Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies
Zhou, Tongqing, Zhu, Jiang, Wu, Xueling, Moquin, Stephanie, Zhang, Baoshan, Acharya, Priyamvada, Georgiev, Ivelin S., Altae-Tran, Han R., Chuang, Gwo-Yu, Joyce, M. Gordon, Do Kwon, Young, Longo, Nancy S., Louder, Mark K., Luongo, Timothy, McKee, Krisha, Schramm, Chaim A., Skinner, Jeff, Yang, Yongping, Yang, Zhongjia, Zhang, Zhenhai, Zheng, Anqi, Bonsignori, Mattia, Haynes, Barton F., Scheid, Johannes F., Nussenzweig, Michel C., Simek, Melissa, Burton, Dennis R., Koff, Wayne C., Mullikin, James C., Connors, Mark, Shapiro, Lawrence, Nabel, Gary J., Mascola, John R., Kwong, Peter D.
Published in Immunity (Cambridge, Mass.) (22.08.2013)
Published in Immunity (Cambridge, Mass.) (22.08.2013)
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High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity
Setliff, Ian, Shiakolas, Andrea R., Pilewski, Kelsey A., Murji, Amyn A., Mapengo, Rutendo E., Janowska, Katarzyna, Richardson, Simone, Oosthuysen, Charissa, Raju, Nagarajan, Ronsard, Larance, Kanekiyo, Masaru, Qin, Juliana S., Kramer, Kevin J., Greenplate, Allison R., McDonnell, Wyatt J., Graham, Barney S., Connors, Mark, Lingwood, Daniel, Acharya, Priyamvada, Morris, Lynn, Georgiev, Ivelin S.
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Published in Cell (12.12.2019)
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Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G
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Published in Cell (05.05.2016)
Published in Cell (05.05.2016)
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Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth
Huang, Jinghe, Kang, Byong H., Ishida, Elise, Zhou, Tongqing, Griesman, Trevor, Sheng, Zizhang, Wu, Fan, Doria-Rose, Nicole A., Zhang, Baoshan, McKee, Krisha, O’Dell, Sijy, Chuang, Gwo-Yu, Druz, Aliaksandr, Georgiev, Ivelin S., Schramm, Chaim A., Zheng, Anqi, Joyce, M. Gordon, Asokan, Mangaiarkarasi, Ransier, Amy, Darko, Sam, Migueles, Stephen A., Bailer, Robert T., Louder, Mark K., Alam, S. Munir, Parks, Robert, Kelsoe, Garnett, Von Holle, Tarra, Haynes, Barton F., Douek, Daniel C., Hirsch, Vanessa, Seaman, Michael S., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D., Connors, Mark
Published in Immunity (Cambridge, Mass.) (15.11.2016)
Published in Immunity (Cambridge, Mass.) (15.11.2016)
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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization
Klein, Florian, Diskin, Ron, Scheid, Johannes F., Gaebler, Christian, Mouquet, Hugo, Georgiev, Ivelin S., Pancera, Marie, Zhou, Tongqing, Incesu, Reha-Baris, Fu, Brooks Zhongzheng, Gnanapragasam, Priyanthi N.P., Oliveira, Thiago Y., Seaman, Michael S., Kwong, Peter D., Bjorkman, Pamela J., Nussenzweig, Michel C.
Published in Cell (28.03.2013)
Published in Cell (28.03.2013)
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Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site
Crooks, Ema T, Tong, Tommy, Chakrabarti, Bimal, Narayan, Kristin, Georgiev, Ivelin S, Menis, Sergey, Huang, Xiaoxing, Kulp, Daniel, Osawa, Keiko, Muranaka, Janelle, Stewart-Jones, Guillaume, Destefano, Joanne, O'Dell, Sijy, LaBranche, Celia, Robinson, James E, Montefiori, David C, McKee, Krisha, Du, Sean X, Doria-Rose, Nicole, Kwong, Peter D, Mascola, John R, Zhu, Ping, Schief, William R, Wyatt, Richard T, Whalen, Robert G, Binley, James M
Published in PLoS pathogens (01.05.2015)
Published in PLoS pathogens (01.05.2015)
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Structure and immune recognition of trimeric pre-fusion HIV-1 Env
Pancera, Marie, Zhou, Tongqing, Druz, Aliaksandr, Georgiev, Ivelin S, Soto, Cinque, Gorman, Jason, Huang, Jinghe, Acharya, Priyamvada, Chuang, Gwo-Yu, Ofek, Gilad, Stewart-Jones, Guillaume B E, Stuckey, Jonathan, Bailer, Robert T, Joyce, M Gordon, Louder, Mark K, Tumba, Nancy, Yang, Yongping, Zhang, Baoshan, Cohen, Myron S, Haynes, Barton F, Mascola, John R, Morris, Lynn, Munro, James B, Blanchard, Scott C, Mothes, Walther, Connors, Mark, Kwong, Peter D
Published in Nature (London) (23.10.2014)
Published in Nature (London) (23.10.2014)
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Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope
Schoofs, Till, Barnes, Christopher O., Suh-Toma, Nina, Golijanin, Jovana, Schommers, Philipp, Gruell, Henning, West, Anthony P., Bach, Franziska, Lee, Yu Erica, Nogueira, Lilian, Georgiev, Ivelin S., Bailer, Robert T., Czartoski, Julie, Mascola, John R., Seaman, Michael S., McElrath, M. Juliana, Doria-Rose, Nicole A., Klein, Florian, Nussenzweig, Michel C., Bjorkman, Pamela J.
Published in Immunity (Cambridge, Mass.) (18.06.2019)
Published in Immunity (Cambridge, Mass.) (18.06.2019)
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Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection
Setliff, Ian, McDonnell, Wyatt J., Raju, Nagarajan, Bombardi, Robin G., Murji, Amyn A., Scheepers, Cathrine, Ziki, Rutendo, Mynhardt, Charissa, Shepherd, Bryan E., Mamchak, Alusha A., Garrett, Nigel, Karim, Salim Abdool, Mallal, Simon A., Crowe, James E., Morris, Lynn, Georgiev, Ivelin S.
Published in Cell host & microbe (13.06.2018)
Published in Cell host & microbe (13.06.2018)
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Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors
González, Nuria, McKee, Krisha, Lynch, Rebecca M, Georgiev, Ivelin S, Jimenez, Laura, Grau, Eulalia, Yuste, Eloísa, Kwong, Peter D, Mascola, John R, Alcamí, José
Published in PloS one (20.03.2018)
Published in PloS one (20.03.2018)
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Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses
Kanekiyo, Masaru, Joyce, M Gordon, Gillespie, Rebecca A, Gallagher, John R, Andrews, Sarah F, Yassine, Hadi M, Wheatley, Adam K, Fisher, Brian E, Ambrozak, David R, Creanga, Adrian, Leung, Kwanyee, Yang, Eun Sung, Boyoglu-Barnum, Seyhan, Georgiev, Ivelin S, Tsybovsky, Yaroslav, Prabhakaran, Madhu S, Andersen, Hanne, Kong, Wing-Pui, Baxa, Ulrich, Zephir, Kathryn L, Ledgerwood, Julie E, Koup, Richard A, Kwong, Peter D, Harris, Audray K, McDermott, Adrian B, Mascola, John R, Graham, Barney S
Published in Nature immunology (01.03.2019)
Published in Nature immunology (01.03.2019)
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Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface
Huang, Jinghe, Kang, Byong H, Pancera, Marie, Lee, Jeong Hyun, Tong, Tommy, Feng, Yu, Imamichi, Hiromi, Georgiev, Ivelin S, Chuang, Gwo-Yu, Druz, Aliaksandr, Doria-Rose, Nicole A, Laub, Leo, Sliepen, Kwinten, van Gils, Marit J, de la Peña, Alba Torrents, Derking, Ronald, Klasse, Per-Johan, Migueles, Stephen A, Bailer, Robert T, Alam, Munir, Pugach, Pavel, Haynes, Barton F, Wyatt, Richard T, Sanders, Rogier W, Binley, James M, Ward, Andrew B, Mascola, John R, Kwong, Peter D, Connors, Mark
Published in Nature (London) (06.11.2014)
Published in Nature (London) (06.11.2014)
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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01
Zhou, Tongqing, Georgiev, Ivelin, Wu, Xueling, Yang, Zhi-Yong, Dai, Kaifan, Finzi, Andrés, Do Kwon, Young, Scheid, Johannes F, Shi, Wei, Xu, Ling, Yang, Yongping, Zhu, Jiang, Nussenzweig, Michel C, Sodroski, Joseph, Shapiro, Lawrence, Nabel, Gary J, Mascola, John R, Kwong, Peter D
Published in Science (American Association for the Advancement of Science) (13.08.2010)
Published in Science (American Association for the Advancement of Science) (13.08.2010)
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Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies
Kepler, Thomas B., Liao, Hua-Xin, Alam, S. Munir, Bhaskarabhatla, Rekha, Zhang, Ruijun, Yandava, Chandri, Stewart, Shelley, Anasti, Kara, Kelsoe, Garnett, Parks, Robert, Lloyd, Krissey E., Stolarchuk, Christina, Pritchett, Jamie, Solomon, Erika, Friberg, Emma, Morris, Lynn, Karim, Salim S. Abdool, Cohen, Myron S., Walter, Emmanuel, Moody, M. Anthony, Wu, Xueling, Altae-Tran, Han R., Georgiev, Ivelin S., Kwong, Peter D., Boyd, Scott D., Fire, Andrew Z., Mascola, John R., Haynes, Barton F.
Published in Cell host & microbe (10.09.2014)
Published in Cell host & microbe (10.09.2014)
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Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody
Kong, Rui, Xu, Kai, Zhou, Tongqing, Acharya, Priyamvada, Lemmin, Thomas, Liu, Kevin, Ozorowski, Gabriel, Soto, Cinque, Taft, Justin D., Bailer, Robert T., Cale, Evan M., Chen, Lei, Choi, Chang W., Chuang, Gwo-Yu, Doria-Rose, Nicole A., Druz, Aliaksandr, Georgiev, Ivelin S., Gorman, Jason, Huang, Jinghe, Joyce, M. Gordon, Louder, Mark K., Ma, Xiaochu, McKee, Krisha, O'Dell, Sijy, Pancera, Marie, Yang, Yongping, Blanchard, Scott C., Mothes, Walther, Burton, Dennis R., Koff, Wayne C., Connors, Mark, Ward, Andrew B., Kwong, Peter D., Mascola, John R.
Published in Science (American Association for the Advancement of Science) (13.05.2016)
Published in Science (American Association for the Advancement of Science) (13.05.2016)
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Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine
Kramer, Kevin J, Wilfong, Erin M, Voss, Kelsey, Barone, Sierra M, Shiakolas, Andrea R, Raju, Nagarajan, Roe, Caroline E, Suryadevara, Naveenchandra, Walker, Lauren M, Wall, Steven C, Paulo, Ariana, Schaefer, Samuel, Dahunsi, Debolanle, Westlake, Camille S, Crowe, Jr, James E, Carnahan, Robert H, Rathmell, Jeffrey C, Bonami, Rachel H, Georgiev, Ivelin S, Irish, Jonathan M
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Published in Nature communications (16.06.2022)
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Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires
Tian, Ming, Cheng, Cheng, Chen, Xuejun, Duan, Hongying, Cheng, Hwei-Ling, Dao, Mai, Sheng, Zizhang, Kimble, Michael, Wang, Lingshu, Lin, Sherry, Schmidt, Stephen D., Du, Zhou, Joyce, M. Gordon, Chen, Yiwei, DeKosky, Brandon J., Chen, Yimin, Normandin, Erica, Cantor, Elizabeth, Chen, Rita E., Doria-Rose, Nicole A., Zhang, Yi, Shi, Wei, Kong, Wing-Pui, Choe, Misook, Henry, Amy R., Laboune, Farida, Georgiev, Ivelin S., Huang, Pei-Yi, Jain, Suvi, McGuire, Andrew T., Georgeson, Eric, Menis, Sergey, Douek, Daniel C., Schief, William R., Stamatatos, Leonidas, Kwong, Peter D., Shapiro, Lawrence, Haynes, Barton F., Mascola, John R., Alt, Frederick W.
Published in Cell (08.09.2016)
Published in Cell (08.09.2016)
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Prediction of VRC01 neutralization sensitivity by HIV-1 gp160 sequence features
Magaret, Craig A, Benkeser, David C, Williamson, Brian D, Borate, Bhavesh R, Carpp, Lindsay N, Georgiev, Ivelin S, Setliff, Ian, Dingens, Adam S, Simon, Noah, Carone, Marco, Simpkins, Christopher, Montefiori, David, Alter, Galit, Yu, Wen-Han, Juraska, Michal, Edlefsen, Paul T, Karuna, Shelly, Mgodi, Nyaradzo M, Edugupanti, Srilatha, Gilbert, Peter B
Published in PLoS computational biology (01.04.2019)
Published in PLoS computational biology (01.04.2019)
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Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV
Joyce, M Gordon, Zhang, Baoshan, Ou, Li, Chen, Man, Chuang, Gwo-Yu, Druz, Aliaksandr, Kong, Wing-Pui, Lai, Yen-Ting, Rundlet, Emily J, Tsybovsky, Yaroslav, Yang, Yongping, Georgiev, Ivelin S, Guttman, Miklos, Lees, Christopher R, Pancera, Marie, Sastry, Mallika, Soto, Cinque, Stewart-Jones, Guillaume B E, Thomas, Paul V, Van Galen, Joseph G, Baxa, Ulrich, Lee, Kelly K, Mascola, John R, Graham, Barney S, Kwong, Peter D
Published in Nature structural & molecular biology (01.09.2016)
Published in Nature structural & molecular biology (01.09.2016)
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