium-catalysed amidation reactions for the synthesis of complex aryl amides
Barfoot, Christopher, Brooks, Gerald, Brown, Pamela, Dabbs, Steven, Davies, David T., Giordano, Ilaria, Hennessy, Alan, Jones, Graham, Markwell, Roger, Miles, Timothy, Pearson, Neil, Smethurst, Christian A.
Published in Tetrahedron letters (19.05.2010)
Published in Tetrahedron letters (19.05.2010)
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The design of efficient and selective routes to pyridyl analogues of 3-oxo-3,4-dihydro-2H-1,4-(benzothiazine or benzoxazine)-6-carbaldehydes
Brooks, Gerald, Dabbs, Steven, Davies, David T., Hennessy, Alan J., Jones, Graham E., Markwell, Roger E., Miles, Timothy J., Owston, Nathan A., Pearson, Neil D., Peng, Tony W.
Published in Tetrahedron letters (22.09.2010)
Published in Tetrahedron letters (22.09.2010)
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The design of efficient and selective routes to a key 1,4- cis-substituted cyclohexylamide intermediate
Barfoot, Christopher, Brooks, Gerald, Davies, David T., Elder, John, Giordano, Ilaria, Hennessy, Alan, Jones, Graham, Markwell, Roger, McGuire, Michael, Miles, Timothy, Pearson, Neil, Spoors, Grant, Sudini, Ravinder, Wei, Hengxu, Wood, Jeffery
Published in Tetrahedron letters (26.05.2010)
Published in Tetrahedron letters (26.05.2010)
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The design of efficient and selective routes to pyridyl analogues of 3-oxo-3,4-dihydro-2 H-1,4-(benzothiazine or benzoxazine)-6-carbaldehydes
Brooks, Gerald, Dabbs, Steven, Davies, David T., Hennessy, Alan J., Jones, Graham E., Markwell, Roger E., Miles, Timothy J., Owston, Nathan A., Pearson, Neil D., Peng, Tony W.
Published in Tetrahedron letters (2010)
Published in Tetrahedron letters (2010)
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Pleuromutilins. Part 1: The identification of novel mutilin 14-carbamates
Brooks, Gerald, Burgess, Wendy, Colthurst, David, Hinks, Jeremy D, Hunt, Eric, Pearson, Michael J, Shea, Burdena, Takle, Andrew K, Wilson, Jennifer M, Woodnutt, Gary
Published in Bioorganic & medicinal chemistry (01.05.2001)
Published in Bioorganic & medicinal chemistry (01.05.2001)
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